Found 485 hits with Last Name = 'harris' and Initial = 'nv' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012544
(CHEMBL3260768)Show SMILES Cc1oc(cc1CNc1ccc(cc1)-c1ccc(OC(F)F)cc1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C27H24F2N2O5S/c1-17-5-3-4-6-25(17)37(33,34)31-26(32)24-15-21(18(2)35-24)16-30-22-11-7-19(8-12-22)20-9-13-23(14-10-20)36-27(28)29/h3-15,27,30H,16H2,1-2H3,(H,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012543
(CHEMBL3260767)Show SMILES Cc1noc(C)c1S(=O)(=O)NC(=O)c1cc(COc2ccc(cc2)-c2ccc(OC(F)F)cc2)c(C)o1 Show InChI InChI=1S/C25H22F2N2O7S/c1-14-23(16(3)36-28-14)37(31,32)29-24(30)22-12-19(15(2)34-22)13-33-20-8-4-17(5-9-20)18-6-10-21(11-7-18)35-25(26)27/h4-12,25H,13H2,1-3H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012502
(CHEMBL3260457)Show SMILES Cc1oc(cc1COc1ccc(cc1)-c1ccc(OC(F)F)cc1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H21F2NO6S/c1-17-20(15-24(34-17)25(30)29-36(31,32)23-5-3-2-4-6-23)16-33-21-11-7-18(8-12-21)19-9-13-22(14-10-19)35-26(27)28/h2-15,26H,16H2,1H3,(H,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012532
(CHEMBL3260463)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2c(C)noc2C)cc1 Show InChI InChI=1S/C25H24N2O7S/c1-15-24(17(3)34-26-15)35(29,30)27-25(28)23-13-20(16(2)33-23)14-32-22-11-7-19(8-12-22)18-5-9-21(31-4)10-6-18/h5-13H,14H2,1-4H3,(H,27,28) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012542
(CHEMBL3260766)Show SMILES Cc1oc(cc1CNc1ccc(cc1)-c1ccccc1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C26H24N2O4S/c1-18-8-6-7-11-25(18)33(30,31)28-26(29)24-16-22(19(2)32-24)17-27-23-14-12-21(13-15-23)20-9-4-3-5-10-20/h3-16,27H,17H2,1-2H3,(H,28,29) | PDB
Reactome pathway
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PC sid
UniChem
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PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012534
(CHEMBL3260758)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)Cc2ccccc2)cc1 Show InChI InChI=1S/C27H25NO6S/c1-19-23(16-26(34-19)27(29)28-35(30,31)18-20-6-4-3-5-7-20)17-33-25-14-10-22(11-15-25)21-8-12-24(32-2)13-9-21/h3-16H,17-18H2,1-2H3,(H,28,29) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
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| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012548
(CHEMBL3260771)Show SMILES [Na+].COc1ccc(nc1)-c1ccc(OCc2cc(oc2C)C(=O)[N-]S(=O)(=O)c2ccccc2C)cc1 Show InChI InChI=1S/C26H24N2O6S.Na/c1-17-6-4-5-7-25(17)35(30,31)28-26(29)24-14-20(18(2)34-24)16-33-21-10-8-19(9-11-21)23-13-12-22(32-3)15-27-23;/h4-15H,16H2,1-3H3,(H,28,29);/q;+1/p-1 | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012545
(BGC-201531 | CHEMBL1628698)Show SMILES COc1ccc(nc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2C)cc1 Show InChI InChI=1S/C26H24N2O6S/c1-17-6-4-5-7-25(17)35(30,31)28-26(29)24-14-20(18(2)34-24)16-33-21-10-8-19(9-11-21)23-13-12-22(32-3)15-27-23/h4-15H,16H2,1-3H3,(H,28,29) | PDB
Reactome pathway
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CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012533
(CHEMBL3260757)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2cccs2)cc1 Show InChI InChI=1S/C24H21NO6S2/c1-16-19(14-22(31-16)24(26)25-33(27,28)23-4-3-13-32-23)15-30-21-11-7-18(8-12-21)17-5-9-20(29-2)10-6-17/h3-14H,15H2,1-2H3,(H,25,26) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012501
(CHEMBL3260456)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C26H23NO6S/c1-18-21(16-25(33-18)26(28)27-34(29,30)24-6-4-3-5-7-24)17-32-23-14-10-20(11-15-23)19-8-12-22(31-2)13-9-19/h3-16H,17H2,1-2H3,(H,27,28) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012530
(CHEMBL3260461)Show SMILES CCCS(=O)(=O)NC(=O)c1cc(COc2ccc(cc2)-c2ccc(OC)cc2)c(C)o1 Show InChI InChI=1S/C23H25NO6S/c1-4-13-31(26,27)24-23(25)22-14-19(16(2)30-22)15-29-21-11-7-18(8-12-21)17-5-9-20(28-3)10-6-17/h5-12,14H,4,13,15H2,1-3H3,(H,24,25) | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012549
(CHEMBL3260772)Show SMILES CC(C(=O)Nc1ccccc1Cc1ccccc1C(O)=O)c1cccc2ccccc12 Show InChI InChI=1S/C27H23NO3/c1-18(22-15-8-12-19-9-2-5-13-23(19)22)26(29)28-25-16-7-4-11-21(25)17-20-10-3-6-14-24(20)27(30)31/h2-16,18H,17H2,1H3,(H,28,29)(H,30,31) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012531
(CHEMBL3260462)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccc(O)cc2)cc1 Show InChI InChI=1S/C26H23NO7S/c1-17-20(15-25(34-17)26(29)27-35(30,31)24-13-7-21(28)8-14-24)16-33-23-11-5-19(6-12-23)18-3-9-22(32-2)10-4-18/h3-15,28H,16H2,1-2H3,(H,27,29) | PDB
Reactome pathway
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PC sid
UniChem
Similars
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012546
(CHEMBL3260769)Show SMILES COc1ccc(nc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2c(C)noc2C)cc1 Show InChI InChI=1S/C24H23N3O7S/c1-14-23(16(3)34-26-14)35(29,30)27-24(28)22-11-18(15(2)33-22)13-32-19-7-5-17(6-8-19)21-10-9-20(31-4)12-25-21/h5-12H,13H2,1-4H3,(H,27,28) | PDB
Reactome pathway
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PC sid
UniChem
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012541
(CHEMBL3260765)Show SMILES Cc1oc(cc1CNc1ccc(cc1)-c1ccccc1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C25H22N2O4S/c1-18-21(17-26-22-14-12-20(13-15-22)19-8-4-2-5-9-19)16-24(31-18)25(28)27-32(29,30)23-10-6-3-7-11-23/h2-16,26H,17H2,1H3,(H,27,28) | PDB
Reactome pathway
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UniChem
Similars
| Article
PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012539
(CHEMBL3260763)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccc(C)cn2)cc1 Show InChI InChI=1S/C26H24N2O6S/c1-17-4-13-25(27-15-17)35(30,31)28-26(29)24-14-21(18(2)34-24)16-33-23-11-7-20(8-12-23)19-5-9-22(32-3)10-6-19/h4-15H,16H2,1-3H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012486
(CHEMBL3260443)Show SMILES Cc1oc(cc1COc1ccc(cc1)-c1ccc(OC(F)F)cc1)C(O)=O Show InChI InChI=1S/C20H16F2O5/c1-12-15(10-18(26-12)19(23)24)11-25-16-6-2-13(3-7-16)14-4-8-17(9-5-14)27-20(21)22/h2-10,20H,11H2,1H3,(H,23,24) | PDB
Reactome pathway
KEGG
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012511
(CHEMBL3260459)Show SMILES CC(=O)c1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H23NO6S/c1-18(29)20-8-10-21(11-9-20)22-12-14-24(15-13-22)33-17-23-16-26(34-19(23)2)27(30)28-35(31,32)25-6-4-3-5-7-25/h3-16H,17H2,1-2H3,(H,28,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012535
(CHEMBL3260759)Show SMILES COc1ccc(c(C)c1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H25NO6S/c1-18-15-23(32-3)13-14-25(18)20-9-11-22(12-10-20)33-17-21-16-26(34-19(21)2)27(29)28-35(30,31)24-7-5-4-6-8-24/h4-16H,17H2,1-3H3,(H,28,29) | PDB
Reactome pathway
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UniChem
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PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012503
(CHEMBL3260458)Show SMILES COc1ccc(nc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C25H22N2O6S/c1-17-19(14-24(33-17)25(28)27-34(29,30)22-6-4-3-5-7-22)16-32-20-10-8-18(9-11-20)23-13-12-21(31-2)15-26-23/h3-15H,16H2,1-2H3,(H,27,28) | PDB
Reactome pathway
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PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012547
(CHEMBL3260770)Show SMILES COc1ccc(c(C)c1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2c(C)noc2C)cc1 Show InChI InChI=1S/C26H26N2O7S/c1-15-12-22(32-5)10-11-23(15)19-6-8-21(9-7-19)33-14-20-13-24(34-17(20)3)26(29)28-36(30,31)25-16(2)27-35-18(25)4/h6-13H,14H2,1-5H3,(H,28,29) | PDB
Reactome pathway
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UniChem
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PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012500
(CHEMBL3260455)Show SMILES Cc1oc(cc1COc1ccc(cc1)-c1ccccc1)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C25H21NO5S/c1-18-21(17-30-22-14-12-20(13-15-22)19-8-4-2-5-9-19)16-24(31-18)25(27)26-32(28,29)23-10-6-3-7-11-23/h2-16H,17H2,1H3,(H,26,27) | PDB
Reactome pathway
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PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012324
(CHEMBL3260430)Show InChI InChI=1S/C20H18O4/c1-14-17(11-19(24-14)12-20(21)22)13-23-18-9-7-16(8-10-18)15-5-3-2-4-6-15/h2-11H,12-13H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012325
(CHEMBL3260431)Show InChI InChI=1S/C21H20O4/c1-15-18(13-20(25-15)11-12-21(22)23)14-24-19-9-7-17(8-10-19)16-5-3-2-4-6-16/h2-10,13H,11-12,14H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
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UniChem
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PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012536
(CHEMBL3260760)Show SMILES COc1ccccc1-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C26H23NO6S/c1-18-20(16-25(33-18)26(28)27-34(29,30)22-8-4-3-5-9-22)17-32-21-14-12-19(13-15-21)23-10-6-7-11-24(23)31-2/h3-16H,17H2,1-2H3,(H,27,28) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012480
(CHEMBL3260437)Show InChI InChI=1S/C20H18O5/c1-13-16(11-19(25-13)20(21)22)12-24-18-9-5-15(6-10-18)14-3-7-17(23-2)8-4-14/h3-11H,12H2,1-2H3,(H,21,22) | PDB
Reactome pathway
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UniChem
Similars
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PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012537
(CHEMBL3260761)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)c2ccc(CN)cc2)cc1 Show InChI InChI=1S/C27H26N2O6S/c1-18-22(17-34-24-11-7-21(8-12-24)20-5-9-23(33-2)10-6-20)15-26(35-18)27(30)29-36(31,32)25-13-3-19(16-28)4-14-25/h3-15H,16-17,28H2,1-2H3,(H,29,30) | PDB
Reactome pathway
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UniChem
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| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012538
(CHEMBL3260762)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)N(C)C)cc1 Show InChI InChI=1S/C22H24N2O6S/c1-15-18(13-21(30-15)22(25)23-31(26,27)24(2)3)14-29-20-11-7-17(8-12-20)16-5-9-19(28-4)10-6-16/h5-13H,14H2,1-4H3,(H,23,25) | PDB
Reactome pathway
KEGG
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UniChem
Similars
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PubMed
| 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012489
(CHEMBL3260446)Show SMILES CC(=O)c1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(O)=O)cc1 Show InChI InChI=1S/C21H18O5/c1-13(22)15-3-5-16(6-4-15)17-7-9-19(10-8-17)25-12-18-11-20(21(23)24)26-14(18)2/h3-11H,12H2,1-2H3,(H,23,24) | PDB
Reactome pathway
KEGG
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UniChem
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| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012529
(CHEMBL3260460)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(C)(=O)=O)cc1 Show InChI InChI=1S/C21H21NO6S/c1-14-17(12-20(28-14)21(23)22-29(3,24)25)13-27-19-10-6-16(7-11-19)15-4-8-18(26-2)9-5-15/h4-12H,13H2,1-3H3,(H,22,23) | PDB
Reactome pathway
KEGG
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UniChem
Similars
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PubMed
| 218 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012550
(CHEMBL3260419)Show InChI InChI=1S/C19H16O4/c1-13-16(11-18(23-13)19(20)21)12-22-17-9-7-15(8-10-17)14-5-3-2-4-6-14/h2-11H,12H2,1H3,(H,20,21) | PDB
Reactome pathway
KEGG
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
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PubMed
| 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012484
(CHEMBL3260441)Show InChI InChI=1S/C20H16O6/c1-12-15(9-19(26-12)20(21)22)10-23-16-5-2-13(3-6-16)14-4-7-17-18(8-14)25-11-24-17/h2-9H,10-11H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
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UniChem
Similars
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PubMed
| 600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012481
(CHEMBL3260438)Show InChI InChI=1S/C20H18O5/c1-13-16(11-19(25-13)20(21)22)12-24-17-8-6-14(7-9-17)15-4-3-5-18(10-15)23-2/h3-11H,12H2,1-2H3,(H,21,22) | PDB
Reactome pathway
KEGG
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UniChem
Similars
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PubMed
| 740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012487
(CHEMBL3260444)Show InChI InChI=1S/C19H15ClO4/c1-12-15(10-18(24-12)19(21)22)11-23-17-8-4-14(5-9-17)13-2-6-16(20)7-3-13/h2-10H,11H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
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PC sid
UniChem
Similars
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PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012540
(CHEMBL3260764)Show SMILES COc1ccc(cc1)-c1ccc(OCc2cc(oc2C)C(=O)NS(=O)(=O)CCCN2CCOCC2)cc1 Show InChI InChI=1S/C27H32N2O7S/c1-20-23(19-35-25-10-6-22(7-11-25)21-4-8-24(33-2)9-5-21)18-26(36-20)27(30)28-37(31,32)17-3-12-29-13-15-34-16-14-29/h4-11,18H,3,12-17,19H2,1-2H3,(H,28,30) | PDB
Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012499
(CHEMBL3260454)Show InChI InChI=1S/C19H17NO5/c1-12-14(9-18(25-12)19(21)22)11-24-15-5-3-13(4-6-15)17-8-7-16(23-2)10-20-17/h3-10H,11H2,1-2H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012559
(CHEMBL3260429)Show SMILES OC(=O)c1cc(COc2ccc(cc2)-c2ccccc2)c(o1)C(F)(F)F Show InChI InChI=1S/C19H13F3O4/c20-19(21,22)17-14(10-16(26-17)18(23)24)11-25-15-8-6-13(7-9-15)12-4-2-1-3-5-12/h1-10H,11H2,(H,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012355
(CHEMBL3260434)Show InChI InChI=1S/C18H15NO3/c1-12-16(11-17(22-12)18(20)21)19-15-9-7-14(8-10-15)13-5-3-2-4-6-13/h2-11,19H,1H3,(H,20,21) | PDB
Reactome pathway
KEGG
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012488
(CHEMBL3260445)Show InChI InChI=1S/C20H15NO4/c1-13-17(10-19(25-13)20(22)23)12-24-18-8-6-16(7-9-18)15-4-2-14(11-21)3-5-15/h2-10H,12H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012482
(CHEMBL3260439)Show InChI InChI=1S/C20H18O5/c1-13-15(11-19(25-13)20(21)22)12-24-16-9-7-14(8-10-16)17-5-3-4-6-18(17)23-2/h3-11H,12H2,1-2H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012557
(CHEMBL3260427)Show InChI InChI=1S/C18H14O4/c19-18(20)17-10-13(12-22-17)11-21-16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-10,12H,11H2,(H,19,20) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012485
(CHEMBL3260442)Show SMILES Cc1oc(cc1COc1ccc(cc1)-c1ccc(OC(F)(F)F)cc1)C(O)=O Show InChI InChI=1S/C20H15F3O5/c1-12-15(10-18(27-12)19(24)25)11-26-16-6-2-13(3-7-16)14-4-8-17(9-5-14)28-20(21,22)23/h2-10H,11H2,1H3,(H,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012483
(CHEMBL3260440)Show SMILES COc1ccc(cc1OC)-c1ccc(OCc2cc(oc2C)C(O)=O)cc1 Show InChI InChI=1S/C21H20O6/c1-13-16(11-20(27-13)21(22)23)12-26-17-7-4-14(5-8-17)15-6-9-18(24-2)19(10-15)25-3/h4-11H,12H2,1-3H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012479
(CHEMBL3260436)Show InChI InChI=1S/C20H18O5/c1-13-17(10-19(25-13)20(22)23)12-24-18-8-6-16(7-9-18)15-4-2-14(11-21)3-5-15/h2-10,21H,11-12H2,1H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012558
(CHEMBL3260428)Show InChI InChI=1S/C21H20O4/c1-14(2)20-17(12-19(25-20)21(22)23)13-24-18-10-8-16(9-11-18)15-6-4-3-5-7-15/h3-12,14H,13H2,1-2H3,(H,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012326
(CHEMBL3260432)Show InChI InChI=1S/C20H18O4/c1-14-17(13-19(24-14)20(21)22)11-12-23-18-9-7-16(8-10-18)15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012494
(CHEMBL3260450)Show InChI InChI=1S/C15H12N2O4S/c1-9-11(6-14(21-9)15(18)19)7-20-12-4-2-10(3-5-12)13-8-22-17-16-13/h2-6,8H,7H2,1H3,(H,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012478
(CHEMBL3260435)Show InChI InChI=1S/C19H16O5/c1-12-15(10-18(24-12)19(21)22)11-23-17-8-4-14(5-9-17)13-2-6-16(20)7-3-13/h2-10,20H,11H2,1H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012493
(CHEMBL3260449)Show SMILES Cc1oc(cc1COc1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(O)=O Show InChI InChI=1S/C20H18O6S/c1-13-16(11-19(26-13)20(21)22)12-25-17-7-3-14(4-8-17)15-5-9-18(10-6-15)27(2,23)24/h3-11H,12H2,1-2H3,(H,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50012495
(CHEMBL3260451)Show InChI InChI=1S/C15H12N2O5/c1-9-11(6-13(22-9)15(18)19)7-20-12-4-2-10(3-5-12)14-17-16-8-21-14/h2-6,8H,7H2,1H3,(H,18,19) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Argenta Discovery Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting |
Bioorg Med Chem Lett 24: 2212-21 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.068
BindingDB Entry DOI: 10.7270/Q2125V6J |
More data for this
Ligand-Target Pair | |
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