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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82141 (WIN 55212-2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | 7.30 | -46.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82135 (5-Substituted derivative, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.40 | -46.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82140 (4-methyl-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 15.7 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82139 (4-chloro-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 24.1 | -43.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82137 (4-methoxy-N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 42.6 | -42.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82138 (N-({1-[2-(morpholin-4-yl)ethyl]-1H-indol-3-yl}meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 49.4 | -41.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82136 (5-Substituted derivative, 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 69.6 | -40.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82132 (5-Substituted derivative, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 74.6 | -40.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82131 (3-(Arylimino)-1-(2-morpholin-4-yl-ethyl)-1,3-dihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 311 | -37.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82133 (5-Substituted derivative, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 390 | -36.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Cannabinoid receptor 1 (Rattus norvegicus (rat)) | BDBM82134 (3-(Arylimino)-1-(2-morpholin-4-yl-ethyl)-1,3-dihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 553 | -35.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Università di Napoli Federico II | Assay Description CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand. | Chem Biol Drug Des 75: 106-14 (2010) Article DOI: 10.1111/j.1747-0285.2009.00910.x BindingDB Entry DOI: 10.7270/Q2GM85SK | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Collagenase 3 (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-13 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage metalloelastase (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-12 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Collagenase 3 (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-13 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50427870 (CHEMBL2326364) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-2 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Collagenase 3 (Homo sapiens (Human)) | BDBM50427870 (CHEMBL2326364) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 386 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-13 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage metalloelastase (Homo sapiens (Human)) | BDBM50427870 (CHEMBL2326364) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-12 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage metalloelastase (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-12 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-14 (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric a... | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50427870 (CHEMBL2326364) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-9 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-14 (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric a... | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Matrix metalloproteinase-14 (Homo sapiens (Human)) | BDBM50427870 (CHEMBL2326364) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric a... | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interstitial collagenase (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-1 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Stromelysin-1 (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-3 (unknown origin) using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys-(Dnp)-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Stromelysin-1 (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-3 (unknown origin) using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys-(Dnp)-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interstitial collagenase (Homo sapiens (Human)) | BDBM50427870 (CHEMBL2326364) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-1 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Interstitial collagenase (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-1 (unknown origin) using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-2-microglobulin (Homo sapiens (Human)) | BDBM52947 ((2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.70E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Pavia | Assay Description Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay. | J Biol Chem 286: 2121-31 (2011) Article DOI: 10.1074/jbc.M110.178376 BindingDB Entry DOI: 10.7270/Q2542M6F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-2-microglobulin (Homo sapiens (Human)) | BDBM92397 (4-epi-oxytetracycline) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Pavia | Assay Description Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay. | J Biol Chem 286: 2121-31 (2011) Article DOI: 10.1074/jbc.M110.178376 BindingDB Entry DOI: 10.7270/Q2542M6F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-2-microglobulin (Homo sapiens (Human)) | BDBM37536 ((2E,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Pavia | Assay Description Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay. | J Biol Chem 286: 2121-31 (2011) Article DOI: 10.1074/jbc.M110.178376 BindingDB Entry DOI: 10.7270/Q2542M6F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Stromelysin-1 (Homo sapiens (Human)) | BDBM50427870 (CHEMBL2326364) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Inhibition of MMP-3 (unknown origin) using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys-(Dnp)-NH2 as substrate after 4 hrs by fluorometric assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-2-microglobulin (Homo sapiens (Human)) | BDBM55038 ((2E,4S,4aR,5S,5aR,12aS)-2-[amino(hydroxy)methylene...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Pavia | Assay Description Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay. | J Biol Chem 286: 2121-31 (2011) Article DOI: 10.1074/jbc.M110.178376 BindingDB Entry DOI: 10.7270/Q2542M6F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-2-microglobulin (Homo sapiens (Human)) | BDBM92395 (Meclocycline) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.80E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Pavia | Assay Description Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay. | J Biol Chem 286: 2121-31 (2011) Article DOI: 10.1074/jbc.M110.178376 BindingDB Entry DOI: 10.7270/Q2542M6F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-2-microglobulin (Homo sapiens (Human)) | BDBM92398 (Rolitetracycline) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.36E+5 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Pavia | Assay Description Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay. | J Biol Chem 286: 2121-31 (2011) Article DOI: 10.1074/jbc.M110.178376 BindingDB Entry DOI: 10.7270/Q2542M6F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Beta-2-microglobulin (Homo sapiens (Human)) | BDBM92399 (Anhydrochlortetracycline) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.36E+5 | n/a | n/a | n/a | n/a | 7.4 | 37 |
University of Pavia | Assay Description Inhibition of wild type beta-m fibrillogenesis tetracycline congeners and was follow by thioflavin fluorescence assay. | J Biol Chem 286: 2121-31 (2011) Article DOI: 10.1074/jbc.M110.178376 BindingDB Entry DOI: 10.7270/Q2542M6F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| 72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Binding affinity to MMP-2 (unknown origin) | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Albumin (Homo sapiens (Human)) | BDBM50427869 (CHEMBL2326365) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Binding affinity to human serum albumin by 19F NMR titration assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Albumin (Homo sapiens (Human)) | BDBM50427868 (CHEMBL2326366) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale"Amedeo Avogadro" Curated by ChEMBL | Assay Description Binding affinity to human serum albumin by 19F NMR titration assay | J Med Chem 56: 2676-89 (2013) Article DOI: 10.1021/jm4001743 BindingDB Entry DOI: 10.7270/Q2028SWH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
