BindingDB PrimarySearch

Found 125 hits with Last Name = 'ramesha' and Initial = 'c'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151775 (3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-2-me...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM13531 (4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151760 (3-(4-Fluoro-phenoxy)-6-methanesulfonyl-2-methyl-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151758 (3-(2-Chloro-benzyl)-6-methanesulfonyl-2-methyl-1H-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151763 (3-(4-Fluoro-benzyl)-6-methanesulfonyl-2-methyl-1H-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151765 (3-(2,4-Difluoro-phenoxy)-6-methanesulfonyl-2-methy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151762 (3-(2,4-Dichloro-phenoxy)-6-methanesulfonyl-2-methy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151768 (3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15744 (1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151759 (6-Methanesulfonyl-3-(4-methoxy-phenoxy)-2-methyl-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151773 (4-Methanesulfonyl-3-(4-methoxy-phenoxy)-2-methyl-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15749 (1-[2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151766 (3-(4-Chloro-benzyl)-6-methanesulfonyl-2-methyl-1H-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151782 (3-(2,4-Difluoro-benzyl)-6-methanesulfonyl-2-methyl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151783 (6-Methanesulfonyl-3-(4-methoxy-benzyl)-2-methyl-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151767 (3-(4-Chloro-phenoxy)-6-methanesulfonyl-2-methyl-1H...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15743 (1-(2,4-difluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151770 (3-(2-Chloro-4-methoxy-phenylsulfanyl)-6-methanesul...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15745 (1-(2,4-difluorophenyl)-4-{[3-(pyridin-3-yloxy)phen...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151776 (3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151776 (3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151784 (CHEMBL184022 \| [3-(4-Fluoro-phenylsulfanyl)-6-meth...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151774 (6-Methanesulfonyl-3-(4-methoxy-phenylsulfanyl)-2-m...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151768 (3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15750 (4-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151779 ((4-Fluoro-phenyl)-(6-methanesulfonyl-2-methyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15754 ((2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151772 (3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15740 (1-(4-fluorophenyl)-4-{[3-(pyridin-3-yl)phenyl]carb...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15748 (1-(4-fluorophenyl)-4-{[3-(2-methanesulfonylethyl)p...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151777 (3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15746 (2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151764 (3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15741 (1-(4-fluorophenyl)-4-{[4-(pyridin-3-yl)phenyl]carb...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151771 (3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15718 ((5-Amino-1-O-tolyl-1H-pyrazol-4-yl)phenylmethanone...) Show SMILES Cc1ccccc1-n1ncc(C(=O)c2ccccc2)c1N Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151778 ((6-Methanesulfonyl-2-methyl-1H-indol-3-yl)-(4-meth...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151770 (3-(2-Chloro-4-methoxy-phenylsulfanyl)-6-methanesul...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15720 (4-benzoyl-1-(4-fluorophenyl)-1H-pyrazol-5-amine \| ...) Show SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151777 (3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15753 ((2R)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151780 (3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-i...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Prostaglandin G/H synthase 2 enzyme activity				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15747 (2-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151764 (3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15725 (1-(4-fluorophenyl)-4-({3-[2-(morpholin-4-yl)ethoxy...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	7.4	30
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15742 (1-(4-fluorophenyl)-4-{[3-(pyridin-4-yl)phenyl]carb...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15734 (1-(4-fluorophenyl)-4-({3-[3-(piperidin-1-yl)prop-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151773 (4-Methanesulfonyl-3-(4-methoxy-phenoxy)-2-methyl-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50151759 (6-Methanesulfonyl-3-(4-methoxy-phenoxy)-2-methyl-1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Inhibitory concentration against human whole blood Prostaglandin G/H synthase 2 enzyme activity was determined				Bioorg Med Chem Lett 14: 4741-5 (2004) Article DOI: 10.1016/j.bmcl.2004.06.075 BindingDB Entry DOI: 10.7270/Q228072S
Roche Palo Alto Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM15728 (1-(4-fluorophenyl)-4-({3-[2-(4-methylpiperazin-1-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto LLC					Assay Description Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...				J Med Chem 49: 1562-75 (2006) Article DOI: 10.1021/jm050736c BindingDB Entry DOI: 10.7270/Q23776ZN
Roche Palo Alto LLC					More data for this Ligand-Target Pair

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