Compile Data Set for Download or QSAR

Found 149 hits with Last Name = 'mcglinchey' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398759 (CHEMBL2179655) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC\C=C\c1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H31ClN2O3/c1-38-16-15-34-30-24-11-14-28(39)32(30)41-33(34)31-25(18-26(21-37-31)23-9-12-27(36)13-10-23)20-35(34,29(38)19-24)40-17-5-8-22-6-3-2-4-7-22/h2-14,18,21,29,33,39H,15-17,19-20H2,1H3/b8-5+/t29-,33+,34+,35-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342116 ((S)-(1,3,4-oxadiazol-2-yl)(6-phenoxy-1,2,3,4-tetra...) Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1nnco1 |r| Show InChI InChI=1S/C19H16N2O3/c22-18(19-21-20-12-23-19)15-7-6-14-11-17(9-8-13(14)10-15)24-16-4-2-1-3-5-16/h1-5,8-9,11-12,15H,6-7,10H2/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398758 (CHEMBL2179656) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OCCCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H33ClN2O3/c1-38-16-15-34-30-24-11-14-28(39)32(30)41-33(34)31-25(18-26(21-37-31)23-9-12-27(36)13-10-23)20-35(34,29(38)19-24)40-17-5-8-22-6-3-2-4-7-22/h2-4,6-7,9-14,18,21,29,33,39H,5,8,15-17,19-20H2,1H3/t29-,33+,34+,35-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398760 (CHEMBL2179652) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OCCCc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H37ClN2O3/c39-30-13-10-26(11-14-30)29-19-28-21-38(43-18-4-7-24-5-2-1-3-6-24)32-20-27-12-15-31(42)35-33(27)37(38,36(44-35)34(28)40-22-29)16-17-41(32)23-25-8-9-25/h1-3,5-6,10-15,19,22,25,32,36,42H,4,7-9,16-18,20-21,23H2/t32-,36+,37+,38-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398750 (CHEMBL2179662) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC(=O)CCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H31ClN2O4/c1-38-16-15-34-30-23-10-13-27(39)32(30)41-33(34)31-24(17-25(20-37-31)22-8-11-26(36)12-9-22)19-35(34,28(38)18-23)42-29(40)14-7-21-5-3-2-4-6-21/h2-6,8-13,17,20,28,33,39H,7,14-16,18-19H2,1H3/t28-,33+,34+,35-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398750 (CHEMBL2179662) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC(=O)CCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H31ClN2O4/c1-38-16-15-34-30-23-10-13-27(39)32(30)41-33(34)31-24(17-25(20-37-31)22-8-11-26(36)12-9-22)19-35(34,28(38)18-23)42-29(40)14-7-21-5-3-2-4-6-21/h2-6,8-13,17,20,28,33,39H,7,14-16,18-19H2,1H3/t28-,33+,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398751 (CHEMBL2179661) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC(=O)Cc1ccccc1)ccc5O |r| Show InChI InChI=1S/C34H29ClN2O4/c1-37-14-13-33-29-22-9-12-26(38)31(29)40-32(33)30-23(16-24(19-36-30)21-7-10-25(35)11-8-21)18-34(33,27(37)17-22)41-28(39)15-20-5-3-2-4-6-20/h2-12,16,19,27,32,38H,13-15,17-18H2,1H3/t27-,32+,33+,34-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398758 (CHEMBL2179656) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OCCCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H33ClN2O3/c1-38-16-15-34-30-24-11-14-28(39)32(30)41-33(34)31-25(18-26(21-37-31)23-9-12-27(36)13-10-23)20-35(34,29(38)19-24)40-17-5-8-22-6-3-2-4-7-22/h2-4,6-7,9-14,18,21,29,33,39H,5,8,15-17,19-20H2,1H3/t29-,33+,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342118 ((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...) Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1nnc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C24H19N3O3/c28-22(24-27-26-23(30-24)21-8-4-5-13-25-21)18-10-9-17-15-20(12-11-16(17)14-18)29-19-6-2-1-3-7-19/h1-8,11-13,15,18H,9-10,14H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398753 (CHEMBL2179658) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)Cc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C37H33ClN2O4/c38-28-11-8-24(9-12-28)27-17-26-19-37(44-31(42)16-22-4-2-1-3-5-22)30-18-25-10-13-29(41)34-32(25)36(37,35(43-34)33(26)39-20-27)14-15-40(30)21-23-6-7-23/h1-5,8-13,17,20,23,30,35,41H,6-7,14-16,18-19,21H2/t30-,35+,36+,37-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398759 (CHEMBL2179655) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC\C=C\c1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H31ClN2O3/c1-38-16-15-34-30-24-11-14-28(39)32(30)41-33(34)31-25(18-26(21-37-31)23-9-12-27(36)13-10-23)20-35(34,29(38)19-24)40-17-5-8-22-6-3-2-4-7-22/h2-14,18,21,29,33,39H,15-17,19-20H2,1H3/b8-5+/t29-,33+,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398760 (CHEMBL2179652) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OCCCc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H37ClN2O3/c39-30-13-10-26(11-14-30)29-19-28-21-38(43-18-4-7-24-5-2-1-3-6-24)32-20-27-12-15-31(42)35-33(27)37(38,36(44-35)34(28)40-22-29)16-17-41(32)23-25-8-9-25/h1-3,5-6,10-15,19,22,25,32,36,42H,4,7-9,16-18,20-21,23H2/t32-,36+,37+,38-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398753 (CHEMBL2179658) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)Cc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C37H33ClN2O4/c38-28-11-8-24(9-12-28)27-17-26-19-37(44-31(42)16-22-4-2-1-3-5-22)30-18-25-10-13-29(41)34-32(25)36(37,35(43-34)33(26)39-20-27)14-15-40(30)21-23-6-7-23/h1-5,8-13,17,20,23,30,35,41H,6-7,14-16,18-19,21H2/t30-,35+,36+,37-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342064 ((S)-2-(6-phenoxy-1,2,3,4-tetrahydronaphthalene-2-c...) Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)C#N |r| Show InChI InChI=1S/C21H16N2O3/c22-12-19-13-23-21(26-19)20(24)16-7-6-15-11-18(9-8-14(15)10-16)25-17-4-2-1-3-5-17/h1-5,8-9,11,13,16H,6-7,10H2/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342123 ((R)-(1,3,4-oxadiazol-2-yl)(6-phenoxy-1,2,3,4-tetra...) Show SMILES O=C([C@@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1nnco1 |r| Show InChI InChI=1S/C19H16N2O3/c22-18(19-21-20-12-23-19)15-7-6-14-11-17(9-8-13(14)10-15)24-16-4-2-1-3-5-16/h1-5,8-9,11-12,15H,6-7,10H2/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398751 (CHEMBL2179661) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC(=O)Cc1ccccc1)ccc5O |r| Show InChI InChI=1S/C34H29ClN2O4/c1-37-14-13-33-29-22-9-12-26(38)31(29)40-32(33)30-23(16-24(19-36-30)21-7-10-25(35)11-8-21)18-34(33,27(37)17-22)41-28(39)15-20-5-3-2-4-6-20/h2-12,16,19,27,32,38H,13-15,17-18H2,1H3/t27-,32+,33+,34-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342104 ((S)-(5-(benzyloxy)-2,3-dihydro-1H-inden-2-yl)(5-(p...) Show SMILES O=C([C@H]1Cc2ccc(OCc3ccccc3)cc2C1)c1ncc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C25H20N2O3/c28-24(25-27-15-23(30-25)22-8-4-5-11-26-22)20-12-18-9-10-21(14-19(18)13-20)29-16-17-6-2-1-3-7-17/h1-11,14-15,20H,12-13,16H2/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398758 (CHEMBL2179656) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OCCCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H33ClN2O3/c1-38-16-15-34-30-24-11-14-28(39)32(30)41-33(34)31-25(18-26(21-37-31)23-9-12-27(36)13-10-23)20-35(34,29(38)19-24)40-17-5-8-22-6-3-2-4-7-22/h2-4,6-7,9-14,18,21,29,33,39H,5,8,15-17,19-20H2,1H3/t29-,33+,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342117 ((S)-methyl 5-(6-phenoxy-1,2,3,4-tetrahydronaphthal...) Show SMILES COC(=O)c1nnc(o1)C(=O)[C@H]1CCc2cc(Oc3ccccc3)ccc2C1 |r| Show InChI InChI=1S/C21H18N2O5/c1-26-21(25)20-23-22-19(28-20)18(24)15-8-7-14-12-17(10-9-13(14)11-15)27-16-5-3-2-4-6-16/h2-6,9-10,12,15H,7-8,11H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398759 (CHEMBL2179655) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC\C=C\c1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H31ClN2O3/c1-38-16-15-34-30-24-11-14-28(39)32(30)41-33(34)31-25(18-26(21-37-31)23-9-12-27(36)13-10-23)20-35(34,29(38)19-24)40-17-5-8-22-6-3-2-4-7-22/h2-14,18,21,29,33,39H,15-17,19-20H2,1H3/b8-5+/t29-,33+,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398755 (CHEMBL2179653) Show SMILES CO[C@]12Cc3cc(cnc3[C@@H]3Oc4c5c(C[C@H]1N(C)CC[C@@]235)ccc4O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H25ClN2O3/c1-30-10-9-26-22-16-5-8-20(31)24(22)33-25(26)23-17(13-27(26,32-2)21(30)12-16)11-18(14-29-23)15-3-6-19(28)7-4-15/h3-8,11,14,21,25,31H,9-10,12-13H2,1-2H3/t21-,25+,26+,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342124 ((R)-methyl 5-(6-phenoxy-1,2,3,4-tetrahydronaphthal...) Show SMILES COC(=O)c1nnc(o1)C(=O)[C@@H]1CCc2cc(Oc3ccccc3)ccc2C1 |r| Show InChI InChI=1S/C21H18N2O5/c1-26-21(25)20-23-22-19(28-20)18(24)15-8-7-14-12-17(10-9-13(14)11-15)27-16-5-3-2-4-6-16/h2-6,9-10,12,15H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398760 (CHEMBL2179652) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OCCCc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H37ClN2O3/c39-30-13-10-26(11-14-30)29-19-28-21-38(43-18-4-7-24-5-2-1-3-6-24)32-20-27-12-15-31(42)35-33(27)37(38,36(44-35)34(28)40-22-29)16-17-41(32)23-25-8-9-25/h1-3,5-6,10-15,19,22,25,32,36,42H,4,7-9,16-18,20-21,23H2/t32-,36+,37+,38-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398754 (CHEMBL2179654) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C33H29ClN2O3/c1-36-14-13-32-28-22-9-12-26(37)30(28)39-31(32)29-23(15-24(18-35-29)21-7-10-25(34)11-8-21)17-33(32,27(36)16-22)38-19-20-5-3-2-4-6-20/h2-12,15,18,27,31,37H,13-14,16-17,19H2,1H3/t27-,31+,32+,33-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398756 (CHEMBL2179650) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OCc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C36H33ClN2O3/c37-28-11-8-24(9-12-28)27-16-26-18-36(41-21-23-4-2-1-3-5-23)30-17-25-10-13-29(40)33-31(25)35(36,34(42-33)32(26)38-19-27)14-15-39(30)20-22-6-7-22/h1-5,8-13,16,19,22,30,34,40H,6-7,14-15,17-18,20-21H2/t30-,34+,35+,36-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342096 ((S)-(5-phenyl-2,3-dihydro-1H-inden-2-yl)(5-(pyridi...) Show SMILES O=C([C@H]1Cc2ccc(cc2C1)-c1ccccc1)c1ncc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C24H18N2O2/c27-23(24-26-15-22(28-24)21-8-4-5-11-25-21)20-13-18-10-9-17(12-19(18)14-20)16-6-2-1-3-7-16/h1-12,15,20H,13-14H2/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398765 (CHEMBL2179649) Show SMILES CO[C@]12Cc3cc(cnc3[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H29ClN2O3/c1-35-30-14-20-12-21(18-4-7-22(31)8-5-18)15-32-26(20)28-29(30)10-11-33(16-17-2-3-17)24(30)13-19-6-9-23(34)27(36-28)25(19)29/h4-9,12,15,17,24,28,34H,2-3,10-11,13-14,16H2,1H3/t24-,28+,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342100 ((S)-(5-phenoxy-2,3-dihydro-1H-inden-2-yl)(5-(pyrid...) Show SMILES O=C([C@H]1Cc2ccc(Oc3ccccc3)cc2C1)c1ncc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C24H18N2O3/c27-23(24-26-15-22(29-24)21-8-4-5-11-25-21)18-12-16-9-10-20(14-17(16)13-18)28-19-6-2-1-3-7-19/h1-11,14-15,18H,12-13H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342062 ((S)-oxazol-2-yl(6-phenoxy-1,2,3,4-tetrahydronaphth...) Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1ncco1 |r| Show InChI InChI=1S/C20H17NO3/c22-19(20-21-10-11-23-20)16-7-6-15-13-18(9-8-14(15)12-16)24-17-4-2-1-3-5-17/h1-5,8-11,13,16H,6-7,12H2/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342066 ((S)-methyl 6-(2-(6-phenoxy-1,2,3,4-tetrahydronapht...) Show SMILES COC(=O)c1cccc(n1)-c1cnc(o1)C(=O)[C@H]1CCc2cc(Oc3ccccc3)ccc2C1 |r| Show InChI InChI=1S/C27H22N2O5/c1-32-27(31)23-9-5-8-22(29-23)24-16-28-26(34-24)25(30)19-11-10-18-15-21(13-12-17(18)14-19)33-20-6-3-2-4-7-20/h2-9,12-13,15-16,19H,10-11,14H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50080467 (5'-(Chlorophenyl)-17-(cyclopropylmethyl) -6,7-dide...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45C(Oc1c24)c1ncc(cc1C[C@@]35O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C29H27ClN2O3/c30-21-6-3-17(4-7-21)20-11-19-13-29(34)23-12-18-5-8-22(33)26-24(18)28(29,27(35-26)25(19)31-14-20)9-10-32(23)15-16-1-2-16/h3-8,11,14,16,23,27,33-34H,1-2,9-10,12-13,15H2/t23-,27?,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor by radioligand binding assay				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398752 (CHEMBL2179659) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)CCc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H35ClN2O4/c39-29-12-9-25(10-13-29)28-18-27-20-38(45-32(43)15-8-23-4-2-1-3-5-23)31-19-26-11-14-30(42)35-33(26)37(38,36(44-35)34(27)40-21-28)16-17-41(31)22-24-6-7-24/h1-5,9-14,18,21,24,31,36,42H,6-8,15-17,19-20,22H2/t31-,36+,37+,38-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398762 (CHEMBL2179663) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C=C35)-c1ccc(Cl)cc1 |r,t:30| Show InChI InChI=1S/C29H25ClN2O2/c30-21-6-3-17(4-7-21)20-11-19-12-22-23-13-18-5-8-24(33)27-25(18)29(22,28(34-27)26(19)31-14-20)9-10-32(23)15-16-1-2-16/h3-8,11-12,14,16,23,28,33H,1-2,9-10,13,15H2/t23-,28+,29+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342069 ((S)-methyl 2-(6-(benzyloxy)-1,2,3,4-tetrahydronaph...) Show SMILES COC(=O)c1cnc(o1)C(=O)[C@H]1CCc2cc(OCc3ccccc3)ccc2C1 |r| Show InChI InChI=1S/C23H21NO5/c1-27-23(26)20-13-24-22(29-20)21(25)18-8-7-17-12-19(10-9-16(17)11-18)28-14-15-5-3-2-4-6-15/h2-6,9-10,12-13,18H,7-8,11,14H2,1H3/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398764 (CHEMBL2179651) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC\C=C\c1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H35ClN2O3/c39-30-13-10-26(11-14-30)29-19-28-21-38(43-18-4-7-24-5-2-1-3-6-24)32-20-27-12-15-31(42)35-33(27)37(38,36(44-35)34(28)40-22-29)16-17-41(32)23-25-8-9-25/h1-7,10-15,19,22,25,32,36,42H,8-9,16-18,20-21,23H2/b7-4+/t32-,36+,37+,38-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398753 (CHEMBL2179658) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)Cc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C37H33ClN2O4/c38-28-11-8-24(9-12-28)27-17-26-19-37(44-31(42)16-22-4-2-1-3-5-22)30-18-25-10-13-29(41)34-32(25)36(37,35(43-34)33(26)39-20-27)14-15-40(30)21-23-6-7-23/h1-5,8-13,17,20,23,30,35,41H,6-7,14-16,18-19,21H2/t30-,35+,36+,37-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342070 ((S)-2-(6-(benzyloxy)-1,2,3,4-tetrahydronaphthalene...) Show SMILES O=C([C@H]1CCc2cc(OCc3ccccc3)ccc2C1)c1ncc(o1)C#N |r| Show InChI InChI=1S/C22H18N2O3/c23-12-20-13-24-22(27-20)21(25)18-7-6-17-11-19(9-8-16(17)10-18)26-14-15-4-2-1-3-5-15/h1-5,8-9,11,13,18H,6-7,10,14H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342071 ((S)-(6-(benzyloxy)-1,2,3,4-tetrahydronaphthalen-2-...) Show SMILES O=C([C@H]1CCc2cc(OCc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C26H22N2O3/c29-25(26-28-16-24(31-26)23-8-4-5-13-27-23)21-10-9-20-15-22(12-11-19(20)14-21)30-17-18-6-2-1-3-7-18/h1-8,11-13,15-16,21H,9-10,14,17H2/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398764 (CHEMBL2179651) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC\C=C\c1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H35ClN2O3/c39-30-13-10-26(11-14-30)29-19-28-21-38(43-18-4-7-24-5-2-1-3-6-24)32-20-27-12-15-31(42)35-33(27)37(38,36(44-35)34(28)40-22-29)16-17-41(32)23-25-8-9-25/h1-7,10-15,19,22,25,32,36,42H,8-9,16-18,20-21,23H2/b7-4+/t32-,36+,37+,38-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342058 ((S)-2-(6-phenyl-1,2,3,4-tetrahydronaphthalene-2-ca...) Show SMILES O=C([C@H]1CCc2cc(ccc2C1)-c1ccccc1)c1ncc(o1)C#N |r| Show InChI InChI=1S/C21H16N2O2/c22-12-19-13-23-21(25-19)20(24)18-9-8-16-10-15(6-7-17(16)11-18)14-4-2-1-3-5-14/h1-7,10,13,18H,8-9,11H2/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398764 (CHEMBL2179651) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC\C=C\c1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H35ClN2O3/c39-30-13-10-26(11-14-30)29-19-28-21-38(43-18-4-7-24-5-2-1-3-6-24)32-20-27-12-15-31(42)35-33(27)37(38,36(44-35)34(28)40-22-29)16-17-41(32)23-25-8-9-25/h1-7,10-15,19,22,25,32,36,42H,8-9,16-18,20-21,23H2/b7-4+/t32-,36+,37+,38-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398761 (CHEMBL611438) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1cc(cnc41)-c1ccc(Cl)cc1)ccc5O |r| Show InChI InChI=1S/C26H23ClN2O3/c1-29-9-8-25-21-15-4-7-19(30)23(21)32-24(25)22-16(12-26(25,31)20(29)11-15)10-17(13-28-22)14-2-5-18(27)6-3-14/h2-7,10,13,20,24,30-31H,8-9,11-12H2,1H3/t20-,24+,25+,26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor by radioligand binding assay				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50398752 (CHEMBL2179659) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)CCc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C38H35ClN2O4/c39-29-12-9-25(10-13-29)28-18-27-20-38(45-32(43)15-8-23-4-2-1-3-5-23)31-19-26-11-14-30(42)35-33(26)37(38,36(44-35)34(27)40-21-28)16-17-41(31)22-24-6-7-24/h1-5,9-14,18,21,24,31,36,42H,6-8,15-17,19-20,22H2/t31-,36+,37+,38-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342093 ((S)-(6-(benzyloxy)-1,2,3,4-tetrahydronaphthalen-2-...) Show SMILES Ic1cnc(o1)C(=O)[C@H]1CCc2cc(OCc3ccccc3)ccc2C1 |r| Show InChI InChI=1S/C21H18INO3/c22-19-12-23-21(26-19)20(24)17-7-6-16-11-18(9-8-15(16)10-17)25-13-14-4-2-1-3-5-14/h1-5,8-9,11-12,17H,6-7,10,13H2/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398750 (CHEMBL2179662) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OC(=O)CCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C35H31ClN2O4/c1-38-16-15-34-30-23-10-13-27(39)32(30)41-33(34)31-24(17-25(20-37-31)22-8-11-26(36)12-9-22)19-35(34,28(38)18-23)42-29(40)14-7-21-5-3-2-4-6-21/h2-6,8-13,17,20,28,33,39H,7,14-16,18-19H2,1H3/t28-,33+,34+,35-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50342065 ((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...) Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C25H20N2O3/c28-24(25-27-16-23(30-25)22-8-4-5-13-26-22)19-10-9-18-15-21(12-11-17(18)14-19)29-20-6-2-1-3-7-20/h1-8,11-13,15-16,19H,9-10,14H2/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50342065 ((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...) Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C25H20N2O3/c28-24(25-27-16-23(30-25)22-8-4-5-13-26-22)19-10-9-18-15-21(12-11-17(18)14-19)29-20-6-2-1-3-7-20/h1-8,11-13,15-16,19H,9-10,14H2/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion				J Med Chem 54: 2805-22 (2011) Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50398754 (CHEMBL2179654) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OCc1ccccc1)ccc5O |r| Show InChI InChI=1S/C33H29ClN2O3/c1-36-14-13-32-28-22-9-12-26(37)30(28)39-31(32)29-23(15-24(18-35-29)21-7-10-25(34)11-8-21)17-33(32,27(36)16-22)38-19-20-5-3-2-4-6-20/h2-12,15,18,27,31,37H,13-14,16-17,19H2,1H3/t27-,31+,32+,33-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398756 (CHEMBL2179650) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OCc1ccccc1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C36H33ClN2O3/c37-28-11-8-24(9-12-28)27-16-26-18-36(41-21-23-4-2-1-3-5-23)30-17-25-10-13-29(40)33-31(25)35(36,34(42-33)32(26)38-19-27)14-15-39(30)20-22-6-7-22/h1-5,8-13,16,19,22,30,34,40H,6-7,14-15,17-18,20-21H2/t30-,34+,35+,36-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50398765 (CHEMBL2179649) Show SMILES CO[C@]12Cc3cc(cnc3[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4O)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H29ClN2O3/c1-35-30-14-20-12-21(18-4-7-22(31)8-5-18)15-32-26(20)28-29(30)10-11-33(16-17-2-3-17)24(30)13-19-6-9-23(34)27(36-28)25(19)29/h4-9,12,15,17,24,28,34H,2-3,10-11,13-14,16H2,1H3/t24-,28+,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysis				J Med Chem 55: 8350-63 (2012) Article DOI: 10.1021/jm300686p BindingDB Entry DOI: 10.7270/Q2N87BX5
					More data for this Ligand-Target Pair

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