Compile Data Set for Download or QSAR

Found 30 hits with Last Name = 'cook' and Initial = 'ce'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.0540	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50222089 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-et...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(cc2)C(C)=O)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C31H35NO3/c1-5-28-32-31(19(3)35-28)15-14-27-25-12-10-22-16-23(34)11-13-24(22)29(25)26(17-30(27,31)4)21-8-6-20(7-9-21)18(2)33/h6-9,16,25-27H,3,5,10-15,17H2,1-2,4H3/t25-,26+,27-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222091 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15...) Show SMILES CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C30H33NO3/c1-17(32)20-5-7-21(8-6-20)26-16-29(4)27(13-14-30(29)18(2)34-19(3)31-30)25-11-9-22-15-23(33)10-12-24(22)28(25)26/h5-8,15,25-27H,2,9-14,16H2,1,3-4H3/t25-,26+,27-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222086 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C30H36N2O2/c1-18-30(31-19(2)34-18)15-14-27-25-12-8-21-16-23(33)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)32(4)5/h6-7,9-10,16,25-27H,1,8,11-15,17H2,2-5H3/t25-,26+,27-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222092 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(cc2)N(C)C)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C31H38N2O2/c1-6-28-32-31(19(2)35-28)16-15-27-25-13-9-21-17-23(34)12-14-24(21)29(25)26(18-30(27,31)3)20-7-10-22(11-8-20)33(4)5/h7-8,10-11,17,25-27H,2,6,9,12-16,18H2,1,3-5H3/t25-,26+,27-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222088 ((3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-m...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(OC)c(F)c2)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C30H34FNO3/c1-5-27-32-30(17(2)35-27)13-12-24-22-9-6-18-14-20(33)8-10-21(18)28(22)23(16-29(24,30)3)19-7-11-26(34-4)25(31)15-19/h7,11,14-15,22-24H,2,5-6,8-10,12-13,16H2,1,3-4H3/t22-,23+,24-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222087 ((3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyph...) Show SMILES COc1ccc(cc1F)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C29H32FNO3/c1-16-29(31-17(2)34-16)12-11-24-22-8-5-18-13-20(32)7-9-21(18)27(22)23(15-28(24,29)3)19-6-10-26(33-4)25(30)14-19/h6,10,13-14,22-24H,1,5,7-9,11-12,15H2,2-4H3/t22-,23+,24-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50364466 (CHEMBL1950695) Show SMILES CCc1nc2cc(ccc2o1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:29,36| Show InChI InChI=1S/C30H33NO3/c1-4-13-30(33)14-12-24-22-9-6-18-15-20(32)8-10-21(18)28(22)23(17-29(24,30)3)19-7-11-26-25(16-19)31-27(5-2)34-26/h7,11,15-16,22-24,33H,5-6,8-10,12,14,17H2,1-3H3/t22-,23+,24-,29-,30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of dexamethasone-induced transcription at GRE after 24 hrs ...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222085 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=COC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |c:19,t:28,35| Show InChI InChI=1S/C29H34N2O2/c1-18-29(30-17-33-18)14-13-26-24-11-7-20-15-22(32)10-12-23(20)27(24)25(16-28(26,29)2)19-5-8-21(9-6-19)31(3)4/h5-6,8-9,15,17,24-26H,1,7,10-14,16H2,2-4H3/t24-,25+,26-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222092 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(cc2)N(C)C)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C31H38N2O2/c1-6-28-32-31(19(2)35-28)16-15-27-25-13-9-21-17-23(34)12-14-24(21)29(25)26(18-30(27,31)3)20-7-10-22(11-8-20)33(4)5/h7-8,10-11,17,25-27H,2,6,9,12-16,18H2,1,3-5H3/t25-,26+,27-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50364465 (CHEMBL1950694) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2oc(C)nc2c1 |r,c:18,t:11| Show InChI InChI=1S/C29H31NO3/c1-4-12-29(32)13-11-24-22-8-5-18-14-20(31)7-9-21(18)27(22)23(16-28(24,29)3)19-6-10-26-25(15-19)30-17(2)33-26/h6,10,14-15,22-24,32H,5,7-9,11,13,16H2,1-3H3/t22-,23+,24-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of dexamethasone-induced transcription at GRE after 24 hrs ...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50364465 (CHEMBL1950694) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2oc(C)nc2c1 |r,c:18,t:11| Show InChI InChI=1S/C29H31NO3/c1-4-12-29(32)13-11-24-22-8-5-18-14-20(31)7-9-21(18)27(22)23(16-28(24,29)3)19-6-10-26-25(15-19)30-17(2)33-26/h6,10,14-15,22-24,32H,5,7-9,11,13,16H2,1-3H3/t22-,23+,24-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 2...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50364468 (CHEMBL1950698) Show SMILES CC#C[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2ocnc2c1)NC=O |r,c:17,t:10| Show InChI InChI=1S/C29H30N2O3/c1-3-11-29(31-16-32)12-10-24-22-7-4-18-13-20(33)6-8-21(18)27(22)23(15-28(24,29)2)19-5-9-26-25(14-19)30-17-34-26/h5,9,13-14,16-17,22-24H,4,6-8,10,12,15H2,1-2H3,(H,31,32)/t22-,23+,24-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 2...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50364464 (CHEMBL1950693) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2ocnc2c1 |r,c:18,t:11| Show InChI InChI=1S/C28H29NO3/c1-3-11-28(31)12-10-23-21-7-4-17-13-19(30)6-8-20(17)26(21)22(15-27(23,28)2)18-5-9-25-24(14-18)29-16-32-25/h5,9,13-14,16,21-23,31H,4,6-8,10,12,15H2,1-2H3/t21-,22+,23-,27-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of dexamethasone-induced transcription at GRE after 24 hrs ...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50364469 (CHEMBL1950696) Show SMILES CC#C[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2oc(nc2c1)C(F)(F)F)NC=O |r,c:17,t:10| Show InChI InChI=1S/C30H29F3N2O3/c1-3-11-29(34-16-36)12-10-23-21-7-4-17-13-19(37)6-8-20(17)26(21)22(15-28(23,29)2)18-5-9-25-24(14-18)35-27(38-25)30(31,32)33/h5,9,13-14,16,21-23H,4,6-8,10,12,15H2,1-2H3,(H,34,36)/t21-,22+,23-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 2...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50364468 (CHEMBL1950698) Show SMILES CC#C[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2ocnc2c1)NC=O |r,c:17,t:10| Show InChI InChI=1S/C29H30N2O3/c1-3-11-29(31-16-32)12-10-24-22-7-4-18-13-20(33)6-8-21(18)27(22)23(15-28(24,29)2)19-5-9-26-25(14-19)30-17-34-26/h5,9,13-14,16-17,22-24H,4,6-8,10,12,15H2,1-2H3,(H,31,32)/t22-,23+,24-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of dexamethasone-induced transcription at GRE after 24 hrs ...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50364467 (CHEMBL1950697) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2oc(nc2c1)C(F)(F)F |r,c:18,t:11| Show InChI InChI=1S/C29H28F3NO3/c1-3-11-28(35)12-10-22-20-7-4-16-13-18(34)6-8-19(16)25(20)21(15-27(22,28)2)17-5-9-24-23(14-17)33-26(36-24)29(30,31)32/h5,9,13-14,20-22,35H,4,6-8,10,12,15H2,1-2H3/t20-,21+,22-,27-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of dexamethasone-induced transcription at GRE after 24 hrs ...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50364466 (CHEMBL1950695) Show SMILES CCc1nc2cc(ccc2o1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:29,36| Show InChI InChI=1S/C30H33NO3/c1-4-13-30(33)14-12-24-22-9-6-18-15-20(32)8-10-21(18)28(22)23(17-29(24,30)3)19-7-11-26-25(16-19)31-27(5-2)34-26/h7,11,15-16,22-24,33H,5-6,8-10,12,14,17H2,1-3H3/t22-,23+,24-,29-,30-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 2...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222090 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...) Show SMILES CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=COC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |c:19,t:28,35| Show InChI InChI=1S/C29H31NO3/c1-17(31)19-4-6-20(7-5-19)25-15-28(3)26(12-13-29(28)18(2)33-16-30-29)24-10-8-21-14-22(32)9-11-23(21)27(24)25/h4-7,14,16,24-26H,2,8-13,15H2,1,3H3/t24-,25+,26-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222086 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C30H36N2O2/c1-18-30(31-19(2)34-18)15-14-27-25-12-8-21-16-23(33)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)32(4)5/h6-7,9-10,16,25-27H,1,8,11-15,17H2,2-5H3/t25-,26+,27-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50364467 (CHEMBL1950697) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2oc(nc2c1)C(F)(F)F |r,c:18,t:11| Show InChI InChI=1S/C29H28F3NO3/c1-3-11-28(35)12-10-22-20-7-4-16-13-18(34)6-8-19(16)25(20)21(15-27(22,28)2)17-5-9-24-23(14-17)33-26(36-24)29(30,31)32/h5,9,13-14,20-22,35H,4,6-8,10,12,15H2,1-2H3/t20-,21+,22-,27-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 2...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50364464 (CHEMBL1950693) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2ocnc2c1 |r,c:18,t:11| Show InChI InChI=1S/C28H29NO3/c1-3-11-28(31)12-10-23-21-7-4-17-13-19(30)6-8-20(17)26(21)22(15-27(23,28)2)18-5-9-25-24(14-18)29-16-32-25/h5,9,13-14,16,21-23,31H,4,6-8,10,12,15H2,1-2H3/t21-,22+,23-,27-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 2...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50364469 (CHEMBL1950696) Show SMILES CC#C[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc2oc(nc2c1)C(F)(F)F)NC=O |r,c:17,t:10| Show InChI InChI=1S/C30H29F3N2O3/c1-3-11-29(34-16-36)12-10-23-21-7-4-17-13-19(37)6-8-20(17)26(21)22(15-28(23,29)2)18-5-9-25-24(14-18)35-27(38-25)30(31,32)33/h5,9,13-14,16,21-23H,4,6-8,10,12,15H2,1-2H3,(H,34,36)/t21-,22+,23-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of dexamethasone-induced transcription at GRE after 24 hrs ...				Bioorg Med Chem Lett 22: 1705-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.110 BindingDB Entry DOI: 10.7270/Q2QF8TB2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222089 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-et...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(cc2)C(C)=O)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C31H35NO3/c1-5-28-32-31(19(3)35-28)15-14-27-25-12-10-22-16-23(34)11-13-24(22)29(25)26(17-30(27,31)4)21-8-6-20(7-9-21)18(2)33/h6-9,16,25-27H,3,5,10-15,17H2,1-2,4H3/t25-,26+,27-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222091 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15...) Show SMILES CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C30H33NO3/c1-17(32)20-5-7-21(8-6-20)26-16-29(4)27(13-14-30(29)18(2)34-19(3)31-30)25-11-9-22-15-23(33)10-12-24(22)28(25)26/h5-8,15,25-27H,2,9-14,16H2,1,3-4H3/t25-,26+,27-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222085 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=COC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |c:19,t:28,35| Show InChI InChI=1S/C29H34N2O2/c1-18-29(30-17-33-18)14-13-26-24-11-7-20-15-22(32)10-12-23(20)27(24)25(16-28(26,29)2)19-5-8-21(9-6-19)31(3)4/h5-6,8-9,15,17,24-26H,1,7,10-14,16H2,2-4H3/t24-,25+,26-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222087 ((3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyph...) Show SMILES COc1ccc(cc1F)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C29H32FNO3/c1-16-29(31-17(2)34-16)12-11-24-22-8-5-18-13-20(32)7-9-21(18)27(22)23(15-28(24,29)3)19-6-10-26(33-4)25(30)14-19/h6,10,13-14,22-24H,1,5,7-9,11-12,15H2,2-4H3/t22-,23+,24-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222088 ((3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-m...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(OC)c(F)c2)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C30H34FNO3/c1-5-27-32-30(17(2)35-27)13-12-24-22-9-6-18-14-20(33)8-10-21(18)28(22)23(16-29(24,30)3)19-7-11-26(34-4)25(31)15-19/h7,11,14-15,22-24H,2,5-6,8-10,12-13,16H2,1,3-4H3/t22-,23+,24-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50222090 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-15'-...) Show SMILES CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=COC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |c:19,t:28,35| Show InChI InChI=1S/C29H31NO3/c1-17(31)19-4-6-20(7-5-19)25-15-28(3)26(12-13-29(28)18(2)33-16-30-29)24-10-8-21-14-22(32)9-11-23(21)27(24)25/h4-7,14,16,24-26H,2,8-13,15H2,1,3H3/t24-,25+,26-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair