Compile Data Set for Download or QSAR

Found 273 hits with Last Name = 'mcfarlane' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069352 ((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-5,6,7,8-tetrahyd...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C37H45NO3S/c1-35(2)19-18-28-13-16-30(38-32(28)23-35)15-12-26-8-7-10-29(22-26)33(42-25-37(20-21-37)24-34(39)40)17-14-27-9-5-6-11-31(27)36(3,4)41/h5-13,15-16,22,33,41H,14,17-21,23-25H2,1-4H3,(H,39,40)/b15-12+/t33-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069352 ((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-5,6,7,8-tetrahyd...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C37H45NO3S/c1-35(2)19-18-28-13-16-30(38-32(28)23-35)15-12-26-8-7-10-29(22-26)33(42-25-37(20-21-37)24-34(39)40)17-14-27-9-5-6-11-31(27)36(3,4)41/h5-13,15-16,22,33,41H,14,17-21,23-25H2,1-4H3,(H,39,40)/b15-12+/t33-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069356 ((R)-2-(1-((3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(3...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCCc3n2)c1 Show InChI InChI=1S/C35H41NO3S/c1-34(2,39)30-12-5-3-9-26(30)16-19-32(40-24-35(20-21-35)23-33(37)38)28-11-7-8-25(22-28)14-17-29-18-15-27-10-4-6-13-31(27)36-29/h3,5,7-9,11-12,14-15,17-18,22,32,39H,4,6,10,13,16,19-21,23-24H2,1-2H3,(H,37,38)/b17-14+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286261 ((S)-2-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES CC[C@H](CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C34H36ClNO3S/c1-4-24(33(37)38)22-40-32(19-15-25-9-5-6-11-30(25)34(2,3)39)27-10-7-8-23(20-27)12-17-29-18-14-26-13-16-28(35)21-31(26)36-29/h5-14,16-18,20-21,24,32,39H,4,15,19,22H2,1-3H3,(H,37,38)/b17-12+/t24-,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069375 ((R)-2-(1-((1-(3-(2-(5,7-dihydrothieno[3,4-b]pyridi...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CSCc3n2)c1 Show InChI InChI=1S/C33H37NO3S2/c1-32(2,37)28-9-4-3-7-24(28)12-15-30(39-22-33(16-17-33)19-31(35)36)25-8-5-6-23(18-25)10-13-27-14-11-26-20-38-21-29(26)34-27/h3-11,13-14,18,30,37H,12,15-17,19-22H2,1-2H3,(H,35,36)/b13-10+/t30-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50069356 ((R)-2-(1-((3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(3...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCCc3n2)c1 Show InChI InChI=1S/C35H41NO3S/c1-34(2,39)30-12-5-3-9-26(30)16-19-32(40-24-35(20-21-35)23-33(37)38)28-11-7-8-25(22-28)14-17-29-18-15-27-10-4-6-13-31(27)36-29/h3,5,7-9,11-12,14-15,17-18,22,32,39H,4,6,10,13,16,19-21,23-24H2,1-2H3,(H,37,38)/b17-14+/t32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286260 (4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...) Show SMILES CC(C)(CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)CC(O)=O Show InChI InChI=1S/C35H38ClNO3S/c1-34(2,22-33(38)39)23-41-32(19-15-25-9-5-6-11-30(25)35(3,4)40)27-10-7-8-24(20-27)12-17-29-18-14-26-13-16-28(36)21-31(26)37-29/h5-14,16-18,20-21,32,40H,15,19,22-23H2,1-4H3,(H,38,39)/b17-12+/t32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286257 ((2R,3R)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl...) Show SMILES C[C@@H](S[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)[C@H](C)C(O)=O Show InChI InChI=1S/C34H36ClNO3S/c1-22(33(37)38)23(2)40-32(19-15-25-9-5-6-11-30(25)34(3,4)39)27-10-7-8-24(20-27)12-17-29-18-14-26-13-16-28(35)21-31(26)36-29/h5-14,16-18,20-23,32,39H,15,19H2,1-4H3,(H,37,38)/b17-12+/t22-,23+,32+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286253 ((S)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@@H](CC(O)=O)S[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C33H34ClNO3S/c1-22(19-32(36)37)39-31(18-14-24-8-4-5-10-29(24)33(2,3)38)26-9-6-7-23(20-26)11-16-28-17-13-25-12-15-27(34)21-30(25)35-28/h4-13,15-17,20-22,31,38H,14,18-19H2,1-3H3,(H,36,37)/b16-11+/t22-,31+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069372 ((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)21-28-13-16-29(37-31(28)22-34)15-12-25-8-7-10-27(20-25)32(41-24-36(18-19-36)23-33(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,20,32,40H,14,17-19,21-24H2,1-4H3,(H,38,39)/b15-12+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069350 ((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-6,7-dihydro-5H-[...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCC(C)(C)c3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)19-18-27-13-16-29(37-33(27)34)15-12-25-8-7-10-28(22-25)31(41-24-36(20-21-36)23-32(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,22,31,40H,14,17-21,23-24H2,1-4H3,(H,38,39)/b15-12+/t31-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50285678 ((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...) Show SMILES CC(C)(O)c1ccc(CC[C@@H](SCC2(CC(O)=O)CC2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)cc1 Show InChI InChI=1S/C33H33Cl2NO3S2/c1-32(2,39)24-10-6-21(7-11-24)9-14-26(40-20-33(16-17-33)19-28(37)38)23-5-3-4-22(18-23)8-12-25-13-15-27-30(36-25)29(34)31(35)41-27/h3-8,10-13,15,18,26,39H,9,14,16-17,19-20H2,1-2H3,(H,37,38)/b12-8+/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50069352 ((1-{(R)-1-{3-[(E)-2-(7,7-Dimethyl-5,6,7,8-tetrahyd...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C37H45NO3S/c1-35(2)19-18-28-13-16-30(38-32(28)23-35)15-12-26-8-7-10-29(22-26)33(42-25-37(20-21-37)24-34(39)40)17-14-27-9-5-6-11-31(27)36(3,4)41/h5-13,15-16,22,33,41H,14,17-21,23-25H2,1-4H3,(H,39,40)/b15-12+/t33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50052024 (CHEMBL787 | montelukast) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |r| Show InChI InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069372 ((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)21-28-13-16-29(37-31(28)22-34)15-12-25-8-7-10-27(20-25)32(41-24-36(18-19-36)23-33(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,20,32,40H,14,17-19,21-24H2,1-4H3,(H,38,39)/b15-12+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286262 (4-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...) Show SMILES CC(CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)CC(O)=O Show InChI InChI=1S/C34H36ClNO3S/c1-23(19-33(37)38)22-40-32(18-14-25-8-4-5-10-30(25)34(2,3)39)27-9-6-7-24(20-27)11-16-29-17-13-26-12-15-28(35)21-31(26)36-29/h4-13,15-17,20-21,23,32,39H,14,18-19,22H2,1-3H3,(H,37,38)/b16-11+/t23?,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286255 (3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...) Show SMILES CC(S[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(C)C(O)=O Show InChI InChI=1S/C34H36ClNO3S/c1-22(33(37)38)23(2)40-32(19-15-25-9-5-6-11-30(25)34(3,4)39)27-10-7-8-24(20-27)12-17-29-18-14-26-13-16-28(35)21-31(26)36-29/h5-14,16-18,20-23,32,39H,15,19H2,1-4H3,(H,37,38)/b17-12+/t22?,23?,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009073 (4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50069355 ((1-{(R)-1-{3-[(E)-2-(6,7-Dihydro-5H-[1]pyrindin-2-...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCc3n2)c1 Show InChI InChI=1S/C34H39NO3S/c1-33(2,38)29-11-4-3-8-25(29)15-18-31(39-23-34(19-20-34)22-32(36)37)27-10-5-7-24(21-27)13-16-28-17-14-26-9-6-12-30(26)35-28/h3-5,7-8,10-11,13-14,16-17,21,31,38H,6,9,12,15,18-20,22-23H2,1-2H3,(H,36,37)/b16-13+/t31-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50069373 (2-(1-(((1R)-3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(...) Show SMILES CC1CCCc2ccc(\C=C\c3cccc(c3)[C@@H](CCc3ccccc3C(C)(C)O)SCC3(CC(O)=O)CC3)nc12 Show InChI InChI=1S/C36H43NO3S/c1-25-8-6-11-28-15-18-30(37-34(25)28)17-14-26-9-7-12-29(22-26)32(41-24-36(20-21-36)23-33(38)39)19-16-27-10-4-5-13-31(27)35(2,3)40/h4-5,7,9-10,12-15,17-18,22,25,32,40H,6,8,11,16,19-21,23-24H2,1-3H3,(H,38,39)/b17-14+/t25?,32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50285677 ((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...) Show SMILES OC(=O)CC1(CS[C@H](CCc2cccc(c2)C2(O)CCC2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C34H33Cl2NO3S2/c35-30-31-28(42-32(30)36)13-11-26(37-31)10-8-22-4-1-6-24(18-22)27(41-21-33(16-17-33)20-29(38)39)12-9-23-5-2-7-25(19-23)34(40)14-3-15-34/h1-2,4-8,10-11,13,18-19,27,40H,3,9,12,14-17,20-21H2,(H,38,39)/b10-8+/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50052024 (CHEMBL787 | montelukast) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |r| Show InChI InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069364 ((1-{(R)-1-{3-[(E)-2-(6-Butyl-5-methyl-pyridin-2-yl...) Show SMILES CCCCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C Show InChI InChI=1S/C36H45NO3S/c1-5-6-14-32-26(2)15-18-30(37-32)19-16-27-10-9-12-29(23-27)33(41-25-36(21-22-36)24-34(38)39)20-17-28-11-7-8-13-31(28)35(3,4)40/h7-13,15-16,18-19,23,33,40H,5-6,14,17,20-22,24-25H2,1-4H3,(H,38,39)/b19-16+/t33-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50216211 (CHEMBL143597) Show SMILES CCCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C Show InChI InChI=1S/C35H43NO3S/c1-5-9-31-25(2)14-17-29(36-31)18-15-26-10-8-12-28(22-26)32(40-24-35(20-21-35)23-33(37)38)19-16-27-11-6-7-13-30(27)34(3,4)39/h6-8,10-15,17-18,22,32,39H,5,9,16,19-21,23-24H2,1-4H3,(H,37,38)/b18-15+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069355 ((1-{(R)-1-{3-[(E)-2-(6,7-Dihydro-5H-[1]pyrindin-2-...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCc3n2)c1 Show InChI InChI=1S/C34H39NO3S/c1-33(2,38)29-11-4-3-8-25(29)15-18-31(39-23-34(19-20-34)22-32(36)37)27-10-5-7-24(21-27)13-16-28-17-14-26-9-6-12-30(26)35-28/h3-5,7-8,10-11,13-14,16-17,21,31,38H,6,9,12,15,18-20,22-23H2,1-2H3,(H,36,37)/b16-13+/t31-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069373 (2-(1-(((1R)-3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(...) Show SMILES CC1CCCc2ccc(\C=C\c3cccc(c3)[C@@H](CCc3ccccc3C(C)(C)O)SCC3(CC(O)=O)CC3)nc12 Show InChI InChI=1S/C36H43NO3S/c1-25-8-6-11-28-15-18-30(37-34(25)28)17-14-26-9-7-12-29(22-26)32(41-24-36(20-21-36)23-33(38)39)19-16-27-10-4-5-13-31(27)35(2,3)40/h4-5,7,9-10,12-15,17-18,22,25,32,40H,6,8,11,16,19-21,23-24H2,1-3H3,(H,38,39)/b17-14+/t25?,32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50285683 ((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C33H33Cl2NO3S2/c1-32(2,39)25-9-4-3-7-22(25)11-14-26(40-20-33(16-17-33)19-28(37)38)23-8-5-6-21(18-23)10-12-24-13-15-27-30(36-24)29(34)31(35)41-27/h3-10,12-13,15,18,26,39H,11,14,16-17,19-20H2,1-2H3,(H,37,38)/b12-10+/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50069372 ((1-{(R)-1-{3-[(E)-2-(6,6-Dimethyl-6,7-dihydro-5H-[...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CC(C)(C)Cc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-34(2)21-28-13-16-29(37-31(28)22-34)15-12-25-8-7-10-27(20-25)32(41-24-36(18-19-36)23-33(38)39)17-14-26-9-5-6-11-30(26)35(3,4)40/h5-13,15-16,20,32,40H,14,17-19,21-24H2,1-4H3,(H,38,39)/b15-12+/t32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069357 (CHEMBL141640 | [1-((R)-3-[2-(1-Hydroxy-1-methyl-et...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCCCc3n2)c1 Show InChI InChI=1S/C36H43NO3S/c1-35(2,40)31-13-7-6-10-27(31)17-20-33(41-25-36(21-22-36)24-34(38)39)29-12-8-9-26(23-29)15-18-30-19-16-28-11-4-3-5-14-32(28)37-30/h6-10,12-13,15-16,18-19,23,33,40H,3-5,11,14,17,20-22,24-25H2,1-2H3,(H,38,39)/b18-15+/t33-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286254 (3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...) Show SMILES CCC(CC(O)=O)S[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C34H36ClNO3S/c1-4-29(22-33(37)38)40-32(19-15-24-9-5-6-11-30(24)34(2,3)39)26-10-7-8-23(20-26)12-17-28-18-14-25-13-16-27(35)21-31(25)36-28/h5-14,16-18,20-21,29,32,39H,4,15,19,22H2,1-3H3,(H,37,38)/b17-12+/t29?,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284902 ((1-{(R)-1-{3-[(E)-2-(4-Cyclobutyl-thiazol-2-yl)-vi...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2nc(cs2)C2CCC2)c1 Show InChI InChI=1S/C33H39NO3S2/c1-32(2,37)27-12-4-3-8-24(27)14-15-29(39-22-33(17-18-33)20-31(35)36)26-11-5-7-23(19-26)13-16-30-34-28(21-38-30)25-9-6-10-25/h3-5,7-8,11-13,16,19,21,25,29,37H,6,9-10,14-15,17-18,20,22H2,1-2H3,(H,35,36)/b16-13+/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286256 ((R)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@H](CC(O)=O)S[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C33H34ClNO3S/c1-22(19-32(36)37)39-31(18-14-24-8-4-5-10-29(24)33(2,3)38)26-9-6-7-23(20-26)11-16-28-17-13-25-12-15-27(34)21-30(25)35-28/h4-13,15-17,20-22,31,38H,14,18-19H2,1-3H3,(H,36,37)/b16-11+/t22-,31-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284902 ((1-{(R)-1-{3-[(E)-2-(4-Cyclobutyl-thiazol-2-yl)-vi...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2nc(cs2)C2CCC2)c1 Show InChI InChI=1S/C33H39NO3S2/c1-32(2,37)27-12-4-3-8-24(27)14-15-29(39-22-33(17-18-33)20-31(35)36)26-11-5-7-23(19-26)13-16-30-34-28(21-38-30)25-9-6-10-25/h3-5,7-8,11-13,16,19,21,25,29,37H,6,9-10,14-15,17-18,20,22H2,1-2H3,(H,35,36)/b16-13+/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50069375 ((R)-2-(1-((1-(3-(2-(5,7-dihydrothieno[3,4-b]pyridi...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CSCc3n2)c1 Show InChI InChI=1S/C33H37NO3S2/c1-32(2,37)28-9-4-3-7-24(28)12-15-30(39-22-33(16-17-33)19-31(35)36)25-8-5-6-23(18-25)10-13-27-14-11-26-20-38-21-29(26)34-27/h3-11,13-14,18,30,37H,12,15-17,19-22H2,1-2H3,(H,35,36)/b13-10+/t30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069373 (2-(1-(((1R)-3-(2-(2-hydroxypropan-2-yl)phenyl)-1-(...) Show SMILES CC1CCCc2ccc(\C=C\c3cccc(c3)[C@@H](CCc3ccccc3C(C)(C)O)SCC3(CC(O)=O)CC3)nc12 Show InChI InChI=1S/C36H43NO3S/c1-25-8-6-11-28-15-18-30(37-34(25)28)17-14-26-9-7-12-29(22-26)32(41-24-36(20-21-36)23-33(38)39)19-16-27-10-4-5-13-31(27)35(2,3)40/h4-5,7,9-10,12-15,17-18,22,25,32,40H,6,8,11,16,19-21,23-24H2,1-3H3,(H,38,39)/b17-14+/t25?,32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50052024 (CHEMBL787 | montelukast) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |r| Show InChI InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50285675 ((1-{(R)-1-{3-[(E)-2-(2,3-Dichloro-thieno[3,2-b]pyr...) Show SMILES OC(=O)CC1(CS[C@H](CCc2ccc(cc2)C2(O)CCC2)c2cccc(\C=C\c3ccc4sc(Cl)c(Cl)c4n3)c2)CC1 Show InChI InChI=1S/C34H33Cl2NO3S2/c35-30-31-28(42-32(30)36)14-12-26(37-31)11-7-23-3-1-4-24(19-23)27(41-21-33(17-18-33)20-29(38)39)13-8-22-5-9-25(10-6-22)34(40)15-2-16-34/h1,3-7,9-12,14,19,27,40H,2,8,13,15-18,20-21H2,(H,38,39)/b11-7+/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286259 (3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]...) Show SMILES CC(C)(CC(O)=O)S[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C34H36ClNO3S/c1-33(2,22-32(37)38)40-31(19-15-24-9-5-6-11-29(24)34(3,4)39)26-10-7-8-23(20-26)12-17-28-18-14-25-13-16-27(35)21-30(25)36-28/h5-14,16-18,20-21,31,39H,15,19,22H2,1-4H3,(H,37,38)/b17-12+/t31-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50216211 (CHEMBL143597) Show SMILES CCCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C Show InChI InChI=1S/C35H43NO3S/c1-5-9-31-25(2)14-17-29(36-31)18-15-26-10-8-12-28(22-26)32(40-24-35(20-21-35)23-33(37)38)19-16-27-11-6-7-13-30(27)34(3,4)39/h6-8,10-15,17-18,22,32,39H,5,9,16,19-21,23-24H2,1-4H3,(H,37,38)/b18-15+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284899 (CHEMBL287722 | {1-[(R)-3-[2-(1-Hydroxy-1-methyl-et...) Show SMILES CC(CC(F)(F)F)c1csc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)n1 Show InChI InChI=1S/C33H38F3NO3S2/c1-22(18-33(34,35)36)27-20-41-29(37-27)14-11-23-7-6-9-25(17-23)28(42-21-32(15-16-32)19-30(38)39)13-12-24-8-4-5-10-26(24)31(2,3)40/h4-11,14,17,20,22,28,40H,12-13,15-16,18-19,21H2,1-3H3,(H,38,39)/b14-11+/t22?,28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50284899 (CHEMBL287722 | {1-[(R)-3-[2-(1-Hydroxy-1-methyl-et...) Show SMILES CC(CC(F)(F)F)c1csc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)n1 Show InChI InChI=1S/C33H38F3NO3S2/c1-22(18-33(34,35)36)27-20-41-29(37-27)14-11-23-7-6-9-25(17-23)28(42-21-32(15-16-32)19-30(38)39)13-12-24-8-4-5-10-26(24)31(2,3)40/h4-11,14,17,20,22,28,40H,12-13,15-16,18-19,21H2,1-3H3,(H,38,39)/b14-11+/t22?,28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]-LTD4 binding on guinea-pig lung membranes				Bioorg Med Chem Lett 5: 1615-1620 (1995) Article DOI: 10.1016/0960-894X(95)00265-U BindingDB Entry DOI: 10.7270/Q2NV9J6V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50285671 (CHEMBL86063 | {1-[(R)-1-{3-[(E)-2-(2,3-Dichloro-th...) Show SMILES OCc1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(Cl)c(Cl)c3n2)c1 Show InChI InChI=1S/C31H29Cl2NO3S2/c32-28-29-26(39-30(28)33)13-11-24(34-29)10-8-20-4-3-7-22(16-20)25(38-19-31(14-15-31)17-27(36)37)12-9-21-5-1-2-6-23(21)18-35/h1-8,10-11,13,16,25,35H,9,12,14-15,17-19H2,(H,36,37)/b10-8+/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069354 (CHEMBL141405 | [1-((R)-3-[2-(1-Hydroxy-1-methyl-et...) Show SMILES CC1CCc2ccc(\C=C\c3cccc(c3)[C@@H](CCc3ccccc3C(C)(C)O)SCC3(CC(O)=O)CC3)nc12 Show InChI InChI=1S/C35H41NO3S/c1-24-11-13-27-14-17-29(36-33(24)27)16-12-25-7-6-9-28(21-25)31(40-23-35(19-20-35)22-32(37)38)18-15-26-8-4-5-10-30(26)34(2,3)39/h4-10,12,14,16-17,21,24,31,39H,11,13,15,18-20,22-23H2,1-3H3,(H,37,38)/b16-12+/t24?,31-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069370 ((1-{(R)-1-{3-[(E)-2-(2,3-Dihydro-thieno[3,2-b]pyri...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3SCCc3n2)c1 Show InChI InChI=1S/C33H37NO3S2/c1-32(2,37)27-9-4-3-7-24(27)11-14-29(39-22-33(17-18-33)21-31(35)36)25-8-5-6-23(20-25)10-12-26-13-15-30-28(34-26)16-19-38-30/h3-10,12-13,15,20,29,37H,11,14,16-19,21-22H2,1-2H3,(H,35,36)/b12-10+/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50069371 ((1-{(R)-1-{3-[(E)-2-(8,8-Dimethyl-5,6,7,8-tetrahyd...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3CCCC(C)(C)c3n2)c1 Show InChI InChI=1S/C37H45NO3S/c1-35(2)20-8-12-28-15-18-30(38-34(28)35)17-14-26-9-7-11-29(23-26)32(42-25-37(21-22-37)24-33(39)40)19-16-27-10-5-6-13-31(27)36(3,4)41/h5-7,9-11,13-15,17-18,23,32,41H,8,12,16,19-22,24-25H2,1-4H3,(H,39,40)/b17-14+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to LTD4 receptor of guinea pig lung membrane with human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50285674 ((1-{(R)-1-{3-[(E)-2-(2,3-Difluoro-thieno[3,2-b]pyr...) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3sc(F)c(F)c3n2)c1 Show InChI InChI=1S/C33H33F2NO3S2/c1-32(2,39)25-9-4-3-7-22(25)11-14-26(40-20-33(16-17-33)19-28(37)38)23-8-5-6-21(18-23)10-12-24-13-15-27-30(36-24)29(34)31(35)41-27/h3-10,12-13,15,18,26,39H,11,14,16-17,19-20H2,1-2H3,(H,37,38)/b12-10+/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of binding of [ H]-LTD4 to DMSO differentiated U937 cell membranes				Bioorg Med Chem Lett 5: 2551-2556 (1995) Article DOI: 10.1016/0960-894X(95)00448-3 BindingDB Entry DOI: 10.7270/Q2W37W8Q
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50052024 (CHEMBL787 | montelukast) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |r| Show InChI InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of DMSO differentiated human U937 cell membranes				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50286253 ((S)-3-{(R)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@@H](CC(O)=O)S[C@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C33H34ClNO3S/c1-22(19-32(36)37)39-31(18-14-24-8-4-5-10-29(24)33(2,3)38)26-9-6-7-23(20-26)11-16-28-17-13-25-12-15-27(34)21-30(25)35-28/h4-13,15-17,20-22,31,38H,14,18-19H2,1-3H3,(H,36,37)/b16-11+/t22-,31+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required for inhibition of binding of [3H]-LTD4 to guinea pig lung membranes(different expt)				Bioorg Med Chem Lett 5: 283-288 (1995) Article DOI: 10.1016/0960-894X(95)00023-M BindingDB Entry DOI: 10.7270/Q2KD1XW7
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50216210 (CHEMBL141234) Show SMILES CCc1nc(\C=C\c2cccc(c2)[C@@H](CCc2ccccc2C(C)(C)O)SCC2(CC(O)=O)CC2)ccc1C Show InChI InChI=1S/C34H41NO3S/c1-5-30-24(2)13-16-28(35-30)17-14-25-9-8-11-27(21-25)31(39-23-34(19-20-34)22-32(36)37)18-15-26-10-6-7-12-29(26)33(3,4)38/h6-14,16-17,21,31,38H,5,15,18-20,22-23H2,1-4H3,(H,36,37)/b17-14+/t31-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50216361 (CHEMBL143326) Show SMILES CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC(O)=O)CC1)c1cccc(\C=C\c2cccc(n2)C2CCC2)c1 Show InChI InChI=1S/C35H41NO3S/c1-34(2,39)30-14-4-3-9-26(30)17-19-32(40-24-35(20-21-35)23-33(37)38)28-12-5-8-25(22-28)16-18-29-13-7-15-31(36-29)27-10-6-11-27/h3-5,7-9,12-16,18,22,27,32,39H,6,10-11,17,19-21,23-24H2,1-2H3,(H,37,38)/b18-16+/t32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]-LTD4 binding to LTD4 receptor of guinea pig lung membrane without human serum albumin (HSA).				Bioorg Med Chem Lett 8: 453-8 (1999) BindingDB Entry DOI: 10.7270/Q2M907SH
					More data for this Ligand-Target Pair

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