Compile Data Set for Download or QSAR

Found 559 hits with Last Name = 'nicoll-griffith' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human DP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human TP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human DP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human DP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human DP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human DP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human TP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50205278 (2-(4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfonyl)-...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CCC(CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human DP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50205277 ((S)-2-(4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfon...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human DP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human TP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP2 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP2 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP2 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP2 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human IP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP2 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP3 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	745	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Activity at CRTH2 receptor				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	892	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP3 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50205277 ((S)-2-(4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfon...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human TP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP1 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human TP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP3 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP1 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	6.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human IP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human TP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP1 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	9.99E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human FP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50205274 (CHEMBL426387 | [(3R)-5-bromo-4-(4-chlorobenzyl)-7-...) Show SMILES OC(=O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21 Show InChI InChI=1S/C20H16BrClFNO2/c21-17-9-14(23)8-16-15-6-3-12(7-18(25)26)19(15)24(20(16)17)10-11-1-4-13(22)5-2-11/h1-2,4-5,8-9,12H,3,6-7,10H2,(H,25,26)/t12-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human FP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human IP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP3 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human IP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human IP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human FP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human FP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP3 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human FP receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50184217 (2-((R)-4-(4-chlorobenzyl)-5-(1-hydroxyethyl)-7-(me...) Show SMILES CC(O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O Show InChI InChI=1S/C23H24ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,13,15,26H,5,8-9,12H2,1-2H3,(H,27,28)/t13?,15-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP1 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50205276 (CHEMBL385126 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CC(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C22H19ClFNO3/c1-12(26)18-9-16(24)10-19-17-7-4-14(8-20(27)28)21(17)25(22(18)19)11-13-2-5-15(23)6-3-13/h2-3,5-6,9-10,14H,4,7-8,11H2,1H3,(H,27,28)/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP4 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50184212 ((R)-2-(4-(4-chlorobenzyl)-5-acetyl-7-(methylsulfon...) Show SMILES CC(=O)c1cc(cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12)S(C)(=O)=O |r| Show InChI InChI=1S/C23H22ClNO5S/c1-13(26)19-10-17(31(2,29)30)11-20-18-8-5-15(9-21(27)28)22(18)25(23(19)20)12-14-3-6-16(24)7-4-14/h3-4,6-7,10-11,15H,5,8-9,12H2,1-2H3,(H,27,28)/t15-/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Binding affinity to human EP1 receptor expressed in HEK293 cells				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50174030 ((E)-6-isopropyl-8-(3-(2-(3-methyl-1,2,4-oxadiazol-...) Show SMILES CC(C)c1cc(-c2cccc(\C=C(\c3nc(C)no3)c3ccc(cc3)S(C)(=O)=O)c2)c2ncccc2c1 Show InChI InChI=1S/C30H27N3O3S/c1-19(2)25-17-24-9-6-14-31-29(24)27(18-25)23-8-5-7-21(15-23)16-28(30-32-20(3)33-36-30)22-10-12-26(13-11-22)37(4,34)35/h5-19H,1-4H3/b28-16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against PDE4B				Bioorg Med Chem Lett 15: 5241-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor (Homo sapiens (Human))	BDBM50205275 (CHEMBL426559 | [(3R)-4-(4-chlorobenzyl)-7-fluoro-5...) Show SMILES CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulation				J Med Chem 50: 794-806 (2007) Article DOI: 10.1021/jm0603668 BindingDB Entry DOI: 10.7270/Q20P0ZP2
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50331776 ((S)-4,4-dichloro-N-((S)-1-cyano-2-phenylethyl)-2-(...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)[C@H](N[C@@H](CC(Cl)Cl)C(=O)N[C@@H](Cc1ccccc1)C#N)C(F)(F)F |r| Show InChI InChI=1S/C28H26Cl2F3N3O3S/c1-40(38,39)23-13-11-20(12-14-23)19-7-9-21(10-8-19)26(28(31,32)33)36-24(16-25(29)30)27(37)35-22(17-34)15-18-5-3-2-4-6-18/h2-14,22,24-26,36H,15-16H2,1H3,(H,35,37)/t22-,24-,26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of trypanosoma cruzi Cruzipain				Bioorg Med Chem Lett 20: 7444-9 (2010) Article DOI: 10.1016/j.bmcl.2010.10.015 BindingDB Entry DOI: 10.7270/Q29S1R8D
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50174030 ((E)-6-isopropyl-8-(3-(2-(3-methyl-1,2,4-oxadiazol-...) Show SMILES CC(C)c1cc(-c2cccc(\C=C(\c3nc(C)no3)c3ccc(cc3)S(C)(=O)=O)c2)c2ncccc2c1 Show InChI InChI=1S/C30H27N3O3S/c1-19(2)25-17-24-9-6-14-31-29(24)27(18-25)23-8-5-7-21(15-23)16-28(30-32-20(3)33-36-30)22-10-12-26(13-11-22)37(4,34)35/h5-19H,1-4H3/b28-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against PDE4A				Bioorg Med Chem Lett 15: 5241-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50174025 (6-isopropyl-8-(3-(2-(4-(methylsulfonyl)phenyl)-2-(...) Show SMILES CC(C)c1cc(-c2cccc(\C=C(\c3nccs3)c3ccc(cc3)S(C)(=O)=O)c2)c2ncccc2c1 Show InChI InChI=1S/C30H26N2O2S2/c1-20(2)25-18-24-8-5-13-31-29(24)27(19-25)23-7-4-6-21(16-23)17-28(30-32-14-15-35-30)22-9-11-26(12-10-22)36(3,33)34/h4-20H,1-3H3/b28-17+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibitory activity against PDE4D				Bioorg Med Chem Lett 15: 5241-6 (2005) Article DOI: 10.1016/j.bmcl.2005.08.036 BindingDB Entry DOI: 10.7270/Q2B56KHG
					More data for this Ligand-Target Pair
Cathepsin K (Homo sapiens (Human))	BDBM50233032 ((S)-4,4-difluoro-2-[(S)-2,2,2-trifluoro-1-(4'-meth...) Show SMILES CC(F)(F)C[C@H](N[C@@H](c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F)C(=O)NC(C#N)(C1CC1)C1CC1 Show InChI InChI=1S/C28H30F5N3O3S/c1-26(29,30)15-23(25(37)36-27(16-34,20-9-10-20)21-11-12-21)35-24(28(31,32)33)19-5-3-17(4-6-19)18-7-13-22(14-8-18)40(2,38)39/h3-8,13-14,20-21,23-24,35H,9-12,15H2,1-2H3,(H,36,37)/t23-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of humanized rabbit cathepsin K				Bioorg Med Chem Lett 18: 923-8 (2008) Article DOI: 10.1016/j.bmcl.2007.12.047 BindingDB Entry DOI: 10.7270/Q21J9BM2
					More data for this Ligand-Target Pair

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