Compile Data Set for Download or QSAR

Found 231 hits with Last Name = 'filzen' and Initial = 'gf'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347563 (CHEMBL1801740) Show SMILES CCc1nc2c(C)cc(CC(C)C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C29H31N7/c1-5-26-31-27-18(4)15-21(14-17(2)3)30-29(27)36(26)25-13-11-20-16-19(10-12-23(20)25)22-8-6-7-9-24(22)28-32-34-35-33-28/h6-10,12,15-17,25H,5,11,13-14H2,1-4H3,(H,32,33,34,35)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human Angiotensin receptor 1				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50347563 (CHEMBL1801740) Show SMILES CCc1nc2c(C)cc(CC(C)C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C29H31N7/c1-5-26-31-27-18(4)15-21(14-17(2)3)30-29(27)36(26)25-13-11-20-16-19(10-12-23(20)25)22-8-6-7-9-24(22)28-32-34-35-33-28/h6-10,12,15-17,25H,5,11,13-14H2,1-4H3,(H,32,33,34,35)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human Angiotensin receptor 2				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50043280 (4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...) Show SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)-c1nc2ccccc2n1C Show InChI InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382321 (CHEMBL2024688) Show SMILES Cc1cnn(c1-c1ccc2nc[nH]c(=O)c2c1)-c1cccc(C)n1 Show InChI InChI=1S/C18H15N5O/c1-11-9-21-23(16-5-3-4-12(2)22-16)17(11)13-6-7-15-14(8-13)18(24)20-10-19-15/h3-10H,1-2H3,(H,19,20,24)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382322 (CHEMBL2024689) Show SMILES CCc1cc(-c2ccc3ncn(C)c(=O)c3c2)n(n1)-c1cccc(C)n1 Show InChI InChI=1S/C20H19N5O/c1-4-15-11-18(25(23-15)19-7-5-6-13(2)22-19)14-8-9-17-16(10-14)20(26)24(3)12-21-17/h5-12H,4H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347563 (CHEMBL1801740) Show SMILES CCc1nc2c(C)cc(CC(C)C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C29H31N7/c1-5-26-31-27-18(4)15-21(14-17(2)3)30-29(27)36(26)25-13-11-20-16-19(10-12-23(20)25)22-8-6-7-9-24(22)28-32-34-35-33-28/h6-10,12,15-17,25H,5,11,13-14H2,1-4H3,(H,32,33,34,35)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50212698 (2-(7-(2-(4-(trifluoromethyl)benzyloxy)-5-fluoroben...) Show SMILES OC(=O)COc1ccc(SCc2cc(F)ccc2OCc2ccc(cc2)C(F)(F)F)c2CCCc12 Show InChI InChI=1S/C26H22F4O4S/c27-19-8-9-22(33-13-16-4-6-18(7-5-16)26(28,29)30)17(12-19)15-35-24-11-10-23(34-14-25(31)32)20-2-1-3-21(20)24/h4-12H,1-3,13-15H2,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assay				Bioorg Med Chem Lett 17: 3624-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.046 BindingDB Entry DOI: 10.7270/Q2S1826N
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50212693 (2-(4-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...) Show SMILES COc1cc(OCC(O)=O)c(C)cc1SCc1ccc(OCc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C25H23F3O5S/c1-16-11-23(22(31-2)12-21(16)33-14-24(29)30)34-15-18-5-9-20(10-6-18)32-13-17-3-7-19(8-4-17)25(26,27)28/h3-12H,13-15H2,1-2H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assay				Bioorg Med Chem Lett 17: 3624-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.046 BindingDB Entry DOI: 10.7270/Q2S1826N
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382324 (CHEMBL2024691) Show SMILES CCc1cnn(c1-c1ccc2nc[nH]c(=O)c2c1)-c1cccc(C)n1 Show InChI InChI=1S/C19H17N5O/c1-3-13-10-22-24(17-6-4-5-12(2)23-17)18(13)14-7-8-16-15(9-14)19(25)21-11-20-16/h4-11H,3H2,1-2H3,(H,20,21,25)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM28661 (2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...) Show SMILES Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50009718 (2-Ethyl-5,7-dimethyl-3-[2'-(1H-tetrazol-5-yl)-biph...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C24H23N7/c1-4-21-26-22-15(2)13-16(3)25-24(22)31(21)14-17-9-11-18(12-10-17)19-7-5-6-8-20(19)23-27-29-30-28-23/h5-13H,4,14H2,1-3H3,(H,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213331 (2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...) Show SMILES Cc1nc(sc1CSc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O2S2/c1-9-13(25-15(20-9)16(17,18)19)8-24-11-2-3-12-10(6-11)4-5-21(12)7-14(22)23/h2-6H,7-8H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382320 (CHEMBL2024687) Show SMILES Cc1cc(-c2ccc3ncn(C)c(=O)c3c2)n(n1)-c1cccc(C)n1 Show InChI InChI=1S/C19H17N5O/c1-12-5-4-6-18(21-12)24-17(9-13(2)22-24)14-7-8-16-15(10-14)19(25)23(3)11-20-16/h4-11H,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213326 (2-(6-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiaz...) Show SMILES Cc1nc(sc1COc1ccc2c(CC(O)=O)csc2c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H16F3NO3S2/c1-12-19(31-21(26-12)13-2-4-15(5-3-13)22(23,24)25)10-29-16-6-7-17-14(8-20(27)28)11-30-18(17)9-16/h2-7,9,11H,8,10H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347564 (CHEMBL1801741) Show SMILES CC(C)Cc1cc(C)c2nc(C(C)C)n([C@H]3CCc4cc(ccc34)-c3ccccc3-c3nnn[nH]3)c2n1 |r| Show InChI InChI=1S/C30H33N7/c1-17(2)14-22-15-19(5)27-30(31-22)37(29(32-27)18(3)4)26-13-11-21-16-20(10-12-24(21)26)23-8-6-7-9-25(23)28-33-35-36-34-28/h6-10,12,15-18,26H,11,13-14H2,1-5H3,(H,33,34,35,36)/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213330 (2-(6-(4-((4-(trifluoromethyl)phenoxy)methyl)benzyl...) Show SMILES OC(=O)Cc1csc2cc(OCc3ccc(COc4ccc(cc4)C(F)(F)F)cc3)ccc12 Show InChI InChI=1S/C25H19F3O4S/c26-25(27,28)19-5-7-20(8-6-19)31-13-16-1-3-17(4-2-16)14-32-21-9-10-22-18(11-24(29)30)15-33-23(22)12-21/h1-10,12,15H,11,13-14H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382318 (CHEMBL2024685) Show SMILES Cc1cccc(n1)-n1nccc1-c1ccc2ncn(C=C)c(=O)c2c1 Show InChI InChI=1S/C19H15N5O/c1-3-23-12-20-16-8-7-14(11-15(16)19(23)25)17-9-10-21-24(17)18-6-4-5-13(2)22-18/h3-12H,1H2,2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382319 (CHEMBL2024686) Show SMILES Cc1cnn(c1-c1ccc2ncn(C)c(=O)c2c1)-c1cccc(C)n1 Show InChI InChI=1S/C19H17N5O/c1-12-10-21-24(17-6-4-5-13(2)22-17)18(12)14-7-8-16-15(9-14)19(25)23(3)11-20-16/h4-11H,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50212693 (2-(4-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...) Show SMILES COc1cc(OCC(O)=O)c(C)cc1SCc1ccc(OCc2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C25H23F3O5S/c1-16-11-23(22(31-2)12-21(16)33-14-24(29)30)34-15-18-5-9-20(10-6-18)32-13-17-3-7-19(8-4-17)25(26,27)28/h3-12H,13-15H2,1-2H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA ass...				Bioorg Med Chem Lett 17: 3624-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.046 BindingDB Entry DOI: 10.7270/Q2S1826N
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382325 (CHEMBL2024693) Show SMILES Cc1cccc(n1)-n1nc2CCCc2c1-c1ccc2nc[nH]c(=O)c2c1 Show InChI InChI=1S/C20H17N5O/c1-12-4-2-7-18(23-12)25-19(14-5-3-6-17(14)24-25)13-8-9-16-15(10-13)20(26)22-11-21-16/h2,4,7-11H,3,5-6H2,1H3,(H,21,22,26)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347565 (CHEMBL1801743) Show SMILES CCc1nc2c(C)cc(Cc3ccccc3)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C32H29N7/c1-3-29-34-30-20(2)17-24(18-21-9-5-4-6-10-21)33-32(30)39(29)28-16-14-23-19-22(13-15-26(23)28)25-11-7-8-12-27(25)31-35-37-38-36-31/h4-13,15,17,19,28H,3,14,16,18H2,1-2H3,(H,35,36,37,38)/t28-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382323 (CHEMBL2024690) Show SMILES Cc1cccc(n1)-n1nccc1-c1ccc2nc[nH]c(=O)c2c1 Show InChI InChI=1S/C17H13N5O/c1-11-3-2-4-16(21-11)22-15(7-8-20-22)12-5-6-14-13(9-12)17(23)19-10-18-14/h2-10H,1H3,(H,18,19,23)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213313 (2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...) Show SMILES Cc1nc(sc1COc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O3S/c1-9-13(25-15(20-9)16(17,18)19)8-24-11-2-3-12-10(6-11)4-5-21(12)7-14(22)23/h2-6H,7-8H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347566 (CHEMBL1801738) Show SMILES CCc1nc2c(C)cc(CC)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C27H27N7/c1-4-19-14-16(3)25-27(28-19)34(24(5-2)29-25)23-13-11-18-15-17(10-12-21(18)23)20-8-6-7-9-22(20)26-30-32-33-31-26/h6-10,12,14-15,23H,4-5,11,13H2,1-3H3,(H,30,31,32,33)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347567 (CHEMBL1801712) Show SMILES CCc1nc2c(C)cc(C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C26H25N7/c1-4-23-28-24-15(2)13-16(3)27-26(24)33(23)22-12-10-18-14-17(9-11-20(18)22)19-7-5-6-8-21(19)25-29-31-32-30-25/h5-9,11,13-14,22H,4,10,12H2,1-3H3,(H,29,30,31,32)/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213321 (2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)ben...) Show SMILES OC(=O)Cc1csc2cc(OCc3cc(on3)-c3ccc(Cl)cc3)ccc12 Show InChI InChI=1S/C20H14ClNO4S/c21-14-3-1-12(2-4-14)18-8-15(22-26-18)10-25-16-5-6-17-13(7-20(23)24)11-27-19(17)9-16/h1-6,8-9,11H,7,10H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347568 (CHEMBL1801735) Show SMILES Cc1cc(C)c2nc(C3CC3)n([C@H]3CCc4cc(ccc34)-c3ccccc3-c3nnn[nH]3)c2n1 |r| Show InChI InChI=1S/C27H25N7/c1-15-13-16(2)28-27-24(15)29-26(17-7-8-17)34(27)23-12-10-19-14-18(9-11-21(19)23)20-5-3-4-6-22(20)25-30-32-33-31-25/h3-6,9,11,13-14,17,23H,7-8,10,12H2,1-2H3,(H,30,31,32,33)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50212708 (2-(7-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...) Show SMILES OC(=O)COc1ccc(SCc2ccc(OCc3ccc(cc3)C(F)(F)F)cc2)c2CCCc12 Show InChI InChI=1S/C26H23F3O4S/c27-26(28,29)19-8-4-17(5-9-19)14-32-20-10-6-18(7-11-20)16-34-24-13-12-23(33-15-25(30)31)21-2-1-3-22(21)24/h4-13H,1-3,14-16H2,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assay				Bioorg Med Chem Lett 17: 3624-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.046 BindingDB Entry DOI: 10.7270/Q2S1826N
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347569 (CHEMBL1801734) Show SMILES CC(C)c1nc2c(C)cc(C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C27H27N7/c1-15(2)26-29-24-16(3)13-17(4)28-27(24)34(26)23-12-10-19-14-18(9-11-21(19)23)20-7-5-6-8-22(20)25-30-32-33-31-25/h5-9,11,13-15,23H,10,12H2,1-4H3,(H,30,31,32,33)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50212696 (2-(7-(2-(4-(trifluoromethyl)benzyloxy)benzylthio)-...) Show SMILES OC(=O)COc1ccc(SCc2ccccc2OCc2ccc(cc2)C(F)(F)F)c2CCCc12 Show InChI InChI=1S/C26H23F3O4S/c27-26(28,29)19-10-8-17(9-11-19)14-32-22-7-2-1-4-18(22)16-34-24-13-12-23(33-15-25(30)31)20-5-3-6-21(20)24/h1-2,4,7-13H,3,5-6,14-16H2,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assay				Bioorg Med Chem Lett 17: 3624-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.046 BindingDB Entry DOI: 10.7270/Q2S1826N
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347570 (CHEMBL1801744) Show SMILES CCc1nc2c(C)cc(CC(C)C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1C(O)=O |r| Show InChI InChI=1S/C29H31N3O2/c1-5-26-31-27-18(4)15-21(14-17(2)3)30-28(27)32(26)25-13-11-20-16-19(10-12-23(20)25)22-8-6-7-9-24(22)29(33)34/h6-10,12,15-17,25H,5,11,13-14H2,1-4H3,(H,33,34)/t25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213315 (2-(6-((5-(4-(trifluoromethyl)phenyl)isoxazol-3-yl)...) Show SMILES OC(=O)Cc1csc2cc(OCc3cc(on3)-c3ccc(cc3)C(F)(F)F)ccc12 Show InChI InChI=1S/C21H14F3NO4S/c22-21(23,24)14-3-1-12(2-4-14)18-8-15(25-29-18)10-28-16-5-6-17-13(7-20(26)27)11-30-19(17)9-16/h1-6,8-9,11H,7,10H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213316 (2-(5-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...) Show SMILES OC(=O)Cn1ccc2cc(OCc3cccc(COc4ccc(cc4)C(F)(F)F)c3)ccc12 Show InChI InChI=1S/C25H20F3NO4/c26-25(27,28)20-4-6-21(7-5-20)32-15-17-2-1-3-18(12-17)16-33-22-8-9-23-19(13-22)10-11-29(23)14-24(30)31/h1-13H,14-16H2,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50382317 (CHEMBL2024684) Show SMILES Cc1cccc(n1)-n1nccc1-c1ccc2ncn(C)c(=O)c2c1 Show InChI InChI=1S/C18H15N5O/c1-12-4-3-5-17(21-12)23-16(8-9-20-23)13-6-7-15-14(10-13)18(24)22(2)11-19-15/h3-11H,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347571 (CHEMBL1801714) Show SMILES CCCc1nc2c(C)cc(C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C27H27N7/c1-4-7-24-29-25-16(2)14-17(3)28-27(25)34(24)23-13-11-19-15-18(10-12-21(19)23)20-8-5-6-9-22(20)26-30-32-33-31-26/h5-6,8-10,12,14-15,23H,4,7,11,13H2,1-3H3,(H,30,31,32,33)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213324 (2-(6-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiaz...) Show SMILES Cc1nc(sc1COc1ccc2c(CC(O)=O)coc2c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C22H16F3NO4S/c1-12-19(31-21(26-12)13-2-4-15(5-3-13)22(23,24)25)11-29-16-6-7-17-14(8-20(27)28)10-30-18(17)9-16/h2-7,9-10H,8,11H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213311 (2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...) Show SMILES OC(=O)Cc1csc2cc(OCc3cccc(COc4ccc(cc4)C(F)(F)F)c3)ccc12 Show InChI InChI=1S/C25H19F3O4S/c26-25(27,28)19-4-6-20(7-5-19)31-13-16-2-1-3-17(10-16)14-32-21-8-9-22-18(11-24(29)30)15-33-23(22)12-21/h1-10,12,15H,11,13-14H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347572 (CHEMBL1801737) Show SMILES CCc1nc2c(C)c(CC)c(C)nc2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1 |r| Show InChI InChI=1S/C28H29N7/c1-5-20-16(3)26-28(29-17(20)4)35(25(6-2)30-26)24-14-12-19-15-18(11-13-22(19)24)21-9-7-8-10-23(21)27-31-33-34-32-27/h7-11,13,15,24H,5-6,12,14H2,1-4H3,(H,31,32,33,34)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM50347573 (CHEMBL1801739) Show SMILES CCc1cc(C)c2nc(C(C)C)n([C@H]3CCc4cc(ccc34)-c3ccccc3-c3nnn[nH]3)c2n1 |r| Show InChI InChI=1S/C28H29N7/c1-5-20-14-17(4)25-28(29-20)35(27(30-25)16(2)3)24-13-11-19-15-18(10-12-22(19)24)21-8-6-7-9-23(21)26-31-33-34-32-26/h6-10,12,14-16,24H,5,11,13H2,1-4H3,(H,31,32,33,34)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16.9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after 60 mins by scintillation counting				J Med Chem 54: 4219-33 (2011) Article DOI: 10.1021/jm200409s BindingDB Entry DOI: 10.7270/Q2SB463J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50212707 (2-(4-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...) Show SMILES Cc1cc(SCc2ccc(OCc3ccc(cc3)C(F)(F)F)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C24H21F3O4S/c1-16-12-21(10-11-22(16)31-14-23(28)29)32-15-18-4-8-20(9-5-18)30-13-17-2-6-19(7-3-17)24(25,26)27/h2-12H,13-15H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assay				Bioorg Med Chem Lett 17: 3624-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.046 BindingDB Entry DOI: 10.7270/Q2S1826N
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50212701 (2-(4-(4-(4-(trifluoromethyl)benzyloxy)benzylthio)-...) Show SMILES Cc1cc(SCc2ccc(OCc3ccc(cc3)C(F)(F)F)cc2)c(Cl)cc1OCC(O)=O Show InChI InChI=1S/C24H20ClF3O4S/c1-15-10-22(20(25)11-21(15)32-13-23(29)30)33-14-17-4-8-19(9-5-17)31-12-16-2-6-18(7-3-16)24(26,27)28/h2-11H,12-14H2,1H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assay				Bioorg Med Chem Lett 17: 3624-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.046 BindingDB Entry DOI: 10.7270/Q2S1826N
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213309 (2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)-4-...) Show SMILES Cc1cc(OCc2cc(on2)-c2ccc(Cl)cc2)cc2scc(CC(O)=O)c12 Show InChI InChI=1S/C21H16ClNO4S/c1-12-6-17(9-19-21(12)14(11-28-19)7-20(24)25)26-10-16-8-18(27-23-16)13-2-4-15(22)5-3-13/h2-6,8-9,11H,7,10H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213317 (2-(6-(3-((4-(trifluoromethyl)phenoxy)methyl)benzyl...) Show SMILES OC(=O)Cc1coc2cc(OCc3cccc(COc4ccc(cc4)C(F)(F)F)c3)ccc12 Show InChI InChI=1S/C25H19F3O5/c26-25(27,28)19-4-6-20(7-5-19)31-13-16-2-1-3-17(10-16)14-32-21-8-9-22-18(11-24(29)30)15-33-23(22)12-21/h1-10,12,15H,11,13-14H2,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213325 (2-(6-((5-(4-(trifluoromethyl)phenyl)isoxazol-3-yl)...) Show SMILES OC(=O)Cc1coc2cc(OCc3cc(on3)-c3ccc(cc3)C(F)(F)F)ccc12 Show InChI InChI=1S/C21H14F3NO5/c22-21(23,24)14-3-1-12(2-4-14)18-8-15(25-30-18)11-28-16-5-6-17-13(7-20(26)27)10-29-19(17)9-16/h1-6,8-10H,7,11H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213320 (2-(5-((5-(4-(trifluoromethyl)phenyl)isoxazol-3-yl)...) Show SMILES OC(=O)Cn1ccc2cc(OCc3cc(on3)-c3ccc(cc3)C(F)(F)F)ccc12 Show InChI InChI=1S/C21H15F3N2O4/c22-21(23,24)15-3-1-13(2-4-15)19-10-16(25-30-19)12-29-17-5-6-18-14(9-17)7-8-26(18)11-20(27)28/h1-10H,11-12H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213318 (2-(6-((5-(4-chlorophenyl)isoxazol-3-yl)methoxy)-5-...) Show SMILES Cc1cc2c(CC(O)=O)csc2cc1OCc1cc(on1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H16ClNO4S/c1-12-6-17-14(7-21(24)25)11-28-20(17)9-18(12)26-10-16-8-19(27-23-16)13-2-4-15(22)5-3-13/h2-6,8-9,11H,7,10H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213328 (2-(4-methyl-6-((5-(4-(trifluoromethyl)phenyl)isoxa...) Show SMILES Cc1cc(OCc2cc(on2)-c2ccc(cc2)C(F)(F)F)cc2scc(CC(O)=O)c12 Show InChI InChI=1S/C22H16F3NO4S/c1-12-6-17(9-19-21(12)14(11-31-19)7-20(27)28)29-10-16-8-18(30-26-16)13-2-4-15(5-3-13)22(23,24)25/h2-6,8-9,11H,7,10H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50213310 (2-(6-(2-((4-(trifluoromethyl)phenoxy)methyl)benzyl...) Show SMILES Cc1cc2c(CC(O)=O)csc2cc1OCc1ccccc1COc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C26H21F3O4S/c1-16-10-22-19(11-25(30)31)15-34-24(22)12-23(16)33-14-18-5-3-2-4-17(18)13-32-21-8-6-20(7-9-21)26(27,28)29/h2-10,12,15H,11,13-14H2,1H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA				Bioorg Med Chem Lett 17: 3630-5 (2007) Article DOI: 10.1016/j.bmcl.2007.04.047 BindingDB Entry DOI: 10.7270/Q2ZK5GBB
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Mus musculus)	BDBM50382318 (CHEMBL2024685) Show SMILES Cc1cccc(n1)-n1nccc1-c1ccc2ncn(C=C)c(=O)c2c1 Show InChI InChI=1S/C19H15N5O/c1-3-23-12-20-16-8-7-14(11-15(16)19(23)25)17-9-10-21-24(17)18-6-4-5-13(2)22-18/h3-12H,1H2,2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assay				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Mus musculus)	BDBM50382325 (CHEMBL2024693) Show SMILES Cc1cccc(n1)-n1nc2CCCc2c1-c1ccc2nc[nH]c(=O)c2c1 Show InChI InChI=1S/C20H17N5O/c1-12-4-2-7-18(23-12)25-19(14-5-3-6-17(14)24-25)13-8-9-16-15(10-13)20(26)22-11-21-16/h2,4,7-11H,3,5-6H2,1H3,(H,21,22,26)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assay				Bioorg Med Chem Lett 22: 3392-7 (2012) Article DOI: 10.1016/j.bmcl.2012.04.013 BindingDB Entry DOI: 10.7270/Q2QC04H9
					More data for this Ligand-Target Pair

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