Compile Data Set for Download or QSAR

Found 42 hits with Last Name = 'phillips' and Initial = 'tb'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250852 (CHEMBL4078217) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(Cc2ccccc2)n1)C(F)(F)F Show InChI InChI=1S/C17H15F6N3O2/c18-16(19,20)14(17(21,22)23)28-15(27)25-9-12(10-25)13-6-7-26(24-13)8-11-4-2-1-3-5-11/h1-7,12,14H,8-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250848 (CHEMBL4059676) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C16H13F6N3O2/c17-15(18,19)13(16(20,21)22)27-14(26)24-8-10(9-24)12-6-7-25(23-12)11-4-2-1-3-5-11/h1-7,10,13H,8-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250859 (CHEMBL4097203) Show SMILES Fc1ccc(cc1F)-n1ccc(n1)C1CN(C1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H11F8N3O2/c17-10-2-1-9(5-11(10)18)27-4-3-12(25-27)8-6-26(7-8)14(28)29-13(15(19,20)21)16(22,23)24/h1-5,8,13H,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250855 (CHEMBL4077745) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1cc(-c2ccccc2)n(n1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C22H17F6N3O2/c23-21(24,25)19(22(26,27)28)33-20(32)30-12-15(13-30)17-11-18(14-7-3-1-4-8-14)31(29-17)16-9-5-2-6-10-16/h1-11,15,19H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250850 (CHEMBL4089505) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1nc(no1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C15H11F6N3O3/c16-14(17,18)12(15(19,20)21)26-13(25)24-6-9(7-24)11-22-10(23-27-11)8-4-2-1-3-5-8/h1-5,9,12H,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250852 (CHEMBL4078217) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(Cc2ccccc2)n1)C(F)(F)F Show InChI InChI=1S/C17H15F6N3O2/c18-16(19,20)14(17(21,22)23)28-15(27)25-9-12(10-25)13-6-7-26(24-13)8-11-4-2-1-3-5-11/h1-7,12,14H,8-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250855 (CHEMBL4077745) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1cc(-c2ccccc2)n(n1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C22H17F6N3O2/c23-21(24,25)19(22(26,27)28)33-20(32)30-12-15(13-30)17-11-18(14-7-3-1-4-8-14)31(29-17)16-9-5-2-6-10-16/h1-11,15,19H,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250859 (CHEMBL4097203) Show SMILES Fc1ccc(cc1F)-n1ccc(n1)C1CN(C1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H11F8N3O2/c17-10-2-1-9(5-11(10)18)27-4-3-12(25-27)8-6-26(7-8)14(28)29-13(15(19,20)21)16(22,23)24/h1-5,8,13H,6-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250854 (CHEMBL4079190) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)-c1cnccn1)C(F)(F)F Show InChI InChI=1S/C14H11F6N5O2/c15-13(16,17)11(14(18,19)20)27-12(26)24-6-8(7-24)9-1-4-25(23-9)10-5-21-2-3-22-10/h1-5,8,11H,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250854 (CHEMBL4079190) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)-c1cnccn1)C(F)(F)F Show InChI InChI=1S/C14H11F6N5O2/c15-13(16,17)11(14(18,19)20)27-12(26)24-6-8(7-24)9-1-4-25(23-9)10-5-21-2-3-22-10/h1-5,8,11H,6-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086083 (1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](CC=C)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C39H47NO11/c1-7-11-29(27-22-34(47-4)37(49-6)35(23-27)48-5)38(43)40-19-9-8-14-30(40)39(44)51-31(26-12-10-13-28(21-26)50-24-36(41)42)17-15-25-16-18-32(45-2)33(20-25)46-3/h7,10,12-13,16,18,20-23,29-31H,1,8-9,11,14-15,17,19,24H2,2-6H3,(H,41,42)/t29-,30-,31?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086090 (1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...) Show SMILES CC[C@H](C(=O)N1CCCC[C@H]1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(OCC(O)=O)c1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C38H47NO11/c1-7-28(26-21-33(46-4)36(48-6)34(22-26)47-5)37(42)39-18-9-8-13-29(39)38(43)50-30(25-11-10-12-27(20-25)49-23-35(40)41)16-14-24-15-17-31(44-2)32(19-24)45-3/h10-12,15,17,19-22,28-30H,7-9,13-14,16,18,23H2,1-6H3,(H,40,41)/t28-,29-,30?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250849 (CHEMBL4068332) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccnc(n1)N1CCOCC1)C(F)(F)F Show InChI InChI=1S/C15H16F6N4O3/c16-14(17,18)11(15(19,20)21)28-13(26)25-7-9(8-25)10-1-2-22-12(23-10)24-3-5-27-6-4-24/h1-2,9,11H,3-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250853 (CHEMBL4102496) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)C1CCOCC1)C(F)(F)F Show InChI InChI=1S/C15H17F6N3O3/c16-14(17,18)12(15(19,20)21)27-13(25)23-7-9(8-23)11-1-4-24(22-11)10-2-5-26-6-3-10/h1,4,9-10,12H,2-3,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250851 (CHEMBL4096459) Show SMILES FC(F)(F)C(OC(=O)N1CCC(CC1)c1ccn(n1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C18H17F6N3O2/c19-17(20,21)15(18(22,23)24)29-16(28)26-9-6-12(7-10-26)14-8-11-27(25-14)13-4-2-1-3-5-13/h1-5,8,11-12,15H,6-7,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250858 (CHEMBL4078417) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)-c1ccc(cc1)C#C)C(F)(F)F Show InChI InChI=1S/C18H13F6N3O2/c1-2-11-3-5-13(6-4-11)27-8-7-14(25-27)12-9-26(10-12)16(28)29-15(17(19,20)21)18(22,23)24/h1,3-8,12,15H,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250857 (CHEMBL4081625) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)N1CCN(CC1)c1ncccn1)C(F)(F)F Show InChI InChI=1S/C15H17F6N5O2/c16-14(17,18)11(15(19,20)21)28-13(27)26-8-10(9-26)24-4-6-25(7-5-24)12-22-2-1-3-23-12/h1-3,10-11H,4-9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086094 (1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...) Show SMILES CCC[C@H](C(=O)N1CCCC[C@H]1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(OCC(O)=O)c1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C39H49NO11/c1-7-11-29(27-22-34(47-4)37(49-6)35(23-27)48-5)38(43)40-19-9-8-14-30(40)39(44)51-31(26-12-10-13-28(21-26)50-24-36(41)42)17-15-25-16-18-32(45-2)33(20-25)46-3/h10,12-13,16,18,20-23,29-31H,7-9,11,14-15,17,19,24H2,1-6H3,(H,41,42)/t29-,30-,31?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086077 (1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](CC2CC2)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C40H49NO11/c1-46-33-17-15-26(20-34(33)47-2)14-16-32(27-9-8-10-29(21-27)51-24-37(42)43)52-40(45)31-11-6-7-18-41(31)39(44)30(19-25-12-13-25)28-22-35(48-3)38(50-5)36(23-28)49-4/h8-10,15,17,20-23,25,30-32H,6-7,11-14,16,18-19,24H2,1-5H3,(H,42,43)/t30-,31-,32?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086092 (1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C(C)C)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C39H49NO11/c1-24(2)36(27-21-33(47-5)37(49-7)34(22-27)48-6)38(43)40-18-9-8-13-29(40)39(44)51-30(26-11-10-12-28(20-26)50-23-35(41)42)16-14-25-15-17-31(45-3)32(19-25)46-4/h10-12,15,17,19-22,24,29-30,36H,8-9,13-14,16,18,23H2,1-7H3,(H,41,42)/t29-,30?,36-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250853 (CHEMBL4102496) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)C1CCOCC1)C(F)(F)F Show InChI InChI=1S/C15H17F6N3O3/c16-14(17,18)12(15(19,20)21)27-13(25)23-7-9(8-23)11-1-4-24(22-11)10-2-5-26-6-3-10/h1,4,9-10,12H,2-3,5-8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086078 (1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@H](C2CCCCC2)c2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C39H47NO8/c1-45-34-22-20-27(24-35(34)46-2)19-21-33(30-16-11-17-31(25-30)47-26-36(41)42)48-39(44)32-18-9-10-23-40(32)38(43)37(28-12-5-3-6-13-28)29-14-7-4-8-15-29/h3,5-6,11-13,16-17,20,22,24-25,29,32-33,37H,4,7-10,14-15,18-19,21,23,26H2,1-2H3,(H,41,42)/t32-,33?,37-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086087 (1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@H](C(C)C)c2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C36H43NO8/c1-24(2)34(26-11-6-5-7-12-26)35(40)37-20-9-8-15-29(37)36(41)45-30(27-13-10-14-28(22-27)44-23-33(38)39)18-16-25-17-19-31(42-3)32(21-25)43-4/h5-7,10-14,17,19,21-22,24,29-30,34H,8-9,15-16,18,20,23H2,1-4H3,(H,38,39)/t29-,30?,34+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086082 (1-[2-(3,4,5-Trimethoxy-phenyl)-pent-4-enoyl]-piper...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@H](CC=C)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C39H47NO11/c1-7-11-29(27-22-34(47-4)37(49-6)35(23-27)48-5)38(43)40-19-9-8-14-30(40)39(44)51-31(26-12-10-13-28(21-26)50-24-36(41)42)17-15-25-16-18-32(45-2)33(20-25)46-3/h7,10,12-13,16,18,20-23,29-31H,1,8-9,11,14-15,17,19,24H2,2-6H3,(H,41,42)/t29-,30+,31?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250856 (CHEMBL4104911) Show SMILES Cn1ccc(n1)C1CN(C1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C11H11F6N3O2/c1-19-3-2-7(18-19)6-4-20(5-6)9(21)22-8(10(12,13)14)11(15,16)17/h2-3,6,8H,4-5H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50250856 (CHEMBL4104911) Show SMILES Cn1ccc(n1)C1CN(C1)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C11H11F6N3O2/c1-19-3-2-7(18-19)6-4-20(5-6)9(21)22-8(10(12,13)14)11(15,16)17/h2-3,6,8H,4-5H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086085 (1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...) Show SMILES CC[C@H](C(=O)N1CCCC[C@H]1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(OCC(O)=O)c1)c1ccccc1 Show InChI InChI=1S/C35H41NO8/c1-4-28(25-11-6-5-7-12-25)34(39)36-20-9-8-15-29(36)35(40)44-30(26-13-10-14-27(22-26)43-23-33(37)38)18-16-24-17-19-31(41-2)32(21-24)42-3/h5-7,10-14,17,19,21-22,28-30H,4,8-9,15-16,18,20,23H2,1-3H3,(H,37,38)/t28?,29-,30?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086075 (1-[2-(3,4,5-Trimethoxy-phenyl)-pentanoyl]-piperidi...) Show SMILES CCC[C@@H](C(=O)N1CCCC[C@H]1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(OCC(O)=O)c1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C39H49NO11/c1-7-11-29(27-22-34(47-4)37(49-6)35(23-27)48-5)38(43)40-19-9-8-14-30(40)39(44)51-31(26-12-10-13-28(21-26)50-24-36(41)42)17-15-25-16-18-32(45-2)33(20-25)46-3/h10,12-13,16,18,20-23,29-31H,7-9,11,14-15,17,19,24H2,1-6H3,(H,41,42)/t29-,30+,31?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086086 (1-[3-Methyl-2-(3,4,5-trimethoxy-phenyl)-butyryl]-p...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@H](C(C)C)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C39H49NO11/c1-24(2)36(27-21-33(47-5)37(49-7)34(22-27)48-6)38(43)40-18-9-8-13-29(40)39(44)51-30(26-11-10-12-28(20-26)50-23-35(41)42)16-14-25-15-17-31(45-3)32(19-25)46-4/h10-12,15,17,19-22,24,29-30,36H,8-9,13-14,16,18,23H2,1-7H3,(H,41,42)/t29-,30?,36+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086079 (1-(2-Cyclohexyl-2-phenyl-acetyl)-piperidine-2-carb...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C2CCCCC2)c2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C39H47NO8/c1-45-34-22-20-27(24-35(34)46-2)19-21-33(30-16-11-17-31(25-30)47-26-36(41)42)48-39(44)32-18-9-10-23-40(32)38(43)37(28-12-5-3-6-13-28)29-14-7-4-8-15-29/h3,5-6,11-13,16-17,20,22,24-25,29,32-33,37H,4,7-10,14-15,18-19,21,23,26H2,1-2H3,(H,41,42)/t32-,33?,37+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086080 (1-(2-Phenyl-propionyl)-piperidine-2-carboxylic aci...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C)c2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C34H39NO8/c1-23(25-10-5-4-6-11-25)33(38)35-19-8-7-14-28(35)34(39)43-29(26-12-9-13-27(21-26)42-22-32(36)37)17-15-24-16-18-30(40-2)31(20-24)41-3/h4-6,9-13,16,18,20-21,23,28-29H,7-8,14-15,17,19,22H2,1-3H3,(H,36,37)/t23-,28-,29?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086089 (1-[3-Cyclopropyl-2-(3,4,5-trimethoxy-phenyl)-propi...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@H](CC2CC2)c2cc(OC)c(OC)c(OC)c2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C40H49NO11/c1-46-33-17-15-26(20-34(33)47-2)14-16-32(27-9-8-10-29(21-27)51-24-37(42)43)52-40(45)31-11-6-7-18-41(31)39(44)30(19-25-12-13-25)28-22-35(48-3)38(50-5)36(23-28)49-4/h8-10,15,17,20-23,25,30-32H,6-7,11-14,16,18-19,24H2,1-5H3,(H,42,43)/t30-,31+,32?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086084 (1-(2-Phenyl-butyryl)-piperidine-2-carboxylic acid ...) Show SMILES CC[C@@H](C(=O)N1CCCC[C@H]1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(OCC(O)=O)c1)c1ccccc1 Show InChI InChI=1S/C35H41NO8/c1-4-28(25-11-6-5-7-12-25)34(39)36-20-9-8-15-29(36)35(40)44-30(26-13-10-14-27(22-26)43-23-33(37)38)18-16-24-17-19-31(41-2)32(21-24)42-3/h5-7,10-14,17,19,21-22,28-30H,4,8-9,15-16,18,20,23H2,1-3H3,(H,37,38)/t28-,29+,30?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086081 (1-(3-Methyl-2-phenyl-butyryl)-piperidine-2-carboxy...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](C(C)C)c2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C36H43NO8/c1-24(2)34(26-11-6-5-7-12-26)35(40)37-20-9-8-15-29(37)36(41)45-30(27-13-10-14-28(22-27)44-23-33(38)39)18-16-25-17-19-31(42-3)32(21-25)43-4/h5-7,10-14,17,19,21-22,24,29-30,34H,8-9,15-16,18,20,23H2,1-4H3,(H,38,39)/t29-,30?,34-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086093 (1-[2-(3,4,5-Trimethoxy-phenyl)-butyryl]-piperidine...) Show SMILES CC[C@@H](C(=O)N1CCCC[C@H]1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1cccc(OCC(O)=O)c1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C38H47NO11/c1-7-28(26-21-33(46-4)36(48-6)34(22-26)47-5)37(42)39-18-9-8-13-29(39)38(43)50-30(25-11-10-12-27(20-25)49-23-35(40)41)16-14-24-15-17-31(44-2)32(19-24)45-3/h10-12,15,17,19-22,28-30H,7-9,13-14,16,18,23H2,1-6H3,(H,40,41)/t28-,29+,30?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250848 (CHEMBL4059676) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccn(n1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C16H13F6N3O2/c17-15(18,19)13(16(20,21)22)27-14(26)24-8-10(9-24)12-6-7-25(23-12)11-4-2-1-3-5-11/h1-7,10,13H,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086076 (1-Diphenylacetyl-piperidine-2-carboxylic acid 1-(3...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)C(c2ccccc2)c2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C39H41NO8/c1-45-34-22-20-27(24-35(34)46-2)19-21-33(30-16-11-17-31(25-30)47-26-36(41)42)48-39(44)32-18-9-10-23-40(32)38(43)37(28-12-5-3-6-13-28)29-14-7-4-8-15-29/h3-8,11-17,20,22,24-25,32-33,37H,9-10,18-19,21,23,26H2,1-2H3,(H,41,42)/t32-,33?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	273	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250850 (CHEMBL4089505) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1nc(no1)-c1ccccc1)C(F)(F)F Show InChI InChI=1S/C15H11F6N3O3/c16-14(17,18)12(15(19,20)21)26-13(25)24-6-9(7-24)11-22-10(23-27-11)8-4-2-1-3-5-8/h1-5,9,12H,6-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50086091 (1-(2-Phenyl-propionyl)-piperidine-2-carboxylic aci...) Show SMILES COc1ccc(CCC(OC(=O)[C@@H]2CCCCN2C(=O)[C@H](C)c2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C34H39NO8/c1-23(25-10-5-4-6-11-25)33(38)35-19-8-7-14-28(35)34(39)43-29(26-12-9-13-27(21-26)42-22-32(36)37)17-15-24-16-18-30(40-2)31(20-24)41-3/h4-6,9-13,16,18,20-21,23,28-29H,7-8,14-15,17,19,22H2,1-3H3,(H,36,37)/t23-,28+,29?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50132547 (1-Phenylacetyl-piperidine-2-carboxylic acid 1-(3-c...) Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2C(=O)Cc2ccccc2)c2cccc(OCC(O)=O)c2)cc1OC Show InChI InChI=1S/C33H37NO8/c1-39-29-17-15-24(19-30(29)40-2)14-16-28(25-11-8-12-26(21-25)41-22-32(36)37)42-33(38)27-13-6-7-18-34(27)31(35)20-23-9-4-3-5-10-23/h3-5,8-12,15,17,19,21,27-28H,6-7,13-14,16,18,20,22H2,1-2H3,(H,36,37)/t27-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Gene Therapeutics Curated by ChEMBL					Assay Description Binding affinity for Mutant F36V-FK506 binding protein by competitive assay based on fluorescence polarization.				J Med Chem 43: 1135-42 (2000) BindingDB Entry DOI: 10.7270/Q2057F45
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250857 (CHEMBL4081625) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)N1CCN(CC1)c1ncccn1)C(F)(F)F Show InChI InChI=1S/C15H17F6N5O2/c16-14(17,18)11(15(19,20)21)28-13(27)26-8-10(9-26)24-4-6-25(7-5-24)12-22-2-1-3-23-12/h1-3,10-11H,4-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50250849 (CHEMBL4068332) Show SMILES FC(F)(F)C(OC(=O)N1CC(C1)c1ccnc(n1)N1CCOCC1)C(F)(F)F Show InChI InChI=1S/C15H16F6N4O3/c16-14(17,18)11(15(19,20)21)28-13(26)25-7-9(8-25)10-1-2-22-12(23-10)24-3-5-27-6-4-24/h1-2,9,11H,3-8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi...				J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG
					More data for this Ligand-Target Pair