Compile Data Set for Download or QSAR

Found 89 hits with Last Name = 'luedtke' and Initial = 'gr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315949 ((S)-N-(4-aminobutyl)-N-(2-(1-phenylethylamino)pyri...) Show SMILES C[C@H](Nc1nccc(n1)N(CCCCN)C(=O)c1ccc2OCCc2c1)c1ccccc1 |r| Show InChI InChI=1S/C25H29N5O2/c1-18(19-7-3-2-4-8-19)28-25-27-14-11-23(29-25)30(15-6-5-13-26)24(31)21-9-10-22-20(17-21)12-16-32-22/h2-4,7-11,14,17-18H,5-6,12-13,15-16,26H2,1H3,(H,27,28,29)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306491 (2-(6-chloro-5-((2R,5S)-4-(1-(4-fluorophenyl)ethyl)...) Show SMILES CC(N1C[C@@H](C)N(C[C@@H]1C)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C)c1ccc(F)cc1 |r| Show InChI InChI=1S/C28H32ClFN4O3/c1-16-14-34(17(2)13-33(16)18(3)19-7-9-20(30)10-8-19)27(36)22-11-21-23(26(35)28(37)31(4)5)15-32(6)25(21)12-24(22)29/h7-12,15-18H,13-14H2,1-6H3/t16-,17+,18?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50266947 (2-(6-chloro-5-((2R,5S)-4-(4-fluorobenzyl)-2,5-dime...) Show SMILES C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C |r| Show InChI InChI=1S/C27H30ClFN4O3/c1-16-13-33(17(2)12-32(16)14-18-6-8-19(29)9-7-18)26(35)21-10-20-22(25(34)27(36)30(3)4)15-31(5)24(20)11-23(21)28/h6-11,15-17H,12-14H2,1-5H3/t16-,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306493 (2-(5-((2R,5S)-4-benzhydryl-2,5-dimethylpiperazine-...) Show SMILES C[C@H]1CN([C@H](C)CN1C(c1ccccc1)c1ccccc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C |r| Show InChI InChI=1S/C33H35ClN4O3/c1-21-19-38(22(2)18-37(21)30(23-12-8-6-9-13-23)24-14-10-7-11-15-24)32(40)26-16-25-27(31(39)33(41)35(3)4)20-36(5)29(25)17-28(26)34/h6-17,20-22,30H,18-19H2,1-5H3/t21-,22+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50309525 (2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...) Show SMILES COc1cc2[nH]cc(C(=O)C(=O)N(C)C)c2cc1C(=O)N1CCC(Cc2ccc(F)cc2)CC1 Show InChI InChI=1S/C26H28FN3O4/c1-29(2)26(33)24(31)21-15-28-22-14-23(34-3)20(13-19(21)22)25(32)30-10-8-17(9-11-30)12-16-4-6-18(27)7-5-16/h4-7,13-15,17,28H,8-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Scios, Inc Curated by ChEMBL					Assay Description Inhibition of human p38alpha after 60 mins				Bioorg Med Chem Lett 20: 1059-62 (2010) Article DOI: 10.1016/j.bmcl.2009.12.031 BindingDB Entry DOI: 10.7270/Q2J38SP4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50309525 (2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...) Show SMILES COc1cc2[nH]cc(C(=O)C(=O)N(C)C)c2cc1C(=O)N1CCC(Cc2ccc(F)cc2)CC1 Show InChI InChI=1S/C26H28FN3O4/c1-29(2)26(33)24(31)21-15-28-22-14-23(34-3)20(13-19(21)22)25(32)30-10-8-17(9-11-30)12-16-4-6-18(27)7-5-16/h4-7,13-15,17,28H,8-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2556-9 (2010) Article DOI: 10.1016/j.bmcl.2010.02.088 BindingDB Entry DOI: 10.7270/Q2VT1S84
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315959 (CHEMBL1091614 | N-(4-aminobutyl)-N-(2-(4-hydroxycy...) Show SMILES NCCCCN(C(=O)c1ccc2OCCc2c1)c1ccnc(NC2CCC(O)CC2)n1 |(4.21,-2.5,;3.12,-3.6,;1.79,-2.83,;.46,-3.6,;-.87,-2.84,;-2.2,-3.61,;-2.2,-5.15,;-.87,-5.91,;-3.53,-5.92,;-3.52,-7.45,;-4.85,-8.22,;-6.19,-7.46,;-7.66,-7.94,;-8.57,-6.69,;-7.66,-5.44,;-6.19,-5.92,;-4.86,-5.14,;-3.54,-2.84,;-4.87,-3.61,;-6.21,-2.84,;-6.21,-1.3,;-4.88,-.53,;-4.88,1.01,;-3.55,1.78,;-2.21,1.02,;-.88,1.79,;-.88,3.33,;.45,4.09,;-2.21,4.1,;-3.55,3.33,;-3.54,-1.29,)| Show InChI InChI=1S/C23H31N5O3/c24-11-1-2-13-28(22(30)17-3-8-20-16(15-17)10-14-31-20)21-9-12-25-23(27-21)26-18-4-6-19(29)7-5-18/h3,8-9,12,15,18-19,29H,1-2,4-7,10-11,13-14,24H2,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315931 ((S)-N-ethyl-3-methyl-N-(2-(1-phenylethylamino)pyri...) Show SMILES CCN(C(=O)c1cccc(C)c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C22H24N4O/c1-4-26(21(27)19-12-8-9-16(2)15-19)20-13-14-23-22(25-20)24-17(3)18-10-6-5-7-11-18/h5-15,17H,4H2,1-3H3,(H,23,24,25)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315958 (CHEMBL1089655 | N-(4-aminobutyl)-N-(2-(isopropylam...) Show SMILES CC(C)Nc1nccc(n1)N(CCCCN)C(=O)c1ccc2OCCc2c1 Show InChI InChI=1S/C20H27N5O2/c1-14(2)23-20-22-10-7-18(24-20)25(11-4-3-9-21)19(26)16-5-6-17-15(13-16)8-12-27-17/h5-7,10,13-14H,3-4,8-9,11-12,21H2,1-2H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315917 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1ccc2OCCc2c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H24N4O2/c1-3-27(22(28)19-9-10-20-18(15-19)12-14-29-20)21-11-13-24-23(26-21)25-16(2)17-7-5-4-6-8-17/h4-11,13,15-16H,3,12,14H2,1-2H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50309524 (2-(6-chloro-5-(4-(4-fluorobenzyl)piperidine-1-carb...) Show SMILES CN(C)C(=O)C(=O)c1c[nH]c2cc(Cl)c(cc12)C(=O)N1CCC(Cc2ccc(F)cc2)CC1 Show InChI InChI=1S/C25H25ClFN3O3/c1-29(2)25(33)23(31)20-14-28-22-13-21(26)19(12-18(20)22)24(32)30-9-7-16(8-10-30)11-15-3-5-17(27)6-4-15/h3-6,12-14,16,28H,7-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Scios, Inc Curated by ChEMBL					Assay Description Inhibition of human p38alpha after 60 mins				Bioorg Med Chem Lett 20: 1059-62 (2010) Article DOI: 10.1016/j.bmcl.2009.12.031 BindingDB Entry DOI: 10.7270/Q2J38SP4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50132378 (((1S,3R)-4-Benzyl-2,5-dimethyl-piperazin-1-yl)-(6-...) Show SMILES COc1cc2[nH]ccc2cc1C(=O)N1C[C@H](C)N(Cc2ccccc2)C[C@H]1C |r| Show InChI InChI=1S/C23H27N3O2/c1-16-14-26(17(2)13-25(16)15-18-7-5-4-6-8-18)23(27)20-11-19-9-10-24-21(19)12-22(20)28-3/h4-12,16-17,24H,13-15H2,1-3H3/t16-,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 13: 3087-90 (2003) BindingDB Entry DOI: 10.7270/Q2S181XN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50132378 (((1S,3R)-4-Benzyl-2,5-dimethyl-piperazin-1-yl)-(6-...) Show SMILES COc1cc2[nH]ccc2cc1C(=O)N1C[C@H](C)N(Cc2ccccc2)C[C@H]1C |r| Show InChI InChI=1S/C23H27N3O2/c1-16-14-26(17(2)13-25(16)15-18-7-5-4-6-8-18)23(27)20-11-19-9-10-24-21(19)12-22(20)28-3/h4-12,16-17,24H,13-15H2,1-3H3/t16-,17+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 13: 3087-90 (2003) BindingDB Entry DOI: 10.7270/Q2S181XN
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315951 (CHEMBL1093834 | N-(2-(isopropylamino)pyrimidin-4-y...) Show SMILES CC(C)Nc1nccc(n1)N(CC1CCNCC1)C(=O)c1ccc2OCCc2c1 Show InChI InChI=1S/C22H29N5O2/c1-15(2)25-22-24-11-7-20(26-22)27(14-16-5-9-23-10-6-16)21(28)18-3-4-19-17(13-18)8-12-29-19/h3-4,7,11,13,15-16,23H,5-6,8-10,12,14H2,1-2H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306492 (2-(5-((2R,5S)-4-(bis(4-fluorophenyl)methyl)-2,5-di...) Show SMILES C[C@H]1CN([C@H](C)CN1C(c1ccc(F)cc1)c1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C |r| Show InChI InChI=1S/C33H33ClF2N4O3/c1-19-17-40(20(2)16-39(19)30(21-6-10-23(35)11-7-21)22-8-12-24(36)13-9-22)32(42)26-14-25-27(31(41)33(43)37(3)4)18-38(5)29(25)15-28(26)34/h6-15,18-20,30H,16-17H2,1-5H3/t19-,20+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315960 ((S)-N-(4-aminobutyl)-N-(2-(1-methoxypropan-2-ylami...) Show SMILES COC[C@H](C)Nc1nccc(n1)N(CCCCN)C(=O)c1ccc2OCCc2c1 |r| Show InChI InChI=1S/C21H29N5O3/c1-15(14-28-2)24-21-23-10-7-19(25-21)26(11-4-3-9-22)20(27)17-5-6-18-16(13-17)8-12-29-18/h5-7,10,13,15H,3-4,8-9,11-12,14,22H2,1-2H3,(H,23,24,25)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315938 ((S)-N-ethyl-2-fluoro-5-methyl-N-(2-(1-phenylethyla...) Show SMILES CCN(C(=O)c1cc(C)ccc1F)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C22H23FN4O/c1-4-27(21(28)18-14-15(2)10-11-19(18)23)20-12-13-24-22(26-20)25-16(3)17-8-6-5-7-9-17/h5-14,16H,4H2,1-3H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306494 (2-(6-chloro-5-((2R,5S)-4-(2,3-dihydro-1H-inden-1-y...) Show SMILES C[C@H]1CN([C@H](C)CN1C1CCc2ccccc12)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C |r| Show InChI InChI=1S/C29H33ClN4O3/c1-17-15-34(18(2)14-33(17)25-11-10-19-8-6-7-9-20(19)25)28(36)22-12-21-23(27(35)29(37)31(3)4)16-32(5)26(21)13-24(22)30/h6-9,12-13,16-18,25H,10-11,14-15H2,1-5H3/t17-,18+,25?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315937 ((S)-N-ethyl-4-fluoro-3-methyl-N-(2-(1-phenylethyla...) Show SMILES CCN(C(=O)c1ccc(F)c(C)c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C22H23FN4O/c1-4-27(21(28)18-10-11-19(23)15(2)14-18)20-12-13-24-22(26-20)25-16(3)17-8-6-5-7-9-17/h5-14,16H,4H2,1-3H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315922 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1ccc2CCCc2c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C24H26N4O/c1-3-28(23(29)21-13-12-19-10-7-11-20(19)16-21)22-14-15-25-24(27-22)26-17(2)18-8-5-4-6-9-18/h4-6,8-9,12-17H,3,7,10-11H2,1-2H3,(H,25,26,27)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306496 (2-(6-chloro-5-((2R,5S)-4-(1-cyano-1-(4-fluoropheny...) Show SMILES C[C@@H]1CN([C@@H](C)CN1C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C)C(C)(C#N)c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H31ClFN5O3/c1-17-14-36(29(3,16-32)19-7-9-20(31)10-8-19)18(2)13-35(17)27(38)22-11-21-23(26(37)28(39)33(4)5)15-34(6)25(21)12-24(22)30/h7-12,15,17-18H,13-14H2,1-6H3/t17-,18+,29?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306497 (2-(6-chloro-5-((2R,5S)-4-(7-chloro-1H-indazol-3-yl...) Show SMILES C[C@@H]1CN([C@@H](C)CN1C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C)c1n[nH]c2c(Cl)cccc12 |r| Show InChI InChI=1S/C27H28Cl2N6O3/c1-14-12-35(15(2)11-34(14)25-16-7-6-8-20(28)23(16)30-31-25)26(37)18-9-17-19(24(36)27(38)32(3)4)13-33(5)22(17)10-21(18)29/h6-10,13-15H,11-12H2,1-5H3,(H,30,31)/t14-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315943 ((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-(pi...) Show SMILES C[C@H](Nc1nccc(n1)N(CC1CCNCC1)C(=O)c1ccc2OCCc2c1)c1ccccc1 |r| Show InChI InChI=1S/C27H31N5O2/c1-19(21-5-3-2-4-6-21)30-27-29-15-11-25(31-27)32(18-20-9-13-28-14-10-20)26(33)23-7-8-24-22(17-23)12-16-34-24/h2-8,11,15,17,19-20,28H,9-10,12-14,16,18H2,1H3,(H,29,30,31)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50309531 (2-(5-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-6-m...) Show SMILES COc1nc2[nH]cc(C(=O)C(=O)N(C)C)c2cc1C(=O)N1CCC(Cc2ccc(F)cc2)CC1 Show InChI InChI=1S/C25H27FN4O4/c1-29(2)25(33)21(31)20-14-27-22-18(20)13-19(23(28-22)34-3)24(32)30-10-8-16(9-11-30)12-15-4-6-17(26)7-5-15/h4-7,13-14,16H,8-12H2,1-3H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Scios, Inc Curated by ChEMBL					Assay Description Inhibition of human p38alpha after 60 mins				Bioorg Med Chem Lett 20: 1059-62 (2010) Article DOI: 10.1016/j.bmcl.2009.12.031 BindingDB Entry DOI: 10.7270/Q2J38SP4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315916 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1ccc2ccccc2c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C25H24N4O/c1-3-29(24(30)22-14-13-20-11-7-8-12-21(20)17-22)23-15-16-26-25(28-23)27-18(2)19-9-5-4-6-10-19/h4-18H,3H2,1-2H3,(H,26,27,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315936 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1cccc(c1)C(F)(F)F)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C22H21F3N4O/c1-3-29(20(30)17-10-7-11-18(14-17)22(23,24)25)19-12-13-26-21(28-19)27-15(2)16-8-5-4-6-9-16/h4-15H,3H2,1-2H3,(H,26,27,28)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315934 ((S)-N,3-diethyl-N-(2-(1-phenylethylamino)pyrimidin...) Show SMILES CCN(C(=O)c1cccc(CC)c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H26N4O/c1-4-18-10-9-13-20(16-18)22(28)27(5-2)21-14-15-24-23(26-21)25-17(3)19-11-7-6-8-12-19/h6-17H,4-5H2,1-3H3,(H,24,25,26)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315920 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1ccc2occc2c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H22N4O2/c1-3-27(22(28)19-9-10-20-18(15-19)12-14-29-20)21-11-13-24-23(26-21)25-16(2)17-7-5-4-6-8-17/h4-16H,3H2,1-2H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315919 ((S)-N-(3-(methylsulfonyl)propyl)-N-(2-(1-phenyleth...) Show SMILES C[C@H](Nc1nccc(n1)N(CCCS(C)(=O)=O)C(=O)c1ccc2OCCc2c1)c1ccccc1 |r| Show InChI InChI=1S/C25H28N4O4S/c1-18(19-7-4-3-5-8-19)27-25-26-13-11-23(28-25)29(14-6-16-34(2,31)32)24(30)21-9-10-22-20(17-21)12-15-33-22/h3-5,7-11,13,17-18H,6,12,14-16H2,1-2H3,(H,26,27,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315933 ((S)-N-ethyl-2,3-dimethyl-N-(2-(1-phenylethylamino)...) Show SMILES CCN(C(=O)c1cccc(C)c1C)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H26N4O/c1-5-27(22(28)20-13-9-10-16(2)17(20)3)21-14-15-24-23(26-21)25-18(4)19-11-7-6-8-12-19/h6-15,18H,5H2,1-4H3,(H,24,25,26)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315929 ((S)-3-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...) Show SMILES CCN(C(=O)c1cccc(Cl)c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C21H21ClN4O/c1-3-26(20(27)17-10-7-11-18(22)14-17)19-12-13-23-21(25-19)24-15(2)16-8-5-4-6-9-16/h4-15H,3H2,1-2H3,(H,23,24,25)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315921 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1cccc2CCOc12)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H24N4O2/c1-3-27(22(28)19-11-7-10-18-13-15-29-21(18)19)20-12-14-24-23(26-20)25-16(2)17-8-5-4-6-9-17/h4-12,14,16H,3,13,15H2,1-2H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50309529 (2-(3-(4-(4-fluorobenzyl)piperidine-1-carbonyl)-2-m...) Show SMILES CN(C)C(=O)C(=O)c1ccc2[nH]c(C)c(C(=O)N3CCC(Cc4ccc(F)cc4)CC3)c2c1 Show InChI InChI=1S/C26H28FN3O3/c1-16-23(21-15-19(6-9-22(21)28-16)24(31)26(33)29(2)3)25(32)30-12-10-18(11-13-30)14-17-4-7-20(27)8-5-17/h4-9,15,18,28H,10-14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Scios, Inc Curated by ChEMBL					Assay Description Inhibition of human p38alpha after 60 mins				Bioorg Med Chem Lett 20: 1059-62 (2010) Article DOI: 10.1016/j.bmcl.2009.12.031 BindingDB Entry DOI: 10.7270/Q2J38SP4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315932 ((S)-N-ethyl-3,4-dimethyl-N-(2-(1-phenylethylamino)...) Show SMILES CCN(C(=O)c1ccc(C)c(C)c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H26N4O/c1-5-27(22(28)20-12-11-16(2)17(3)15-20)21-13-14-24-23(26-21)25-18(4)19-9-7-6-8-10-19/h6-15,18H,5H2,1-4H3,(H,24,25,26)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315950 ((S)-N-(4-hydroxybutyl)-N-(2-(1-phenylethylamino)py...) Show SMILES C[C@H](Nc1nccc(n1)N(CCCCO)C(=O)c1ccc2OCCc2c1)c1ccccc1 |r| Show InChI InChI=1S/C25H28N4O3/c1-18(19-7-3-2-4-8-19)27-25-26-13-11-23(28-25)29(14-5-6-15-30)24(31)21-9-10-22-20(17-21)12-16-32-22/h2-4,7-11,13,17-18,30H,5-6,12,14-16H2,1H3,(H,26,27,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50266947 (2-(6-chloro-5-((2R,5S)-4-(4-fluorobenzyl)-2,5-dime...) Show SMILES C[C@H]1CN([C@H](C)CN1Cc1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C |r| Show InChI InChI=1S/C27H30ClFN4O3/c1-16-13-33(17(2)12-32(16)14-18-6-8-19(29)9-7-18)26(35)21-10-20-22(25(34)27(36)30(3)4)15-31(5)24(20)11-23(21)28/h6-11,15-17H,12-14H2,1-5H3/t16-,17+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38beta				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50309528 (2-(6-chloro-5-(4-(4-fluorobenzyl)piperidine-1-carb...) Show SMILES CN(C)C(=O)C(=O)c1nn(C)c2cc(Cl)c(cc12)C(=O)N1CCC(Cc2ccc(F)cc2)CC1 Show InChI InChI=1S/C25H26ClFN4O3/c1-29(2)25(34)23(32)22-19-13-18(20(26)14-21(19)30(3)28-22)24(33)31-10-8-16(9-11-31)12-15-4-6-17(27)7-5-15/h4-7,13-14,16H,8-12H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Scios, Inc Curated by ChEMBL					Assay Description Inhibition of human p38alpha after 60 mins				Bioorg Med Chem Lett 20: 1059-62 (2010) Article DOI: 10.1016/j.bmcl.2009.12.031 BindingDB Entry DOI: 10.7270/Q2J38SP4
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315935 ((S)-3-cyclopropyl-N-ethyl-N-(2-(1-phenylethylamino...) Show SMILES CCN(C(=O)c1cccc(c1)C1CC1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C24H26N4O/c1-3-28(23(29)21-11-7-10-20(16-21)19-12-13-19)22-14-15-25-24(27-22)26-17(2)18-8-5-4-6-9-18/h4-11,14-17,19H,3,12-13H2,1-2H3,(H,25,26,27)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15240 (4-[1-methyl-2-(piperidin-4-yl)-4-[3-(trifluorometh...) Show SMILES C[C@H](Nc1nccc(n1)-c1c(nc(C2CCNCC2)n1C)-c1cccc(c1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C28H29F3N6/c1-18(19-7-4-3-5-8-19)34-27-33-16-13-23(35-27)25-24(21-9-6-10-22(17-21)28(29,30)31)36-26(37(25)2)20-11-14-32-15-12-20/h3-10,13,16-18,20,32H,11-12,14-15H2,1-2H3,(H,33,34,35)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as inhibition of gamma-32p-ATP incorporation into biotin peptide substrate after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2556-9 (2010) Article DOI: 10.1016/j.bmcl.2010.02.088 BindingDB Entry DOI: 10.7270/Q2VT1S84
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315925 ((S)-N-ethyl-1-methyl-N-(2-(1-phenylethylamino)pyri...) Show SMILES CCN(C(=O)c1cn(C)c2ccccc12)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C24H25N5O/c1-4-29(23(30)20-16-28(3)21-13-9-8-12-19(20)21)22-14-15-25-24(27-22)26-17(2)18-10-6-5-7-11-18/h5-17H,4H2,1-3H3,(H,25,26,27)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315942 ((S)-N-(2-(1-phenylethylamino)pyrimidin-4-yl)-N-((t...) Show SMILES C[C@H](Nc1nccc(n1)N(CC1CCOCC1)C(=O)c1ccc2OCCc2c1)c1ccccc1 |r| Show InChI InChI=1S/C27H30N4O3/c1-19(21-5-3-2-4-6-21)29-27-28-13-9-25(30-27)31(18-20-10-14-33-15-11-20)26(32)23-7-8-24-22(17-23)12-16-34-24/h2-9,13,17,19-20H,10-12,14-16,18H2,1H3,(H,28,29,30)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315918 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1ccc2OCOc2c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C22H22N4O3/c1-3-26(21(27)17-9-10-18-19(13-17)29-14-28-18)20-11-12-23-22(25-20)24-15(2)16-7-5-4-6-8-16/h4-13,15H,3,14H2,1-2H3,(H,23,24,25)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315940 ((S)-N-(cyclopropylmethyl)-N-(2-(1-phenylethylamino...) Show SMILES C[C@H](Nc1nccc(n1)N(CC1CC1)C(=O)c1ccc2OCCc2c1)c1ccccc1 |r| Show InChI InChI=1S/C25H26N4O2/c1-17(19-5-3-2-4-6-19)27-25-26-13-11-23(28-25)29(16-18-7-8-18)24(30)21-9-10-22-20(15-21)12-14-31-22/h2-6,9-11,13,15,17-18H,7-8,12,14,16H2,1H3,(H,26,27,28)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315926 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1cc2ccccc2o1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H22N4O2/c1-3-27(22(28)20-15-18-11-7-8-12-19(18)29-20)21-13-14-24-23(26-21)25-16(2)17-9-5-4-6-10-17/h4-16H,3H2,1-2H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315923 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1ccc2CCCCc2c1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C25H28N4O/c1-3-29(24(30)22-14-13-20-11-7-8-12-21(20)17-22)23-15-16-26-25(28-23)27-18(2)19-9-5-4-6-10-19/h4-6,9-10,13-18H,3,7-8,11-12H2,1-2H3,(H,26,27,28)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306495 (2-(6-chloro-5-((2R,5S)-4-(cyano(4-fluorophenyl)met...) Show SMILES C[C@H]1CN([C@H](C)CN1C(C#N)c1ccc(F)cc1)C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C |r| Show InChI InChI=1S/C28H29ClFN5O3/c1-16-14-35(17(2)13-34(16)25(12-31)18-6-8-19(30)9-7-18)27(37)21-10-20-22(26(36)28(38)32(3)4)15-33(5)24(20)11-23(21)29/h6-11,15-17,25H,13-14H2,1-5H3/t16-,17+,25?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315924 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1csc2ccccc12)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C23H22N4OS/c1-3-27(22(28)19-15-29-20-12-8-7-11-18(19)20)21-13-14-24-23(26-21)25-16(2)17-9-5-4-6-10-17/h4-16H,3H2,1-2H3,(H,24,25,26)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315927 ((S)-N-ethyl-N-(2-(1-phenylethylamino)pyrimidin-4-y...) Show SMILES CCN(C(=O)c1ccccc1)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C21H22N4O/c1-3-25(20(26)18-12-8-5-9-13-18)19-14-15-22-21(24-19)23-16(2)17-10-6-4-7-11-17/h4-16H,3H2,1-2H3,(H,22,23,24)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	193	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315928 ((S)-2-chloro-N-ethyl-N-(2-(1-phenylethylamino)pyri...) Show SMILES CCN(C(=O)c1ccccc1Cl)c1ccnc(N[C@@H](C)c2ccccc2)n1 |r| Show InChI InChI=1S/C21H21ClN4O/c1-3-26(20(27)17-11-7-8-12-18(17)22)19-13-14-23-21(25-19)24-15(2)16-9-5-4-6-10-16/h4-15H,3H2,1-2H3,(H,23,24,25)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315961 ((S)-N-(4-aminobutyl)-N-(2-(1-hydroxypropan-2-ylami...) Show SMILES C[C@@H](CO)Nc1nccc(n1)N(CCCCN)C(=O)c1ccc2OCCc2c1 |r| Show InChI InChI=1S/C20H27N5O3/c1-14(13-26)23-20-22-9-6-18(24-20)25(10-3-2-8-21)19(27)16-4-5-17-15(12-16)7-11-28-17/h4-6,9,12,14,26H,2-3,7-8,10-11,13,21H2,1H3,(H,22,23,24)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Scios Inc. Curated by ChEMBL					Assay Description Inhibition of human p38alpha assessed as gamma-[32P]ATP incorporation after 60 mins by scintillation counting				Bioorg Med Chem Lett 20: 2560-3 (2010) Article DOI: 10.1016/j.bmcl.2010.02.090 BindingDB Entry DOI: 10.7270/Q2BV7GS3
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 89 total )  |  Next  |  Last  >>

Jump to: