Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mineralocorticoid receptor (Homo sapiens (Human)) | BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Mineralocorticoid receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mineralocorticoid receptor (Homo sapiens (Human)) | BDBM50226465 (CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Mineralocorticoid receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50226465 (CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 201 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Progesterone receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 224 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Progesterone receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50226465 (CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 224 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Glucorticoid receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM50226465 (CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Androgen receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 252 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Glucorticoid receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Androgen receptor (Homo sapiens (Human)) | BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 315 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Androgen receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat)) | BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat)) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Farnesoid X receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile acid receptor (Homo sapiens (Human)) | BDBM50226465 (CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Farnesoid X receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM50207814 ((2S,1'R,2'S)-2-(2'-phosphonocyclopropyl)glycine | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM50207811 ((2S,1'R,2'S,3'R)-2-(2'-phosphono-3'-phenylcyclopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat)) | BDBM50207814 ((2S,1'R,2'S)-2-(2'-phosphonocyclopropyl)glycine | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat)) | BDBM50207811 ((2S,1'R,2'S,3'R)-2-(2'-phosphono-3'-phenylcyclopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat)) | BDBM50207812 ((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM50207812 ((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM50207813 ((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat)) | BDBM50207810 ((2S,1'S,2'R,3'R)-2-(2'-phosphono-3'-phenylcyclopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assay | Bioorg Med Chem 15: 3161-70 (2007) Article DOI: 10.1016/j.bmc.2007.02.040 BindingDB Entry DOI: 10.7270/Q2CN74RR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 1 group I member 2 (Homo sapiens (Human)) | BDBM21725 ((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Pregnane X receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nuclear receptor subfamily 1 group I member 2 (Homo sapiens (Human)) | BDBM50226465 (CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Perugia Curated by ChEMBL | Assay Description Inhibitory concentration against Pregnane X receptor | J Med Chem 48: 6948-55 (2005) Article DOI: 10.1021/jm0505056 BindingDB Entry DOI: 10.7270/Q20V8DKV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50231755 (6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443088 (CHEMBL3087216) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438277 (CHEMBL2408412) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443089 (CHEMBL3086715) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443089 (CHEMBL3086715) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438295 (CHEMBL2408568) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443090 (CHEMBL3086712) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438289 (CHEMBL2408574) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443091 (CHEMBL3087511) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443092 (CHEMBL3085792) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443093 (CHEMBL3087217) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443087 (CHEMBL3087214) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443086 (CHEMBL3087508) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438278 (CHEMBL2408411) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443084 (CHEMBL3087220) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443085 (AFQ056 | Mavoglurant) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443083 (CHEMBL3087219) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438294 (CHEMBL2408569) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438298 (CHEMBL2408565) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443082 (CHEMBL3087513) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443081 (CHEMBL3087212) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443080 (CHEMBL3087514) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443080 (CHEMBL3087514) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438288 (CHEMBL2408575) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438305 (CHEMBL2408585) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50438291 (CHEMBL2408572) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation... | Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8 | |||||||||||
More data for this Ligand-Target Pair |
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