Compile Data Set for Download or QSAR

Found 136 hits with Last Name = 'chu' and Initial = 'ck'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17468 (1,2,3-triazole analogue, 24 | 5-(3,4-dibromophenyl...) Show SMILES Brc1ccc(cc1Br)-c1c[nH]nn1 Show InChI InChI=1S/C8H5Br2N3/c9-6-2-1-5(3-7(6)10)8-4-11-13-12-8/h1-4H,(H,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1	-50.9	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17461 (1,2,3-triazole analogue, 17 | 5-(4-iodophenyl)-1H-...) Show SMILES Ic1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6IN3/c9-7-3-1-6(2-4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	1	-50.9	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17474 (1,2,3-triazole analogue, 30 | 4-methyl-2-(1H-1,2,3...) Show SMILES Cc1ccnc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H8N4/c1-6-2-3-9-7(4-6)8-5-10-12-11-8/h2-5H,1H3,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	-48.2	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17460 (1,2,3-triazole analogue, 16 | 5-(4-bromophenyl)-1H...) Show SMILES Brc1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-6(2-4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	3	-48.2	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	4	-47.5	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17459 (1,2,3-triazole analogue, 15 | 5-(4-chlorophenyl)-1...) Show SMILES Clc1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6ClN3/c9-7-3-1-6(2-4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	6	-46.5	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17473 (1,2,3-triazole analogue, 29 | 3-methyl-2-(1H-1,2,3...) Show SMILES Cc1cccnc1-c1c[nH]nn1 Show InChI InChI=1S/C8H8N4/c1-6-3-2-4-9-8(6)7-5-10-12-11-7/h2-5H,1H3,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6	-46.5	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17475 (1,2,3-triazole analogue, 31 | 5-methyl-2-(1H-1,2,3...) Show SMILES Cc1ccc(nc1)-c1c[nH]nn1 Show InChI InChI=1S/C8H8N4/c1-6-2-3-7(9-4-6)8-5-10-12-11-8/h2-5H,1H3,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8	-45.7	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17469 (1,2,3-triazole analogue, 25 | 5-(1-benzofuran-2-yl...) Show SMILES c1[nH]nnc1-c1cc2ccccc2o1 Show InChI InChI=1S/C10H7N3O/c1-2-4-9-7(3-1)5-10(14-9)8-6-11-13-12-8/h1-6H,(H,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	-44.6	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17447 (1,2,3-triazole analogue, 3 | 5-(4-methylphenyl)-1H...) Show SMILES Cc1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C9H9N3/c1-7-2-4-8(5-3-7)9-6-10-12-11-9/h2-6H,1H3,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	15	-44.2	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17466 (1,2,3-triazole analogue, 22 | 5-(3-iodophenyl)-1H-...) Show SMILES Ic1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6IN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	-44.0	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17462 (1,2,3-triazole analogue, 18 | 5-(3-methylphenyl)-1...) Show SMILES Cc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C9H9N3/c1-7-3-2-4-8(5-7)9-6-10-12-11-9/h2-6H,1H3,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	18	-43.8	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17465 (1,2,3-triazole analogue, 21 | N-benzyl-3-(1H-1,2,3...) Show SMILES C(Nc1cccc(c1)-c1c[nH]nn1)c1ccccc1 Show InChI InChI=1S/C15H14N4/c1-2-5-12(6-3-1)10-16-14-8-4-7-13(9-14)15-11-17-19-18-15/h1-9,11,16H,10H2,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	29	-42.6	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17455 (1,2,3-triazole analogue, 11 | 5-(4-ethylphenyl)-1H...) Show SMILES CCc1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C10H11N3/c1-2-8-3-5-9(6-4-8)10-7-11-13-12-10/h3-7H,2H2,1H3,(H,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	30	-42.5	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17470 (1,2,3-triazole analogue, 26 | 2-(1H-1,2,3-triazol-...) Show SMILES c1[nH]nnc1-c1ccccn1 Show InChI InChI=1S/C7H6N4/c1-2-4-8-6(3-1)7-5-9-11-10-7/h1-5H,(H,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	41	-41.7	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17449 (1,2,3-triazole analogue, 5 | 1H,4H-indeno[1,2-d][1...) Show SMILES c1c2ccccc2c2n[nH][nH]c12 Show InChI InChI=1S/C9H7N3/c1-2-4-7-6(3-1)5-8-9(7)11-12-10-8/h1-5,10,12H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	-41.2	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17476 (1,2,3-triazole analogue, 32 | 2-methyl-6-(1H-1,2,3...) Show SMILES Cc1cccc(n1)-c1c[nH]nn1 Show InChI InChI=1S/C8H8N4/c1-6-3-2-4-7(10-6)8-5-9-12-11-8/h2-5H,1H3,(H,9,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	52	-41.2	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17448 (1,2,3-triazole analogue, 4 | 5-phenyl-1H-1,2,3-tri...) Show SMILES c1[nH]nnc1-c1ccccc1 Show InChI InChI=1S/C8H7N3/c1-2-4-7(5-3-1)8-6-9-11-10-8/h1-6H,(H,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	70	-40.4	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17452 (1,2,3-triazole analogue, 8 | 5-(2-methylphenyl)-1H...) Show SMILES Cc1ccccc1-c1c[nH]nn1 Show InChI InChI=1S/C9H9N3/c1-7-4-2-3-5-8(7)9-6-10-12-11-9/h2-6H,1H3,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	112	-39.3	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17453 (1,2,3-triazole analogue, 9 | 5-(2-methoxyphenyl)-1...) Show SMILES COc1ccccc1-c1c[nH]nn1 Show InChI InChI=1S/C9H9N3O/c1-13-9-5-3-2-4-7(9)8-6-10-12-11-8/h2-6H,1H3,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	150	-38.6	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17471 (1,2,3-triazole analogue, 27 | 3-(1H-1,2,3-triazol-...) Show SMILES c1[nH]nnc1-c1cccnc1 Show InChI InChI=1S/C7H6N4/c1-2-6(4-8-3-1)7-5-9-11-10-7/h1-5H,(H,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	260	-37.2	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17464 (1,2,3-triazole analogue, 20 | 3-(1H-1,2,3-triazol-...) Show SMILES Nc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H8N4/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,9H2,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	280	-37.0	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17450 (4-(4-methylphenyl)-1H-pyrazole | pyrazole analogue...) Show SMILES Cc1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C10H10N2/c1-8-2-4-9(5-3-8)10-6-11-12-7-10/h2-7H,1H3,(H,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	280	-37.0	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17463 (1,2,3-triazole analogue, 19 | 3-(1H-1,2,3-triazol-...) Show SMILES Oc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H7N3O/c12-7-3-1-2-6(4-7)8-5-9-11-10-8/h1-5,12H,(H,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	300	-36.9	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17458 (1,2,3-triazole analogue, 14 | 4-(1H-1,2,3-triazol-...) Show SMILES Nc1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C8H8N4/c9-7-3-1-6(2-4-7)8-5-10-12-11-8/h1-5H,9H2,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	337	-36.6	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17472 (1,2,3-triazole analogue, 28 | 4-(1H-1,2,3-triazol-...) Show SMILES c1[nH]nnc1-c1ccncc1 Show InChI InChI=1S/C7H6N4/c1-3-8-4-2-6(1)7-5-9-11-10-7/h1-5H,(H,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	>1.00E+3	>-33.9	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17454 (1,2,3-triazole analogue, 10 | 5-(2-phenylphenyl)-1...) Show SMILES c1[nH]nnc1-c1ccccc1-c1ccccc1 Show InChI InChI=1S/C14H11N3/c1-2-6-11(7-3-1)12-8-4-5-9-13(12)14-10-15-17-16-14/h1-10H,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	>1.00E+3	>-33.9	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17457 (1,2,3-triazole analogue, 13 | 4-(1H-1,2,3-triazol-...) Show SMILES Oc1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C8H7N3O/c12-7-3-1-6(2-4-7)8-5-9-11-10-8/h1-5,12H,(H,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	>-33.9	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17456 (1,2,3-triazole analogue, 12 | 5-(4-propylphenyl)-1...) Show SMILES CCCc1ccc(cc1)-c1c[nH]nn1 Show InChI InChI=1S/C11H13N3/c1-2-3-9-4-6-10(7-5-9)11-8-12-14-13-11/h4-8H,2-3H2,1H3,(H,12,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	>-33.9	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252013 (4-[(4-Cyanobenzyl)thio]-7-(beta-D-ribofuranosyl)-7...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(SCc3ccc(cc3)C#N)ncnc12 |r| Show InChI InChI=1S/C19H18N4O4S/c20-7-11-1-3-12(4-2-11)9-28-18-13-5-6-23(17(13)21-10-22-18)19-16(26)15(25)14(8-24)27-19/h1-6,10,14-16,19,24-26H,8-9H2/t14-,15-,16-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252067 (4-[(4-Methoxybenzyl)thio]-7-(beta-D-ribofuranosyl)...) Show SMILES COc1ccc(CSc2ncnc3n(ccc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C19H21N3O5S/c1-26-12-4-2-11(3-5-12)9-28-18-13-6-7-22(17(13)20-10-21-18)19-16(25)15(24)14(8-23)27-19/h2-7,10,14-16,19,23-25H,8-9H2,1H3/t14-,15-,16-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252014 (4-[(4-Methoxycarbonylbenzyl)thio]-7-(beta-D-ribofu...) Show SMILES COC(=O)c1ccc(CSc2ncnc3n(ccc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C20H21N3O6S/c1-28-20(27)12-4-2-11(3-5-12)9-30-18-13-6-7-23(17(13)21-10-22-18)19-16(26)15(25)14(8-24)29-19/h2-7,10,14-16,19,24-26H,8-9H2,1H3/t14-,15-,16-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252116 (4-[(2-Chloro-6-fluorobenzyl)thio]-7-(beta-D-ribofu...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(SCc3c(F)cccc3Cl)ncnc12 |r| Show InChI InChI=1S/C18H17ClFN3O4S/c19-11-2-1-3-12(20)10(11)7-28-17-9-4-5-23(16(9)21-8-22-17)18-15(26)14(25)13(6-24)27-18/h1-5,8,13-15,18,24-26H,6-7H2/t13-,14-,15-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316806 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES Cc1ccc(CSc2ncnc3n(cnc23)[C@@H]2C[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C19H22N4O3S/c1-11-2-4-12(5-3-11)8-27-19-15-18(20-9-21-19)23(10-22-15)14-6-13(7-24)16(25)17(14)26/h2-5,9-10,13-14,16-17,24-26H,6-8H2,1H3/t13-,14-,16-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50251864 (4-[(3-Methylbenzyl)thio]-7-(beta-D-ribofuranosyl)-...) Show SMILES Cc1cccc(CSc2ncnc3n(ccc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1 |r| Show InChI InChI=1S/C19H21N3O4S/c1-11-3-2-4-12(7-11)9-27-18-13-5-6-22(17(13)20-10-21-18)19-16(25)15(24)14(8-23)26-19/h2-7,10,14-16,19,23-25H,8-9H2,1H3/t14-,15-,16-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM14487 ((2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenosine kinase (Toxoplasma gondii)	BDBM50251909 (4-[(4-Chlorobenzyl)thio]-7-(beta-D-ribofuranosyl)-...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(SCc3ccc(Cl)cc3)ncnc12 |r| Show InChI InChI=1S/C18H18ClN3O4S/c19-11-3-1-10(2-4-11)8-27-17-12-5-6-22(16(12)20-9-21-17)18-15(25)14(24)13(7-23)26-18/h1-6,9,13-15,18,23-25H,7-8H2/t13-,14-,15-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50240561 ((2R,3R,4S,5R)-2-(6-(benzylthio)-9H-purin-9-yl)-5-(...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3ccccc3)ncnc12 |r| Show InChI InChI=1S/C17H18N4O4S/c22-6-11-13(23)14(24)17(25-11)21-9-20-12-15(21)18-8-19-16(12)26-7-10-4-2-1-3-5-10/h1-5,8-9,11,13-14,17,22-24H,6-7H2/t11-,13-,14-,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316801 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3ccc(Cl)cc3)ncnc12 |r| Show InChI InChI=1S/C18H19ClN4O3S/c19-12-3-1-10(2-4-12)7-27-18-14-17(20-8-21-18)23(9-22-14)13-5-11(6-24)15(25)16(13)26/h1-4,8-9,11,13,15-16,24-26H,5-7H2/t11-,13-,15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252068 (4-[(2,4-Difluorobenzyl)thio]-7-(beta-D-ribofuranos...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(SCc3ccc(F)cc3F)ncnc12 |r| Show InChI InChI=1S/C18H17F2N3O4S/c19-10-2-1-9(12(20)5-10)7-28-17-11-3-4-23(16(11)21-8-22-17)18-15(26)14(25)13(6-24)27-18/h1-5,8,13-15,18,24-26H,6-7H2/t13-,14-,15-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316811 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3ccc(Cl)c(Cl)c3)ncnc12 |r| Show InChI InChI=1S/C18H18Cl2N4O3S/c19-11-2-1-9(3-12(11)20)6-28-18-14-17(21-7-22-18)24(8-23-14)13-4-10(5-25)15(26)16(13)27/h1-3,7-8,10,13,15-16,25-27H,4-6H2/t10-,13-,15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252015 (4-[(4-Methylbenzyl)thio]-7-(beta-D-ribofuranosyl)-...) Show SMILES Cc1ccc(CSc2ncnc3n(ccc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C19H21N3O4S/c1-11-2-4-12(5-3-11)9-27-18-13-6-7-22(17(13)20-10-21-18)19-16(25)15(24)14(8-23)26-19/h2-7,10,14-16,19,23-25H,8-9H2,1H3/t14-,15-,16-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316802 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3ccc(Br)cc3)ncnc12 |r| Show InChI InChI=1S/C18H19BrN4O3S/c19-12-3-1-10(2-4-12)7-27-18-14-17(20-8-21-18)23(9-22-14)13-5-11(6-24)15(25)16(13)26/h1-4,8-9,11,13,15-16,24-26H,5-7H2/t11-,13-,15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50251863 (4-[(3-Trifluoromethylbenzyl)thio]-7-(beta-D-ribofu...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(SCc3cccc(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C19H18F3N3O4S/c20-19(21,22)11-3-1-2-10(6-11)8-30-17-12-4-5-25(16(12)23-9-24-17)18-15(28)14(27)13(7-26)29-18/h1-6,9,13-15,18,26-28H,7-8H2/t13-,14-,15-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316798 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3cccc(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C19H19F3N4O3S/c20-19(21,22)12-3-1-2-10(4-12)7-30-18-14-17(23-8-24-18)26(9-25-14)13-5-11(6-27)15(28)16(13)29/h1-4,8-9,11,13,15-16,27-29H,5-7H2/t11-,13-,15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.22E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252064 (4-[(4-tert-Butylbenzyl)thio]-7-(beta-D-ribofuranos...) Show SMILES CC(C)(C)c1ccc(CSc2ncnc3n(ccc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C22H27N3O4S/c1-22(2,3)14-6-4-13(5-7-14)11-30-20-15-8-9-25(19(15)23-12-24-20)21-18(28)17(27)16(10-26)29-21/h4-9,12,16-18,21,26-28H,10-11H2,1-3H3/t16-,17-,18-,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316795 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3ccccc3Cl)ncnc12 |r| Show InChI InChI=1S/C18H19ClN4O3S/c19-12-4-2-1-3-10(12)7-27-18-14-17(20-8-21-18)23(9-22-14)13-5-11(6-24)15(25)16(13)26/h1-4,8-9,11,13,15-16,24-26H,5-7H2/t11-,13-,15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316796 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES Cc1ccccc1CSc1ncnc2n(cnc12)[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C19H22N4O3S/c1-11-4-2-3-5-12(11)8-27-19-15-18(20-9-21-19)23(10-22-15)14-6-13(7-24)16(25)17(14)26/h2-5,9-10,13-14,16-17,24-26H,6-8H2,1H3/t13-,14-,16-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.49E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50252114 (4-[(2,4-Dichlorobenzyl)thio]-7-(beta-D-ribofuranos...) Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(SCc3ccc(Cl)cc3Cl)ncnc12 |r| Show InChI InChI=1S/C18H17Cl2N3O4S/c19-10-2-1-9(12(20)5-10)7-28-17-11-3-4-23(16(11)21-8-22-17)18-15(26)14(25)13(6-24)27-18/h1-5,8,13-15,18,24-26H,6-7H2/t13-,14-,15-,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to purified Toxoplasma gondii adenosine kinase				J Med Chem 51: 3934-45 (2008) Article DOI: 10.1021/jm800201s BindingDB Entry DOI: 10.7270/Q2NK3DVP
					More data for this Ligand-Target Pair
Adenosine kinase (Toxoplasma gondii)	BDBM50316797 ((1'R,2'S,3'R,4'R)-1-[2,3-Dihydroxy-4-(hydroxymethy...) Show SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H]1O)n1cnc2c(SCc3cccc(c3)[N+]([O-])=O)ncnc12 |r| Show InChI InChI=1S/C18H19N5O5S/c24-6-11-5-13(16(26)15(11)25)22-9-21-14-17(22)19-8-20-18(14)29-7-10-2-1-3-12(4-10)23(27)28/h1-4,8-9,11,13,15-16,24-26H,5-7H2/t11-,13-,15-,16+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.66E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Georgia Curated by ChEMBL					Assay Description Binding affinity to Toxoplasma gondii adenosine kinase after 20 mins by radioactivity method				Bioorg Med Chem 18: 3403-12 (2010) Article DOI: 10.1016/j.bmc.2010.04.003 BindingDB Entry DOI: 10.7270/Q2WH2Q43
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 136 total )  |  Next  |  Last  >>

Jump to: