Compile Data Set for Download or QSAR

Found 236 hits with Last Name = 'sacaan' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50297306 (CHEMBL540982 | {2-[3-(4-Fluoro-benzyl)-benzo[b]thi...) Show SMILES CN(C)CCc1sc2ccccc2c1Cc1ccc(F)cc1 Show InChI InChI=1S/C19H20FNS/c1-21(2)12-11-19-17(13-14-7-9-15(20)10-8-14)16-5-3-4-6-18(16)22-19/h3-10H,11-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50297304 (CHEMBL560741 | {2-[3-(4-Fluoro-benzyl)-1H-inden-2-...) Show SMILES CN(C)CCC1=C(Cc2ccc(F)cc2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C20H22FN/c1-22(2)12-11-17-14-16-5-3-4-6-19(16)20(17)13-15-7-9-18(21)10-8-15/h3-10H,11-14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50297310 ((-)-Dimethyl-{2-[3-((R)-1-pyridin-2-yl-ethyl)-benz...) Show SMILES C[C@H](c1c(CCN(C)C)oc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2O/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297307 (CHEMBL564226 | R-dimethindene) Show SMILES C[C@H](C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |r,c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297304 (CHEMBL560741 | {2-[3-(4-Fluoro-benzyl)-1H-inden-2-...) Show SMILES CN(C)CCC1=C(Cc2ccc(F)cc2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C20H22FN/c1-22(2)12-11-17-14-16-5-3-4-6-19(16)20(17)13-15-7-9-18(21)10-8-15/h3-10H,11-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50297305 (CHEMBL559251 | Dimethyl-[2-(3-pyrazin-2ylmethyl-1H...) Show SMILES CN(C)CCC1=C(Cc2cnccn2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C18H21N3/c1-21(2)10-7-15-11-14-5-3-4-6-17(14)18(15)12-16-13-19-8-9-20-16/h3-6,8-9,13H,7,10-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in HEK293 Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50315205 ((R)-2-(6-fluoro-3-(1-(3-methoxypyrazin-2-yl)ethyl)...) Show SMILES COc1nccnc1[C@H](C)C1=C(CCN(C)C)Cc2cc(F)ccc12 |r,c:11| Show InChI InChI=1S/C20H24FN3O/c1-13(19-20(25-4)23-9-8-22-19)18-14(7-10-24(2)3)11-15-12-16(21)5-6-17(15)18/h5-6,8-9,12-13H,7,10-11H2,1-4H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of histamine H1 receptor				Bioorg Med Chem Lett 20: 5874-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.117 BindingDB Entry DOI: 10.7270/Q26W9BDC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50314264 ((-)-(R)-2-(1-(2-(2-(azetidin-1-yl)ethyl)benzo[b]th...) Show SMILES C[C@H](c1c(CCN2CCC2)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C20H22N2S/c1-15(17-8-4-5-11-21-17)20-16-7-2-3-9-18(16)23-19(20)10-14-22-12-6-13-22/h2-5,7-9,11,15H,6,10,12-14H2,1H3/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in HEK cells assessed as blockade of potassium tail current by standard patch clamp analysis				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297310 ((-)-Dimethyl-{2-[3-((R)-1-pyridin-2-yl-ethyl)-benz...) Show SMILES C[C@H](c1c(CCN(C)C)oc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2O/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297308 ((-)-Dimethyl-{2-[3-((R)-1-pyrazin-2-yl-ethyl)-1H-i...) Show SMILES C[C@H](C1=C(CCN(C)C)Cc2ccccc12)c1cnccn1 |r,c:2| Show InChI InChI=1S/C19H23N3/c1-14(18-13-20-9-10-21-18)19-16(8-11-22(2)3)12-15-6-4-5-7-17(15)19/h4-7,9-10,13-14H,8,11-12H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297308 ((-)-Dimethyl-{2-[3-((R)-1-pyrazin-2-yl-ethyl)-1H-i...) Show SMILES C[C@H](C1=C(CCN(C)C)Cc2ccccc12)c1cnccn1 |r,c:2| Show InChI InChI=1S/C19H23N3/c1-14(18-13-20-9-10-21-18)19-16(8-11-22(2)3)12-15-6-4-5-7-17(15)19/h4-7,9-10,13-14H,8,11-12H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of histamine H1 receptor				Bioorg Med Chem Lett 20: 5874-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.117 BindingDB Entry DOI: 10.7270/Q26W9BDC
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314275 ((-)-(R)-2-(3-(1-(2-fluoropyridin-3-yl)ethyl)benzo[...) Show SMILES C[C@@H](c1c(CCN(C)C)sc2ccccc12)c1cccnc1F |r| Show InChI InChI=1S/C19H21FN2S/c1-13(14-8-6-11-21-19(14)20)18-15-7-4-5-9-16(15)23-17(18)10-12-22(2)3/h4-9,11,13H,10,12H2,1-3H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50315200 (2-(6-fluoro-3-(pyridazin-3-ylmethyl)-1H-inden-2-yl...) Show SMILES CN(C)CCC1=C(Cc2cccnn2)c2ccc(F)cc2C1 |c:5| Show InChI InChI=1S/C18H20FN3/c1-22(2)9-7-13-10-14-11-15(19)5-6-17(14)18(13)12-16-4-3-8-20-21-16/h3-6,8,11H,7,9-10,12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of histamine H1 receptor				Bioorg Med Chem Lett 20: 5874-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.117 BindingDB Entry DOI: 10.7270/Q26W9BDC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50297306 (CHEMBL540982 | {2-[3-(4-Fluoro-benzyl)-benzo[b]thi...) Show SMILES CN(C)CCc1sc2ccccc2c1Cc1ccc(F)cc1 Show InChI InChI=1S/C19H20FNS/c1-21(2)12-11-19-17(13-14-7-9-15(20)10-8-14)16-5-3-4-6-18(16)22-19/h3-10H,11-13H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50297307 (CHEMBL564226 | R-dimethindene) Show SMILES C[C@H](C1=C(CCN(C)C)Cc2ccccc12)c1ccccn1 |r,c:2| Show InChI InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314282 ((-)-(R)-2-(3-(1-(3-fluoropyridin-2-yl)ethyl)benzo[...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ncccc1F |r| Show InChI InChI=1S/C19H21FN2S/c1-13(19-15(20)8-6-11-21-19)18-14-7-4-5-9-16(14)23-17(18)10-12-22(2)3/h4-9,11,13H,10,12H2,1-3H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50315203 ((R)-2-(3-(1-(3-methoxypyrazin-2-yl)ethyl)-6-methyl...) Show SMILES COc1nccnc1[C@H](C)C1=C(CCN(C)C)Cc2cc(C)ccc12 |r,c:11| Show InChI InChI=1S/C21H27N3O/c1-14-6-7-18-17(12-14)13-16(8-11-24(3)4)19(18)15(2)20-21(25-5)23-10-9-22-20/h6-7,9-10,12,15H,8,11,13H2,1-5H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of histamine H1 receptor				Bioorg Med Chem Lett 20: 5874-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.117 BindingDB Entry DOI: 10.7270/Q26W9BDC
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314276 ((-)-(S)-2-(3-(1-(2-chloropyridin-3-yl)ethyl)benzo[...) Show SMILES C[C@@H](c1c(CCN(C)C)sc2ccccc12)c1cccnc1Cl |r| Show InChI InChI=1S/C19H21ClN2S/c1-13(14-8-6-11-21-19(14)20)18-15-7-4-5-9-16(15)23-17(18)10-12-22(2)3/h4-9,11,13H,10,12H2,1-3H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314274 ((-)-(R)-2-(3-(1-(2-methoxypyridin-3-yl)ethyl)benzo...) Show SMILES COc1ncccc1[C@@H](C)c1c(CCN(C)C)sc2ccccc12 |r| Show InChI InChI=1S/C20H24N2OS/c1-14(15-9-7-12-21-20(15)23-4)19-16-8-5-6-10-17(16)24-18(19)11-13-22(2)3/h5-10,12,14H,11,13H2,1-4H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314264 ((-)-(R)-2-(1-(2-(2-(azetidin-1-yl)ethyl)benzo[b]th...) Show SMILES C[C@H](c1c(CCN2CCC2)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C20H22N2S/c1-15(17-8-4-5-11-21-17)20-16-7-2-3-9-18(16)23-19(20)10-14-22-12-6-13-22/h2-5,7-9,11,15H,6,10,12-14H2,1H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297309 ((-)-(R)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)b...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2S/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297309 ((-)-(R)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)b...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2S/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of histamine H1 receptor				Bioorg Med Chem Lett 20: 5874-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.117 BindingDB Entry DOI: 10.7270/Q26W9BDC
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297305 (CHEMBL559251 | Dimethyl-[2-(3-pyrazin-2ylmethyl-1H...) Show SMILES CN(C)CCC1=C(Cc2cnccn2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C18H21N3/c1-21(2)10-7-15-11-14-5-3-4-6-17(14)18(15)12-16-13-19-8-9-20-16/h3-6,8-9,13H,7,10-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314287 ((-)-(R)-2-(3-(1-(1H-pyrazol-1-yl)ethyl)benzo[b]thi...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)n1cccn1 |r| Show InChI InChI=1S/C17H21N3S/c1-13(20-11-6-10-18-20)17-14-7-4-5-8-15(14)21-16(17)9-12-19(2)3/h4-8,10-11,13H,9,12H2,1-3H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50315205 ((R)-2-(6-fluoro-3-(1-(3-methoxypyrazin-2-yl)ethyl)...) Show SMILES COc1nccnc1[C@H](C)C1=C(CCN(C)C)Cc2cc(F)ccc12 |r,c:11| Show InChI InChI=1S/C20H24FN3O/c1-13(19-20(25-4)23-9-8-22-19)18-14(7-10-24(2)3)11-15-12-16(21)5-6-17(15)18/h5-6,8-9,12-13H,7,10-11H2,1-4H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of H2 receptor				Bioorg Med Chem Lett 20: 5874-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.117 BindingDB Entry DOI: 10.7270/Q26W9BDC
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314284 ((-)-(R)-N,N-dimethyl-2-(3-(1-(thiazol-4-yl)ethyl)b...) Show SMILES C[C@@H](c1cscn1)c1c(CCN(C)C)sc2ccccc12 |r| Show InChI InChI=1S/C17H20N2S2/c1-12(14-10-20-11-18-14)17-13-6-4-5-7-15(13)21-16(17)8-9-19(2)3/h4-7,10-12H,8-9H2,1-3H3/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314281 ((+)-(R)-2-(3-(1-(3-methoxypyridin-2-yl)ethyl)benzo...) Show SMILES COc1cccnc1[C@H](C)c1c(CCN(C)C)sc2ccccc12 |r| Show InChI InChI=1S/C20H24N2OS/c1-14(20-16(23-4)9-7-12-21-20)19-15-8-5-6-10-17(15)24-18(19)11-13-22(2)3/h5-10,12,14H,11,13H2,1-4H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50297309 ((-)-(R)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)b...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2S/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]Dofetilide from human ERG				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50314265 (CHEMBL1091776 | N,N-dimethyl-2-(3-(1-(pyridin-3-yl...) Show SMILES CC(c1c(CCN(C)C)sc2ccccc12)c1cccnc1 Show InChI InChI=1S/C19H22N2S/c1-14(15-7-6-11-20-13-15)19-16-8-4-5-9-17(16)22-18(19)10-12-21(2)3/h4-9,11,13-14H,10,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]Dofetilide from human ERG				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314285 ((-)-(R)-N,N-dimethyl-2-(3-(1-(thiazol-5-yl)ethyl)b...) Show SMILES C[C@@H](c1cncs1)c1c(CCN(C)C)sc2ccccc12 |r| Show InChI InChI=1S/C17H20N2S2/c1-12(16-10-18-11-20-16)17-13-6-4-5-7-14(13)21-15(17)8-9-19(2)3/h4-7,10-12H,8-9H2,1-3H3/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50297309 ((-)-(R)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)b...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2S/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50314268 (CHEMBL1091790 | rac-N,N-dimethyl-2-(3-(1-(pyridin-...) Show SMILES CC(c1c(CCN(C)C)sc2ccccc12)c1ccncc1 Show InChI InChI=1S/C19H22N2S/c1-14(15-8-11-20-12-9-15)19-16-6-4-5-7-17(16)22-18(19)10-13-21(2)3/h4-9,11-12,14H,10,13H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50314263 ((-)-(R)-2-(1-(2-(2-(pyrrolidin-1-yl)ethyl)benzo[b]...) Show SMILES C[C@H](c1c(CCN2CCCC2)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C21H24N2S/c1-16(18-9-4-5-12-22-18)21-17-8-2-3-10-19(17)24-20(21)11-15-23-13-6-7-14-23/h2-5,8-10,12,16H,6-7,11,13-15H2,1H3/t16-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314269 ((-)-(R)-2-(3-(1-(3-chloropyridin-2-yl)ethyl)benzo[...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ncccc1Cl |r| Show InChI InChI=1S/C19H21ClN2S/c1-13(19-15(20)8-6-11-21-19)18-14-7-4-5-9-16(14)23-17(18)10-12-22(2)3/h4-9,11,13H,10,12H2,1-3H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314280 ((-)-(R)-N,N-dimethyl-2-(3-(1-(3-methylpyridin-2-yl...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ncccc1C |r| Show InChI InChI=1S/C20H24N2S/c1-14-8-7-12-21-20(14)15(2)19-16-9-5-6-10-17(16)23-18(19)11-13-22(3)4/h5-10,12,15H,11,13H2,1-4H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297306 (CHEMBL540982 | {2-[3-(4-Fluoro-benzyl)-benzo[b]thi...) Show SMILES CN(C)CCc1sc2ccccc2c1Cc1ccc(F)cc1 Show InChI InChI=1S/C19H20FNS/c1-21(2)12-11-19-17(13-14-7-9-15(20)10-8-14)16-5-3-4-6-18(16)22-19/h3-10H,11-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297309 ((-)-(R)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)b...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2S/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314270 ((-)-(R)-2-(3-(1-(5-fluoropyridin-2-yl)ethyl)benzo[...) Show SMILES C[C@H](c1c(CCN(C)C)sc2ccccc12)c1ccc(F)cn1 |r| Show InChI InChI=1S/C19H21FN2S/c1-13(16-9-8-14(20)12-21-16)19-15-6-4-5-7-17(15)23-18(19)10-11-22(2)3/h4-9,12-13H,10-11H2,1-3H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314273 ((-)-(R)-N,N-dimethyl-2-(3-(1-(2-methylpyridin-3-yl...) Show SMILES C[C@@H](c1c(CCN(C)C)sc2ccccc12)c1cccnc1C |r| Show InChI InChI=1S/C20H24N2S/c1-14(16-9-7-12-21-15(16)2)20-17-8-5-6-10-18(17)23-19(20)11-13-22(3)4/h5-10,12,14H,11,13H2,1-4H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50297305 (CHEMBL559251 | Dimethyl-[2-(3-pyrazin-2ylmethyl-1H...) Show SMILES CN(C)CCC1=C(Cc2cnccn2)c2ccccc2C1 |c:5| Show InChI InChI=1S/C18H21N3/c1-21(2)10-7-15-11-14-5-3-4-6-17(14)18(15)12-16-13-19-8-9-20-16/h3-6,8-9,13H,7,10-12H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314283 (CHEMBL1092767 | rac-N,N-dimethyl-2-(3-(1-(thiazol-...) Show SMILES CC(c1nccs1)c1c(CCN(C)C)sc2ccccc12 Show InChI InChI=1S/C17H20N2S2/c1-12(17-18-9-11-20-17)16-13-6-4-5-7-14(13)21-15(16)8-10-19(2)3/h4-7,9,11-12H,8,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314279 (CHEMBL1091793 | rac-2-(3-(1-(6-fluoropyridin-2-yl)...) Show SMILES CC(c1c(CCN(C)C)sc2ccccc12)c1cccc(F)n1 Show InChI InChI=1S/C19H21FN2S/c1-13(15-8-6-10-18(20)21-15)19-14-7-4-5-9-16(14)23-17(19)11-12-22(2)3/h4-10,13H,11-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314278 (CHEMBL1091792 | rac-2-(3-(1-(6-methoxypyridin-2-yl...) Show SMILES COc1cccc(n1)C(C)c1c(CCN(C)C)sc2ccccc12 Show InChI InChI=1S/C20H24N2OS/c1-14(16-9-7-11-19(21-16)23-4)20-15-8-5-6-10-17(15)24-18(20)12-13-22(2)3/h5-11,14H,12-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314271 (CHEMBL1092496 | rac-N,N-dimethyl-2-(3-(1-(6-methyl...) Show SMILES CC(c1c(CCN(C)C)sc2ccccc12)c1ccc(C)nc1 Show InChI InChI=1S/C20H24N2S/c1-14-9-10-16(13-21-14)15(2)20-17-7-5-6-8-18(17)23-19(20)11-12-22(3)4/h5-10,13,15H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297311 (CHEMBL551340 | Dimethyl-[2-(3-pyrazin-2-ylmethyl-b...) Show SMILES CN(C)CCc1sc2ccccc2c1Cc1cnccn1 Show InChI InChI=1S/C17H19N3S/c1-20(2)10-7-17-15(11-13-12-18-8-9-19-13)14-5-3-4-6-16(14)21-17/h3-6,8-9,12H,7,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50297310 ((-)-Dimethyl-{2-[3-((R)-1-pyridin-2-yl-ethyl)-benz...) Show SMILES C[C@H](c1c(CCN(C)C)oc2ccccc12)c1ccccn1 |r| Show InChI InChI=1S/C19H22N2O/c1-14(16-9-6-7-12-20-16)19-15-8-4-5-10-17(15)22-18(19)11-13-21(2)3/h4-10,12,14H,11,13H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]N-methylscopolamine from human muscarinic M3 receptor expressed in CHO Flp-In cells by liquid scintillation counting				J Med Chem 52: 5307-10 (2009) Article DOI: 10.1021/jm900933k BindingDB Entry DOI: 10.7270/Q2057G0S
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314272 (CHEMBL1092812 | rac-2-(3-(1-(6-methoxypyridin-3-yl...) Show SMILES COc1ccc(cn1)C(C)c1c(CCN(C)C)sc2ccccc12 Show InChI InChI=1S/C20H24N2OS/c1-14(15-9-10-19(23-4)21-13-15)20-16-7-5-6-8-17(16)24-18(20)11-12-22(2)3/h5-10,13-14H,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314286 (CHEMBL1093607 | rac-2-(3-(1-(1H-imidazol-1-yl)ethy...) Show SMILES CC(c1c(CCN(C)C)sc2ccccc12)n1ccnc1 Show InChI InChI=1S/C17H21N3S/c1-13(20-11-9-18-12-20)17-14-6-4-5-7-15(14)21-16(17)8-10-19(2)3/h4-7,9,11-13H,8,10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50314277 (CHEMBL1091791 | rac-N,N-dimethyl-2-(3-(1-(4-methyl...) Show SMILES CC(c1c(CCN(C)C)sc2ccccc12)c1cc(C)ccn1 Show InChI InChI=1S/C20H24N2S/c1-14-9-11-21-17(13-14)15(2)20-16-7-5-6-8-18(16)23-19(20)10-12-22(3)4/h5-9,11,13,15H,10,12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells after 90 mins by scintillation counting				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50314268 (CHEMBL1091790 | rac-N,N-dimethyl-2-(3-(1-(pyridin-...) Show SMILES CC(c1c(CCN(C)C)sc2ccccc12)c1ccncc1 Show InChI InChI=1S/C19H22N2S/c1-14(15-8-11-20-12-9-15)19-16-6-4-5-7-17(16)22-18(19)10-13-21(2)3/h4-9,11-12,14H,10,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of recombinant CYP2D6 after 30 mins by fluorescence assay				Bioorg Med Chem Lett 20: 2316-20 (2010) Article DOI: 10.1016/j.bmcl.2010.01.134 BindingDB Entry DOI: 10.7270/Q2P55PG0
					More data for this Ligand-Target Pair

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