Compile Data Set for Download or QSAR

Found 145 hits with Last Name = 'brough' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026849 (CHEMBL1957231) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccn2ccnc2c1 Show InChI InChI=1S/C19H15ClN4O3/c1-26-15-3-2-13(9-14(15)20)18-17(23-11-27-18)19(25)22-10-12-4-6-24-7-5-21-16(24)8-12/h2-9,11H,10H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418989 (CHEMBL1809113) Show SMILES Fc1ccc(cc1-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1)C#N Show InChI InChI=1S/C19H10FN3OS/c20-16-2-1-11(9-21)7-13(16)15-10-23-19(24)14-8-17(25-18(14)15)12-3-5-22-6-4-12/h1-8,10H,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418990 (CHEMBL1809114) Show SMILES O=c1[nH]cc(-c2ccc3OCCOc3c2)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C20H14N2O3S/c23-20-14-10-18(12-3-5-21-6-4-12)26-19(14)15(11-22-20)13-1-2-16-17(9-13)25-8-7-24-16/h1-6,9-11H,7-8H2,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418991 (CHEMBL1809115) Show SMILES O=c1[nH]cc(-c2cccc(CC#N)c2)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C20H13N3OS/c21-7-4-13-2-1-3-15(10-13)17-12-23-20(24)16-11-18(25-19(16)17)14-5-8-22-9-6-14/h1-3,5-6,8-12H,4H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418992 (CHEMBL1809116) Show SMILES Clc1cccc(n1)-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1 Show InChI InChI=1S/C17H10ClN3OS/c18-15-3-1-2-13(21-15)12-9-20-17(22)11-8-14(23-16(11)12)10-4-6-19-7-5-10/h1-9H,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418998 (CHEMBL1809117) Show SMILES O=c1[nH]cc(-c2cscc2C#N)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C17H9N3OS2/c18-6-11-8-22-9-14(11)13-7-20-17(21)12-5-15(23-16(12)13)10-1-3-19-4-2-10/h1-5,7-9H,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418987 (CHEMBL1809110) Show SMILES O=c1[nH]cc(-c2ccc(cc2)N2CCOCC2)c2sc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H18N4O2S/c25-20-16-9-18(14-10-22-23-11-14)27-19(16)17(12-21-20)13-1-3-15(4-2-13)24-5-7-26-8-6-24/h1-4,9-12H,5-8H2,(H,21,25)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human full length His-tagged GSK3-beta expressed in baculovirus by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026867 (CHEMBL1957091) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H14ClN3O3/c1-23-14-3-2-12(8-13(14)18)16-15(21-10-24-16)17(22)20-9-11-4-6-19-7-5-11/h2-8,10H,9H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418986 (CHEMBL1809109) Show SMILES CS(=O)(=O)Nc1cccc(c1)-c1c[nH]c(=O)c2cc(sc12)-c1ccnc2[nH]ccc12 Show InChI InChI=1S/C21H16N4O3S2/c1-30(27,28)25-13-4-2-3-12(9-13)17-11-24-21(26)16-10-18(29-19(16)17)14-5-7-22-20-15(14)6-8-23-20/h2-11,25H,1H3,(H,22,23)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human full length His-tagged GSK3-beta expressed in baculovirus by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026862 (CHEMBL1957230) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCCc1ccncc1 Show InChI InChI=1S/C18H16ClN3O3/c1-24-15-3-2-13(10-14(15)19)17-16(22-11-25-17)18(23)21-9-6-12-4-7-20-8-5-12/h2-5,7-8,10-11H,6,9H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026830 (CHEMBL1957102) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccnc(Cl)c1 Show InChI InChI=1S/C17H13Cl2N3O3/c1-24-13-3-2-11(7-12(13)18)16-15(22-9-25-16)17(23)21-8-10-4-5-20-14(19)6-10/h2-7,9H,8H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026837 (CHEMBL1957228) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccnnc1 Show InChI InChI=1S/C16H13ClN4O3/c1-23-13-3-2-11(6-12(13)17)15-14(19-9-24-15)16(22)18-7-10-4-5-20-21-8-10/h2-6,8-9H,7H2,1H3,(H,18,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026834 (CHEMBL1957226) Show SMILES COc1cc(CNC(=O)c2ncoc2-c2ccc(OC)c(Cl)c2)ccn1 Show InChI InChI=1S/C18H16ClN3O4/c1-24-14-4-3-12(8-13(14)19)17-16(22-10-26-17)18(23)21-9-11-5-6-20-15(7-11)25-2/h3-8,10H,9H2,1-2H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026832 (CHEMBL1957225) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccnc(C)c1 Show InChI InChI=1S/C18H16ClN3O3/c1-11-7-12(5-6-20-11)9-21-18(23)16-17(25-10-22-16)13-3-4-15(24-2)14(19)8-13/h3-8,10H,9H2,1-2H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026850 (CHEMBL1957092) Show SMILES COc1ccc(cc1F)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H14FN3O3/c1-23-14-3-2-12(8-13(14)18)16-15(21-10-24-16)17(22)20-9-11-4-6-19-7-5-11/h2-8,10H,9H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026840 (CHEMBL1957229) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccnc(C)n1 Show InChI InChI=1S/C17H15ClN4O3/c1-10-19-6-5-12(22-10)8-20-17(23)15-16(25-9-21-15)11-3-4-14(24-2)13(18)7-11/h3-7,9H,8H2,1-2H3,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026841 (CHEMBL1957099) Show SMILES COc1ncc(cc1Cl)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C16H13ClN4O3/c1-23-16-12(17)6-11(8-20-16)14-13(21-9-24-14)15(22)19-7-10-2-4-18-5-3-10/h2-6,8-9H,7H2,1H3,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50419000 (CHEMBL1809107) Show SMILES O=c1[nH]cc(-c2ccc(cc2)N2CCOCC2)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C22H19N3O2S/c26-22-18-13-20(16-5-7-23-8-6-16)28-21(18)19(14-24-22)15-1-3-17(4-2-15)25-9-11-27-12-10-25/h1-8,13-14H,9-12H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human full length His-tagged GSK3-beta expressed in baculovirus by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50365426 (CHEMBL1957085) Show SMILES COc1ccc(cc1)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H15N3O3/c1-22-14-4-2-13(3-5-14)16-15(20-11-23-16)17(21)19-10-12-6-8-18-9-7-12/h2-9,11H,10H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026861 (CHEMBL1957098) Show SMILES COc1ccc(cn1)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C16H14N4O3/c1-22-13-3-2-12(9-18-13)15-14(20-10-23-15)16(21)19-8-11-4-6-17-7-5-11/h2-7,9-10H,8H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418989 (CHEMBL1809113) Show SMILES Fc1ccc(cc1-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1)C#N Show InChI InChI=1S/C19H10FN3OS/c20-16-2-1-11(9-21)7-13(16)15-10-23-19(24)14-8-17(25-18(14)15)12-3-5-22-6-4-12/h1-8,10H,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human flag-tagged GSK3-beta expressed in HEK-MSRII cells assessed as CRMP-2 phosphorylation by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026836 (CHEMBL1957227) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccnc(c1)C(F)(F)F Show InChI InChI=1S/C18H13ClF3N3O3/c1-27-13-3-2-11(7-12(13)19)16-15(25-9-28-16)17(26)24-8-10-4-5-23-14(6-10)18(20,21)22/h2-7,9H,8H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418999 (CHEMBL1809118) Show SMILES COCc1ccccc1-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1 Show InChI InChI=1S/C20H16N2O2S/c1-24-12-14-4-2-3-5-15(14)17-11-22-20(23)16-10-18(25-19(16)17)13-6-8-21-9-7-13/h2-11H,12H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418993 (CHEMBL1809119) Show SMILES CCOc1ccc(cn1)-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1 Show InChI InChI=1S/C19H15N3O2S/c1-2-24-17-4-3-13(10-21-17)15-11-22-19(23)14-9-16(25-18(14)15)12-5-7-20-8-6-12/h3-11H,2H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50419004 (CHEMBL1738953) Show SMILES Oc1ccc(cc1)-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1 Show InChI InChI=1S/C18H12N2O2S/c21-13-3-1-11(2-4-13)15-10-20-18(22)14-9-16(23-17(14)15)12-5-7-19-8-6-12/h1-10,21H,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50419001 (CHEMBL1738951) Show SMILES O=c1[nH]ccc2oc(cc12)-c1ccncc1 Show InChI InChI=1S/C12H8N2O2/c15-12-9-7-11(8-1-4-13-5-2-8)16-10(9)3-6-14-12/h1-7H,(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418994 (CHEMBL1809120) Show SMILES COc1cc(F)ccc1-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1 Show InChI InChI=1S/C19H13FN2O2S/c1-24-16-8-12(20)2-3-13(16)15-10-22-19(23)14-9-17(25-18(14)15)11-4-6-21-7-5-11/h2-10H,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50418998 (CHEMBL1809117) Show SMILES O=c1[nH]cc(-c2cscc2C#N)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C17H9N3OS2/c18-6-11-8-22-9-14(11)13-7-20-17(21)12-5-15(23-16(12)13)10-1-3-19-4-2-10/h1-5,7-9H,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant CDK2 expressed in baculovirus using [gamma-32P]-ATP by 33-P leadseeker assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50419003 (CHEMBL1738952) Show SMILES Brc1c[nH]c(=O)c2cc(sc12)-c1ccncc1 Show InChI InChI=1S/C12H7BrN2OS/c13-9-6-15-12(16)8-5-10(17-11(8)9)7-1-3-14-4-2-7/h1-6H,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human full length His-tagged GSK3-beta expressed in baculovirus by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50418989 (CHEMBL1809113) Show SMILES Fc1ccc(cc1-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1)C#N Show InChI InChI=1S/C19H10FN3OS/c20-16-2-1-11(9-21)7-13(16)15-10-23-19(24)14-8-17(25-18(14)15)12-3-5-22-6-4-12/h1-8,10H,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant CDK2 expressed in baculovirus using [gamma-32P]-ATP by 33-P leadseeker assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026846 (CHEMBL1957080) Show SMILES CNC(=O)c1ccc(CNC(=O)c2ncoc2-c2ccc(OC)cc2)cc1 Show InChI InChI=1S/C20H19N3O4/c1-21-19(24)15-5-3-13(4-6-15)11-22-20(25)17-18(27-12-23-17)14-7-9-16(26-2)10-8-14/h3-10,12H,11H2,1-2H3,(H,21,24)(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GSK3-beta by fluorescence polarization assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026835 (CHEMBL1957084) Show SMILES COc1ccc(cc1)-c1ocnc1C(=O)NCc1cccnc1 Show InChI InChI=1S/C17H15N3O3/c1-22-14-6-4-13(5-7-14)16-15(20-11-23-16)17(21)19-10-12-3-2-8-18-9-12/h2-9,11H,10H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GSK3-beta by fluorescence polarization assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418988 (CHEMBL1809111) Show SMILES Cn1cc(-c2ccc(cc2)N2CCOCC2)c2sc(cc2c1=O)-c1ccncc1 Show InChI InChI=1S/C23H21N3O2S/c1-25-15-20(16-2-4-18(5-3-16)26-10-12-28-13-11-26)22-19(23(25)27)14-21(29-22)17-6-8-24-9-7-17/h2-9,14-15H,10-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human full length His-tagged GSK3-beta expressed in baculovirus by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50418987 (CHEMBL1809110) Show SMILES O=c1[nH]cc(-c2ccc(cc2)N2CCOCC2)c2sc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H18N4O2S/c25-20-16-9-18(14-10-22-23-11-14)27-19(16)17(12-21-20)13-1-3-15(4-2-13)24-5-7-26-8-6-24/h1-4,9-12H,5-8H2,(H,21,25)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant CDK2 expressed in baculovirus using [gamma-32P]-ATP by 33-P leadseeker assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026845 (CHEMBL1957079) Show SMILES COc1ccc(cc1)-c1ocnc1C(=O)NCC1CCC(CC1)C(=O)N(C)C |(25.74,-6.11,;27.07,-5.34,;27.07,-3.8,;25.74,-3.03,;25.74,-1.49,;27.07,-.71,;28.41,-1.48,;28.41,-3.03,;27.07,.82,;28.31,1.73,;27.83,3.2,;26.29,3.19,;25.82,1.73,;24.48,.97,;24.46,-.57,;23.15,1.76,;21.81,1,;20.48,1.79,;20.5,3.34,;19.19,4.12,;17.84,3.38,;17.82,1.83,;19.14,1.04,;16.52,4.17,;16.54,5.71,;15.17,3.42,;13.85,4.21,;15.15,1.88,)| Show InChI InChI=1S/C21H27N3O4/c1-24(2)21(26)16-6-4-14(5-7-16)12-22-20(25)18-19(28-13-23-18)15-8-10-17(27-3)11-9-15/h8-11,13-14,16H,4-7,12H2,1-3H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GSK3-beta by fluorescence polarization assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026843 (CHEMBL1957078) Show SMILES CNC(=O)C1CCC(CNC(=O)c2ncoc2-c2ccc(OC)cc2)CC1 |(-8.29,3.86,;-6.97,3.07,;-5.63,3.82,;-5.6,5.36,;-4.3,3.03,;-2.96,3.78,;-1.64,3,;-1.66,1.45,;-.33,.66,;1.01,1.42,;2.33,.63,;2.32,-.91,;3.68,1.38,;4.15,2.85,;5.69,2.85,;6.17,1.39,;4.92,.48,;4.93,-1.06,;3.6,-1.83,;3.6,-3.37,;4.93,-4.14,;4.93,-5.68,;3.6,-6.45,;6.27,-3.37,;6.26,-1.82,;-3,.7,;-4.33,1.49,)| Show InChI InChI=1S/C20H25N3O4/c1-21-19(24)15-5-3-13(4-6-15)11-22-20(25)17-18(27-12-23-17)14-7-9-16(26-2)10-8-14/h7-10,12-13,15H,3-6,11H2,1-2H3,(H,21,24)(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GSK3-beta by fluorescence polarization assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418998 (CHEMBL1809117) Show SMILES O=c1[nH]cc(-c2cscc2C#N)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C17H9N3OS2/c18-6-11-8-22-9-14(11)13-7-20-17(21)12-5-15(23-16(12)13)10-1-3-19-4-2-10/h1-5,7-9H,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human flag-tagged GSK3-beta expressed in HEK-MSRII cells assessed as CRMP-2 phosphorylation by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418995 (CHEMBL1809121) Show SMILES CN(C)C(=O)c1ccccc1-c1c[nH]c(=O)c2cc(sc12)-c1ccncc1 Show InChI InChI=1S/C21H17N3O2S/c1-24(2)21(26)15-6-4-3-5-14(15)17-12-23-20(25)16-11-18(27-19(16)17)13-7-9-22-10-8-13/h3-12H,1-2H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418996 (CHEMBL1809122) Show SMILES O=c1[nH]cc(-c2cccc3cccnc23)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C21H13N3OS/c25-21-16-11-18(13-6-9-22-10-7-13)26-20(16)17(12-24-21)15-5-1-3-14-4-2-8-23-19(14)15/h1-12H,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026851 (CHEMBL1957093) Show SMILES COc1ccc(-c2ocnc2C(=O)NCc2ccncc2)c(F)c1 Show InChI InChI=1S/C17H14FN3O3/c1-23-12-2-3-13(14(18)8-12)16-15(21-10-24-16)17(22)20-9-11-4-6-19-7-5-11/h2-8,10H,9H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50026842 (CHEMBL1957100) Show SMILES COc1ccc(nc1Cl)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C16H13ClN4O3/c1-23-12-3-2-11(21-15(12)17)14-13(20-9-24-14)16(22)19-8-10-4-6-18-7-5-10/h2-7,9H,8H2,1H3,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of catalytic activity of GSK3-beta by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50365426 (CHEMBL1957085) Show SMILES COc1ccc(cc1)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H15N3O3/c1-22-14-4-2-13(3-5-14)16-15(20-11-23-16)17(21)19-10-12-6-8-18-9-7-12/h2-9,11H,10H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of GSK3-beta by fluorescence polarization assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418987 (CHEMBL1809110) Show SMILES O=c1[nH]cc(-c2ccc(cc2)N2CCOCC2)c2sc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H18N4O2S/c25-20-16-9-18(14-10-22-23-11-14)27-19(16)17(12-21-20)13-1-3-15(4-2-13)24-5-7-26-8-6-24/h1-4,9-12H,5-8H2,(H,21,25)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human flag-tagged GSK3-beta expressed in HEK-MSRII cells assessed as CRMP-2 phosphorylation by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50026837 (CHEMBL1957228) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccnnc1 Show InChI InChI=1S/C16H13ClN4O3/c1-23-13-3-2-11(6-12(13)17)15-14(19-9-24-15)16(22)18-7-10-4-5-20-21-8-10/h2-6,8-9H,7H2,1H3,(H,18,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CDK2 by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50026867 (CHEMBL1957091) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H14ClN3O3/c1-23-14-3-2-12(8-13(14)18)16-15(21-10-24-16)17(22)20-9-11-4-6-19-7-5-11/h2-8,10H,9H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CDK2 by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50026850 (CHEMBL1957092) Show SMILES COc1ccc(cc1F)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H14FN3O3/c1-23-14-3-2-12(8-13(14)18)16-15(21-10-24-16)17(22)20-9-11-4-6-19-7-5-11/h2-8,10H,9H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CDK2 by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50365426 (CHEMBL1957085) Show SMILES COc1ccc(cc1)-c1ocnc1C(=O)NCc1ccncc1 Show InChI InChI=1S/C17H15N3O3/c1-22-14-4-2-13(3-5-14)16-15(20-11-23-16)17(21)19-10-12-6-8-18-9-7-12/h2-9,11H,10H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CDK2 by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50026849 (CHEMBL1957231) Show SMILES COc1ccc(cc1Cl)-c1ocnc1C(=O)NCc1ccn2ccnc2c1 Show InChI InChI=1S/C19H15ClN4O3/c1-26-15-3-2-13(9-14(15)20)18-17(23-11-27-18)19(25)22-10-12-4-6-24-7-5-21-16(24)8-12/h2-9,11H,10H2,1H3,(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CDK2 by AlphaLISA assay				Bioorg Med Chem Lett 22: 1989-94 (2012) Article DOI: 10.1016/j.bmcl.2012.01.034 BindingDB Entry DOI: 10.7270/Q2ZP46KT
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50419000 (CHEMBL1809107) Show SMILES O=c1[nH]cc(-c2ccc(cc2)N2CCOCC2)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C22H19N3O2S/c26-22-18-13-20(16-5-7-23-8-6-16)28-21(18)19(14-24-22)15-1-3-17(4-2-15)25-9-11-27-12-10-25/h1-8,13-14H,9-12H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human GSK3-beta expressed in baculovirus by fluorescence polarization assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50418991 (CHEMBL1809115) Show SMILES O=c1[nH]cc(-c2cccc(CC#N)c2)c2sc(cc12)-c1ccncc1 Show InChI InChI=1S/C20H13N3OS/c21-7-4-13-2-1-3-15(10-13)17-12-23-20(24)16-11-18(25-19(16)17)14-5-8-22-9-6-14/h1-3,5-6,8-12H,4H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human flag-tagged GSK3-beta expressed in HEK-MSRII cells assessed as CRMP-2 phosphorylation by alphaLISA assay				Bioorg Med Chem Lett 21: 4823-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.050 BindingDB Entry DOI: 10.7270/Q2GB2598
					More data for this Ligand-Target Pair

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