Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368698 (CHEMBL4161906) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368757 (CHEMBL4169829) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368693 (CHEMBL4171521) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50365388 (CHEMBL4165362) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM308636 (BDBM308807 | US9656955, Example 150 | trans-N-[2-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368701 (CHEMBL4173657) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368752 (CHEMBL4166406) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368702 (CHEMBL4161781) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368692 (CHEMBL4165340) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368759 (CHEMBL4159998) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368767 (CHEMBL4163697) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM309129 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM308813 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50365371 (CHEMBL4168242) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50366117 (CHEMBL4176089) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM50045892 (2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Foundation for Medical Education and Research Curated by ChEMBL | Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells | J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368758 (CHEMBL4173253) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM294231 (US9586942, 5*) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368771 (CHEMBL4166296) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368699 (CHEMBL4167917) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50366116 (CHEMBL4174148) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50365378 (CHEMBL4160468) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50365372 (CHEMBL4176431) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM309315 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM141044 (US8653100, 4) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368760 (CHEMBL4164744) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM50045882 (2-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-N,N...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Foundation for Medical Education and Research Curated by ChEMBL | Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells | J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368697 (CHEMBL4162953) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM50045880 (2-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-N,N...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Foundation for Medical Education and Research Curated by ChEMBL | Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells | J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM308815 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM50045878 (2-(5-Chloro-2-phenyl-1H-indol-3-yl)-N,N-dihexyl-ac...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Foundation for Medical Education and Research Curated by ChEMBL | Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells | J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM50045877 (2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Foundation for Medical Education and Research Curated by ChEMBL | Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells | J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50365385 (CHEMBL4166232) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM308876 (N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368783 (CHEMBL4165214) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50365377 (CHEMBL4161927) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM50045883 (CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Foundation for Medical Education and Research Curated by ChEMBL | Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells | J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50365375 (CHEMBL4162798) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM308854 (N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imid...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s... | J Med Chem 61: 7486-7502 (2018) Article DOI: 10.1021/acs.jmedchem.8b00295 BindingDB Entry DOI: 10.7270/Q2CC137K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM50368695 (CHEMBL4172640) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [3H]N-Methyl-SSR504734 from human GlyT1c expressed in cell membranes incubated for 1 hr by liquid scintillation spectrometry | J Med Chem 61: 7503-7524 (2018) Article DOI: 10.1021/acs.jmedchem.8b00300 BindingDB Entry DOI: 10.7270/Q2W66P9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Translocator protein (Rattus norvegicus (rat)) | BDBM50045894 (CHEMBL98081 | N,N-Dihexyl-2-(2-phenyl-1H-indol-3-y...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mayo Foundation for Medical Education and Research Curated by ChEMBL | Assay Description Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cells | J Med Chem 36: 2908-20 (1993) BindingDB Entry DOI: 10.7270/Q2C24VGV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM308815 ((3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309027 ((3R,4S)-N-hexyl-1-[(1-methyl-1H-imidazol-4-yl)sulf...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309049 ((3R,4S)-N-[(2,5-dichlorothiophen-3-yl)methyl]-1-[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309095 (5-chloro-N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309103 (4-{[(3S,4R)-3-(4-fluorophenyl)-4-(hexyloxy)pyrroli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309106 (Trans-N-(3-chlorobenzyl)-4-(4-fluorophenyl)-1-[(1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309109 (Trans-N-(3,4-difluorobenzyl)-4-(4-fluorophenyl)-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309120 (Trans-N-(3-chloro-4-fluorobenzyl)-4-(4-fluoropheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human)) | BDBM309123 ((3R,4S)-N-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent | Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me... | US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48 | |||||||||||
More data for this Ligand-Target Pair |
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