Compile Data Set for Download or QSAR

Found 153 hits with Last Name = 'henley' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28030 (2-aminopyridine analogue, 9 | N-{4-[(2-amino-3-chl...) Show SMILES Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c1Cl Show InChI InChI=1S/C23H15ClF2N4O3/c24-20-19(9-10-28-21(20)27)33-18-8-5-14(12-17(18)26)29-22(31)16-2-1-11-30(23(16)32)15-6-3-13(25)4-7-15/h1-12H,(H2,27,28)(H,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28028 (2-aminopyridine analogue, 7 | N-{4-[(2-amino-3-eth...) Show SMILES Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c1C#C Show InChI InChI=1S/C25H16F2N4O3/c1-2-18-21(11-12-29-23(18)28)34-22-10-7-16(14-20(22)27)30-24(32)19-4-3-13-31(25(19)33)17-8-5-15(26)6-9-17/h1,3-14H,(H2,28,29)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24457 (2-[(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}p...) Show SMILES [O-][n+]1c(cccc1-c1ccccc1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 Show InChI InChI=1S/C25H17FN4O3/c26-19-15-17(9-10-23(19)33-22-12-14-28-24-18(22)11-13-27-24)29-25(31)21-8-4-7-20(30(21)32)16-5-2-1-3-6-16/h1-15H,(H,27,28)(H,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24440 (2-pyridone analogue, 2 | JMC521251 Compound 1 | N-...) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c1=O Show InChI InChI=1S/C25H16F2N4O3/c26-15-3-6-17(7-4-15)31-13-1-2-19(25(31)33)24(32)30-16-5-8-22(20(27)14-16)34-21-10-12-29-23-18(21)9-11-28-23/h1-14H,(H,28,29)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24458 (2-[(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}p...) Show SMILES [O-][n+]1c(cccc1-c1ccc(F)cc1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 Show InChI InChI=1S/C25H16F2N4O3/c26-16-6-4-15(5-7-16)20-2-1-3-21(31(20)33)25(32)30-17-8-9-23(19(27)14-17)34-22-11-13-29-24-18(22)10-12-28-24/h1-14H,(H,28,29)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24440 (2-pyridone analogue, 2 | JMC521251 Compound 1 | N-...) Show SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c1=O Show InChI InChI=1S/C25H16F2N4O3/c26-15-3-6-17(7-4-15)31-13-1-2-19(25(31)33)24(32)30-16-5-8-22(20(27)14-16)34-21-10-12-29-23-18(21)9-11-28-23/h1-14H,(H,28,29)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24441 (2-pyridone analogue, 13 | N-(3-fluoro-4-{1H-pyrrol...) Show SMILES Fc1cc(NC(=O)c2cccn(-c3ccccc3)c2=O)ccc1Oc1ccnc2[nH]ccc12 Show InChI InChI=1S/C25H17FN4O3/c26-20-15-16(8-9-22(20)33-21-11-13-28-23-18(21)10-12-27-23)29-24(31)19-7-4-14-30(25(19)32)17-5-2-1-3-6-17/h1-15H,(H,27,28)(H,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24454 (1-(3-fluoro-4-methoxyphenyl)-N-(3-fluoro-4-{1H-pyr...) Show SMILES COc1ccc(cc1F)-n1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(=O)c(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C32H21F3N4O4/c1-42-28-9-7-21(15-26(28)35)39-16-23(18-2-4-19(33)5-3-18)30(40)24(17-39)32(41)38-20-6-8-29(25(34)14-20)43-27-11-13-37-31-22(27)10-12-36-31/h2-17H,1H3,(H,36,37)(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28033 (2-aminopyridine analogue, 12 | N-{4-[(2-amino-3-ch...) Show SMILES Nc1nccc(Oc2ccc(NC(=O)c3c(OCCO)ccn(-c4ccc(F)cc4)c3=O)cc2F)c1Cl Show InChI InChI=1S/C25H19ClF2N4O5/c26-22-20(7-9-30-23(22)29)37-18-6-3-15(13-17(18)28)31-24(34)21-19(36-12-11-33)8-10-32(25(21)35)16-4-1-14(27)2-5-16/h1-10,13,33H,11-12H2,(H2,29,30)(H,31,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28026 (2-aminopyridine analogue, 5 | N-(4-{[2-amino-3-(3-...) Show SMILES Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c1C#CCO Show InChI InChI=1S/C26H18F2N4O4/c27-16-5-8-18(9-6-16)32-13-1-3-20(26(32)35)25(34)31-17-7-10-23(21(28)15-17)36-22-11-12-30-24(29)19(22)4-2-14-33/h1,3,5-13,15,33H,14H2,(H2,29,30)(H,31,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24449 (4-pyridone analogue, 3 | N-(3-fluoro-4-{1H-pyrrolo...) Show SMILES Oc1c(cncc1-c1ccc(F)cc1)C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 Show InChI InChI=1S/C25H16F2N4O3/c26-15-3-1-14(2-4-15)18-12-28-13-19(23(18)32)25(33)31-16-5-6-22(20(27)11-16)34-21-8-10-30-24-17(21)7-9-29-24/h1-13H,(H,28,32)(H,29,30)(H,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24450 (4-pyridone analogue, 34 | N-(3-fluoro-4-{1H-pyrrol...) Show SMILES Cn1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(=O)c(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C26H18F2N4O3/c1-32-13-19(15-2-4-16(27)5-3-15)24(33)20(14-32)26(34)31-17-6-7-23(21(28)12-17)35-22-9-11-30-25-18(22)8-10-29-25/h2-14H,1H3,(H,29,30)(H,31,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28032 (2-aminopyridine analogue, 11 | N-{4-[(2-amino-3-ch...) Show SMILES CC(C)Oc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc(N)c2Cl)c(F)c1 Show InChI InChI=1S/C26H21ClF2N4O4/c1-14(2)36-20-10-12-33(17-6-3-15(28)4-7-17)26(35)22(20)25(34)32-16-5-8-19(18(29)13-16)37-21-9-11-31-24(30)23(21)27/h3-14H,1-2H3,(H2,30,31)(H,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24452 (1-cyclopropyl-N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyri...) Show SMILES Fc1ccc(cc1)-c1cn(cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c1=O)C1CC1 Show InChI InChI=1S/C28H20F2N4O3/c29-17-3-1-16(2-4-17)21-14-34(19-6-7-19)15-22(26(21)35)28(36)33-18-5-8-25(23(30)13-18)37-24-10-12-32-27-20(24)9-11-31-27/h1-5,8-15,19H,6-7H2,(H,31,32)(H,33,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28027 (2-aminopyridine analogue, 6 | N-(4-{[2-amino-3-(hy...) Show SMILES Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c1CO Show InChI InChI=1S/C24H18F2N4O4/c25-14-3-6-16(7-4-14)30-11-1-2-17(24(30)33)23(32)29-15-5-8-21(19(26)12-15)34-20-9-10-28-22(27)18(20)13-31/h1-12,31H,13H2,(H2,27,28)(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28029 (2-aminopyridine analogue, 8 | N-(4-{[2-amino-3-(pr...) Show SMILES CC(C)c1c(N)nccc1Oc1ccc(NC(=O)c2cccn(-c3ccc(F)cc3)c2=O)cc1F Show InChI InChI=1S/C26H22F2N4O3/c1-15(2)23-22(11-12-30-24(23)29)35-21-10-7-17(14-20(21)28)31-25(33)19-4-3-13-32(26(19)34)18-8-5-16(27)6-9-18/h3-15H,1-2H3,(H2,29,30)(H,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28025 (2-aminopyridine analogue, 4 | N-(4-{[2-amino-3-(3-...) Show SMILES NCC#Cc1c(N)nccc1Oc1ccc(NC(=O)c2cccn(-c3ccc(F)cc3)c2=O)cc1F Show InChI InChI=1S/C26H19F2N5O3/c27-16-5-8-18(9-6-16)33-14-2-4-20(26(33)35)25(34)32-17-7-10-23(21(28)15-17)36-22-11-13-31-24(30)19(22)3-1-12-29/h2,4-11,13-15H,12,29H2,(H2,30,31)(H,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24451 (4-pyridone analogue, 37 | N-(3-fluoro-4-{1H-pyrrol...) Show SMILES OCCn1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(=O)c(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H20F2N4O4/c28-17-3-1-16(2-4-17)20-14-33(11-12-34)15-21(25(20)35)27(36)32-18-5-6-24(22(29)13-18)37-23-8-10-31-26-19(23)7-9-30-26/h1-10,13-15,34H,11-12H2,(H,30,31)(H,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28031 (BMS-777607 | N-{4-[(2-amino-3-chloropyridin-4-yl)o...) Show SMILES CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc(N)c2Cl)c(F)c1 Show InChI InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28023 (N-{4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}-1-...) Show SMILES Nc1cc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)ccn1 Show InChI InChI=1S/C23H16F2N4O3/c24-14-3-6-16(7-4-14)29-11-1-2-18(23(29)31)22(30)28-15-5-8-20(19(25)12-15)32-17-9-10-27-21(26)13-17/h1-13H,(H2,26,27)(H,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24453 (1-(4-chloro-3-fluorophenyl)-N-(3-fluoro-4-{1H-pyrr...) Show SMILES Fc1ccc(cc1)-c1cn(cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c1=O)-c1ccc(Cl)c(F)c1 Show InChI InChI=1S/C31H18ClF3N4O3/c32-24-7-6-20(14-25(24)34)39-15-22(17-1-3-18(33)4-2-17)29(40)23(16-39)31(41)38-19-5-8-28(26(35)13-19)42-27-10-12-37-30-21(27)9-11-36-30/h1-16H,(H,36,37)(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM28024 (2-aminopyridine analogue, 3 | N-[4-({2-amino-3-[(4...) Show SMILES CN1CCN(Cc2c(N)nccc2Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)CC1 Show InChI InChI=1S/C29H28F2N6O3/c1-35-13-15-36(16-14-35)18-23-25(10-11-33-27(23)32)40-26-9-6-20(17-24(26)31)34-28(38)22-3-2-12-37(29(22)39)21-7-4-19(30)5-8-21/h2-12,17H,13-16,18H2,1H3,(H2,32,33)(H,34,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate in the presence of test compound. Dose response c...				J Med Chem 52: 1251-4 (2009) Article DOI: 10.1021/jm801586s BindingDB Entry DOI: 10.7270/Q20863MZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317751 (2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...) Show SMILES Cc1ccccc1NC(=O)c1cccnc1Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 Show InChI InChI=1S/C26H20FN5O2/c1-16-5-2-3-7-21(16)32-26(33)19-6-4-12-28-25(19)31-17-8-9-23(20(27)15-17)34-22-11-14-30-24-18(22)10-13-29-24/h2-15H,1H3,(H,28,31)(H,29,30)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317750 (2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...) Show SMILES Fc1ccc(NC(=O)c2cccnc2Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(F)c1 Show InChI InChI=1S/C25H16F3N5O2/c26-14-3-5-20(18(27)12-14)33-25(34)17-2-1-9-29-24(17)32-15-4-6-22(19(28)13-15)35-21-8-11-31-23-16(21)7-10-30-23/h1-13H,(H,29,32)(H,30,31)(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317749 (2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)...) Show SMILES Nc1cc(Oc2ccc(Nc3ncccc3C(=O)Nc3ccc(F)cc3F)cc2F)ccn1 Show InChI InChI=1S/C23H16F3N5O2/c24-13-3-5-19(17(25)10-13)31-23(32)16-2-1-8-29-22(16)30-14-4-6-20(18(26)11-14)33-15-7-9-28-21(27)12-15/h1-12H,(H2,27,28)(H,29,30)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24445 (2-pyridone analogue, 17 | N-(3-fluoro-4-{1H-pyrrol...) Show SMILES Fc1ccc(Cn2cccc(C(=O)Nc3ccc(Oc4ccnc5[nH]ccc45)c(F)c3)c2=O)cc1 Show InChI InChI=1S/C26H18F2N4O3/c27-17-5-3-16(4-6-17)15-32-13-1-2-20(26(32)34)25(33)31-18-7-8-23(21(28)14-18)35-22-10-12-30-24-19(22)9-11-29-24/h1-14H,15H2,(H,29,30)(H,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317759 (2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...) Show SMILES Fc1ccc(NC(=O)c2cc(Br)cnc2Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(F)c1 Show InChI InChI=1S/C25H15BrF3N5O2/c26-13-9-17(25(35)34-20-3-1-14(27)10-18(20)28)24(32-12-13)33-15-2-4-22(19(29)11-15)36-21-6-8-31-23-16(21)5-7-30-23/h1-12H,(H,30,31)(H,32,33)(H,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317756 (2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...) Show SMILES OCCc1ccccc1NC(=O)c1cccnc1Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 Show InChI InChI=1S/C27H22FN5O3/c28-21-16-18(7-8-24(21)36-23-10-14-31-25-19(23)9-13-30-25)32-26-20(5-3-12-29-26)27(35)33-22-6-2-1-4-17(22)11-15-34/h1-10,12-14,16,34H,11,15H2,(H,29,32)(H,30,31)(H,33,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317765 (4-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)...) Show SMILES CSc1ncc(C(=O)Nc2ccc(F)cc2F)c(Nc2ccc(Oc3ccnc(N)c3)c(F)c2)n1 Show InChI InChI=1S/C23H17F3N6O2S/c1-35-23-29-11-15(22(33)31-18-4-2-12(24)8-16(18)25)21(32-23)30-13-3-5-19(17(26)9-13)34-14-6-7-28-20(27)10-14/h2-11H,1H3,(H2,27,28)(H,31,33)(H,29,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374709 (CHEMBL271864) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(o1)N1CCC(N)CC1 Show InChI InChI=1S/C26H29F2N9O2/c1-13(2)21-17(25-34-35-26(39-25)36-7-5-14(29)6-8-36)11-37-22(21)23(30-12-31-37)33-20-9-16(18(27)10-19(20)28)24(38)32-15-3-4-15/h9-15H,3-8,29H2,1-2H3,(H,32,38)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM24446 (2-pyridone analogue, 18 | N-(3-fluoro-4-{1H-pyrrol...) Show SMILES Fc1cc(NC(=O)c2cccn(-c3ccccn3)c2=O)ccc1Oc1ccnc2[nH]ccc12 Show InChI InChI=1S/C24H16FN5O3/c25-18-14-15(6-7-20(18)33-19-9-12-28-22-16(19)8-11-27-22)29-23(31)17-4-3-13-30(24(17)32)21-5-1-2-10-26-21/h1-14H,(H,27,28)(H,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	30
Bristol-Myers Squibb Company					Assay Description Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...				J Med Chem 51: 5330-41 (2008) Article DOI: 10.1021/jm800476q BindingDB Entry DOI: 10.7270/Q2K35RZG
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374697 (CHEMBL258046) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(OC2CCNCC2)o1 Show InChI InChI=1S/C26H28F2N8O3/c1-13(2)21-17(25-34-35-26(39-25)38-15-5-7-29-8-6-15)11-36-22(21)23(30-12-31-36)33-20-9-16(18(27)10-19(20)28)24(37)32-14-3-4-14/h9-15,29H,3-8H2,1-2H3,(H,32,37)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317748 (2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)...) Show SMILES Nc1cc(Oc2ccc(Nc3ncccc3C(=O)Nc3ccc(Cl)cc3)cc2F)ccn1 Show InChI InChI=1S/C23H17ClFN5O2/c24-14-3-5-15(6-4-14)30-23(31)18-2-1-10-28-22(18)29-16-7-8-20(19(25)12-16)32-17-9-11-27-21(26)13-17/h1-13H,(H2,26,27)(H,28,29)(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374717 (CHEMBL271310) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(NCCCN(C)C)o1 Show InChI InChI=1S/C26H31F2N9O2/c1-14(2)21-17(25-34-35-26(39-25)29-8-5-9-36(3)4)12-37-22(21)23(30-13-31-37)33-20-10-16(18(27)11-19(20)28)24(38)32-15-6-7-15/h10-15H,5-9H2,1-4H3,(H,29,35)(H,32,38)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50377356 (CHEMBL410686) Show SMILES CC(C)c1c(cn2ncnc(Nc3cnc4[nH]c(C)cc4c3F)c12)-c1nnc(C)o1 Show InChI InChI=1S/C20H19FN8O/c1-9(2)15-13(20-28-27-11(4)30-20)7-29-17(15)19(23-8-24-29)26-14-6-22-18-12(16(14)21)5-10(3)25-18/h5-9H,1-4H3,(H,22,25)(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem Lett 18: 2985-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.057 BindingDB Entry DOI: 10.7270/Q28053HZ
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317758 (2-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)...) Show SMILES Nc1cc(Oc2ccc(Nc3ncc(Br)cc3C(=O)Nc3ccc(F)cc3F)cc2F)ccn1 Show InChI InChI=1S/C23H15BrF3N5O2/c24-12-7-16(23(33)32-19-3-1-13(25)8-17(19)26)22(30-11-12)31-14-2-4-20(18(27)9-14)34-15-5-6-29-21(28)10-15/h1-11H,(H2,28,29)(H,30,31)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374698 (CHEMBL270193) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(NCCCCN)o1 Show InChI InChI=1S/C25H29F2N9O2/c1-13(2)20-16(24-34-35-25(38-24)29-8-4-3-7-28)11-36-21(20)22(30-12-31-36)33-19-9-15(17(26)10-18(19)27)23(37)32-14-5-6-14/h9-14H,3-8,28H2,1-2H3,(H,29,35)(H,32,37)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374710 (CHEMBL271512) Show SMILES CNCCCNc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C25H29F2N9O2/c1-13(2)20-16(24-34-35-25(38-24)29-8-4-7-28-3)11-36-21(20)22(30-12-31-36)33-19-9-15(17(26)10-18(19)27)23(37)32-14-5-6-14/h9-14,28H,4-8H2,1-3H3,(H,29,35)(H,32,37)(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374711 (CHEMBL402319) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(NCCCN)o1 Show InChI InChI=1S/C24H27F2N9O2/c1-12(2)19-15(23-33-34-24(37-23)28-7-3-6-27)10-35-20(19)21(29-11-30-35)32-18-8-14(16(25)9-17(18)26)22(36)31-13-4-5-13/h8-13H,3-7,27H2,1-2H3,(H,28,34)(H,31,36)(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50377361 (CHEMBL409673) Show SMILES COC(=O)c1cn2ncnc(Nc3cnc4[nH]ccc4c3)c2c1C(C)C Show InChI InChI=1S/C18H18N6O2/c1-10(2)14-13(18(25)26-3)8-24-15(14)17(21-9-22-24)23-12-6-11-4-5-19-16(11)20-7-12/h4-10H,1-3H3,(H,19,20)(H,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem Lett 18: 2985-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.057 BindingDB Entry DOI: 10.7270/Q28053HZ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374715 (CHEMBL407944) Show SMILES CCCNc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C24H26F2N8O2/c1-4-7-27-24-33-32-23(36-24)15-10-34-20(19(15)12(2)3)21(28-11-29-34)31-18-8-14(16(25)9-17(18)26)22(35)30-13-5-6-13/h8-13H,4-7H2,1-3H3,(H,27,33)(H,30,35)(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317757 (2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...) Show SMILES Cc1ccc(C(=O)Nc2ccc(F)cc2F)c(Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)n1 Show InChI InChI=1S/C26H18F3N5O2/c1-14-2-5-18(26(35)34-21-6-3-15(27)12-19(21)28)25(32-14)33-16-4-7-23(20(29)13-16)36-22-9-11-31-24-17(22)8-10-30-24/h2-13H,1H3,(H,30,31)(H,32,33)(H,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50377367 (CHEMBL256116) Show SMILES C[C@@H](O)COc1cn2ncnc(Oc3cnc4[nH]c(C)cc4c3F)c2c1C Show InChI InChI=1S/C18H18FN5O3/c1-9-4-12-15(19)13(5-20-17(12)23-9)27-18-16-11(3)14(26-7-10(2)25)6-24(16)22-8-21-18/h4-6,8,10,25H,7H2,1-3H3,(H,20,23)/t10-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human VEGFR2				Bioorg Med Chem Lett 18: 2985-9 (2008) Article DOI: 10.1016/j.bmcl.2008.03.057 BindingDB Entry DOI: 10.7270/Q28053HZ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374696 (CHEMBL404401) Show SMILES CNc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C22H22F2N8O2/c1-10(2)17-13(21-30-31-22(25-3)34-21)8-32-18(17)19(26-9-27-32)29-16-6-12(14(23)7-15(16)24)20(33)28-11-4-5-11/h6-11H,4-5H2,1-3H3,(H,25,31)(H,28,33)(H,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374712 (CHEMBL270869) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(NCC(C)(C)CN)o1 Show InChI InChI=1S/C26H31F2N9O2/c1-13(2)20-16(24-35-36-25(39-24)30-11-26(3,4)10-29)9-37-21(20)22(31-12-32-37)34-19-7-15(17(27)8-18(19)28)23(38)33-14-5-6-14/h7-9,12-14H,5-6,10-11,29H2,1-4H3,(H,30,36)(H,33,38)(H,31,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317755 (2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...) Show SMILES Fc1cc(Nc2ncccc2C(=O)Nc2ccccc2)ccc1Oc1ccnc2[nH]ccc12 Show InChI InChI=1S/C25H18FN5O2/c26-20-15-17(8-9-22(20)33-21-11-14-29-23-18(21)10-13-28-23)30-24-19(7-4-12-27-24)25(32)31-16-5-2-1-3-6-16/h1-15H,(H,27,30)(H,28,29)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374714 (CHEMBL407708) Show SMILES CC(C)Nc1nnc(o1)-c1cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c2c1C(C)C Show InChI InChI=1S/C24H26F2N8O2/c1-11(2)19-15(23-32-33-24(36-23)29-12(3)4)9-34-20(19)21(27-10-28-34)31-18-7-14(16(25)8-17(18)26)22(35)30-13-5-6-13/h7-13H,5-6H2,1-4H3,(H,29,33)(H,30,35)(H,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50374716 (CHEMBL429845) Show SMILES CC(C)c1c(cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12)-c1nnc(o1)N1CCN(C)CC1 Show InChI InChI=1S/C26H29F2N9O2/c1-14(2)21-17(25-33-34-26(39-25)36-8-6-35(3)7-9-36)12-37-22(21)23(29-13-30-37)32-20-10-16(18(27)11-19(20)28)24(38)31-15-4-5-15/h10-15H,4-9H2,1-3H3,(H,31,38)(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 1354-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.012 BindingDB Entry DOI: 10.7270/Q2XK8GD2
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317764 (4-(4-(2-aminopyridin-4-yloxy)-3-fluorophenylamino)...) Show SMILES Nc1cc(Oc2ccc(Nc3ncncc3C(=O)Nc3ccc(F)cc3F)cc2F)ccn1 Show InChI InChI=1S/C22H15F3N6O2/c23-12-1-3-18(16(24)7-12)31-22(32)15-10-27-11-29-21(15)30-13-2-4-19(17(25)8-13)33-14-5-6-28-20(26)9-14/h1-11H,(H2,26,28)(H,31,32)(H,27,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50317752 (2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluoroph...) Show SMILES Fc1cc(Nc2ncccc2C(=O)Nc2ccccc2Cl)ccc1Oc1ccnc2[nH]ccc12 Show InChI InChI=1S/C25H17ClFN5O2/c26-18-5-1-2-6-20(18)32-25(33)17-4-3-11-28-24(17)31-15-7-8-22(19(27)14-15)34-21-10-13-30-23-16(21)9-12-29-23/h1-14H,(H,28,31)(H,29,30)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant c-met N terminal domain expressed in Hi5 insect cells after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 20: 2998-3002 (2010) Article DOI: 10.1016/j.bmcl.2010.01.042 BindingDB Entry DOI: 10.7270/Q2PN95TM
					More data for this Ligand-Target Pair

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