Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19202 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.800 | n/a | 1 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19202 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19207 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | 4.40 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19208 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | 8.60 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19224 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19224 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | 6 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19199 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19199 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90 | n/a | 14.4 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19204 (2-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4aH...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | 3 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19225 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10 | n/a | 5 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19231 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | 3 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19201 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | 2.20 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19210 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.80 | n/a | 3.20 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50165103 ((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19226 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10 | n/a | 10 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19211 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.40 | n/a | 11.4 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19232 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.90 | n/a | 5 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19206 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.90 | n/a | 9.30 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19209 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.20 | n/a | 13.9 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19210 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19229 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | 48 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19223 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19223 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10 | n/a | 18 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19217 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10 | n/a | 1 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19192 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19192 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30 | n/a | 9.70 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19192 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.20 | n/a | 9.70 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19213 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19230 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.40 | n/a | 33 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19198 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.70 | n/a | 10.2 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50165105 ((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19193 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.20 | n/a | 2.70 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50165106 ((R)-(5-Chloro-thiophen-2-yl)-[(4aR,5S)-1-(4-fluoro...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19197 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.90 | n/a | 31.3 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19218 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | 21 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19191 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.40 | n/a | 2.90 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19203 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.80 | n/a | 14.3 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19196 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | 1.90 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50165102 ((S)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19195 (4-[(R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.5 | n/a | 19.5 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50165100 ((R)-(2,5-Dichloro-thiophen-3-yl)-[(4aR,5S)-1-(4-fl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19200 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10.4 | n/a | 16.5 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19216 ((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | 6 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50312718 (CHEMBL479527 | torcetrapib) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of CETP-mediated BODIPY-labeled cholesteryl ester transfer after 45 mins by FRET analysis | ACS Med Chem Lett 2: 424-427 (2011) Article DOI: 10.1021/ml100309n BindingDB Entry DOI: 10.7270/Q2125T47 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50165104 ((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 13.8 | n/a | 4.5 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 13.8 | n/a | 4.5 | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 13.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human glucocorticoid receptor alpha by displacement of [3H]-dexamethasone | Bioorg Med Chem Lett 15: 2163-7 (2005) Article DOI: 10.1016/j.bmcl.2005.02.009 BindingDB Entry DOI: 10.7270/Q2WM1CXX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19212 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 16.6 | n/a | 24.2 | n/a | n/a | n/a | n/a |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | J Med Chem 47: 2441-52 (2004) Article DOI: 10.1021/jm030585i BindingDB Entry DOI: 10.7270/Q28W3BKZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM19215 ((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17.4 | n/a | n/a | n/a | n/a | 7.5 | 4 |
Merck Research Laboratories | Assay Description The IC50s were determined by incubating the receptors with radiolabeled dexamethasone in the presence of full log scale concentrations (10-11 M to 10... | Bioorg Med Chem Lett 17: 3354-61 (2007) Article DOI: 10.1016/j.bmcl.2007.03.103 BindingDB Entry DOI: 10.7270/Q2542KVJ | |||||||||||
More data for this Ligand-Target Pair |
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