Compile Data Set for Download or QSAR

Found 12 hits with Last Name = 'demo' and Initial = 'sd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277781 ((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...) Show SMILES CCOc1cc(no1)C(=O)N[C@@H](COC)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C26H34N4O9/c1-5-37-21-12-18(30-39-21)23(32)28-20(14-36-4)25(34)29-19(13-35-3)24(33)27-17(22(31)26(2)15-38-26)11-16-9-7-6-8-10-16/h6-10,12,17,19-20H,5,11,13-15H2,1-4H3,(H,27,33)(H,28,32)(H,29,34)/t17-,19-,20-,26+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277889 (CARFILZOMIB | CHEMBL451887) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/t31-,32-,33-,34-,40+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277779 (CHEMBL484003 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(C)on1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C25H32N4O8/c1-15-10-18(29-37-15)22(31)27-20(13-35-4)24(33)28-19(12-34-3)23(32)26-17(21(30)25(2)14-36-25)11-16-8-6-5-7-9-16/h5-10,17,19-20H,11-14H2,1-4H3,(H,26,32)(H,27,31)(H,28,33)/t17-,19-,20-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277815 (3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(OC)no1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C22H34N4O9/c1-12(2)7-13(18(27)22(3)11-34-22)23-19(28)14(9-31-4)24-20(29)15(10-32-5)25-21(30)16-8-17(33-6)26-35-16/h8,12-15H,7,9-11H2,1-6H3,(H,23,28)(H,24,29)(H,25,30)/t13-,14-,15-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277816 (3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(OC)no1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C25H32N4O9/c1-25(14-37-25)21(30)16(10-15-8-6-5-7-9-15)26-22(31)17(12-34-2)27-23(32)18(13-35-3)28-24(33)19-11-20(36-4)29-38-19/h5-9,11,16-18H,10,12-14H2,1-4H3,(H,26,31)(H,27,32)(H,28,33)/t16-,17-,18-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277780 (5-ethoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-...) Show SMILES CCOc1cc(no1)C(=O)N[C@@H](COC)C(=O)N[C@@H](COC)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C23H36N4O9/c1-7-34-18-9-15(27-36-18)20(29)25-17(11-33-6)22(31)26-16(10-32-5)21(30)24-14(8-13(2)3)19(28)23(4)12-35-23/h9,13-14,16-17H,7-8,10-12H2,1-6H3,(H,24,30)(H,25,29)(H,26,31)/t14-,16-,17-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277818 (2-Me-5-thiazole-Ser(OMe)-Ser(OMe)-Phe-ketoepoxide ...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cnc(C)o1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C25H32N4O8/c1-15-26-11-20(37-15)24(33)29-19(13-35-4)23(32)28-18(12-34-3)22(31)27-17(21(30)25(2)14-36-25)10-16-8-6-5-7-9-16/h5-9,11,17-19H,10,12-14H2,1-4H3,(H,27,31)(H,28,32)(H,29,33)/t17-,18-,19-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277778 (CHEMBL484002 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1ccon1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C24H30N4O8/c1-24(14-35-24)20(29)17(11-15-7-5-4-6-8-15)25-22(31)18(12-33-2)27-23(32)19(13-34-3)26-21(30)16-9-10-36-28-16/h4-10,17-19H,11-14H2,1-3H3,(H,25,31)(H,26,30)(H,27,32)/t17-,18-,19-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277733 ((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cc(C)on1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C22H34N4O8/c1-12(2)7-14(18(27)22(4)11-33-22)23-20(29)16(9-31-5)25-21(30)17(10-32-6)24-19(28)15-8-13(3)34-26-15/h8,12,14,16-17H,7,9-11H2,1-6H3,(H,23,29)(H,24,28)(H,25,30)/t14-,16-,17-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277734 (CHEMBL484157 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1ccon1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C21H32N4O8/c1-12(2)8-14(17(26)21(3)11-32-21)22-19(28)15(9-30-4)24-20(29)16(10-31-5)23-18(27)13-6-7-33-25-13/h6-7,12,14-16H,8-11H2,1-5H3,(H,22,28)(H,23,27)(H,24,29)/t14-,15-,16-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	607	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50277817 (CHEMBL483740 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...) Show SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1cnc(C)o1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C22H34N4O8/c1-12(2)7-14(18(27)22(4)11-33-22)24-19(28)15(9-31-5)25-20(29)16(10-32-6)26-21(30)17-8-23-13(3)34-17/h8,12,14-16H,7,9-11H2,1-6H3,(H,24,28)(H,25,29)(H,26,30)/t14-,15-,16-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	784	n/a	n/a	n/a	n/a	n/a	n/a
Proteolix, Inc. Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISA				J Med Chem 52: 3028-38 (2009) Article DOI: 10.1021/jm801329v BindingDB Entry DOI: 10.7270/Q2ZW1KS0
					More data for this Ligand-Target Pair