Compile Data Set for Download or QSAR

Found 134 hits with Last Name = 'lewis' and Initial = 'ml'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50348115 (CHEMBL1800654) Show SMILES CC(C)S(=O)(=O)c1ccc2n(CC3CC3)c(CC(C)(C)C)nc2c1 Show InChI InChI=1S/C19H28N2O2S/c1-13(2)24(22,23)15-8-9-17-16(10-15)20-18(11-19(3,4)5)21(17)12-14-6-7-14/h8-10,13-14H,6-7,11-12H2,1-5H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity at human CB1 receptor				Bioorg Med Chem Lett 21: 4284-7 (2011) Article DOI: 10.1016/j.bmcl.2011.05.063 BindingDB Entry DOI: 10.7270/Q2959HXV
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50348114 (CHEMBL1800653) Show SMILES CN(C)CCn1c(CC(C)(C)C)nc2cc(ccc12)S(=O)(=O)CC(C)(C)O Show InChI InChI=1S/C20H33N3O3S/c1-19(2,3)13-18-21-16-12-15(27(25,26)14-20(4,5)24)8-9-17(16)23(18)11-10-22(6)7/h8-9,12,24H,10-11,13-14H2,1-7H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity at human CB1 receptor				Bioorg Med Chem Lett 21: 4284-7 (2011) Article DOI: 10.1016/j.bmcl.2011.05.063 BindingDB Entry DOI: 10.7270/Q2959HXV
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50348122 (CHEMBL1800168) Show SMILES CCS(=O)(=O)c1ccc2n(CC3CC3)c(nc2c1)C(C)(C)C Show InChI InChI=1S/C17H24N2O2S/c1-5-22(20,21)13-8-9-15-14(10-13)18-16(17(2,3)4)19(15)11-12-6-7-12/h8-10,12H,5-7,11H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity at human CB1 receptor				Bioorg Med Chem Lett 21: 4284-7 (2011) Article DOI: 10.1016/j.bmcl.2011.05.063 BindingDB Entry DOI: 10.7270/Q2959HXV
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227724 (CHEMBL400083 | N-hydroxy-2-methyl-2-{4-[2-methyl-3...) Show SMILES CNCCOc1cccc(c1)-c1ccc(cc1C)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C25H35N3O5S/c1-18-16-20(8-9-23(18)21-6-5-7-22(17-21)33-15-12-26-4)19-10-13-28(14-11-19)34(31,32)25(2,3)24(29)27-30/h5-9,16-17,19,26,30H,10-15H2,1-4H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227723 (2-{4-[3'-(2-amino-ethoxy)-2-methyl-biphenyl-4-yl]-...) Show SMILES Cc1cc(ccc1-c1cccc(OCCN)c1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C24H33N3O5S/c1-17-15-19(7-8-22(17)20-5-4-6-21(16-20)32-14-11-25)18-9-12-27(13-10-18)33(30,31)24(2,3)23(28)26-29/h4-8,15-16,18,29H,9-14,25H2,1-3H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227725 (2-{4-[3'-(2-dimethylamino-ethoxy)-2-methyl-bipheny...) Show SMILES CN(C)CCOc1cccc(c1)-c1ccc(cc1C)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C26H37N3O5S/c1-19-17-21(9-10-24(19)22-7-6-8-23(18-22)34-16-15-28(4)5)20-11-13-29(14-12-20)35(32,33)26(2,3)25(30)27-31/h6-10,17-18,20,31H,11-16H2,1-5H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227722 (CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...) Show SMILES Cc1cc(ccc1-c1cccc(OCCO)c1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C24H32N2O6S/c1-17-15-19(7-8-22(17)20-5-4-6-21(16-20)32-14-13-27)18-9-11-26(12-10-18)33(30,31)24(2,3)23(28)25-29/h4-8,15-16,18,27,29H,9-14H2,1-3H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227709 (CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...) Show SMILES Cc1cc(ccc1-c1cccc(OCCO)n1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C23H31N3O6S/c1-16-15-18(7-8-19(16)20-5-4-6-21(24-20)32-14-13-27)17-9-11-26(12-10-17)33(30,31)23(2,3)22(28)25-29/h4-8,15,17,27,29H,9-14H2,1-3H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227711 (2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine...) Show SMILES CCOc1cccc(c1)-c1ccc(cc1C)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C24H32N2O5S/c1-5-31-21-8-6-7-20(16-21)22-10-9-19(15-17(22)2)18-11-13-26(14-12-18)32(29,30)24(3,4)23(27)25-28/h6-10,15-16,18,28H,5,11-14H2,1-4H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227733 (CHEMBL255030 | N-hydroxy-2-[4-(3'-methoxymethyl-2-...) Show SMILES COCc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:18| Show InChI InChI=1S/C22H26N2O5S/c1-16-12-19(6-7-21(16)20-5-3-4-17(13-20)14-29-2)18-8-10-24(11-9-18)30(27,28)15-22(25)23-26/h3-8,12-13,26H,9-11,14-15H2,1-2H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227728 (2-[4-(2-fluoro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(=CC1)c1ccc(c(F)c1)-c1ccccc1 |c:11| Show InChI InChI=1S/C19H19FN2O4S/c20-18-12-16(6-7-17(18)15-4-2-1-3-5-15)14-8-10-22(11-9-14)27(25,26)13-19(23)21-24/h1-8,12,24H,9-11,13H2,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227717 (CHEMBL251916 | N-hydroxy-2-{4-[3'-(2-methoxy-ethox...) Show SMILES COCCOc1cccc(c1)-c1ccc(cc1C)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C25H34N2O6S/c1-18-16-20(8-9-23(18)21-6-5-7-22(17-21)33-15-14-32-4)19-10-12-27(13-11-19)34(30,31)25(2,3)24(28)26-29/h5-9,16-17,19,29H,10-15H2,1-4H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227710 (2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydr...) Show SMILES CCOc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:18| Show InChI InChI=1S/C22H26N2O5S/c1-3-29-20-6-4-5-19(14-20)21-8-7-18(13-16(21)2)17-9-11-24(12-10-17)30(27,28)15-22(25)23-26/h4-9,13-14,26H,3,10-12,15H2,1-2H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227721 (2-[4-(2,3'-dimethyl-biphenyl-4-yl)-3,6-dihydro-2H-...) Show SMILES Cc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:16| Show InChI InChI=1S/C21H24N2O4S/c1-15-4-3-5-19(12-15)20-7-6-18(13-16(20)2)17-8-10-23(11-9-17)28(26,27)14-21(24)22-25/h3-8,12-13,25H,9-11,14H2,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227734 (CHEMBL254817 | N-hydroxy-2-[4-(3'-methoxy-2-methyl...) Show SMILES COc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:17| Show InChI InChI=1S/C21H24N2O5S/c1-15-12-17(6-7-20(15)18-4-3-5-19(13-18)28-2)16-8-10-23(11-9-16)29(26,27)14-21(24)22-25/h3-8,12-13,25H,9-11,14H2,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227715 (2-(4-biphenyl-4-yl-3,6-dihydro-2H-pyridine-1-sulfo...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(=CC1)c1ccc(cc1)-c1ccccc1 |c:11| Show InChI InChI=1S/C19H20N2O4S/c22-19(20-23)14-26(24,25)21-12-10-18(11-13-21)17-8-6-16(7-9-17)15-4-2-1-3-5-15/h1-10,23H,11-14H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227715 (2-(4-biphenyl-4-yl-3,6-dihydro-2H-pyridine-1-sulfo...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(=CC1)c1ccc(cc1)-c1ccccc1 |c:11| Show InChI InChI=1S/C19H20N2O4S/c22-19(20-23)14-26(24,25)21-12-10-18(11-13-21)17-8-6-16(7-9-17)15-4-2-1-3-5-15/h1-10,23H,11-14H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227719 (CHEMBL254606 | N-hydroxy-2-[4-(2-methyl-biphenyl-4...) Show SMILES Cc1cc(ccc1-c1ccccc1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:15| Show InChI InChI=1S/C20H22N2O4S/c1-15-13-18(7-8-19(15)17-5-3-2-4-6-17)16-9-11-22(12-10-16)27(25,26)14-20(23)21-24/h2-9,13,24H,10-12,14H2,1H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227728 (2-[4-(2-fluoro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(=CC1)c1ccc(c(F)c1)-c1ccccc1 |c:11| Show InChI InChI=1S/C19H19FN2O4S/c20-18-12-16(6-7-17(18)15-4-2-1-3-5-15)14-8-10-22(11-9-14)27(25,26)13-19(23)21-24/h1-8,12,24H,9-11,13H2,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227718 ((R)-3-((S)-1-((S)-2-methoxy-1-phenylethylamino)-3,...) Show SMILES COC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(c(C)c1)-c1ccccc1)CC(O)=O)C(C)(C)C)c1ccccc1 |r| Show InChI InChI=1S/C35H44N2O5/c1-24-21-25(19-20-29(24)26-14-8-6-9-15-26)13-12-18-28(22-31(38)39)33(40)37-32(35(2,3)4)34(41)36-30(23-42-5)27-16-10-7-11-17-27/h6-11,14-17,19-21,28,30,32H,12-13,18,22-23H2,1-5H3,(H,36,41)(H,37,40)(H,38,39)/t28-,30-,32-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227714 (2-(4-biphenyl-4-yl-piperidine-1-sulfonyl)-N-hydrox...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(CC1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H22N2O4S/c22-19(20-23)14-26(24,25)21-12-10-18(11-13-21)17-8-6-16(7-9-17)15-4-2-1-3-5-15/h1-9,18,23H,10-14H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227727 (2-[4-(3'-ethyl-2-methyl-biphenyl-4-yl)-3,6-dihydro...) Show SMILES CCc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:17| Show InChI InChI=1S/C22H26N2O4S/c1-3-17-5-4-6-20(14-17)21-8-7-19(13-16(21)2)18-9-11-24(12-10-18)29(27,28)15-22(25)23-26/h4-9,13-14,26H,3,10-12,15H2,1-2H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227730 (CHEMBL398640 | N-hydroxy-2-[4-(2-methyl-3'-trifluo...) Show SMILES Cc1cc(ccc1-c1cccc(OC(F)(F)F)c1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:20| Show InChI InChI=1S/C21H21F3N2O5S/c1-14-11-16(15-7-9-26(10-8-15)32(29,30)13-20(27)25-28)5-6-19(14)17-3-2-4-18(12-17)31-21(22,23)24/h2-7,11-12,28H,8-10,13H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227716 (2-[4-(2-chloro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(=CC1)c1ccc(c(Cl)c1)-c1ccccc1 |c:11| Show InChI InChI=1S/C19H19ClN2O4S/c20-18-12-16(6-7-17(18)15-4-2-1-3-5-15)14-8-10-22(11-9-14)27(25,26)13-19(23)21-24/h1-8,12,24H,9-11,13H2,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227732 (2-[3-(biphenyl-4-yloxy)-azetidine-1-sulfonyl]-N-hy...) Show SMILES ONC(=O)CS(=O)(=O)N1CC(C1)Oc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H18N2O5S/c20-17(18-21)12-25(22,23)19-10-16(11-19)24-15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,16,21H,10-12H2,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50095314 (CHEMBL3589893) Show SMILES CC(=O)Nc1ccc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl Show InChI InChI=1S/C13H10Cl3N3O/c1-6(20)18-11-3-2-8(13(17)19-11)9-4-7(14)5-10(15)12(9)16/h2-5H,1H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assay				ACS Med Chem Lett 6: 650-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00059 BindingDB Entry DOI: 10.7270/Q23R0VMJ
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227731 (2-(3-biphenyl-4-yl-azetidine-1-sulfonyl)-N-hydroxy...) Show SMILES ONC(=O)CS(=O)(=O)N1CC(C1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H18N2O4S/c20-17(18-21)12-24(22,23)19-10-16(11-19)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,16,21H,10-12H2,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227726 (2-[(2-biphenyl-4-yl-ethyl)-methyl-sulfamoyl]-N-hyd...) Show SMILES CN(CCc1ccc(cc1)-c1ccccc1)S(=O)(=O)CC(=O)NO Show InChI InChI=1S/C17H20N2O4S/c1-19(24(22,23)13-17(20)18-21)12-11-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10,21H,11-13H2,1H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227730 (CHEMBL398640 | N-hydroxy-2-[4-(2-methyl-3'-trifluo...) Show SMILES Cc1cc(ccc1-c1cccc(OC(F)(F)F)c1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:20| Show InChI InChI=1S/C21H21F3N2O5S/c1-14-11-16(15-7-9-26(10-8-15)32(29,30)13-20(27)25-28)5-6-19(14)17-3-2-4-18(12-17)31-21(22,23)24/h2-7,11-12,28H,8-10,13H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227720 (2-[(3-biphenyl-4-yl-propyl)-methyl-sulfamoyl]-N-hy...) Show SMILES CN(CCCc1ccc(cc1)-c1ccccc1)S(=O)(=O)CC(=O)NO Show InChI InChI=1S/C18H22N2O4S/c1-20(25(23,24)14-18(21)19-22)13-5-6-15-9-11-17(12-10-15)16-7-3-2-4-8-16/h2-4,7-12,22H,5-6,13-14H2,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	174	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227723 (2-{4-[3'-(2-amino-ethoxy)-2-methyl-biphenyl-4-yl]-...) Show SMILES Cc1cc(ccc1-c1cccc(OCCN)c1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C24H33N3O5S/c1-17-15-19(7-8-22(17)20-5-4-6-21(16-20)32-14-11-25)18-9-12-27(13-10-18)33(30,31)24(2,3)23(28)26-29/h4-8,15-16,18,29H,9-14,25H2,1-3H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50095311 (CHEMBL3589904) Show SMILES COc1ccc(Cl)c(c1)-c1ccc(NC(=O)c2ccnn2C)nc1N Show InChI InChI=1S/C17H16ClN5O2/c1-23-14(7-8-20-23)17(24)22-15-6-4-11(16(19)21-15)12-9-10(25-2)3-5-13(12)18/h3-9H,1-2H3,(H3,19,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiology				ACS Med Chem Lett 6: 650-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00059 BindingDB Entry DOI: 10.7270/Q23R0VMJ
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50095310 (CHEMBL3589894) Show SMILES CNC(=O)c1ccc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl Show InChI InChI=1S/C13H10Cl3N3O/c1-18-13(20)10-3-2-7(12(17)19-10)8-4-6(14)5-9(15)11(8)16/h2-5H,1H3,(H2,17,19)(H,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiology				ACS Med Chem Lett 6: 650-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00059 BindingDB Entry DOI: 10.7270/Q23R0VMJ
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227733 (CHEMBL255030 | N-hydroxy-2-[4-(3'-methoxymethyl-2-...) Show SMILES COCc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:18| Show InChI InChI=1S/C22H26N2O5S/c1-16-12-19(6-7-21(16)20-5-3-4-17(13-20)14-29-2)18-8-10-24(11-9-18)30(27,28)15-22(25)23-26/h3-8,12-13,26H,9-11,14-15H2,1-2H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227724 (CHEMBL400083 | N-hydroxy-2-methyl-2-{4-[2-methyl-3...) Show SMILES CNCCOc1cccc(c1)-c1ccc(cc1C)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C25H35N3O5S/c1-18-16-20(8-9-23(18)21-6-5-7-22(17-21)33-15-12-26-4)19-10-13-28(14-11-19)34(31,32)25(2,3)24(29)27-30/h5-9,16-17,19,26,30H,10-15H2,1-4H3,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227729 (CHEMBL400463 | N-hydroxy-2-(4-(4-phenoxyphenyl)pip...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(CC1)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C19H22N2O5S/c22-19(20-23)14-27(24,25)21-12-10-16(11-13-21)15-6-8-18(9-7-15)26-17-4-2-1-3-5-17/h1-9,16,23H,10-14H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227734 (CHEMBL254817 | N-hydroxy-2-[4-(3'-methoxy-2-methyl...) Show SMILES COc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:17| Show InChI InChI=1S/C21H24N2O5S/c1-15-12-17(6-7-20(15)18-4-3-5-19(13-18)28-2)16-8-10-23(11-9-16)29(26,27)14-21(24)22-25/h3-8,12-13,25H,9-11,14H2,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50095312 (CHEMBL2324355) Show SMILES Cc1nocc1C(=O)Nc1ccc(c(N)n1)-c1ccccc1OC(F)(F)F Show InChI InChI=1S/C17H13F3N4O3/c1-9-12(8-26-24-9)16(25)23-14-7-6-11(15(21)22-14)10-4-2-3-5-13(10)27-17(18,19)20/h2-8H,1H3,(H3,21,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8/beta1 expressed in HEK293 cells by manual patch clamp electrophysiology				ACS Med Chem Lett 6: 650-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00059 BindingDB Entry DOI: 10.7270/Q23R0VMJ
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227722 (CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...) Show SMILES Cc1cc(ccc1-c1cccc(OCCO)c1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C24H32N2O6S/c1-17-15-19(7-8-22(17)20-5-4-6-21(16-20)32-14-13-27)18-9-11-26(12-10-18)33(30,31)24(2,3)23(28)25-29/h4-8,15-16,18,27,29H,9-14H2,1-3H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227719 (CHEMBL254606 | N-hydroxy-2-[4-(2-methyl-biphenyl-4...) Show SMILES Cc1cc(ccc1-c1ccccc1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:15| Show InChI InChI=1S/C20H22N2O4S/c1-15-13-18(7-8-19(15)17-5-3-2-4-6-17)16-9-11-22(12-10-16)27(25,26)14-20(23)21-24/h2-9,13,24H,10-12,14H2,1H3,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227735 (2-(biphenyl-4-ylmethyl-methyl-sulfamoyl)-N-hydroxy...) Show SMILES CN(Cc1ccc(cc1)-c1ccccc1)S(=O)(=O)CC(=O)NO Show InChI InChI=1S/C16H18N2O4S/c1-18(23(21,22)12-16(19)17-20)11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10,20H,11-12H2,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50227722 (CHEMBL398641 | N-hydroxy-2-{4-[3'-(2-hydroxy-ethox...) Show SMILES Cc1cc(ccc1-c1cccc(OCCO)c1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C24H32N2O6S/c1-17-15-19(7-8-22(17)20-5-4-6-21(16-20)32-14-13-27)18-9-11-26(12-10-18)33(30,31)24(2,3)23(28)25-29/h4-8,15-16,18,27,29H,9-14H2,1-3H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	406	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50227713 (2-[4-(2-ethyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridi...) Show SMILES CCc1cc(ccc1-c1ccccc1)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:16| Show InChI InChI=1S/C21H24N2O4S/c1-2-16-14-19(8-9-20(16)18-6-4-3-5-7-18)17-10-12-23(13-11-17)28(26,27)15-21(24)22-25/h3-10,14,25H,2,11-13,15H2,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227711 (2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-piperidine...) Show SMILES CCOc1cccc(c1)-c1ccc(cc1C)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C24H32N2O5S/c1-5-31-21-8-6-7-20(16-21)22-10-9-19(15-17(22)2)18-11-13-26(14-12-18)32(29,30)24(3,4)23(27)25-28/h6-10,15-16,18,28H,5,11-14H2,1-4H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50095331 (CHEMBL3589903) Show SMILES COc1ccc(Cl)c(c1)-c1ccc(NC(=O)c2conc2C)nc1N Show InChI InChI=1S/C17H15ClN4O3/c1-9-13(8-25-22-9)17(23)21-15-6-4-11(16(19)20-15)12-7-10(24-2)3-5-14(12)18/h3-8H,1-2H3,(H3,19,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assay				ACS Med Chem Lett 6: 650-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00059 BindingDB Entry DOI: 10.7270/Q23R0VMJ
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227709 (CHEMBL251917 | N-hydroxy-2-(4-(4-(6-(2-hydroxyetho...) Show SMILES Cc1cc(ccc1-c1cccc(OCCO)n1)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C23H31N3O6S/c1-16-15-18(7-8-19(16)20-5-4-6-21(24-20)32-14-13-27)17-9-11-26(12-10-17)33(30,31)23(2,3)22(28)25-29/h4-8,15,17,27,29H,9-14H2,1-3H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	529	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50095312 (CHEMBL2324355) Show SMILES Cc1nocc1C(=O)Nc1ccc(c(N)n1)-c1ccccc1OC(F)(F)F Show InChI InChI=1S/C17H13F3N4O3/c1-9-12(8-26-24-9)16(25)23-14-7-6-11(15(21)22-14)10-4-2-3-5-13(10)27-17(18,19)20/h2-8H,1H3,(H3,21,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assay				ACS Med Chem Lett 6: 650-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00059 BindingDB Entry DOI: 10.7270/Q23R0VMJ
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227725 (2-{4-[3'-(2-dimethylamino-ethoxy)-2-methyl-bipheny...) Show SMILES CN(C)CCOc1cccc(c1)-c1ccc(cc1C)C1CCN(CC1)S(=O)(=O)C(C)(C)C(=O)NO Show InChI InChI=1S/C26H37N3O5S/c1-19-17-21(9-10-24(19)22-7-6-8-23(18-22)34-16-15-28(4)5)20-11-13-29(14-12-20)35(32,33)26(2,3)25(30)27-31/h6-10,17-18,20,31H,11-16H2,1-5H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	534	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227716 (2-[4-(2-chloro-biphenyl-4-yl)-3,6-dihydro-2H-pyrid...) Show SMILES ONC(=O)CS(=O)(=O)N1CCC(=CC1)c1ccc(c(Cl)c1)-c1ccccc1 |c:11| Show InChI InChI=1S/C19H19ClN2O4S/c20-18-12-16(6-7-17(18)15-4-2-1-3-5-15)14-8-10-22(11-9-14)27(25,26)13-19(23)21-24/h1-8,12,24H,9-11,13H2,(H,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
Sodium channel protein type 10 subunit alpha (Homo sapiens (Human))	BDBM50095329 (CHEMBL3589901) Show SMILES Cc1nocc1C(=O)Nc1ccc(c(N)n1)-c1cc(Cl)cc(Cl)c1Cl Show InChI InChI=1S/C16H11Cl3N4O2/c1-7-11(6-25-23-7)16(24)22-13-3-2-9(15(20)21-13)10-4-8(17)5-12(18)14(10)19/h2-6H,1H3,(H3,20,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.8 expressed in HEK293 cells assessed as reduction in blue fluorescent signal by VSP-FRET assay				ACS Med Chem Lett 6: 650-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00059 BindingDB Entry DOI: 10.7270/Q23R0VMJ
					More data for this Ligand-Target Pair

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