Compile Data Set for Download or QSAR

Found 178 hits with Last Name = 'corjay' and Initial = 'mh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85530 (Nor-d-fenfluramine | Nor-dexfenfluramine | Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85530 (Nor-d-fenfluramine | Nor-dexfenfluramine | Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85598 (l-norfenfluramine) Show SMILES C[C@@H](N)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85598 (l-norfenfluramine) Show SMILES C[C@@H](N)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85530 (Nor-d-fenfluramine | Nor-dexfenfluramine | Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85598 (l-norfenfluramine) Show SMILES C[C@@H](N)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3/t7-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	267	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85597 (CAS_37577-24-5 | NSC_65801 | l-Fenfluramine) Show SMILES CCN[C@H](C)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85597 (CAS_37577-24-5 | NSC_65801 | l-Fenfluramine) Show SMILES CCN[C@H](C)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85597 (CAS_37577-24-5 | NSC_65801 | l-Fenfluramine) Show SMILES CCN[C@H](C)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM85596 (CAS_3239-45-0 | NSC_65801 | d-Fenfluramine) Show SMILES CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM85596 (CAS_3239-45-0 | NSC_65801 | d-Fenfluramine) Show SMILES CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP Ki Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083811 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)C(O)=O Show InChI InChI=1S/C26H31N7O5S/c1-16-11-17(2)23(18(3)12-16)39(37,38)32-21(25(35)36)15-30-24(34)19-5-6-22-20(13-19)14-31-33(22)10-4-7-27-26-28-8-9-29-26/h5-6,8-9,11-14,21,32H,4,7,10,15H2,1-3H3,(H,30,34)(H,35,36)(H2,27,28,29)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083839 (2-Benzyloxycarbonylamino-3-({1-[3-(4,5-dihydro-1H-...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNC3=NCCN3)ncc2c1)NC(=O)OCc1ccccc1 |t:17| Show InChI InChI=1S/C25H29N7O5/c33-22(29-15-20(23(34)35)31-25(36)37-16-17-5-2-1-3-6-17)18-7-8-21-19(13-18)14-30-32(21)12-4-9-26-24-27-10-11-28-24/h1-3,5-8,13-14,20H,4,9-12,15-16H2,(H,29,33)(H,31,36)(H,34,35)(H2,26,27,28)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbition of Vitronectin receptor (alpha V beta 3) binding				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083766 (2-(3,5-Dichloro-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccccc1 |t:8| Show InChI InChI=1S/C26H28Cl2N6O6S/c27-19-12-17(16-6-2-1-3-7-16)13-20(28)23(19)41(38,39)34-22(25(36)37)15-32-24(35)21-14-18(40-33-21)8-4-5-9-29-26-30-10-11-31-26/h1-3,6-7,10-13,18,22,34H,4-5,8-9,14-15H2,(H,32,35)(H,36,37)(H2,29,30,31)/t18?,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083823 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C27H27N7O5S/c35-25(20-7-9-24-21(14-20)16-32-34(24)13-3-10-28-27-29-11-12-30-27)31-17-23(26(36)37)33-40(38,39)22-8-6-18-4-1-2-5-19(18)15-22/h1-2,4-9,11-12,14-16,23,33H,3,10,13,17H2,(H,31,35)(H,36,37)(H2,28,29,30)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083797 (2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({1-[3...) Show SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)C(O)=O)-c1ccccc1 Show InChI InChI=1S/C31H33N7O5S/c1-20-15-24(22-7-4-3-5-8-22)16-21(2)28(20)44(42,43)37-26(30(40)41)19-35-29(39)23-9-10-27-25(17-23)18-36-38(27)14-6-11-32-31-33-12-13-34-31/h3-5,7-10,12-13,15-18,26,37H,6,11,14,19H2,1-2H3,(H,35,39)(H,40,41)(H2,32,33,34)/t26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083788 (2-(2-Chloro-6-methyl-benzenesulfonylamino)-3-({5-[...) Show SMILES Cc1cccc(Cl)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:18| Show InChI InChI=1S/C21H27ClN6O6S/c1-13-5-4-7-15(22)18(13)35(32,33)28-17(20(30)31)12-26-19(29)16-11-14(34-27-16)6-2-3-8-23-21-24-9-10-25-21/h4-5,7,9-10,14,17,28H,2-3,6,8,11-12H2,1H3,(H,26,29)(H,30,31)(H2,23,24,25)/t14?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083803 (2-Benzyloxycarbonylamino-3-({1-[3-(4,5-dihydro-1H-...) Show SMILES OC(=O)[C@H](CNC(=O)c1cccc2n(CCCNC3=NCCN3)ncc12)NC(=O)OCc1ccccc1 |t:18| Show InChI InChI=1S/C25H29N7O5/c33-22(29-15-20(23(34)35)31-25(36)37-16-17-6-2-1-3-7-17)18-8-4-9-21-19(18)14-30-32(21)13-5-10-26-24-27-11-12-28-24/h1-4,6-9,14,20H,5,10-13,15-16H2,(H,29,33)(H,31,36)(H,34,35)(H2,26,27,28)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbition of Vitronectin receptor (alpha V beta 3) binding				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083836 (2-(2,6-Dichloro-benzenesulfonylamino)-3-({1-[3-(1H...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C23H23Cl2N7O5S/c24-16-3-1-4-17(25)20(16)38(36,37)31-18(22(34)35)13-29-21(33)14-5-6-19-15(11-14)12-30-32(19)10-2-7-26-23-27-8-9-28-23/h1,3-6,8-9,11-12,18,31H,2,7,10,13H2,(H,29,33)(H,34,35)(H2,26,27,28)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083789 (2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O)-c1ccccc1 |t:18| Show InChI InChI=1S/C28H34N6O6S/c1-18-14-21(20-8-4-3-5-9-20)15-19(2)25(18)41(38,39)34-24(27(36)37)17-32-26(35)23-16-22(40-33-23)10-6-7-11-29-28-30-12-13-31-28/h3-5,8-9,12-15,22,24,34H,6-7,10-11,16-17H2,1-2H3,(H,32,35)(H,36,37)(H2,29,30,31)/t22?,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083837 (2-(4-Chloro-benzenesulfonylamino)-3-({1-[3-(1H-imi...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C23H24ClN7O5S/c24-17-3-5-18(6-4-17)37(35,36)30-19(22(33)34)14-28-21(32)15-2-7-20-16(12-15)13-29-31(20)11-1-8-25-23-26-9-10-27-23/h2-7,9-10,12-13,19,30H,1,8,11,14H2,(H,28,32)(H,33,34)(H2,25,26,27)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083807 (2-(3,4-Dichloro-benzenesulfonylamino)-3-({1-[3-(1H...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H23Cl2N7O5S/c24-17-4-3-16(11-18(17)25)38(36,37)31-19(22(34)35)13-29-21(33)14-2-5-20-15(10-14)12-30-32(20)9-1-6-26-23-27-7-8-28-23/h2-5,7-8,10-12,19,31H,1,6,9,13H2,(H,29,33)(H,34,35)(H2,26,27,28)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083810 (2-(2,6-Dimethyl-benzenesulfonylamino)-3-({1-[3-(1H...) Show SMILES Cc1cccc(C)c1S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)C(O)=O Show InChI InChI=1S/C25H29N7O5S/c1-16-5-3-6-17(2)22(16)38(36,37)31-20(24(34)35)15-29-23(33)18-7-8-21-19(13-18)14-30-32(21)12-4-9-26-25-27-10-11-28-25/h3,5-8,10-11,13-14,20,31H,4,9,12,15H2,1-2H3,(H,29,33)(H,34,35)(H2,26,27,28)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083768 ((S)3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dih...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C20H26N6O6S/c27-18(16-12-14(32-25-16)6-4-5-9-21-20-22-10-11-23-20)24-13-17(19(28)29)26-33(30,31)15-7-2-1-3-8-15/h1-3,7-8,10-11,14,17,26H,4-6,9,12-13H2,(H,24,27)(H,28,29)(H2,21,22,23)/t14?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083768 ((S)3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dih...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C20H26N6O6S/c27-18(16-12-14(32-25-16)6-4-5-9-21-20-22-10-11-23-20)24-13-17(19(28)29)26-33(30,31)15-7-2-1-3-8-15/h1-3,7-8,10-11,14,17,26H,4-6,9,12-13H2,(H,24,27)(H,28,29)(H2,21,22,23)/t14?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083836 (2-(2,6-Dichloro-benzenesulfonylamino)-3-({1-[3-(1H...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C23H23Cl2N7O5S/c24-16-3-1-4-17(25)20(16)38(36,37)31-18(22(34)35)13-29-21(33)14-5-6-19-15(11-14)12-30-32(19)10-2-7-26-23-27-8-9-28-23/h1,3-6,8-9,11-12,18,31H,2,7,10,13H2,(H,29,33)(H,34,35)(H2,26,27,28)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of aggregation of human gel-purified platelets (GPIIbIIIa GPP)				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083812 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H27N7O5S/c35-25(19-9-10-23-20(15-19)16-32-34(23)14-4-11-28-27-29-12-13-30-27)31-17-22(26(36)37)33-40(38,39)24-8-3-6-18-5-1-2-7-21(18)24/h1-3,5-10,12-13,15-16,22,33H,4,11,14,17H2,(H,31,35)(H,36,37)(H2,28,29,30)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083769 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C23H32N6O6S/c1-14-10-15(2)20(16(3)11-14)36(33,34)29-19(22(31)32)13-27-21(30)18-12-17(35-28-18)6-4-5-7-24-23-25-8-9-26-23/h8-11,17,19,29H,4-7,12-13H2,1-3H3,(H,27,30)(H,31,32)(H2,24,25,26)/t17?,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083833 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES Cc1ccc(cc1)S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)C(O)=O Show InChI InChI=1S/C24H27N7O5S/c1-16-3-6-19(7-4-16)37(35,36)30-20(23(33)34)15-28-22(32)17-5-8-21-18(13-17)14-29-31(21)12-2-9-25-24-26-10-11-27-24/h3-8,10-11,13-14,20,30H,2,9,12,15H2,1H3,(H,28,32)(H,33,34)(H2,25,26,27)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083783 (2-(2,6-Dichloro-benzenesulfonylamino)-3-({5-[4-(1H...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1c(Cl)cccc1Cl |t:8| Show InChI InChI=1S/C20H24Cl2N6O6S/c21-13-5-3-6-14(22)17(13)35(32,33)28-16(19(30)31)11-26-18(29)15-10-12(34-27-15)4-1-2-7-23-20-24-8-9-25-20/h3,5-6,8-9,12,16,28H,1-2,4,7,10-11H2,(H,26,29)(H,30,31)(H2,23,24,25)/t12?,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083811 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)C(O)=O Show InChI InChI=1S/C26H31N7O5S/c1-16-11-17(2)23(18(3)12-16)39(37,38)32-21(25(35)36)15-30-24(34)19-5-6-22-20(13-19)14-31-33(22)10-4-7-27-26-28-8-9-29-26/h5-6,8-9,11-14,21,32H,4,7,10,15H2,1-3H3,(H,30,34)(H,35,36)(H2,27,28,29)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of aggregation of human gel-purified platelets (GPIIbIIIa GPP)				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083793 (2-Benzyloxycarbonylamino-3-({2-[3-(4,5-dihydro-1H-...) Show SMILES OC(=O)[C@@H](CNC(=O)c1ccc2cn(CCCNC3=NCCN3)nc2c1)NC(=O)OCc1ccccc1 |t:18| Show InChI InChI=1S/C25H29N7O5/c33-22(29-14-21(23(34)35)30-25(36)37-16-17-5-2-1-3-6-17)18-7-8-19-15-32(31-20(19)13-18)12-4-9-26-24-27-10-11-28-24/h1-3,5-8,13,15,21H,4,9-12,14,16H2,(H,29,33)(H,30,36)(H,34,35)(H2,26,27,28)/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbition of Vitronectin receptor (alpha V beta 3) binding				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083802 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)c1cccc2n(CCCNc3ncc[nH]3)ncc12)C(O)=O Show InChI InChI=1S/C26H31N7O5S/c1-16-12-17(2)23(18(3)13-16)39(37,38)32-21(25(35)36)15-30-24(34)19-6-4-7-22-20(19)14-31-33(22)11-5-8-27-26-28-9-10-29-26/h4,6-7,9-10,12-14,21,32H,5,8,11,15H2,1-3H3,(H,30,34)(H,35,36)(H2,27,28,29)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alphaV-beta3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083791 (3-({5-[3-(6-Amino-pyridin-2-yl)-propyl]-4,5-dihydr...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCc2cccc(N)n2)C1)C(O)=O |t:19| Show InChI InChI=1S/C24H31N5O6S/c1-14-10-15(2)22(16(3)11-14)36(33,34)29-20(24(31)32)13-26-23(30)19-12-18(35-28-19)8-4-6-17-7-5-9-21(25)27-17/h5,7,9-11,18,20,29H,4,6,8,12-13H2,1-3H3,(H2,25,27)(H,26,30)(H,31,32)/t18?,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083809 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES COc1ccc(cc1)S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)C(O)=O Show InChI InChI=1S/C24H27N7O6S/c1-37-18-4-6-19(7-5-18)38(35,36)30-20(23(33)34)15-28-22(32)16-3-8-21-17(13-16)14-29-31(21)12-2-9-25-24-26-10-11-27-24/h3-8,10-11,13-14,20,30H,2,9,12,15H2,1H3,(H,28,32)(H,33,34)(H2,25,26,27)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083814 (3-({1-[3-(1,4,5,6-Tetrahydro-pyrimidin-2-ylamino)-...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNC3=NCCCN3)ncc2c1)C(O)=O |t:28| Show InChI InChI=1S/C27H35N7O5S/c1-17-12-18(2)24(19(3)13-17)40(38,39)33-22(26(36)37)16-31-25(35)20-6-7-23-21(14-20)15-32-34(23)11-5-10-30-27-28-8-4-9-29-27/h6-7,12-15,22,33H,4-5,8-11,16H2,1-3H3,(H,31,35)(H,36,37)(H2,28,29,30)/t22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of adhesion of integrin beta3-transfected HEK293 cells to fibrinogen				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083785 (3-({5-[3-(1H-Imidazol-2-ylcarbamoyl)-propyl]-4,5-d...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCC(=O)Nc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C23H30N6O7S/c1-13-9-14(2)20(15(3)10-13)37(34,35)29-18(22(32)33)12-26-21(31)17-11-16(36-28-17)5-4-6-19(30)27-23-24-7-8-25-23/h7-10,16,18,29H,4-6,11-12H2,1-3H3,(H,26,31)(H,32,33)(H2,24,25,27,30)/t16?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083785 (3-({5-[3-(1H-Imidazol-2-ylcarbamoyl)-propyl]-4,5-d...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCC(=O)Nc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C23H30N6O7S/c1-13-9-14(2)20(15(3)10-13)37(34,35)29-18(22(32)33)12-26-21(31)17-11-16(36-28-17)5-4-6-19(30)27-23-24-7-8-25-23/h7-10,16,18,29H,4-6,11-12H2,1-3H3,(H,26,31)(H,32,33)(H2,24,25,27,30)/t16?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083775 (3-[(5-{2-[3-(1H-Imidazol-2-yl)-ureido]-ethyl}-4,5-...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCNC(=O)Nc2ncc[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C22H29N7O7S/c1-12-8-13(2)18(14(3)9-12)37(34,35)29-17(20(31)32)11-26-19(30)16-10-15(36-28-16)4-5-25-22(33)27-21-23-6-7-24-21/h6-9,15,17,29H,4-5,10-11H2,1-3H3,(H,26,30)(H,31,32)(H3,23,24,25,27,33)/t15?,17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083799 (2-Benzenesulfonylamino-3-({1-[3-(1H-imidazol-2-yla...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H25N7O5S/c31-21(27-15-19(22(32)33)29-36(34,35)18-5-2-1-3-6-18)16-7-8-20-17(13-16)14-28-30(20)12-4-9-24-23-25-10-11-26-23/h1-3,5-8,10-11,13-14,19,29H,4,9,12,15H2,(H,27,31)(H,32,33)(H2,24,25,26)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of aggregation of human gel-purified platelets (GPIIbIIIa GPP)				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083805 (2-(Biphenyl-4-sulfonylamino)-3-({1-[3-(1H-imidazol...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C29H29N7O5S/c37-27(22-9-12-26-23(17-22)18-34-36(26)16-4-13-30-29-31-14-15-32-29)33-19-25(28(38)39)35-42(40,41)24-10-7-21(8-11-24)20-5-2-1-3-6-20/h1-3,5-12,14-15,17-18,25,35H,4,13,16,19H2,(H,33,37)(H,38,39)(H2,30,31,32)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50083812 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H27N7O5S/c35-25(19-9-10-23-20(15-19)16-32-34(23)14-4-11-28-27-29-12-13-30-27)31-17-22(26(36)37)33-40(38,39)24-8-3-6-18-5-1-2-7-21(18)24/h1-3,5-10,12-13,15-16,22,33H,4,11,14,17H2,(H,31,35)(H,36,37)(H2,28,29,30)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of aggregation of human gel-purified platelets (GPIIbIIIa GPP)				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083799 (2-Benzenesulfonylamino-3-({1-[3-(1H-imidazol-2-yla...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H25N7O5S/c31-21(27-15-19(22(32)33)29-36(34,35)18-5-2-1-3-6-18)16-7-8-20-17(13-16)14-28-30(20)12-4-9-24-23-25-10-11-26-23/h1-3,5-8,10-11,13-14,19,29H,4,9,12,15H2,(H,27,31)(H,32,33)(H2,24,25,26)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083780 (2-(3,5-Dimethyl-biphenyl-4-sulfonylamino)-3-({5-[4...) Show SMILES Cc1cc(cc(C)c1S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O)-c1ccccc1 |t:18| Show InChI InChI=1S/C30H35N5O6S/c1-20-16-23(22-10-4-3-5-11-22)17-21(2)28(20)42(39,40)35-26(30(37)38)19-33-29(36)25-18-24(41-34-25)12-6-8-14-31-27-13-7-9-15-32-27/h3-5,7,9-11,13,15-17,24,26,35H,6,8,12,14,18-19H2,1-2H3,(H,31,32)(H,33,36)(H,37,38)/t24?,26-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083770 (3-({5-[3-(2-Amino-1H-imidazol-4-yl)-propyl]-4,5-di...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCc2cnc(N)[nH]2)C1)C(O)=O |t:19| Show InChI InChI=1S/C22H30N6O6S/c1-12-7-13(2)19(14(3)8-12)35(32,33)28-18(21(30)31)11-24-20(29)17-9-16(34-27-17)6-4-5-15-10-25-22(23)26-15/h7-8,10,16,18,28H,4-6,9,11H2,1-3H3,(H,24,29)(H,30,31)(H3,23,25,26)/t16?,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083813 (3-({1-[3-(Pyridin-2-ylamino)-propyl]-1H-indazole-5...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNc3ccccn3)ncc2c1)C(O)=O Show InChI InChI=1S/C28H32N6O5S/c1-18-13-19(2)26(20(3)14-18)40(38,39)33-23(28(36)37)17-31-27(35)21-8-9-24-22(15-21)16-32-34(24)12-6-11-30-25-7-4-5-10-29-25/h4-5,7-10,13-16,23,33H,6,11-12,17H2,1-3H3,(H,29,30)(H,31,35)(H,36,37)/t23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083767 (3-({5-[4-(1H-Imidazol-2-ylamino)-butyl]-4,5-dihydr...) Show SMILES OC(=O)[C@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)NS(=O)(=O)c1cccc2ccccc12 |t:8| Show InChI InChI=1S/C24H28N6O6S/c31-22(19-14-17(36-29-19)8-3-4-11-25-24-26-12-13-27-24)28-15-20(23(32)33)30-37(34,35)21-10-5-7-16-6-1-2-9-18(16)21/h1-2,5-7,9-10,12-13,17,20,30H,3-4,8,11,14-15H2,(H,28,31)(H,32,33)(H2,25,26,27)/t17?,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083801 (2-Benzyloxycarbonylamino-3-({1-[2-(4,5-dihydro-1H-...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCNC3=NCCN3)ncc2c1)NC(=O)OCc1ccccc1 |t:16| Show InChI InChI=1S/C24H27N7O5/c32-21(28-14-19(22(33)34)30-24(35)36-15-16-4-2-1-3-5-16)17-6-7-20-18(12-17)13-29-31(20)11-10-27-23-25-8-9-26-23/h1-7,12-13,19H,8-11,14-15H2,(H,28,32)(H,30,35)(H,33,34)(H2,25,26,27)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbition of Vitronectin receptor (alpha V beta 3) binding				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083816 (3-({1-[3-(1H-Imidazol-2-ylamino)-propyl]-1H-indazo...) Show SMILES OC(=O)[C@H](CNC(=O)c1ccc2n(CCCNc3ncc[nH]3)ncc2c1)NS(=O)(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C24H24F3N7O5S/c25-24(26,27)17-3-5-18(6-4-17)40(38,39)33-19(22(36)37)14-31-21(35)15-2-7-20-16(12-15)13-32-34(20)11-1-8-28-23-29-9-10-30-23/h2-7,9-10,12-13,19,33H,1,8,11,14H2,(H,31,35)(H,36,37)(H2,28,29,30)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assay				J Med Chem 43: 41-58 (2000) BindingDB Entry DOI: 10.7270/Q21G0KG2
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50083781 (3-({5-[4-(Pyridin-2-ylamino)-butyl]-4,5-dihydro-is...) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)C1=NOC(CCCCNc2ccccn2)C1)C(O)=O |t:19| Show InChI InChI=1S/C25H33N5O6S/c1-16-12-17(2)23(18(3)13-16)37(34,35)30-21(25(32)33)15-28-24(31)20-14-19(36-29-20)8-4-6-10-26-22-9-5-7-11-27-22/h5,7,9,11-13,19,21,30H,4,6,8,10,14-15H2,1-3H3,(H,26,27)(H,28,31)(H,32,33)/t19?,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogen				J Med Chem 43: 27-40 (2000) BindingDB Entry DOI: 10.7270/Q2571B77
					More data for this Ligand-Target Pair

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