Found 22 hits with Last Name = 'krasik' and Initial = 'p' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120056
(15-Amino-1-methyl-10-thia-tricyclo[7.5.1.0*2,7*]pe...)Show InChI InChI=1S/C15H21NOS/c1-15-6-2-3-7-18-13(14(15)16)8-10-4-5-11(17)9-12(10)15/h4-5,9,13-14,17H,2-3,6-8,16H2,1H3/t13-,14?,15+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 0.790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120057
(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)Show InChI InChI=1S/C13H19NOS/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120058
(7-Amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-...)Show InChI InChI=1S/C13H19NO2/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50000092
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120053
(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)Show InChI InChI=1S/C14H21NO/c1-4-9-7-10-5-6-11(16)8-12(10)14(2,3)13(9)15/h5-6,8-9,13,16H,4,7,15H2,1-3H3/t9-,13-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50120056
(15-Amino-1-methyl-10-thia-tricyclo[7.5.1.0*2,7*]pe...)Show InChI InChI=1S/C15H21NOS/c1-15-6-2-3-7-18-13(14(15)16)8-10-4-5-11(17)9-12(10)15/h4-5,9,13-14,17H,2-3,6-8,16H2,1H3/t13-,14?,15+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor kappa 1 was determined. |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50000092
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PubMed
| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor kappa 1 was determined. |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50120057
(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)Show InChI InChI=1S/C13H19NOS/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 66 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor kappa 1 was determined. |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50000092
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PubMed
| 113 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor delta 1 was determined |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120061
(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)Show InChI InChI=1S/C14H21NO/c1-4-9-7-10-5-6-11(16)8-12(10)14(2,3)13(9)15/h5-6,8-9,13,16H,4,7,15H2,1-3H3/t9-,13+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 135 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120062
(7-Amino-6-mercapto-8,8-dimethyl-5,6,7,8-tetrahydro...)Show InChI InChI=1S/C12H17NOS/c1-12(2)9-6-8(14)4-3-7(9)5-10(15)11(12)13/h3-4,6,10-11,14-15H,5,13H2,1-2H3/t10-,11-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 163 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50120058
(7-Amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-...)Show InChI InChI=1S/C13H19NO2/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 184 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor kappa 1 was determined. |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120054
(3-Amino-4,4-dimethyl-1,2,3,4-tetrahydro-naphthalen...)Show InChI InChI=1S/C12H17NO2/c1-12(2)9-6-8(14)4-3-7(9)5-10(15)11(12)13/h3-4,6,10-11,14-15H,5,13H2,1-2H3/t10-,11-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 204 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120059
(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)Show InChI InChI=1S/C13H19NOS/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 286 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50120053
(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)Show InChI InChI=1S/C14H21NO/c1-4-9-7-10-5-6-11(16)8-12(10)14(2,3)13(9)15/h5-6,8-9,13,16H,4,7,15H2,1-3H3/t9-,13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 345 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor kappa 1 was determined. |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50120057
(7-Amino-8,8-dimethyl-6-methylsulfanyl-5,6,7,8-tetr...)Show InChI InChI=1S/C13H19NOS/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 349 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor delta 1 was determined |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50120056
(15-Amino-1-methyl-10-thia-tricyclo[7.5.1.0*2,7*]pe...)Show InChI InChI=1S/C15H21NOS/c1-15-6-2-3-7-18-13(14(15)16)8-10-4-5-11(17)9-12(10)15/h4-5,9,13-14,17H,2-3,6-8,16H2,1H3/t13-,14?,15+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor delta 1 was determined |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120055
(7-Amino-6-methanesulfinyl-8,8-dimethyl-5,6,7,8-tet...)Show InChI InChI=1S/C13H19NO2S/c1-13(2)10-7-9(15)5-4-8(10)6-11(12(13)14)17(3)16/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-,17?/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120055
(7-Amino-6-methanesulfinyl-8,8-dimethyl-5,6,7,8-tet...)Show InChI InChI=1S/C13H19NO2S/c1-13(2)10-7-9(15)5-4-8(10)6-11(12(13)14)17(3)16/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-,17?/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50120060
(7-Amino-6-methanesulfonyl-8,8-dimethyl-5,6,7,8-tet...)Show SMILES CC1(C)[C@H](N)[C@@H](Cc2ccc(O)cc12)S(C)(=O)=O Show InChI InChI=1S/C13H19NO3S/c1-13(2)10-7-9(15)5-4-8(10)6-11(12(13)14)18(3,16)17/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-/m1/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity for Opioid receptor mu 1 |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50120053
(7-Amino-6-ethyl-8,8-dimethyl-5,6,7,8-tetrahydro-na...)Show InChI InChI=1S/C14H21NO/c1-4-9-7-10-5-6-11(16)8-12(10)14(2,3)13(9)15/h5-6,8-9,13,16H,4,7,15H2,1-3H3/t9-,13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor delta 1 was determined |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50120058
(7-Amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-...)Show InChI InChI=1S/C13H19NO2/c1-13(2)10-7-9(15)5-4-8(10)6-11(16-3)12(13)14/h4-5,7,11-12,15H,6,14H2,1-3H3/t11-,12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Shire Biochem
Curated by ChEMBL
| Assay Description Binding affinity of the compound for Opioid receptor delta 1 was determined |
Bioorg Med Chem Lett 12: 3141-3 (2002)
BindingDB Entry DOI: 10.7270/Q21N80GS |
More data for this Ligand-Target Pair | |