Compile Data Set for Download or QSAR

Found 546 hits with Last Name = 'kim' and Initial = 'yt'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502377 (N-[4-(7- methoxy-1- methyl- [1,2,4]tri- azolo[4,3-...) Show SMILES COc1ccc2c(c1)nc(NCCCCNC(=O)C(C)C)c1nnc(C)n21 Show InChI InChI=1S/C19H26N6O2/c1-12(2)19(26)21-10-6-5-9-20-17-18-24-23-13(3)25(18)16-8-7-14(27-4)11-15(16)22-17/h7-8,11-12H,5-6,9-10H2,1-4H3,(H,20,22)(H,21,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502344 (2-methoxy-N- {4-[1-methyl- 7-(1-methyl- 1H-benzo- ...) Show SMILES COc1ccccc1C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C Show InChI InChI=1S/C30H30N8O2/c1-19-35-36-29-27(31-16-8-9-17-32-30(39)21-10-4-7-13-26(21)40-3)33-23-18-20(14-15-25(23)38(19)29)28-34-22-11-5-6-12-24(22)37(28)2/h4-7,10-15,18H,8-9,16-17H2,1-3H3,(H,31,33)(H,32,39)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502348 (3-methyl-N- {4-[1-methyl- 7-(1-propyl- 1H- benzoim...) Show SMILES CCCn1c(nc2ccccc12)-c1ccc2c(c1)nc(NCCCCNC(=O)CC(C)C)c1nnc(C)n21 Show InChI InChI=1S/C29H36N8O/c1-5-16-36-24-11-7-6-10-22(24)33-28(36)21-12-13-25-23(18-21)32-27(29-35-34-20(4)37(25)29)31-15-9-8-14-30-26(38)17-19(2)3/h6-7,10-13,18-19H,5,8-9,14-17H2,1-4H3,(H,30,38)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502479 ((S)-(1-{4-[7- (2-methoxy- ethoxy)-1- methyl- [1,2,...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](NC(=O)OCC(C)C)C(C)C)c1nnc(C)n21 |r| Show InChI InChI=1S/C27H41N7O5/c1-17(2)16-39-27(36)31-23(18(3)4)26(35)29-12-8-7-11-28-24-25-33-32-19(5)34(25)22-10-9-20(15-21(22)30-24)38-14-13-37-6/h9-10,15,17-18,23H,7-8,11-14,16H2,1-6H3,(H,28,30)(H,29,35)(H,31,36)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502480 ((S)-(1-{4-[7- (2-methoxy- ethoxy)-1- methyl- [1,2,...) Show SMILES CCCOC(=O)N[C@@H](C(C)C)C(=O)NCCCCNc1nc2cc(OCCOC)ccc2n2c(C)nnc12 |r| Show InChI InChI=1S/C26H39N7O5/c1-6-13-38-26(35)30-22(17(2)3)25(34)28-12-8-7-11-27-23-24-32-31-18(4)33(24)21-10-9-19(16-20(21)29-23)37-15-14-36-5/h9-10,16-17,22H,6-8,11-15H2,1-5H3,(H,27,29)(H,28,34)(H,30,35)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502481 ((S)-(1-{4-[7- (2-methoxy- ethoxy)-1- methyl- [1,2,...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)c1nnc(C)n21 |r| Show InChI InChI=1S/C26H39N7O5/c1-16(2)22(30-26(35)38-17(3)4)25(34)28-12-8-7-11-27-23-24-32-31-18(5)33(24)21-10-9-19(15-20(21)29-23)37-14-13-36-6/h9-10,15-17,22H,7-8,11-14H2,1-6H3,(H,27,29)(H,28,34)(H,30,35)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502494 (2,3- dichloro-N- {4-[7-(2- methoxy- ethoxy)-1- met...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)c1cccc(Cl)c1Cl)c1nnc(C)n21 Show InChI InChI=1S/C24H26Cl2N6O3/c1-15-30-31-23-22(29-19-14-16(35-13-12-34-2)8-9-20(19)32(15)23)27-10-3-4-11-28-24(33)17-6-5-7-18(25)21(17)26/h5-9,14H,3-4,10-13H2,1-2H3,(H,27,29)(H,28,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502328 (US11028090, Example 222) Show SMILES CC(C)CC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C Show InChI InChI=1S/C27H32N8O/c1-17(2)15-24(36)28-13-7-8-14-29-25-27-33-32-18(3)35(27)23-12-11-19(16-21(23)30-25)26-31-20-9-5-6-10-22(20)34(26)4/h5-6,9-12,16-17H,7-8,13-15H2,1-4H3,(H,28,36)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502334 (N-{4-[7-(5,6- dimethoxy- 1H-benzo- imidazole-2- yl...) Show SMILES CNc1cc2nc([nH]c2cc1OC)-c1ccc2c(c1)nc(NCCCCNC(=O)CC(C)C)c1nnc(C)n21 Show InChI InChI=1S/C28H35N9O2/c1-16(2)12-25(38)30-10-6-7-11-31-27-28-36-35-17(3)37(28)23-9-8-18(13-21(23)34-27)26-32-19-14-22(29-4)24(39-5)15-20(19)33-26/h8-9,13-16,29H,6-7,10-12H2,1-5H3,(H,30,38)(H,31,34)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254040 (US9493430, 593) Show SMILES COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1c(F)cc(cc1F)C(O)=O |r,c:9| Show InChI InChI=1S/C35H31F8NO5/c1-17-30(19-9-22(34(38,39)40)14-23(10-19)35(41,42)43)49-32(47)44(17)16-21-15-33(2,3)8-7-24(21)25-11-18(5-6-28(25)48-4)29-26(36)12-20(31(45)46)13-27(29)37/h5-6,9-14,17,30H,7-8,15-16H2,1-4H3,(H,45,46)/t17-,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254048 (US9493430, 618) Show SMILES COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1C(F)(F)F)C(O)=O |r,c:9| Show InChI InChI=1S/C36H32F9NO5/c1-18-30(21-11-23(34(37,38)39)15-24(12-21)35(40,41)42)51-32(49)46(18)17-22-16-33(2,3)10-9-25(22)27-13-19(6-8-29(27)50-4)26-7-5-20(31(47)48)14-28(26)36(43,44)45/h5-8,11-15,18,30H,9-10,16-17H2,1-4H3,(H,47,48)/t18-,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254050 (US9493430, 631) Show SMILES COc1cc(F)c(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1Cl)C(O)=O |r,c:10| Show InChI InChI=1S/C35H31ClF7NO5/c1-17-30(19-9-21(34(38,39)40)12-22(10-19)35(41,42)43)49-32(47)44(17)16-20-15-33(2,3)8-7-23(20)26-13-25(28(37)14-29(26)48-4)24-6-5-18(31(45)46)11-27(24)36/h5-6,9-14,17,30H,7-8,15-16H2,1-4H3,(H,45,46)/t17-,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254058 (US9493430, 684) Show SMILES COc1cc(C)c(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1C)C(O)=O |r,c:10| Show InChI InChI=1S/C37H37F6NO5/c1-19-11-22(33(45)46)7-8-27(19)29-16-30(31(48-6)12-20(29)2)28-9-10-35(4,5)17-24(28)18-44-21(3)32(49-34(44)47)23-13-25(36(38,39)40)15-26(14-23)37(41,42)43/h7-8,11-16,21,32H,9-10,17-18H2,1-6H3,(H,45,46)/t21-,32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502501 (N-{4-[7-(2- methoxy- ethoxy)-1- methyl- [1,2,4]tri...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)Cc1ccccc1)c1nnc(C)n21 Show InChI InChI=1S/C25H30N6O3/c1-18-29-30-25-24(27-13-7-6-12-26-23(32)16-19-8-4-3-5-9-19)28-21-17-20(34-15-14-33-2)10-11-22(21)31(18)25/h3-5,8-11,17H,6-7,12-16H2,1-2H3,(H,26,32)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502455 (US11028090, Example 372 | {4-[7-(2- methoxy- ethox...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)Oc1ccccc1)c1nnc(C)n21 Show InChI InChI=1S/C24H28N6O4/c1-17-28-29-23-22(25-12-6-7-13-26-24(31)34-18-8-4-3-5-9-18)27-20-16-19(33-15-14-32-2)10-11-21(20)30(17)23/h3-5,8-11,16H,6-7,12-15H2,1-2H3,(H,25,27)(H,26,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502471 (2-(S)- hydroxy-N- {4-[7-(2- methoxy- ethoxy)-1- me...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](O)C(C)C)c1nnc(C)n21 |r| Show InChI InChI=1S/C22H32N6O4/c1-14(2)19(29)22(30)24-10-6-5-9-23-20-21-27-26-15(3)28(21)18-8-7-16(13-17(18)25-20)32-12-11-31-4/h7-8,13-14,19,29H,5-6,9-12H2,1-4H3,(H,23,25)(H,24,30)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502217 (N-[4-(7,8- dimethoxy-1- methyl-[1,2,4] triazolo[4,...) Show SMILES COc1cc2nc(NCCCCNC(=O)[C@@H](O)C(C)C)c3nnc(C)n3c2cc1OC |r| Show InChI InChI=1S/C21H30N6O4/c1-12(2)18(28)21(29)23-9-7-6-8-22-19-20-26-25-13(3)27(20)15-11-17(31-5)16(30-4)10-14(15)24-19/h10-12,18,28H,6-9H2,1-5H3,(H,22,24)(H,23,29)/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502290 (US11028090, Example 176 | [4-(7,8- diethoxy-1- met...) Show SMILES CCOc1cc2nc(NCCCCNC(=O)OCC(C)C)c3nnc(C)n3c2cc1OCC Show InChI InChI=1S/C23H34N6O4/c1-6-31-19-12-17-18(13-20(19)32-7-2)29-16(5)27-28-22(29)21(26-17)24-10-8-9-11-25-23(30)33-14-15(3)4/h12-13,15H,6-11,14H2,1-5H3,(H,24,26)(H,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502340 (2,2-difluoro- N-{4-[1- methyl-7-(1- methyl-1H- ben...) Show SMILES CCC(F)(F)C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C Show InChI InChI=1S/C26H28F2N8O/c1-4-26(27,28)25(37)30-14-8-7-13-29-22-24-34-33-16(2)36(24)21-12-11-17(15-19(21)31-22)23-32-18-9-5-6-10-20(18)35(23)3/h5-6,9-12,15H,4,7-8,13-14H2,1-3H3,(H,29,31)(H,30,37)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502343 (4-methyl- pentanoic acid-{4-[1- methyl-7- (1-meth...) Show SMILES CC(C)CCC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2n1C Show InChI InChI=1S/C28H34N8O/c1-18(2)11-14-25(37)29-15-7-8-16-30-26-28-34-33-19(3)36(28)24-13-12-20(17-22(24)31-26)27-32-21-9-5-6-10-23(21)35(27)4/h5-6,9-10,12-13,17-18H,7-8,11,14-16H2,1-4H3,(H,29,37)(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254054 (US9493430, 661) Show SMILES COc1cc(F)c(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1F)C(O)=O |r,c:10| Show InChI InChI=1S/C35H31F8NO5/c1-17-30(19-9-21(34(38,39)40)12-22(10-19)35(41,42)43)49-32(47)44(17)16-20-15-33(2,3)8-7-23(20)26-13-25(28(37)14-29(26)48-4)24-6-5-18(31(45)46)11-27(24)36/h5-6,9-14,17,30H,7-8,15-16H2,1-4H3,(H,45,46)/t17-,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502502 (1-isopropyl-3- {4-[7-(2- methoxy- ethoxy)-1- methy...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)NC(C)C)c1nnc(C)n21 Show InChI InChI=1S/C21H31N7O3/c1-14(2)24-21(29)23-10-6-5-9-22-19-20-27-26-15(3)28(20)18-8-7-16(13-17(18)25-19)31-12-11-30-4/h7-8,13-14H,5-6,9-12H2,1-4H3,(H,22,25)(H2,23,24,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502466 (4-methyl- pentanoic acid{4-[7- (2-methoxy- ethoxy)...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)CCC(C)C)c1nnc(C)n21 Show InChI InChI=1S/C23H34N6O3/c1-16(2)7-10-21(30)24-11-5-6-12-25-22-23-28-27-17(3)29(23)20-9-8-18(15-19(20)26-22)32-14-13-31-4/h8-9,15-16H,5-7,10-14H2,1-4H3,(H,24,30)(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502475 (3-cyclopentyl- N-{4-[7-(2- methoxy- ethoxy)-1- met...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)CCC1CCCC1)c1nnc(C)n21 Show InChI InChI=1S/C25H36N6O3/c1-18-29-30-25-24(27-14-6-5-13-26-23(32)12-9-19-7-3-4-8-19)28-21-17-20(34-16-15-33-2)10-11-22(21)31(18)25/h10-11,17,19H,3-9,12-16H2,1-2H3,(H,26,32)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502336 (US11028090, Example 229 | {4-[1-methyl- 7-(1-methy...) Show SMILES Cc1nnc2c(NCCCCNC(=O)OC3CCCC3)nc3cc(ccc3n12)-c1nc2ccccc2n1C Show InChI InChI=1S/C28H32N8O2/c1-18-33-34-27-25(29-15-7-8-16-30-28(37)38-20-9-3-4-10-20)31-22-17-19(13-14-24(22)36(18)27)26-32-21-11-5-6-12-23(21)35(26)2/h5-6,11-14,17,20H,3-4,7-10,15-16H2,1-2H3,(H,29,31)(H,30,37)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254034 (US9493430, 574) Show SMILES COc1cc(F)c(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1C)C(O)=O |r,c:10| Show InChI InChI=1S/C36H34F7NO5/c1-18-10-20(32(45)46)6-7-25(18)27-14-28(30(48-5)15-29(27)37)26-8-9-34(3,4)16-22(26)17-44-19(2)31(49-33(44)47)21-11-23(35(38,39)40)13-24(12-21)36(41,42)43/h6-7,10-15,19,31H,8-9,16-17H2,1-5H3,(H,45,46)/t19-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502449 (US11028090, Example 366 | US11028090, Example 428 ...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)OC(C)C)c1nnc(C)n21 Show InChI InChI=1S/C21H30N6O4/c1-14(2)31-21(28)23-10-6-5-9-22-19-20-26-25-15(3)27(20)18-8-7-16(13-17(18)24-19)30-12-11-29-4/h7-8,13-14H,5-6,9-12H2,1-4H3,(H,22,24)(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502392 (2-(R)- hydroxy-N- [4-(7- methoxy-1- methyl- [1,2,4...) Show SMILES COc1ccc2c(c1)nc(NCCCCNC(=O)[C@H](O)C(C)C)c1nnc(C)n21 |r| Show InChI InChI=1S/C20H28N6O3/c1-12(2)17(27)20(28)22-10-6-5-9-21-18-19-25-24-13(3)26(19)16-8-7-14(29-4)11-15(16)23-18/h7-8,11-12,17,27H,5-6,9-10H2,1-4H3,(H,21,23)(H,22,28)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502412 ((S)-{1-[4- (7-methoxy- 1-methyl- [1,2,4]tri- azolo...) Show SMILES COc1ccc2c(c1)nc(NCCCCNC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)c1nnc(C)n21 |r| Show InChI InChI=1S/C24H35N7O4/c1-14(2)20(28-24(33)35-15(3)4)23(32)26-12-8-7-11-25-21-22-30-29-16(5)31(22)19-10-9-17(34-6)13-18(19)27-21/h9-10,13-15,20H,7-8,11-12H2,1-6H3,(H,25,27)(H,26,32)(H,28,33)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502331 (N-{4-[7-(1H- benzo- imidazole-2- yl)-1-methyl- [1,...) Show SMILES CC(C)[C@@H](O)C(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1nc2ccccc2[nH]1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502276 (US11028090, Example 161 | [4-(8- methoxy-1,6- dime...) Show SMILES COc1cc(C)c2nc(NCCCCNC(=O)OC(C)C)c3nnc(C)n3c2c1 Show InChI InChI=1S/C20H28N6O3/c1-12(2)29-20(27)22-9-7-6-8-21-18-19-25-24-14(4)26(19)16-11-15(28-5)10-13(3)17(16)23-18/h10-12H,6-9H2,1-5H3,(H,21,23)(H,22,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502288 (US11028090, Example 173 | [4-(7,8- diethoxy-1- met...) Show SMILES CCOc1cc2nc(NCCCCNC(=O)OC(C)(C)C)c3nnc(C)n3c2cc1OCC Show InChI InChI=1S/C23H34N6O4/c1-7-31-18-13-16-17(14-19(18)32-8-2)29-15(3)27-28-21(29)20(26-16)24-11-9-10-12-25-22(30)33-23(4,5)6/h13-14H,7-12H2,1-6H3,(H,24,26)(H,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502252 (2-(S)-hydroxy-N- [4-(8-methoxy- 1-methyl-[1,2,4] t...) Show SMILES COc1ccc2nc(NCCCCNC(=O)[C@@H](O)C(C)C)c3nnc(C)n3c2c1 |r| Show InChI InChI=1S/C20H28N6O3/c1-12(2)17(27)20(28)22-10-6-5-9-21-18-19-25-24-13(3)26(19)16-11-14(29-4)7-8-15(16)23-18/h7-8,11-12,17,27H,5-6,9-10H2,1-4H3,(H,21,23)(H,22,28)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502637 (US11028090, Example 579) Show SMILES Cc1noc(C)c1-c1ccc2nc(NCCCCN)c3nnc(C)n3c2c1 Show InChI InChI=1S/C19H23N7O/c1-11-17(12(2)27-25-11)14-6-7-15-16(10-14)26-13(3)23-24-19(26)18(22-15)21-9-5-4-8-20/h6-7,10H,4-5,8-9,20H2,1-3H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502157 (2-(S)- hydroxy-N- [4-(1- methyl- [1,2,4] triazolo ...) Show SMILES CC(C)[C@H](O)C(=O)NCCCCNc1nc2ccccc2n2c(C)nnc12 |r| Show InChI InChI=1S/C19H26N6O2/c1-12(2)16(26)19(27)21-11-7-6-10-20-17-18-24-23-13(3)25(18)15-9-5-4-8-14(15)22-17/h4-5,8-9,12,16,26H,6-7,10-11H2,1-3H3,(H,20,22)(H,21,27)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502641 (N-{4-[7- (3,5- dimethyl- isoxazol-4- yl)-1- methyl...) Show SMILES CC(C)CC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-c1c(C)noc1C Show InChI InChI=1S/C24H31N7O2/c1-14(2)12-21(32)25-10-6-7-11-26-23-24-29-28-17(5)31(24)20-9-8-18(13-19(20)27-23)22-15(3)30-33-16(22)4/h8-9,13-14H,6-7,10-12H2,1-5H3,(H,25,32)(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502527 (US11028090, Example 448) Show SMILES CC(C)Oc1ccc2c(c1)nc(NCCCCN)c1nnc(C)n21 Show InChI InChI=1S/C17H24N6O/c1-11(2)24-13-6-7-15-14(10-13)20-16(19-9-5-4-8-18)17-22-21-12(3)23(15)17/h6-7,10-11H,4-5,8-9,18H2,1-3H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502557 (2-(S)- hydroxy-N- [4-(7- methoxy-1- methyl-8- trif...) Show SMILES COc1cc2nc(NCCCCNC(=O)[C@@H](O)C(C)C)c3nnc(C)n3c2cc1C(F)(F)F |r| Show InChI InChI=1S/C21H27F3N6O3/c1-11(2)17(31)20(32)26-8-6-5-7-25-18-19-29-28-12(3)30(19)15-9-13(21(22,23)24)16(33-4)10-14(15)27-18/h9-11,17,31H,5-8H2,1-4H3,(H,25,27)(H,26,32)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502566 (4-(7- imidazole- 1-yl-1- methyl- [1,2,4]triazolo[4...) Show SMILES CC(C)COC(=O)NCCCCNc1nc2cc(ccc2n2c(C)nnc12)-n1ccnc1 Show InChI InChI=1S/C22H28N8O2/c1-15(2)13-32-22(31)25-9-5-4-8-24-20-21-28-27-16(3)30(21)19-7-6-17(12-18(19)26-20)29-11-10-23-14-29/h6-7,10-12,14-15H,4-5,8-9,13H2,1-3H3,(H,24,26)(H,25,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502450 (US11028090, Example 367 | US11028090, Example 368 ...) Show SMILES CCCOC(=O)NCCCCNc1nc2cc(OCCOC)ccc2n2c(C)nnc12 Show InChI InChI=1S/C21H30N6O4/c1-4-11-31-21(28)23-10-6-5-9-22-19-20-26-25-15(2)27(20)18-8-7-16(14-17(18)24-19)30-13-12-29-3/h7-8,14H,4-6,9-13H2,1-3H3,(H,22,24)(H,23,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502465 (N-{4-[7-(2- methoxy- ethoxy)-1- methyl- [1,2,4]tri...) Show SMILES COCCOc1ccc2c(c1)nc(NCCCCNC(=O)CC(C)(C)C)c1nnc(C)n21 Show InChI InChI=1S/C23H34N6O3/c1-16-27-28-22-21(25-11-7-6-10-24-20(30)15-23(2,3)4)26-18-14-17(32-13-12-31-5)8-9-19(18)29(16)22/h8-9,14H,6-7,10-13,15H2,1-5H3,(H,24,30)(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502473 (2,2- difluoro-N- {4-[7-(2- methoxy- ethoxy)-1- met...) Show SMILES CCC(F)(F)C(=O)NCCCCNc1nc2cc(OCCOC)ccc2n2c(C)nnc12 Show InChI InChI=1S/C21H28F2N6O3/c1-4-21(22,23)20(30)25-10-6-5-9-24-18-19-28-27-14(2)29(19)17-8-7-15(13-16(17)26-18)32-12-11-31-3/h7-8,13H,4-6,9-12H2,1-3H3,(H,24,26)(H,25,30)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502213 (4-methyl- pentanoic acid [4-(7,8- dimethoxy-1- met...) Show SMILES COc1cc2nc(NCCCCNC(=O)CCC(C)C)c3nnc(C)n3c2cc1OC Show InChI InChI=1S/C22H32N6O3/c1-14(2)8-9-20(29)23-10-6-7-11-24-21-22-27-26-15(3)28(22)17-13-19(31-5)18(30-4)12-16(17)25-21/h12-14H,6-11H2,1-5H3,(H,23,29)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502640 (US11028090, Example 583) Show SMILES Cc1noc(C)c1-c1ccc2c(c1)nc(NCCCCNC(=O)OC(C)(C)C)c1nnc(C)n21 Show InChI InChI=1S/C24H31N7O3/c1-14-20(15(2)34-30-14)17-9-10-19-18(13-17)27-21(22-29-28-16(3)31(19)22)25-11-7-8-12-26-23(32)33-24(4,5)6/h9-10,13H,7-8,11-12H2,1-6H3,(H,25,27)(H,26,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM502656 (US11028090, Example 622 | US11028090, Example 623 ...) Show SMILES CCc1nnc2c(NCCCCNC(=O)OC(C)C)nc3cc(OC)ccc3n12 Show InChI InChI=1S/C20H28N6O3/c1-5-17-24-25-19-18(21-10-6-7-11-22-20(27)29-13(2)3)23-15-12-14(28-4)8-9-16(15)26(17)19/h8-9,12-13H,5-7,10-11H2,1-4H3,(H,21,23)(H,22,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Dong Wha Pharm. Co., Ltd.; Korea Research Institute of Chemical Technology US Patent					Assay Description The following experiment was performed to evaluate the ability of [1,2,4]triazolo[4,3-a]quinoxaline derivative of the present invention to inhibit th...				US Patent US11028090 (2021) BindingDB Entry DOI: 10.7270/Q22J6G0T
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254055 (US9493430, 668) Show SMILES C[C@H]1[C@H](OC(=O)N1CC1=C(CCC(C)(C)C1)c1cc(F)cc(c1)-c1ccc(cc1C(F)(F)F)C(O)=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F |r,t:9| Show InChI InChI=1S/C35H29F10NO4/c1-17-29(21-9-23(33(37,38)39)14-24(10-21)34(40,41)42)50-31(49)46(17)16-22-15-32(2,3)7-6-26(22)19-8-20(12-25(36)11-19)27-5-4-18(30(47)48)13-28(27)35(43,44)45/h4-5,8-14,17,29H,6-7,15-16H2,1-3H3,(H,47,48)/t17-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254037 (US9493430, 584) Show SMILES COc1ncc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1Cl)C(O)=O |r,c:9| Show InChI InChI=1S/C34H31ClF6N2O5/c1-17-28(19-9-22(33(36,37)38)13-23(10-19)34(39,40)41)48-31(46)43(17)16-21-14-32(2,3)8-7-24(21)26-11-20(15-42-29(26)47-4)25-6-5-18(30(44)45)12-27(25)35/h5-6,9-13,15,17,28H,7-8,14,16H2,1-4H3,(H,44,45)/t17-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254030 (US9493430, 557) Show SMILES COc1ncc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1C)C(O)=O |r,c:9| Show InChI InChI=1S/C35H34F6N2O5/c1-18-10-20(31(44)45)6-7-26(18)22-13-28(30(47-5)42-16-22)27-8-9-33(3,4)15-23(27)17-43-19(2)29(48-32(43)46)21-11-24(34(36,37)38)14-25(12-21)35(39,40)41/h6-7,10-14,16,19,29H,8-9,15,17H2,1-5H3,(H,44,45)/t19-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254028 (US9493430, 554) Show SMILES COc1ccc(cc1C1=C(CN2[C@@H](C)[C@H](OC2=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC(C)(C)CC1)-c1ccc(cc1C)C(O)=O |r,c:9| Show InChI InChI=1S/C36H35F6NO5/c1-19-12-22(32(44)45)6-8-27(19)21-7-9-30(47-5)29(15-21)28-10-11-34(3,4)17-24(28)18-43-20(2)31(48-33(43)46)23-13-25(35(37,38)39)16-26(14-23)36(40,41)42/h6-9,12-16,20,31H,10-11,17-18H2,1-5H3,(H,44,45)/t20-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM254066 (US9493430, 756) Show SMILES CCNC(=O)c1ccc(-c2ccc(F)c(c2)C2=C(CN3[C@@H](C)[C@H](OC3=O)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)CC(C)(C)CC2)c(c1)C(F)(F)F |r,c:17| Show InChI InChI=1S/C37H34F10N2O3/c1-5-48-32(50)21-6-8-27(29(15-21)37(45,46)47)20-7-9-30(38)28(14-20)26-10-11-34(3,4)17-23(26)18-49-19(2)31(52-33(49)51)22-12-24(35(39,40)41)16-25(13-22)36(42,43)44/h6-9,12-16,19,31H,5,10-11,17-18H2,1-4H3,(H,48,50)/t19-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Chong Kun Dang Pharmaceutical Corp. US Patent					Assay Description As a protein source for cholesteryl ester transfer, plasma from healthy persons was used, and as a cholesteryl ester receptor, LDL from healthy perso...				US Patent US9493430 (2016) BindingDB Entry DOI: 10.7270/Q2W37V7V
					More data for this Ligand-Target Pair

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