Compile Data Set for Download or QSAR

Found 120 hits with Last Name = 'crews' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13911 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(O)=O Show InChI InChI=1S/C23H20N6O2/c1-2-18-19(23(30)31)13-29-21(18)22(24-14-26-29)27-17-8-9-20-16(10-17)11-25-28(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H,30,31)(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13911 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(O)=O Show InChI InChI=1S/C23H20N6O2/c1-2-18-19(23(30)31)13-29-21(18)22(24-14-26-29)27-17-8-9-20-16(10-17)11-25-28(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H,30,31)(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13921 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NCCCn1ccnc1 Show InChI InChI=1S/C29H29N9O/c1-2-24-25(29(39)31-11-6-13-36-14-12-30-20-36)18-38-27(24)28(32-19-34-38)35-23-9-10-26-22(15-23)16-33-37(26)17-21-7-4-3-5-8-21/h3-5,7-10,12,14-16,18-20H,2,6,11,13,17H2,1H3,(H,31,39)(H,32,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13921 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NCCCn1ccnc1 Show InChI InChI=1S/C29H29N9O/c1-2-24-25(29(39)31-11-6-13-36-14-12-30-20-36)18-38-27(24)28(32-19-34-38)35-23-9-10-26-22(15-23)16-33-37(26)17-21-7-4-3-5-8-21/h3-5,7-10,12,14-16,18-20H,2,6,11,13,17H2,1H3,(H,31,39)(H,32,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13911 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(O)=O Show InChI InChI=1S/C23H20N6O2/c1-2-18-19(23(30)31)13-29-21(18)22(24-14-26-29)27-17-8-9-20-16(10-17)11-25-28(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H,30,31)(H,24,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13911 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(O)=O Show InChI InChI=1S/C23H20N6O2/c1-2-18-19(23(30)31)13-29-21(18)22(24-14-26-29)27-17-8-9-20-16(10-17)11-25-28(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H,30,31)(H,24,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13923 (2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...) Show SMILES CCc1c(NC(=O)OCCn2ccnc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C28H27N9O2/c1-2-23-24(34-28(38)39-13-12-35-11-10-29-19-35)17-37-26(23)27(30-18-32-37)33-22-8-9-25-21(14-22)15-31-36(25)16-20-6-4-3-5-7-20/h3-11,14-15,17-19H,2,12-13,16H2,1H3,(H,34,38)(H,30,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13923 (2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...) Show SMILES CCc1c(NC(=O)OCCn2ccnc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C28H27N9O2/c1-2-23-24(34-28(38)39-13-12-35-11-10-29-19-35)17-37-26(23)27(30-18-32-37)33-22-8-9-25-21(14-22)15-31-36(25)16-20-6-4-3-5-7-20/h3-11,14-15,17-19H,2,12-13,16H2,1H3,(H,34,38)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13921 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NCCCn1ccnc1 Show InChI InChI=1S/C29H29N9O/c1-2-24-25(29(39)31-11-6-13-36-14-12-30-20-36)18-38-27(24)28(32-19-34-38)35-23-9-10-26-22(15-23)16-33-37(26)17-21-7-4-3-5-8-21/h3-5,7-10,12,14-16,18-20H,2,6,11,13,17H2,1H3,(H,31,39)(H,32,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13921 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NCCCn1ccnc1 Show InChI InChI=1S/C29H29N9O/c1-2-24-25(29(39)31-11-6-13-36-14-12-30-20-36)18-38-27(24)28(32-19-34-38)35-23-9-10-26-22(15-23)16-33-37(26)17-21-7-4-3-5-8-21/h3-5,7-10,12,14-16,18-20H,2,6,11,13,17H2,1H3,(H,31,39)(H,32,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13923 (2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...) Show SMILES CCc1c(NC(=O)OCCn2ccnc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C28H27N9O2/c1-2-23-24(34-28(38)39-13-12-35-11-10-29-19-35)17-37-26(23)27(30-18-32-37)33-22-8-9-25-21(14-22)15-31-36(25)16-20-6-4-3-5-7-20/h3-11,14-15,17-19H,2,12-13,16H2,1H3,(H,34,38)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13923 (2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indaz...) Show SMILES CCc1c(NC(=O)OCCn2ccnc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C28H27N9O2/c1-2-23-24(34-28(38)39-13-12-35-11-10-29-19-35)17-37-26(23)27(30-18-32-37)33-22-8-9-25-21(14-22)15-31-36(25)16-20-6-4-3-5-7-20/h3-11,14-15,17-19H,2,12-13,16H2,1H3,(H,34,38)(H,30,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13902 (CHEMBL372112 | ethyl 5-ethyl-4-(1H-indazol-5-ylami...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4[nH]ncc4c3)c2c1CC Show InChI InChI=1S/C18H18N6O2/c1-3-13-14(18(25)26-4-2)9-24-16(13)17(19-10-21-24)22-12-5-6-15-11(7-12)8-20-23-15/h5-10H,3-4H2,1-2H3,(H,20,23)(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13902 (CHEMBL372112 | ethyl 5-ethyl-4-(1H-indazol-5-ylami...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4[nH]ncc4c3)c2c1CC Show InChI InChI=1S/C18H18N6O2/c1-3-13-14(18(25)26-4-2)9-24-16(13)17(19-10-21-24)22-12-5-6-15-11(7-12)8-20-23-15/h5-10H,3-4H2,1-2H3,(H,20,23)(H,19,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50187907 (CHEMBL213184 | N-(3-aminopropyl)-N-((3-benzyl-7-ch...) Show SMILES Cc1ccc(cc1)C(=O)N(CCCN)C(C1CC1)c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C28H30ClN5O2/c1-19-8-10-22(11-9-19)27(35)32(17-5-16-30)25(21-12-13-21)26-31-34-23(14-15-24(34)29)28(36)33(26)18-20-6-3-2-4-7-20/h2-4,6-11,14-15,21,25H,5,12-13,16-18,30H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Eg5 ATPase activity				Bioorg Med Chem Lett 16: 3937-42 (2006) Article DOI: 10.1016/j.bmcl.2006.05.037 BindingDB Entry DOI: 10.7270/Q2RV0PGM
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13901 (CHEMBL370934 | ethyl 4-[(3-bromophenyl)amino]-5-et...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3cccc(Br)c3)c2c1CC Show InChI InChI=1S/C17H17BrN4O2/c1-3-13-14(17(23)24-4-2)9-22-15(13)16(19-10-20-22)21-12-7-5-6-11(18)8-12/h5-10H,3-4H2,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13901 (CHEMBL370934 | ethyl 4-[(3-bromophenyl)amino]-5-et...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3cccc(Br)c3)c2c1CC Show InChI InChI=1S/C17H17BrN4O2/c1-3-13-14(17(23)24-4-2)9-22-15(13)16(19-10-20-22)21-12-7-5-6-11(18)8-12/h5-10H,3-4H2,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50187899 (CHEMBL209815 | N-(3-aminopropyl)-N-(1-(3-benzyl-7-...) Show SMILES CCC(N(CCCN)C(=O)c1ccc(Cl)cc1)c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C26H27Cl2N5O2/c1-2-21(31(16-6-15-29)25(34)19-9-11-20(27)12-10-19)24-30-33-22(13-14-23(33)28)26(35)32(24)17-18-7-4-3-5-8-18/h3-5,7-14,21H,2,6,15-17,29H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Eg5 ATPase activity				Bioorg Med Chem Lett 16: 3937-42 (2006) Article DOI: 10.1016/j.bmcl.2006.05.037 BindingDB Entry DOI: 10.7270/Q2RV0PGM
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50187900 (CHEMBL213686 | N-(3-aminopropyl)-N-(1-(3-benzyl-7-...) Show SMILES CCC(N(CCCN)C(=O)c1ccc(C)cc1)c1nn2c(Cl)ccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C27H30ClN5O2/c1-3-22(31(17-7-16-29)26(34)21-12-10-19(2)11-13-21)25-30-33-23(14-15-24(33)28)27(35)32(25)18-20-8-5-4-6-9-20/h4-6,8-15,22H,3,7,16-18,29H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Eg5 ATPase activity				Bioorg Med Chem Lett 16: 3937-42 (2006) Article DOI: 10.1016/j.bmcl.2006.05.037 BindingDB Entry DOI: 10.7270/Q2RV0PGM
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13913 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-meth...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NC Show InChI InChI=1S/C24H23N7O/c1-3-19-20(24(32)25-2)14-31-22(19)23(26-15-28-31)29-18-9-10-21-17(11-18)12-27-30(21)13-16-7-5-4-6-8-16/h4-12,14-15H,3,13H2,1-2H3,(H,25,32)(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13913 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-meth...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NC Show InChI InChI=1S/C24H23N7O/c1-3-19-20(24(32)25-2)14-31-22(19)23(26-15-28-31)29-18-9-10-21-17(11-18)12-27-30(21)13-16-7-5-4-6-8-16/h4-12,14-15H,3,13H2,1-2H3,(H,25,32)(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50187894 (CHEMBL535161 | N-(3-aminopropyl)-N-(1-(3-benzyl-5-...) Show SMILES CCC(N(CCCN)C(=O)c1ccc(C)cc1)c1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C27H30ClN5O2/c1-3-23(31(16-7-15-29)26(34)21-12-10-19(2)11-13-21)25-30-33-17-14-22(28)24(33)27(35)32(25)18-20-8-5-4-6-9-20/h4-6,8-14,17,23H,3,7,15-16,18,29H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Eg5 ATPase activity				Bioorg Med Chem Lett 16: 3937-42 (2006) Article DOI: 10.1016/j.bmcl.2006.05.037 BindingDB Entry DOI: 10.7270/Q2RV0PGM
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50187893 (CHEMBL214404 | N-(3-aminopropyl)-N-(1-(3-benzyl-4-...) Show SMILES CCC(N(CCCN)C(=O)c1ccc(C)cc1)c1nn2cccc2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C27H31N5O2/c1-3-23(30(17-8-16-28)26(33)22-14-12-20(2)13-15-22)25-29-32-18-7-11-24(32)27(34)31(25)19-21-9-5-4-6-10-21/h4-7,9-15,18,23H,3,8,16-17,19,28H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Eg5 ATPase activity				Bioorg Med Chem Lett 16: 3937-42 (2006) Article DOI: 10.1016/j.bmcl.2006.05.037 BindingDB Entry DOI: 10.7270/Q2RV0PGM
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13900 (CHEMBL196018 | ethyl 4-[(3-chloro-4-fluorophenyl)a...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc(F)c(Cl)c3)c2c1CC Show InChI InChI=1S/C17H16ClFN4O2/c1-3-11-12(17(24)25-4-2)8-23-15(11)16(20-9-21-23)22-10-5-6-14(19)13(18)7-10/h5-9H,3-4H2,1-2H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13900 (CHEMBL196018 | ethyl 4-[(3-chloro-4-fluorophenyl)a...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc(F)c(Cl)c3)c2c1CC Show InChI InChI=1S/C17H16ClFN4O2/c1-3-11-12(17(24)25-4-2)8-23-15(11)16(20-9-21-23)22-10-5-6-14(19)13(18)7-10/h5-9H,3-4H2,1-2H3,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50187895 (CHEMBL380294 | N-(3-aminopropyl)-N-((3-benzyl-5-ch...) Show SMILES Cc1ccc(cc1)C(=O)N(CCCN)C(C1CC1)c1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C28H30ClN5O2/c1-19-8-10-22(11-9-19)27(35)32(16-5-15-30)24(21-12-13-21)26-31-34-17-14-23(29)25(34)28(36)33(26)18-20-6-3-2-4-7-20/h2-4,6-11,14,17,21,24H,5,12-13,15-16,18,30H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Eg5 ATPase activity				Bioorg Med Chem Lett 16: 3937-42 (2006) Article DOI: 10.1016/j.bmcl.2006.05.037 BindingDB Entry DOI: 10.7270/Q2RV0PGM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13912 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(N)=O Show InChI InChI=1S/C23H21N7O/c1-2-18-19(22(24)31)13-30-21(18)23(25-14-27-30)28-17-8-9-20-16(10-17)11-26-29(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H2,24,31)(H,25,27,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13912 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(N)=O Show InChI InChI=1S/C23H21N7O/c1-2-18-19(22(24)31)13-30-21(18)23(25-14-27-30)28-17-8-9-20-16(10-17)11-26-29(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H2,24,31)(H,25,27,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13912 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(N)=O Show InChI InChI=1S/C23H21N7O/c1-2-18-19(22(24)31)13-30-21(18)23(25-14-27-30)28-17-8-9-20-16(10-17)11-26-29(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H2,24,31)(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13906 (CHEMBL425738 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnn2c1 Show InChI InChI=1S/C23H20N6O2/c1-2-31-23(30)18-11-21-22(24-15-26-29(21)14-18)27-19-8-9-20-17(10-19)12-25-28(20)13-16-6-4-3-5-7-16/h3-12,14-15H,2,13H2,1H3,(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13904 (CHEMBL196925 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC Show InChI InChI=1S/C25H24N6O2/c1-3-20-21(25(32)33-4-2)15-31-23(20)24(26-16-28-31)29-19-10-11-22-18(12-19)13-27-30(22)14-17-8-6-5-7-9-17/h5-13,15-16H,3-4,14H2,1-2H3,(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13904 (CHEMBL196925 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC Show InChI InChI=1S/C25H24N6O2/c1-3-20-21(25(32)33-4-2)15-31-23(20)24(26-16-28-31)29-19-10-11-22-18(12-19)13-27-30(22)14-17-8-6-5-7-9-17/h5-13,15-16H,3-4,14H2,1-2H3,(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13912 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(N)=O Show InChI InChI=1S/C23H21N7O/c1-2-18-19(22(24)31)13-30-21(18)23(25-14-27-30)28-17-8-9-20-16(10-17)11-26-29(20)12-15-6-4-3-5-7-15/h3-11,13-14H,2,12H2,1H3,(H2,24,31)(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13906 (CHEMBL425738 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnn2c1 Show InChI InChI=1S/C23H20N6O2/c1-2-31-23(30)18-11-21-22(24-15-26-29(21)14-18)27-19-8-9-20-17(10-19)12-25-28(20)13-16-6-4-3-5-7-16/h3-12,14-15H,2,13H2,1H3,(H,24,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13913 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-meth...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NC Show InChI InChI=1S/C24H23N7O/c1-3-19-20(24(32)25-2)14-31-22(19)23(26-15-28-31)29-18-9-10-21-17(11-18)12-27-30(21)13-16-7-5-4-6-8-16/h4-12,14-15H,3,13H2,1-2H3,(H,25,32)(H,26,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13913 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-meth...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)NC Show InChI InChI=1S/C24H23N7O/c1-3-19-20(24(32)25-2)14-31-22(19)23(26-15-28-31)29-18-9-10-21-17(11-18)12-27-30(21)13-16-7-5-4-6-8-16/h4-12,14-15H,3,13H2,1-2H3,(H,25,32)(H,26,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13915 (CHEMBL372523 | benzyl N-{4-[(1-benzyl-1H-indazol-5...) Show SMILES CCc1c(NC(=O)OCc2ccccc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C30H27N7O2/c1-2-25-26(35-30(38)39-19-22-11-7-4-8-12-22)18-37-28(25)29(31-20-33-37)34-24-13-14-27-23(15-24)16-32-36(27)17-21-9-5-3-6-10-21/h3-16,18,20H,2,17,19H2,1H3,(H,35,38)(H,31,33,34)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13922 (3-(1H-imidazol-1-yl)propyl 4-[(1-benzyl-1H-indazol...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)OCCCn1ccnc1 Show InChI InChI=1S/C29H28N8O2/c1-2-24-25(29(38)39-14-6-12-35-13-11-30-20-35)18-37-27(24)28(31-19-33-37)34-23-9-10-26-22(15-23)16-32-36(26)17-21-7-4-3-5-8-21/h3-5,7-11,13,15-16,18-20H,2,6,12,14,17H2,1H3,(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13922 (3-(1H-imidazol-1-yl)propyl 4-[(1-benzyl-1H-indazol...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)OCCCn1ccnc1 Show InChI InChI=1S/C29H28N8O2/c1-2-24-25(29(38)39-14-6-12-35-13-11-30-20-35)18-37-27(24)28(31-19-33-37)34-23-9-10-26-22(15-23)16-32-36(26)17-21-7-4-3-5-8-21/h3-5,7-11,13,15-16,18-20H,2,6,12,14,17H2,1H3,(H,31,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13915 (CHEMBL372523 | benzyl N-{4-[(1-benzyl-1H-indazol-5...) Show SMILES CCc1c(NC(=O)OCc2ccccc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12 Show InChI InChI=1S/C30H27N7O2/c1-2-25-26(35-30(38)39-19-22-11-7-4-8-12-22)18-37-28(25)29(31-20-33-37)34-24-13-14-27-23(15-24)16-32-36(27)17-21-9-5-3-6-10-21/h3-16,18,20H,2,17,19H2,1H3,(H,35,38)(H,31,33,34)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13904 (CHEMBL196925 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC Show InChI InChI=1S/C25H24N6O2/c1-3-20-21(25(32)33-4-2)15-31-23(20)24(26-16-28-31)29-19-10-11-22-18(12-19)13-27-30(22)14-17-8-6-5-7-9-17/h5-13,15-16H,3-4,14H2,1-2H3,(H,26,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against HER2 cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM13904 (CHEMBL196925 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1CC Show InChI InChI=1S/C25H24N6O2/c1-3-20-21(25(32)33-4-2)15-31-23(20)24(26-16-28-31)29-19-10-11-22-18(12-19)13-27-30(22)14-17-8-6-5-7-9-17/h5-13,15-16H,3-4,14H2,1-2H3,(H,26,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50187892 (CHEMBL210168 | N-(3-aminopropyl)-N-(1-(3-benzyl-5-...) Show SMILES CCC(N(CCCN)C(=O)c1ccc(Cl)cc1)c1nn2ccc(Cl)c2c(=O)n1Cc1ccccc1 Show InChI InChI=1S/C26H27Cl2N5O2/c1-2-22(31(15-6-14-29)25(34)19-9-11-20(27)12-10-19)24-30-33-16-13-21(28)23(33)26(35)32(24)17-18-7-4-3-5-8-18/h3-5,7-13,16,22H,2,6,14-15,17,29H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Eg5 ATPase activity				Bioorg Med Chem Lett 16: 3937-42 (2006) Article DOI: 10.1016/j.bmcl.2006.05.037 BindingDB Entry DOI: 10.7270/Q2RV0PGM
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13903 (ethyl 5-ethyl-4-{[(1R)-1-phenylethyl]amino}pyrrolo...) Show SMILES CCOC(=O)c1cn2ncnc(N[C@H](C)c3ccccc3)c2c1CC |r| Show InChI InChI=1S/C19H22N4O2/c1-4-15-16(19(24)25-5-2)11-23-17(15)18(20-12-21-23)22-13(3)14-9-7-6-8-10-14/h6-13H,4-5H2,1-3H3,(H,20,21,22)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13907 (CHEMBL196738 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1C Show InChI InChI=1S/C24H22N6O2/c1-3-32-24(31)20-14-30-22(16(20)2)23(25-15-27-30)28-19-9-10-21-18(11-19)12-26-29(21)13-17-7-5-4-6-8-17/h4-12,14-15H,3,13H2,1-2H3,(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13908 (CHEMBL365606 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1C(C)C Show InChI InChI=1S/C26H26N6O2/c1-4-34-26(33)21-15-32-24(23(21)17(2)3)25(27-16-29-32)30-20-10-11-22-19(12-20)13-28-31(22)14-18-8-6-5-7-9-18/h5-13,15-17H,4,14H2,1-3H3,(H,27,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13914 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N,N-di...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)N(C)C Show InChI InChI=1S/C25H25N7O/c1-4-20-21(25(33)30(2)3)15-32-23(20)24(26-16-28-32)29-19-10-11-22-18(12-19)13-27-31(22)14-17-8-6-5-7-9-17/h5-13,15-16H,4,14H2,1-3H3,(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The kinase activity was determined by using recombinant enzyme incubating with its substrate in the presence of test compound and ATP/[gamma-33P] ATP...				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13914 (4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N,N-di...) Show SMILES CCc1c(cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12)C(=O)N(C)C Show InChI InChI=1S/C25H25N7O/c1-4-20-21(25(33)30(2)3)15-32-23(20)24(26-16-28-32)29-19-10-11-22-18(12-19)13-27-31(22)14-17-8-6-5-7-9-17/h5-13,15-16H,4,14H2,1-3H3,(H,26,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50172018 (4-Benzylamino-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin...) Show SMILES CCOC(=O)c1cn2ncnc(NCc3ccccc3)c2c1CC Show InChI InChI=1S/C18H20N4O2/c1-3-14-15(18(23)24-4-2)11-22-16(14)17(20-12-21-22)19-10-13-8-6-5-7-9-13/h5-9,11-12H,3-4,10H2,1-2H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM13907 (CHEMBL196738 | ethyl 4-[(1-benzyl-1H-indazol-5-yl)...) Show SMILES CCOC(=O)c1cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c2c1C Show InChI InChI=1S/C24H22N6O2/c1-3-32-24(31)20-14-30-22(16(20)2)23(25-15-27-30)28-19-9-10-21-18(11-19)12-26-29(21)13-17-7-5-4-6-8-17/h4-12,14-15H,3,13H2,1-2H3,(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibitory concentration against EGFR cytoplasmic sequence expressed in Sf9 cells				Bioorg Med Chem Lett 15: 4774-9 (2005) Article DOI: 10.1016/j.bmcl.2005.07.027 BindingDB Entry DOI: 10.7270/Q2XD1172
					More data for this Ligand-Target Pair

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