Compile Data Set for Download or QSAR

Found 149 hits with Last Name = 'chen' and Initial = 'aya'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516404 (CHEMBL4439823) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC(=O)C(O)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C30H25F12NO5/c1-15(2)47-22-12-17(8-9-21(22)32)26(14-16-6-4-3-5-7-16,18-10-19(31)13-20(11-18)48-28(35,36)25(33)34)43-24(45)23(44)27(46,29(37,38)39)30(40,41)42/h3-13,15,23,25,44,46H,14H2,1-2H3,(H,43,45)/t23?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178701 (CHEMBL3814374) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC[C@H](O)CC(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C29H28F9NO3/c1-17(2)41-25-12-19(8-9-24(25)31)27(14-18-6-4-3-5-7-18,39-16-22(40)15-28(34,35)36)20-10-21(30)13-23(11-20)42-29(37,38)26(32)33/h3-13,17,22,26,39-40H,14-16H2,1-2H3/t22-,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178698 (CHEMBL3813720) Show SMILES OC(CN[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)CC(F)(F)F |r| Show InChI InChI=1S/C25H21ClF8N2O2/c26-17-6-7-21(35-13-17)23(11-15-4-2-1-3-5-15,36-14-19(37)12-24(30,31)32)16-8-18(27)10-20(9-16)38-25(33,34)22(28)29/h1-10,13,19,22,36-37H,11-12,14H2/t19?,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178699 (CHEMBL3813836) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC[C@@H](O)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C28H26F9NO3/c1-16(2)40-23-12-18(8-9-22(23)30)26(14-17-6-4-3-5-7-17,38-15-24(39)27(33,34)35)19-10-20(29)13-21(11-19)41-28(36,37)25(31)32/h3-13,16,24-25,38-39H,14-15H2,1-2H3/t24-,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516410 (CHEMBL4574163) Show SMILES NC(C(=O)N[C@](Cc1ccccc1)(c1ccc(F)c(OC2CC2)c1)c1cc(F)cc(OC(F)(F)C(F)F)c1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C30H24F12N2O4/c31-18-10-17(11-20(13-18)48-28(35,36)25(33)34)26(14-15-4-2-1-3-5-15,16-6-9-21(32)22(12-16)47-19-7-8-19)44-24(45)23(43)27(46,29(37,38)39)30(40,41)42/h1-6,9-13,19,23,25,46H,7-8,14,43H2,(H,44,45)/t23?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178702 (CHEMBL3814963) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC[C@@H](O)CC(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C29H28F9NO3/c1-17(2)41-25-12-19(8-9-24(25)31)27(14-18-6-4-3-5-7-18,39-16-22(40)15-28(34,35)36)20-10-21(30)13-23(11-20)42-29(37,38)26(32)33/h3-13,17,22,26,39-40H,14-16H2,1-2H3/t22-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178700 (CHEMBL3814418) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC[C@H](O)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C28H26F9NO3/c1-16(2)40-23-12-18(8-9-22(23)30)26(14-17-6-4-3-5-7-17,38-15-24(39)27(33,34)35)19-10-20(29)13-21(11-19)41-28(36,37)25(31)32/h3-13,16,24-25,38-39H,14-15H2,1-2H3/t24-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516398 (CHEMBL4457286) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC(=O)C(N)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C30H26F12N2O4/c1-15(2)47-22-12-17(8-9-21(22)32)26(14-16-6-4-3-5-7-16,18-10-19(31)13-20(11-18)48-28(35,36)25(33)34)44-24(45)23(43)27(46,29(37,38)39)30(40,41)42/h3-13,15,23,25,46H,14,43H2,1-2H3,(H,44,45)/t23?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM205027 (US9249096, 40) Show SMILES OC1=C(CN(Cc2ccccc2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H20Cl2N2O3/c22-17-9-8-14(11-18(17)23)7-4-10-24-20(27)16-13-25(21(28)19(16)26)12-15-5-2-1-3-6-15/h1-3,5-6,8-9,11,26H,4,7,10,12-13H2,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516406 (CHEMBL4469874) Show SMILES CC(C)(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC(=O)C(N)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C31H28F12N2O4/c1-26(2,3)49-22-13-17(9-10-21(22)33)27(15-16-7-5-4-6-8-16,18-11-19(32)14-20(12-18)48-29(36,37)25(34)35)45-24(46)23(44)28(47,30(38,39)40)31(41,42)43/h4-14,23,25,47H,15,44H2,1-3H3,(H,45,46)/t23?,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516405 (CHEMBL4552555) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NCC(O)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C30H27F12NO4/c1-16(2)46-23-12-18(8-9-22(23)32)26(14-17-6-4-3-5-7-17,43-15-24(44)27(45,29(37,38)39)30(40,41)42)19-10-20(31)13-21(11-19)47-28(35,36)25(33)34/h3-13,16,24-25,43-45H,14-15H2,1-2H3/t24?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458638 (CHEMBL4203395) Show SMILES OC1=C(CN(CCOc2ccccc2)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C22H22Cl2N2O4/c23-18-9-8-15(13-19(18)24)5-4-10-25-21(28)17-14-26(22(29)20(17)27)11-12-30-16-6-2-1-3-7-16/h1-3,6-9,13,27H,4-5,10-12,14H2,(H,25,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516400 (CHEMBL4439856) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC(=O)C(N)C(O)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C29H27F9N2O4/c1-15(2)43-22-12-17(8-9-21(22)31)27(14-16-6-4-3-5-7-16,40-25(42)23(39)24(41)28(34,35)36)18-10-19(30)13-20(11-18)44-29(37,38)26(32)33/h3-13,15,23-24,26,41H,14,39H2,1-2H3,(H,40,42)/t23?,24?,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178691 (CHEMBL3814359) Show SMILES OC(CN[C@@](Cc1ccccc1)(c1cc(F)cc(c1)C(F)(F)F)c1ccc(Cl)cn1)CC(F)(F)F |r| Show InChI InChI=1S/C24H20ClF7N2O/c25-18-6-7-21(33-13-18)22(11-15-4-2-1-3-5-15,34-14-20(35)12-23(27,28)29)16-8-17(24(30,31)32)10-19(26)9-16/h1-10,13,20,34-35H,11-12,14H2/t20?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458637 (CHEMBL4210998) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NC)C1=O |t:19| Show InChI InChI=1S/C17H21Cl2N3O2/c1-3-22-10-12(15(20-2)17(22)24)16(23)21-8-4-5-11-6-7-13(18)14(19)9-11/h6-7,9,20H,3-5,8,10H2,1-2H3,(H,21,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516402 (CHEMBL4473304) Show SMILES NC(C(=O)N[C@](Cc1ccccc1)(c1ccc(F)cc1)c1cc(F)cc(c1)C(F)(F)F)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C26H19F11N2O2/c27-18-8-6-15(7-9-18)22(13-14-4-2-1-3-5-14,16-10-17(24(29,30)31)12-19(28)11-16)39-21(40)20(38)23(41,25(32,33)34)26(35,36)37/h1-12,20,41H,13,38H2,(H,39,40)/t20?,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50312718 (CHEMBL479527 | torcetrapib) Show SMILES CCOC(=O)N1[C@H](CC)C[C@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)C(=O)OC)c2cc(ccc12)C(F)(F)F |r| Show InChI InChI=1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27,28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30,31)32)10-17(9-14)26(33,34)35/h6-11,18,21H,4-5,12-13H2,1-3H3/t18-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178697 (CHEMBL3813777) Show SMILES O[C@H](CN[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C24H19ClF8N2O2/c25-16-6-7-19(34-12-16)22(11-14-4-2-1-3-5-14,35-13-20(36)23(29,30)31)15-8-17(26)10-18(9-15)37-24(32,33)21(27)28/h1-10,12,20-21,35-36H,11,13H2/t20-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50458647 (CHEMBL4212095) Show SMILES Cn1ccc(C(=O)NCCCc2ccc(Cl)c(Cl)c2)c(O)c1=O Show InChI InChI=1S/C16H16Cl2N2O3/c1-20-8-6-11(14(21)16(20)23)15(22)19-7-2-3-10-4-5-12(17)13(18)9-10/h4-6,8-9,21H,2-3,7H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human HL expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followed by substrate a...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506741 (CHEMBL4513722) Show SMILES Nc1c([nH]c(=O)[nH]c1=O)C(=O)N[C@@H]1CCc2cc(OCc3ccccc3)ccc12 |r| Show InChI InChI=1S/C21H20N4O4/c22-17-18(24-21(28)25-19(17)26)20(27)23-16-9-6-13-10-14(7-8-15(13)16)29-11-12-4-2-1-3-5-12/h1-5,7-8,10,16H,6,9,11,22H2,(H,23,27)(H2,24,25,26,28)/t16-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458645 (CHEMBL4215063) Show SMILES OC1=C(CN(CCCN2CCCC2=O)C1=O)C(=O)NCCCc1ccc(Cl)c(Cl)c1 |t:1| Show InChI InChI=1S/C21H25Cl2N3O4/c22-16-7-6-14(12-17(16)23)4-1-8-24-20(29)15-13-26(21(30)19(15)28)11-3-10-25-9-2-5-18(25)27/h6-7,12,28H,1-5,8-11,13H2,(H,24,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458642 (CHEMBL4218352) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCOC(C)C)C1=O |t:19| Show InChI InChI=1S/C21H29Cl2N3O3/c1-4-26-13-16(19(21(26)28)24-10-11-29-14(2)3)20(27)25-9-5-6-15-7-8-17(22)18(23)12-15/h7-8,12,14,24H,4-6,9-11,13H2,1-3H3,(H,25,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506738 (CHEMBL4558644) Show SMILES Nc1c([nH]c(=O)[nH]c1=O)C(=O)N[C@H]1CC[C@H](CC1)c1ccc(OCc2ccccc2)cc1 |r,wU:12.12,15.19,(34.47,-21.76,;34.48,-23.3,;33.15,-24.08,;33.16,-25.62,;34.48,-26.38,;34.48,-27.92,;35.82,-25.62,;35.82,-24.08,;37.15,-23.3,;31.82,-23.32,;31.81,-21.78,;30.49,-24.09,;29.15,-23.33,;27.82,-24.11,;26.49,-23.33,;26.49,-21.79,;27.82,-21.03,;29.15,-21.79,;25.16,-21.03,;25.17,-19.49,;23.83,-18.71,;22.5,-19.49,;21.16,-18.72,;21.16,-17.18,;19.83,-16.41,;19.83,-14.88,;18.5,-14.1,;17.17,-14.88,;17.17,-16.43,;18.51,-17.18,;22.5,-21.04,;23.84,-21.79,)| Show InChI InChI=1S/C24H26N4O4/c25-20-21(27-24(31)28-22(20)29)23(30)26-18-10-6-16(7-11-18)17-8-12-19(13-9-17)32-14-15-4-2-1-3-5-15/h1-5,8-9,12-13,16,18H,6-7,10-11,14,25H2,(H,26,30)(H2,27,28,29,31)/t16-,18+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178692 (CHEMBL3814646) Show SMILES O[C@H](CN[C@@](Cc1ccccc1)(c1cc(F)cc(c1)C(F)(F)F)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C23H18ClF7N2O/c24-17-6-7-19(32-12-17)21(11-14-4-2-1-3-5-14,33-13-20(34)23(29,30)31)15-8-16(22(26,27)28)10-18(25)9-15/h1-10,12,20,33-34H,11,13H2/t20-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458636 (CHEMBL4206624) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCCN2CCCCC2)C1=O |t:19| Show InChI InChI=1S/C24H34Cl2N4O2/c1-2-30-17-19(22(24(30)32)27-12-7-15-29-13-4-3-5-14-29)23(31)28-11-6-8-18-9-10-20(25)21(26)16-18/h9-10,16,27H,2-8,11-15,17H2,1H3,(H,28,31)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516408 (CHEMBL4468692) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NCC(N)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C30H28F12N2O3/c1-16(2)46-23-12-18(8-9-22(23)32)26(14-17-6-4-3-5-7-17,44-15-24(43)27(45,29(37,38)39)30(40,41)42)19-10-20(31)13-21(11-19)47-28(35,36)25(33)34/h3-13,16,24-25,44-45H,14-15,43H2,1-2H3/t24?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506731 (CHEMBL4439500) Show SMILES Oc1c([nH]c(=O)[nH]c1=O)C(=O)N[C@H]1CC[C@H](CC1)c1ccccc1 |r,wU:12.12,15.19,(30.37,-45.89,;30.37,-47.43,;29.05,-48.2,;29.05,-49.74,;30.38,-50.51,;30.38,-52.05,;31.71,-49.74,;31.71,-48.2,;33.05,-47.43,;27.71,-47.44,;27.7,-45.9,;26.38,-48.21,;25.05,-47.45,;23.72,-48.23,;22.38,-47.46,;22.38,-45.91,;23.72,-45.14,;25.05,-45.91,;21.05,-45.15,;21.05,-43.6,;19.72,-42.84,;18.38,-43.6,;18.39,-45.15,;19.72,-45.92,)| Show InChI InChI=1S/C17H19N3O4/c21-14-13(19-17(24)20-16(14)23)15(22)18-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-5,11-12,21H,6-9H2,(H,18,22)(H2,19,20,23,24)/t11-,12+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458644 (CHEMBL4214459) Show SMILES CN1C(CC(C)(C)C)C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:23| Show InChI InChI=1S/C20H26Cl2N2O3/c1-20(2,3)11-15-16(17(25)19(27)24(15)4)18(26)23-9-5-6-12-7-8-13(21)14(22)10-12/h7-8,10,15,25H,5-6,9,11H2,1-4H3,(H,23,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458646 (CHEMBL4207746) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:19| Show InChI InChI=1S/C16H18Cl2N2O3/c1-2-20-9-11(14(21)16(20)23)15(22)19-7-3-4-10-5-6-12(17)13(18)8-10/h5-6,8,21H,2-4,7,9H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516401 (CHEMBL4475826) Show SMILES OC(C(=O)N[C@@](Cc1ccccc1)(c1cc(F)cc(c1)C(F)(F)F)c1ccc(Cl)cn1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C25H17ClF10N2O3/c26-16-6-7-18(37-12-16)21(11-13-4-2-1-3-5-13,14-8-15(23(28,29)30)10-17(27)9-14)38-20(40)19(39)22(41,24(31,32)33)25(34,35)36/h1-10,12,19,39,41H,11H2,(H,38,40)/t19?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458639 (CHEMBL4207216) Show SMILES CN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:18| Show InChI InChI=1S/C15H16Cl2N2O3/c1-19-8-10(13(20)15(19)22)14(21)18-6-2-3-9-4-5-11(16)12(17)7-9/h4-5,7,20H,2-3,6,8H2,1H3,(H,18,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458640 (CHEMBL4203934) Show SMILES CCN1CC(C(=O)NC(C)CCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:20| Show InChI InChI=1S/C17H20Cl2N2O3/c1-3-21-9-12(15(22)17(21)24)16(23)20-10(2)4-5-11-6-7-13(18)14(19)8-11/h6-8,10,22H,3-5,9H2,1-2H3,(H,20,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178701 (CHEMBL3814374) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC[C@H](O)CC(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C29H28F9NO3/c1-17(2)41-25-12-19(8-9-24(25)31)27(14-18-6-4-3-5-7-18,39-16-22(40)15-28(34,35)36)20-10-21(30)13-23(11-20)42-29(37,38)26(32)33/h3-13,17,22,26,39-40H,14-16H2,1-2H3/t22-,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to LDL/VLDL				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506735 (CHEMBL4583457) Show SMILES Nc1c([nH]c(=O)[nH]c1=O)C(=O)N[C@@H]1CCCc2c(OCc3ccccc3)cccc12 |r| Show InChI InChI=1S/C22H22N4O4/c23-18-19(25-22(29)26-20(18)27)21(28)24-16-10-4-9-15-14(16)8-5-11-17(15)30-12-13-6-2-1-3-7-13/h1-3,5-8,11,16H,4,9-10,12,23H2,(H,24,28)(H2,25,26,27,29)/t16-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506734 (CHEMBL4586520) Show SMILES Nc1c([nH]c(=O)[nH]c1=O)C(=O)N[C@@H]1CC[C@H](c2ccccc2)c2ccccc12 |r| Show InChI InChI=1S/C21H20N4O3/c22-17-18(24-21(28)25-19(17)26)20(27)23-16-11-10-13(12-6-2-1-3-7-12)14-8-4-5-9-15(14)16/h1-9,13,16H,10-11,22H2,(H,23,27)(H2,24,25,26,28)/t13-,16-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178693 (CHEMBL3814330) Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)c1ccc(F)c(c1)C(F)(F)F)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C28H17ClF8N2O/c29-20-7-9-24(38-15-20)26(14-16-4-2-1-3-5-16,18-11-19(27(32,33)34)13-21(30)12-18)39-25(40)17-6-8-23(31)22(10-17)28(35,36)37/h1-13,15H,14H2,(H,39,40)/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to biotinylated LDL by scintillation pro...				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516399 (CHEMBL4448253) Show SMILES NC(C(=O)N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C26H19ClF11N3O3/c27-15-6-7-18(40-12-15)22(11-13-4-2-1-3-5-13,14-8-16(28)10-17(9-14)44-24(31,32)21(29)30)41-20(42)19(39)23(43,25(33,34)35)26(36,37)38/h1-10,12,19,21,43H,11,39H2,(H,41,42)/t19?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516399 (CHEMBL4448253) Show SMILES NC(C(=O)N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C26H19ClF11N3O3/c27-15-6-7-18(40-12-15)22(11-13-4-2-1-3-5-13,14-8-16(28)10-17(9-14)44-24(31,32)21(29)30)41-20(42)19(39)23(43,25(33,34)35)26(36,37)38/h1-10,12,19,21,43H,11,39H2,(H,41,42)/t19?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50178699 (CHEMBL3813836) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC[C@@H](O)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C28H26F9NO3/c1-16(2)40-23-12-18(8-9-22(23)30)26(14-17-6-4-3-5-7-17,38-15-24(39)27(33,34)35)19-10-20(29)13-21(11-19)41-28(36,37)25(31)32/h3-13,16,24-25,38-39H,14-15H2,1-2H3/t24-,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma assessed as reduction in [3H]cholesteryl ester transfer from [3H]CE-HDL to LDL/VLDL				Bioorg Med Chem Lett 26: 3278-3281 (2016) Article DOI: 10.1016/j.bmcl.2016.05.058 BindingDB Entry DOI: 10.7270/Q2TQ63FN
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516398 (CHEMBL4457286) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC(=O)C(N)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C30H26F12N2O4/c1-15(2)47-22-12-17(8-9-21(22)32)26(14-16-6-4-3-5-7-16,18-10-19(31)13-20(11-18)48-28(35,36)25(33)34)44-24(45)23(43)27(46,29(37,38)39)30(40,41)42/h3-13,15,23,25,46H,14,43H2,1-2H3,(H,44,45)/t23?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma assessed as reduction in [3H]-CE/HDL transfer incubated for 2.5 hrs by topcount scintillation counting assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516405 (CHEMBL4552555) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NCC(O)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C30H27F12NO4/c1-16(2)46-23-12-18(8-9-22(23)32)26(14-17-6-4-3-5-7-17,43-15-24(44)27(45,29(37,38)39)30(40,41)42)19-10-20(31)13-21(11-19)47-28(35,36)25(33)34/h3-13,16,24-25,43-45H,14-15H2,1-2H3/t24?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma assessed as reduction in [3H]-CE/HDL transfer incubated for 2.5 hrs by topcount scintillation counting assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458650 (CHEMBL4212990) Show SMILES CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(NCCc2ccncc2)C1=O |t:19| Show InChI InChI=1S/C23H26Cl2N4O2/c1-2-29-15-18(21(23(29)31)27-13-9-16-7-11-26-12-8-16)22(30)28-10-3-4-17-5-6-19(24)20(25)14-17/h5-8,11-12,14,27H,2-4,9-10,13,15H2,1H3,(H,28,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458643 (CHEMBL4206109) Show SMILES CN1C(C(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O)c1ccccc1Cl |t:18| Show InChI InChI=1S/C21H19Cl3N2O3/c1-26-18(13-6-2-3-7-14(13)22)17(19(27)21(26)29)20(28)25-10-4-5-12-8-9-15(23)16(24)11-12/h2-3,6-9,11,18,27H,4-5,10H2,1H3,(H,25,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506737 (CHEMBL4555254) Show SMILES CC(C)Cn1c(=O)[nH]c(C(=O)N[C@H]2CC[C@H](CC2)c2ccccc2)c(O)c1=O |r,wU:12.11,15.18,(50.18,-52.33,;48.85,-51.57,;47.52,-52.33,;48.85,-50.03,;47.52,-49.27,;46.18,-50.04,;46.18,-51.58,;44.85,-49.27,;44.85,-47.73,;43.51,-46.97,;43.5,-45.43,;42.18,-47.74,;40.84,-46.98,;39.52,-47.75,;38.18,-46.98,;38.18,-45.44,;39.51,-44.67,;40.84,-45.44,;36.84,-44.67,;36.85,-43.13,;35.51,-42.36,;34.18,-43.13,;34.18,-44.68,;35.52,-45.44,;46.18,-46.95,;46.17,-45.41,;47.51,-47.72,;48.85,-46.96,)| Show InChI InChI=1S/C21H27N3O4/c1-13(2)12-24-20(27)18(25)17(23-21(24)28)19(26)22-16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-7,13,15-16,25H,8-12H2,1-2H3,(H,22,26)(H,23,28)/t15-,16+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50458647 (CHEMBL4212095) Show SMILES Cn1ccc(C(=O)NCCCc2ccc(Cl)c(Cl)c2)c(O)c1=O Show InChI InChI=1S/C16H16Cl2N2O3/c1-20-8-6-11(14(21)16(20)23)15(22)19-7-2-3-10-4-5-12(17)13(18)9-10/h4-6,8-9,21H,2-3,7H2,1H3,(H,19,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of endothelial lipase in human HT1080 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by substrat...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516410 (CHEMBL4574163) Show SMILES NC(C(=O)N[C@](Cc1ccccc1)(c1ccc(F)c(OC2CC2)c1)c1cc(F)cc(OC(F)(F)C(F)F)c1)C(O)(C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C30H24F12N2O4/c31-18-10-17(11-20(13-18)48-28(35,36)25(33)34)26(14-15-4-2-1-3-5-15,16-6-9-21(32)22(12-16)47-19-7-8-19)44-24(45)23(43)27(46,29(37,38)39)30(40,41)42/h1-6,9-13,19,23,25,46H,7-8,14,43H2,(H,44,45)/t23?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma assessed as reduction in [3H]-CE/HDL transfer incubated for 2.5 hrs by topcount scintillation counting assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50458639 (CHEMBL4207216) Show SMILES CN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:18| Show InChI InChI=1S/C15H16Cl2N2O3/c1-19-8-10(13(20)15(19)22)14(21)18-6-2-3-9-4-5-11(16)12(17)7-9/h4-5,7,20H,2-3,6,8H2,1H3,(H,18,21)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human HL expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followed by substrate a...				ACS Med Chem Lett 9: 673-678 (2018) Article DOI: 10.1021/acsmedchemlett.8b00138 BindingDB Entry DOI: 10.7270/Q2JS9T2R
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506742 (CHEMBL4589512) Show SMILES OCCn1c(=O)[nH]c(C(=O)N[C@H]2CC[C@H](CC2)c2ccccc2)c(O)c1=O |r,wU:11.10,14.17,(85.09,-51.38,;83.76,-50.62,;83.76,-49.08,;82.43,-48.32,;81.09,-49.09,;81.09,-50.63,;79.76,-48.32,;79.76,-46.78,;78.42,-46.02,;78.42,-44.48,;77.09,-46.79,;75.76,-46.03,;74.43,-46.8,;73.09,-46.03,;73.09,-44.49,;74.43,-43.72,;75.76,-44.49,;71.76,-43.72,;71.76,-42.18,;70.43,-41.41,;69.09,-42.18,;69.09,-43.73,;70.43,-44.5,;81.09,-46.01,;81.08,-44.46,;82.43,-46.78,;83.76,-46.01,)| Show InChI InChI=1S/C19H23N3O5/c23-11-10-22-18(26)16(24)15(21-19(22)27)17(25)20-14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-5,13-14,23-24H,6-11H2,(H,20,25)(H,21,27)/t13-,14+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50506732 (CHEMBL4592858) Show SMILES CCN1CC(C(=O)N[C@H]2CC[C@H](CC2)c2ccccc2)=C(O)C1=O |r,wU:8.7,11.14,t:21,(33.21,-13.77,;34.11,-12.51,;33.48,-11.11,;31.97,-10.8,;31.8,-9.27,;30.46,-8.5,;30.46,-6.96,;29.13,-9.28,;27.8,-8.51,;26.47,-9.29,;25.14,-8.52,;25.13,-6.98,;26.47,-6.21,;27.8,-6.97,;23.8,-6.21,;23.81,-4.67,;22.47,-3.9,;21.14,-4.67,;21.14,-6.21,;22.48,-6.98,;33.21,-8.64,;33.52,-7.13,;34.24,-9.77,;35.78,-9.61,)| Show InChI InChI=1S/C19H24N2O3/c1-2-21-12-16(17(22)19(21)24)18(23)20-15-10-8-14(9-11-15)13-6-4-3-5-7-13/h3-7,14-15,22H,2,8-12H2,1H3,(H,20,23)/t14-,15+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase expressed in African green monkey COS7 cells using HDL as substrate pretreated for 10 mins followe...				Bioorg Med Chem Lett 28: 3721-3725 (2018) Article DOI: 10.1016/j.bmcl.2018.10.022 BindingDB Entry DOI: 10.7270/Q2JS9TQ8
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50516404 (CHEMBL4439823) Show SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NC(=O)C(O)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1 |r| Show InChI InChI=1S/C30H25F12NO5/c1-15(2)47-22-12-17(8-9-21(22)32)26(14-16-6-4-3-5-7-16,18-10-19(31)13-20(11-18)48-28(35,36)25(33)34)43-24(45)23(44)27(46,29(37,38)39)30(40,41)42/h3-13,15,23,25,44,46H,14H2,1-2H3,(H,43,45)/t23?,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma assessed as reduction in [3H]-CE/HDL transfer incubated for 2.5 hrs by topcount scintillation counting assay				ACS Med Chem Lett 10: 911-916 (2019) Article DOI: 10.1021/acsmedchemlett.9b00086 BindingDB Entry DOI: 10.7270/Q2TX3JQJ
					More data for this Ligand-Target Pair

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