Compile Data Set for Download or QSAR

Found 63 hits with Last Name = 'kothmirkar' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345760 (1-(Benzenesulfonyl)-5-(piperazin-1-yl-methyl)-1H-i...) Show SMILES O=S(=O)(c1ccccc1)n1ccc2cc(CN3CCNCC3)ccc12 Show InChI InChI=1S/C19H21N3O2S/c23-25(24,18-4-2-1-3-5-18)22-11-8-17-14-16(6-7-19(17)22)15-21-12-9-20-10-13-21/h1-8,11,14,20H,9-10,12-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345777 (1-(2-Bromo benzenesulfonyl)-5-(4-ethylpiperazin-1-...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccccc2Br)CC1 Show InChI InChI=1S/C21H24BrN3O2S/c1-2-23-11-13-24(14-12-23)16-17-7-8-20-18(15-17)9-10-25(20)28(26,27)21-6-4-3-5-19(21)22/h3-10,15H,2,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345758 (3-chloro-1-(4-fluoro benzenesulfonyl)-5-(piperazin...) Show SMILES Fc1ccc(cc1)S(=O)(=O)n1cc(Cl)c2cc(CN3CCNCC3)ccc12 Show InChI InChI=1S/C19H19ClFN3O2S/c20-18-13-24(27(25,26)16-4-2-15(21)3-5-16)19-6-1-14(11-17(18)19)12-23-9-7-22-8-10-23/h1-6,11,13,22H,7-10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345754 (3-chloro-1-(4-fluoro benzenesulfonyl)-5-(4-methylp...) Show SMILES CN1CCN(Cc2ccc3n(cc(Cl)c3c2)S(=O)(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C20H21ClFN3O2S/c1-23-8-10-24(11-9-23)13-15-2-7-20-18(12-15)19(21)14-25(20)28(26,27)17-5-3-16(22)4-6-17/h2-7,12,14H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345763 (1-(4-Chloro benzenesulfonyl)-5-(4-methylpiperazin-...) Show SMILES CN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C20H22ClN3O2S/c1-22-10-12-23(13-11-22)15-16-2-7-20-17(14-16)8-9-24(20)27(25,26)19-5-3-18(21)4-6-19/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345762 (1-(3-trifluoromethyl benzenesulfonyl)-5-(4-methylp...) Show SMILES CN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C21H22F3N3O2S/c1-25-9-11-26(12-10-25)15-16-5-6-20-17(13-16)7-8-27(20)30(28,29)19-4-2-3-18(14-19)21(22,23)24/h2-8,13-14H,9-12,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345772 (1-(4-Fluoro benzenesulfonyl)-5-(4-ethylpiperazin-1...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C21H24FN3O2S/c1-2-23-11-13-24(14-12-23)16-17-3-8-21-18(15-17)9-10-25(21)28(26,27)20-6-4-19(22)5-7-20/h3-10,15H,2,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345753 (3-Chloro-1-(2,4-difluorobenzenesulfonyl)-5-(4-meth...) Show SMILES CN1CCN(Cc2ccc3n(cc(Cl)c3c2)S(=O)(=O)c2ccc(F)cc2F)CC1 Show InChI InChI=1S/C20H20ClF2N3O2S/c1-24-6-8-25(9-7-24)12-14-2-4-19-16(10-14)17(21)13-26(19)29(27,28)20-5-3-15(22)11-18(20)23/h2-5,10-11,13H,6-9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345769 (1-Benzenesulfonyl-5-(4-methylpiperazin-1-yl-methyl...) Show SMILES CN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccccc2)CC1 Show InChI InChI=1S/C20H23N3O2S/c1-21-11-13-22(14-12-21)16-17-7-8-20-18(15-17)9-10-23(20)26(24,25)19-5-3-2-4-6-19/h2-10,15H,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345756 (1-(2-Chloro-5-trifluoromethyl benzenesulfonyl)-3-c...) Show SMILES CN1CCN(Cc2ccc3n(cc(Cl)c3c2)S(=O)(=O)c2cc(ccc2Cl)C(F)(F)F)CC1 Show InChI InChI=1S/C21H20Cl2F3N3O2S/c1-27-6-8-28(9-7-27)12-14-2-5-19-16(10-14)18(23)13-29(19)32(30,31)20-11-15(21(24,25)26)3-4-17(20)22/h2-5,10-11,13H,6-9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345776 (1-(2,3-Dichlorobenzenesulfonyl)-5-(4-ethylpiperazi...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2cccc(Cl)c2Cl)CC1 Show InChI InChI=1S/C21H23Cl2N3O2S/c1-2-24-10-12-25(13-11-24)15-16-6-7-19-17(14-16)8-9-26(19)29(27,28)20-5-3-4-18(22)21(20)23/h3-9,14H,2,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345757 (3-Chloro-1-(2,4-difluoro benzenesulfonyl)-5-(piper...) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)n1cc(Cl)c2cc(CN3CCNCC3)ccc12 Show InChI InChI=1S/C19H18ClF2N3O2S/c20-16-12-25(28(26,27)19-4-2-14(21)10-17(19)22)18-3-1-13(9-15(16)18)11-24-7-5-23-6-8-24/h1-4,9-10,12,23H,5-8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345775 (1-(3-trifluoromethyl benzenesulfonyl)-5-(4-ethylpi...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C22H24F3N3O2S/c1-2-26-10-12-27(13-11-26)16-17-6-7-21-18(14-17)8-9-28(21)31(29,30)20-5-3-4-19(15-20)22(23,24)25/h3-9,14-15H,2,10-13,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345774 (1-(4-Isopropyl benzenesulfonyl)-5-(4-ethylpiperazi...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccc(cc2)C(C)C)CC1 Show InChI InChI=1S/C24H31N3O2S/c1-4-25-13-15-26(16-14-25)18-20-5-10-24-22(17-20)11-12-27(24)30(28,29)23-8-6-21(7-9-23)19(2)3/h5-12,17,19H,4,13-16,18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345761 (1-(2-Bromo benzenesulfonyl)-5-(piperazin-1-yl-meth...) Show SMILES Brc1ccccc1S(=O)(=O)n1ccc2cc(CN3CCNCC3)ccc12 Show InChI InChI=1S/C19H20BrN3O2S/c20-17-3-1-2-4-19(17)26(24,25)23-10-7-16-13-15(5-6-18(16)23)14-22-11-8-21-9-12-22/h1-7,10,13,21H,8-9,11-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345765 (1-(2-Bromo benzenesulfonyl)-5-(4-methylpiperazin-1...) Show SMILES CN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccccc2Br)CC1 Show InChI InChI=1S/C20H22BrN3O2S/c1-22-10-12-23(13-11-22)15-16-6-7-19-17(14-16)8-9-24(19)27(25,26)20-5-3-2-4-18(20)21/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345755 (1-(4-Chlorobenzenesulfonyl)-3-chloro-5-(4-methyl p...) Show SMILES CN1CCN(Cc2ccc3n(cc(Cl)c3c2)S(=O)(=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C20H21Cl2N3O2S/c1-23-8-10-24(11-9-23)13-15-2-7-20-18(12-15)19(22)14-25(20)28(26,27)17-5-3-16(21)4-6-17/h2-7,12,14H,8-11,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345773 (1-(4-Methyl benzenesulfonyl)-5-(4-ethylpiperazin-1...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C22H27N3O2S/c1-3-23-12-14-24(15-13-23)17-19-6-9-22-20(16-19)10-11-25(22)28(26,27)21-7-4-18(2)5-8-21/h4-11,16H,3,12-15,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236526 (2-Ethoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]b...) Show SMILES CCOc1ccc2C3C(=C(CC(C)N(C)C)c2c1)c1ccccc1S3(=O)=O |t:8| Show InChI InChI=1S/C22H25NO3S/c1-5-26-15-10-11-16-18(13-15)19(12-14(2)23(3)4)21-17-8-6-7-9-20(17)27(24,25)22(16)21/h6-11,13-14,22H,5,12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11.1	-47.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345766 (1-(2-Chloro-5-trifluoromethyl benzenesulfonyl)-5-(...) Show SMILES CN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2cc(ccc2Cl)C(F)(F)F)CC1 Show InChI InChI=1S/C21H21ClF3N3O2S/c1-26-8-10-27(11-9-26)14-15-2-5-19-16(12-15)6-7-28(19)31(29,30)20-13-17(21(23,24)25)3-4-18(20)22/h2-7,12-13H,8-11,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236524 ( 2-Methoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl...) Show SMILES COc1ccc2C3C(=C(CC(C)N(C)C)c2c1)c1ccccc1S3(=O)=O |t:7| Show InChI InChI=1S/C21H23NO3S/c1-13(22(2)3)11-18-17-12-14(25-4)9-10-15(17)21-20(18)16-7-5-6-8-19(16)26(21,23)24/h5-10,12-13,21H,11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11.6	-47.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345771 (1-(2,4-Difluoro benzenesulfonyl)-5-(4-ethylpiperaz...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccc(F)cc2F)CC1 Show InChI InChI=1S/C21H23F2N3O2S/c1-2-24-9-11-25(12-10-24)15-16-3-5-20-17(13-16)7-8-26(20)29(27,28)21-6-4-18(22)14-19(21)23/h3-8,13-14H,2,9-12,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345768 (1-(4-Fluoro benzenesulfonyl)-5-(4-methylpiperazin-...) Show SMILES CN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C20H22FN3O2S/c1-22-10-12-23(13-11-22)15-16-2-7-20-17(14-16)8-9-24(20)27(25,26)19-5-3-18(21)4-6-19/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345759 (1-(4-Isopropyl benzenesulfonyl)-5-(piperazin-1-yl-...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)n1ccc2cc(CN3CCNCC3)ccc12 Show InChI InChI=1S/C22H27N3O2S/c1-17(2)19-4-6-21(7-5-19)28(26,27)25-12-9-20-15-18(3-8-22(20)25)16-24-13-10-23-11-14-24/h3-9,12,15,17,23H,10-11,13-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345767 (1-[4-(Isopropyl benzenesulfonyl)]-5-(4-methylpiper...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)n1ccc2cc(CN3CCN(C)CC3)ccc12 Show InChI InChI=1S/C23H29N3O2S/c1-18(2)20-5-7-22(8-6-20)29(27,28)26-11-10-21-16-19(4-9-23(21)26)17-25-14-12-24(3)13-15-25/h4-11,16,18H,12-15,17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345764 (1-(2,3-Dichloro benzenesulfonyl)-5-(4-methylpipera...) Show SMILES CN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2cccc(Cl)c2Cl)CC1 Show InChI InChI=1S/C20H21Cl2N3O2S/c1-23-9-11-24(12-10-23)14-15-5-6-18-16(13-15)7-8-25(18)28(26,27)19-4-2-3-17(21)20(19)22/h2-8,13H,9-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236533 (2-Fluoro-10-(2-N,N-dimethylaminoethyl)isoindolo[2,...) Show SMILES CN(C)CCC1=C2C(Cc3ccccc23)c2ccc(F)cc12 |t:5| Show InChI InChI=1S/C20H20FN/c1-22(2)10-9-17-18-12-14(21)7-8-16(18)19-11-13-5-3-4-6-15(13)20(17)19/h3-8,12,19H,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24.3	-45.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236521 (2-Phenyl-10-(2-N,N-dimethylaminoethyl)benzo[d]isot...) Show SMILES CN(C)CCC1=C2C(c3ccc(cc13)-c1ccccc1)S(=O)(=O)c1ccccc21 |t:5| Show InChI InChI=1S/C25H23NO2S/c1-26(2)15-14-19-22-16-18(17-8-4-3-5-9-17)12-13-20(22)25-24(19)21-10-6-7-11-23(21)29(25,27)28/h3-13,16,25H,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26.8	-45.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50345770 (1-(4-Chloro benzenesulfonyl)-5-(4-ethylpiperazin-1...) Show SMILES CCN1CCN(Cc2ccc3n(ccc3c2)S(=O)(=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C21H24ClN3O2S/c1-2-23-11-13-24(14-12-23)16-17-3-8-21-18(15-17)9-10-25(21)28(26,27)20-6-4-19(22)5-7-20/h3-10,15H,2,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells				ACS Med Chem Lett 1: 340-344 (2010) Article DOI: 10.1021/ml100101u BindingDB Entry DOI: 10.7270/Q2CR5TPD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236525 (2-Methoxy-10-[(2-N,N-dimethylamino-2-ethyl)ethyl]b...) Show SMILES CCC(CC1=C2C(c3ccc(OC)cc13)S(=O)(=O)c1ccccc21)N(C)C |t:4| Show InChI InChI=1S/C22H25NO3S/c1-5-14(23(2)3)12-19-18-13-15(26-4)10-11-16(18)22-21(19)17-8-6-7-9-20(17)27(22,24)25/h6-11,13-14,22H,5,12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28.3	-44.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236539 (2-Fluoro-7-chloro-10-(2-N,N-dimethylaminoethyl)iso...) Show SMILES CN(C)CCC1=C2C(Cc3cc(Cl)ccc23)c2ccc(F)cc12 |t:5| Show InChI InChI=1S/C20H19ClFN/c1-23(2)8-7-17-18-11-14(22)4-6-16(18)19-10-12-9-13(21)3-5-15(12)20(17)19/h3-6,9,11,19H,7-8,10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	37.6	-44.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236538 (2-Methylthio-10-(2-N,N-dimethylaminoethyl)isoindol...) Show SMILES CSc1ccc2C3Cc4ccccc4C3=C(CCN(C)C)c2c1 |t:16| Show InChI InChI=1S/C21H23NS/c1-22(2)11-10-18-19-13-15(23-3)8-9-17(19)20-12-14-6-4-5-7-16(14)21(18)20/h4-9,13,20H,10-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	49.7	-43.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236522 (2-Bromo-10-[(2-N,N-dimethylamino-2-methyl)ethyl]be...) Show SMILES CC(CC1=C2C(c3ccc(Br)cc13)S(=O)(=O)c1ccccc21)N(C)C |t:3| Show InChI InChI=1S/C20H20BrNO2S/c1-12(22(2)3)10-17-16-11-13(21)8-9-14(16)20-19(17)15-6-4-5-7-18(15)25(20,23)24/h4-9,11-12,20H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	54.1	-43.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236530 (2-Isopropoxy-10-[(2-N,N-dimethylamino-2-methyl)eth...) Show SMILES CC(C)Oc1ccc2C3Cc4ccccc4C3=C(CC(C)N(C)C)c2c1 |t:18| Show InChI InChI=1S/C24H29NO/c1-15(2)26-18-10-11-20-21(14-18)22(12-16(3)25(4)5)24-19-9-7-6-8-17(19)13-23(20)24/h6-11,14-16,23H,12-13H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	73.2	-42.4	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236534 (2-Chloro-10-(2-N,N-dimethylaminoethyl)isoindolo[2,...) Show SMILES CN(C)CCC1=C2C(Cc3ccccc23)c2ccc(Cl)cc12 |t:5| Show InChI InChI=1S/C20H20ClN/c1-22(2)10-9-17-18-12-14(21)7-8-16(18)19-11-13-5-3-4-6-15(13)20(17)19/h3-8,12,19H,9-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	80.7	-42.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236540 (2-Phenyl-10-(2-N,N-dimethylaminoethyl)isoindolo[2,...) Show SMILES CN(C)CCC1=C2C(C(=O)c3ccccc23)c2ccc(cc12)-c1ccccc1 |t:5| Show InChI InChI=1S/C26H23NO/c1-27(2)15-14-21-23-16-18(17-8-4-3-5-9-17)12-13-20(23)25-24(21)19-10-6-7-11-22(19)26(25)28/h3-13,16,25H,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	84.6	-42.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236531 (2-Methoxy-10-(2-N,N-dimethylaminoethyl)isoindolo[2...) Show SMILES COc1ccc2C3Cc4ccccc4C3=C(CCN(C)C)c2c1 |t:16| Show InChI InChI=1S/C21H23NO/c1-22(2)11-10-18-19-13-15(23-3)8-9-17(19)20-12-14-6-4-5-7-16(14)21(18)20/h4-9,13,20H,10-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	86.7	-41.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236520 (10-[(2-N,N-Dimethylamino-2-methyl)ethyl]benzo[d]is...) Show SMILES CC(CC1=C2C(c3ccccc13)S(=O)(=O)c1ccccc21)N(C)C |t:3| Show InChI InChI=1S/C20H21NO2S/c1-13(21(2)3)12-17-14-8-4-5-9-15(14)20-19(17)16-10-6-7-11-18(16)24(20,22)23/h4-11,13,20H,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	87.6	-41.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236537 (10-(2-N,N-dimethylaminoethyl)benzo[d]isoindolo[2,1...) Show SMILES CN(C)CCC1=C2C(Cc3ccccc23)c2c1ccc1ccccc21 |t:5| Show InChI InChI=1S/C24H23N/c1-25(2)14-13-21-20-12-11-16-7-3-5-9-18(16)23(20)22-15-17-8-4-6-10-19(17)24(21)22/h3-12,22H,13-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	92.6	-41.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236523 (2-Methoxy-10-(2-N,N-dimethylaminoethyl)benzo[d]iso...) Show SMILES COc1ccc2C3C(=C(CCN(C)C)c2c1)c1ccccc1S3(=O)=O |t:7| Show InChI InChI=1S/C20H21NO3S/c1-21(2)11-10-14-17-12-13(24-3)8-9-15(17)20-19(14)16-6-4-5-7-18(16)25(20,22)23/h4-9,12,20H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	96	-41.7	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236527 (2-Benzyloxy-10-[(2-N,N-dimethylamino-2-methyl)ethy...) Show SMILES CC(CC1=C2C(c3ccc(OCc4ccccc4)cc13)S(=O)(=O)c1ccccc21)N(C)C |t:3| Show InChI InChI=1S/C27H27NO3S/c1-18(28(2)3)15-24-23-16-20(31-17-19-9-5-4-6-10-19)13-14-21(23)27-26(24)22-11-7-8-12-25(22)32(27,29)30/h4-14,16,18,27H,15,17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	-41.6	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236535 (1-Chloro-10-(2-N,N-dimethylaminoethyl)-4-methyliso...) Show SMILES CN(C)CCC1=C2C(Cc3ccccc23)c2c1c(Cl)ccc2C |t:5| Show InChI InChI=1S/C21H22ClN/c1-13-8-9-18(22)21-16(10-11-23(2)3)20-15-7-5-4-6-14(15)12-17(20)19(13)21/h4-9,17H,10-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	104	-41.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236517 (10-[(2-N,N-Dimethylamino-2-methyl)ethyl]-2-fluorob...) Show SMILES CC(CC1=C2C(c3ccc(F)cc13)S(=O)(=O)c1ccccc21)N(C)C |t:3| Show InChI InChI=1S/C20H20FNO2S/c1-12(22(2)3)10-17-16-11-13(21)8-9-14(16)20-19(17)15-6-4-5-7-18(15)25(20,23)24/h4-9,11-12,20H,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	116	-41.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236519 (4-Chloro-10-(2-N,N-dimethylaminoethyl)benzo[d]isot...) Show SMILES CN(C)CCC1=C2C(c3c1cccc3Cl)S(=O)(=O)c1ccccc21 |t:5| Show InChI InChI=1S/C19H18ClNO2S/c1-21(2)11-10-13-12-7-5-8-15(20)18(12)19-17(13)14-6-3-4-9-16(14)24(19,22)23/h3-9,19H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	126	-41.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236543 (10-(2-N,N-dimethylaminoethyl)isoindolo[2,1-a]indol...) Show SMILES CN(C)CCC1=C2C(C(=O)c3ccccc23)c2ccccc12 |t:5| Show InChI InChI=1S/C20H19NO/c1-21(2)12-11-16-13-7-3-4-8-14(13)19-18(16)15-9-5-6-10-17(15)20(19)22/h3-10,19H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	135	-40.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236536 (2,4-Difluoro-10-(2-N,N-dimethylaminoethyl)isoindol...) Show SMILES CN(C)CCC1=C2C(Cc3ccccc23)c2c1cc(F)cc2F |t:5| Show InChI InChI=1S/C20H19F2N/c1-23(2)8-7-15-16-10-13(21)11-18(22)20(16)17-9-12-5-3-4-6-14(12)19(15)17/h3-6,10-11,17H,7-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	153	-40.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236544 (2-Methoxy-10-[(2-N,N-dimethylamino-2-methyl)ethyl]...) Show SMILES COc1ccc2C3C(=O)c4ccccc4C3=C(CC(C)N(C)C)c2c1 |t:17| Show InChI InChI=1S/C22H23NO2/c1-13(23(2)3)11-19-18-12-14(25-4)9-10-16(18)21-20(19)15-7-5-6-8-17(15)22(21)24/h5-10,12-13,21H,11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	197	-39.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236528 (2-Isopropoxy-10-[(2-N,N-dimethylamino-2-methyl)eth...) Show SMILES CC(C)Oc1ccc2C3C(=C(CC(C)N(C)C)c2c1)c1ccccc1S3(=O)=O |t:9| Show InChI InChI=1S/C23H27NO3S/c1-14(2)27-16-10-11-17-19(13-16)20(12-15(3)24(4)5)22-18-8-6-7-9-21(18)28(25,26)23(17)22/h6-11,13-15,23H,12H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	239	-39.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236515 (10-(2-N,N-Dimethylaminoethyl)benzo[d]isothiazolo[3...) Show SMILES CN(C)CCC1=C2C(c3ccccc13)S(=O)(=O)c1ccccc21 |t:5| Show InChI InChI=1S/C19H19NO2S/c1-20(2)12-11-14-13-7-3-4-8-15(13)19-18(14)16-9-5-6-10-17(16)23(19,21)22/h3-10,19H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	246	-39.2	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM236516 (10-(2-N,N-Dimethylaminoethyl)-2-fluorobenzo[d]isot...) Show SMILES CN(C)CCC1=C2C(c3ccc(F)cc13)S(=O)(=O)c1ccccc21 |t:5| Show InChI InChI=1S/C19H18FNO2S/c1-21(2)10-9-13-16-11-12(20)7-8-14(16)19-18(13)15-5-3-4-6-17(15)24(19,22)23/h3-8,11,19H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	267	-39.0	n/a	n/a	n/a	n/a	n/a	7.4	37
Suven Life Sciences Ltd.					Assay Description In brief, receptor source and radioligand used were human recombinant expressed in HEK-293 cells and [3H] LSD (60-80 Ci/mmol), respectively. The fina...				J Enzyme Inhib Med Chem 27: 443-50 (2012) Article DOI: 10.3109/14756366.2011.595713 BindingDB Entry DOI: 10.7270/Q2HD7TJ5
					More data for this Ligand-Target Pair

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