Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50613517 (CHEMBL5273346) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21995 (5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0900 | -56.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM50062858 (8-Cyclopentyl-3-(2-fluoro-propyl)-1-propyl-3,7-dih...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50185339 (3-(2,6-difluorophenyl)-5-[4-fluoro-3-(3-fluoropyri...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 | J Med Chem 49: 2600-10 (2006) Article DOI: 10.1021/jm051144x BindingDB Entry DOI: 10.7270/Q29Z94HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180003 (4,2-difluoro-5-[7-(1-hydroxy-1-methylethyl)imidazo...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM164488 (US9066954, 373) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.100 | -57.5 | n/a | n/a | n/a | n/a | n/a | 8.0 | 27 |
Amgen Inc. US Patent | Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri... | US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179995 (3'-(7-methyl-imidazo[1,2-a]pyrimidin-3-yl)-bipheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50613518 (CHEMBL5289754) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179924 (4-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 0.155 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM21173 (1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 0.155 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50613552 (CHEMBL5281808) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM50062852 (8-Cyclopentyl-3-(3-fluoro-propyl)-1-propyl-3,7-dih...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.183 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180004 (2-fluoro-5-(7-trifluoromethylimidazo[1,2-a]pyrimid...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50176771 (7-(1,1-dimethyleth-1-yl)-3-(2-fluoro-phenyl)-6-(2-...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180007 (3'-(7-trifluoromethyl-imidazo[1,2-a]pyrimidin-3-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM50062853 (8-Cyclopentyl-1-(3-fluoro-propyl)-3,7-dihydro-puri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.216 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50613546 (CHEMBL5273114) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM50062856 (8-Cyclopentyl-3-((E)-3-iodo-propenyl)-1-propyl-3,7...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.237 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50613519 (CHEMBL5281912) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180002 (5,2-difluoro-5-(7-trifluoromethylimidazo[1,2-a]pyr...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50176771 (7-(1,1-dimethyleth-1-yl)-3-(2-fluoro-phenyl)-6-(2-...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha1 in combination with beta-3-gamma-2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50613478 (CHEMBL5273273) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179924 (4-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM50062859 (8-Cyclopentyl-1-ethoxymethyl-3-propyl-3,7-dihydro-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.286 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50148320 (2-(4-Chloro-phenyl)-2,5,6,7,8,9-hexahydro-pyrazolo...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [3H]-Ro- 15-1788 binding to human GABA-A receptor alpha1-beta3-gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 15: 4998-5002 (2005) Article DOI: 10.1016/j.bmcl.2005.08.006 BindingDB Entry DOI: 10.7270/Q2W66K93 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxytocin receptor (Homo sapiens (Human)) | BDBM50332720 ((S)-1-((4R,7S,10S,13S,16S,19R)-4-amino-16-(2-amino...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Displacement of [3H]OT from oxytocin receptor expressed in COS1 cells | J Med Chem 53: 8585-96 (2010) Article DOI: 10.1021/jm100989w BindingDB Entry DOI: 10.7270/Q2CC10X9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50613548 (CHEMBL5286081) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | UniChem | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50185339 (3-(2,6-difluorophenyl)-5-[4-fluoro-3-(3-fluoropyri...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 | J Med Chem 49: 2600-10 (2006) Article DOI: 10.1021/jm051144x BindingDB Entry DOI: 10.7270/Q29Z94HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50176771 (7-(1,1-dimethyleth-1-yl)-3-(2-fluoro-phenyl)-6-(2-...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha2 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50176771 (7-(1,1-dimethyleth-1-yl)-3-(2-fluoro-phenyl)-6-(2-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM164473 (US9066954, 302) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.300 | -54.7 | n/a | n/a | n/a | n/a | n/a | 8.0 | 27 |
Amgen Inc. US Patent | Assay Description A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri... | US Patent US9066954 (2015) BindingDB Entry DOI: 10.7270/Q2N878JD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180382 (7-(trifluoromethyl)-3-(6-(trifluoromethyl)pyridin-...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180388 (3-(6-bromopyridin-2-yl)-7-(trifluoromethyl)imidazo...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM21992 (5-{[(3R)-3-hydroxypyrrolidin-1-yl]carbonyl}-3-meth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.310 | -53.7 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
AstraZeneca | Assay Description Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ... | J Med Chem 50: 254-63 (2007) Article DOI: 10.1021/jm060995h BindingDB Entry DOI: 10.7270/Q2GT5KGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (BOVINE) | BDBM50011842 (8-Cyclopentyl-3-methyl-1-propyl-3,7-dihydro-purine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Forschungszentrum Jülich GmbH Curated by ChEMBL | Assay Description Displacement of [3H]-CPX from Adenosine A1 receptor of bovine brain cerebral cortex membranes | J Med Chem 41: 555-63 (1998) Article DOI: 10.1021/jm9705465 BindingDB Entry DOI: 10.7270/Q2RX9B60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179919 (2-(3-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179923 (4-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180007 (3'-(7-trifluoromethyl-imidazo[1,2-a]pyrimidin-3-yl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180007 (3'-(7-trifluoromethyl-imidazo[1,2-a]pyrimidin-3-yl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180004 (2-fluoro-5-(7-trifluoromethylimidazo[1,2-a]pyrimid...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180379 (2-(6-(7-(trifluoromethyl)imidazo[1,2-a]pyrimidin-3...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1175-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.112 BindingDB Entry DOI: 10.7270/Q2FN15SZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179995 (3'-(7-methyl-imidazo[1,2-a]pyrimidin-3-yl)-bipheny...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50180001 (6,2-difluoro-5-(7-trifluoromethylimidazo[1,2-a]pyr...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179995 (3'-(7-methyl-imidazo[1,2-a]pyrimidin-3-yl)-bipheny...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp Laboratory Curated by ChEMBL | Assay Description Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha1 in combination with beta-3-gamma-2 expressed in L(tk-) cells | J Med Chem 49: 35-8 (2006) Article DOI: 10.1021/jm051065l BindingDB Entry DOI: 10.7270/Q21R6RBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50185335 (5-[3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl]-3-...) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 | J Med Chem 49: 2600-10 (2006) Article DOI: 10.1021/jm051144x BindingDB Entry DOI: 10.7270/Q29Z94HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50002184 (CHEMBL415330 | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-A...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50185339 (3-(2,6-difluorophenyl)-5-[4-fluoro-3-(3-fluoropyri...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 | J Med Chem 49: 2600-10 (2006) Article DOI: 10.1021/jm051144x BindingDB Entry DOI: 10.7270/Q29Z94HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179925 (2-(3-(4-fluoro-3-(3-fluoropyridin-2-yl)phenyl)imid...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50179918 (2-(3-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells | Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW | |||||||||||
More data for this Ligand-Target Pair |
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