Compile Data Set for Download or QSAR

Found 408 hits with Last Name = 'schattel' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398191 (CHEMBL2182085) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(CCCCC2=O)c1 Show InChI InChI=1S/C23H21FN2O2S/c1-14-10-19(24)21(26-23(28)16-8-9-29-13-16)12-20(14)25-17-6-7-18-15(11-17)4-2-3-5-22(18)27/h6-13,25H,2-5H2,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330165 (3-(2,6-dichlorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(=O)C=Cc2c(Cl)cccc2Cl)c1 |w:22.23| Show InChI InChI=1S/C24H17Cl2FN4OS/c1-33-24-30-22(14-5-7-16(27)8-6-14)23(31-24)15-11-12-28-20(13-15)29-21(32)10-9-17-18(25)3-2-4-19(17)26/h2-13H,1H3,(H,30,31)(H,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398456 (CHEMBL2179119) Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1 Show InChI InChI=1S/C28H19FN4O/c29-20-10-6-18(7-11-20)25-26(33-27(32-25)19-8-12-21(34)13-9-19)22-14-15-30-28-23(22)16-24(31-28)17-4-2-1-3-5-17/h1-16,34H,(H,30,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398165 (CHEMBL2182072) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1NC(=O)c1ccoc1 Show InChI InChI=1S/C26H19FN2O3/c27-23-10-8-20(14-24(23)29-26(31)18-11-12-32-15-18)28-19-7-9-22-17(13-19)6-5-16-3-1-2-4-21(16)25(22)30/h1-4,7-15,28H,5-6H2,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50300884 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O3S/c1-33-20-10-6-16(21(15-20)34-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)35-3)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1delta kinase domain by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392175 (CHEMBL2152944) Show SMILES OC[C@@H](O)COc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C24H21F2NO4/c25-16-4-8-23(22(26)10-16)27-17-5-7-20-15(9-17)2-1-14-3-6-19(11-21(14)24(20)30)31-13-18(29)12-28/h3-11,18,27-29H,1-2,12-13H2/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392190 (CHEMBL2152960) Show SMILES OC[C@H](O)COc1ccc2c(CCc3cc(Nc4ccc(F)cc4F)ccc3C2=O)c1 |r| Show InChI InChI=1S/C24H21F2NO4/c25-16-3-8-23(22(26)11-16)27-17-4-6-20-14(9-17)1-2-15-10-19(31-13-18(29)12-28)5-7-21(15)24(20)30/h3-11,18,27-29H,1-2,12-13H2/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50300893 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc([nH]c2-c2ccc(F)cc2)S(C)=O)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O4S/c1-34-20-10-6-16(21(15-20)35-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)36(3)33)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of recombinant CK1delta kinase domain by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398153 (CHEMBL2177215) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C28H21FN2O2/c29-25-15-13-22(17-26(25)31-28(33)19-7-2-1-3-8-19)30-21-12-14-24-20(16-21)11-10-18-6-4-5-9-23(18)27(24)32/h1-9,12-17,30H,10-11H2,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50300884 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O3S/c1-33-20-10-6-16(21(15-20)34-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)35-3)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300888 ((S)-4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl...) Show SMILES CC(C)c1onc(c1-c1ccnc(N[C@@H](C)c2ccccc2)c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H24FN3O/c1-16(2)25-23(24(29-30-25)19-9-11-21(26)12-10-19)20-13-14-27-22(15-20)28-17(3)18-7-5-4-6-8-18/h4-17H,1-3H3,(H,27,28)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398458 (CHEMBL2179117) Show SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1 Show InChI InChI=1S/C29H21FN4OS/c1-36(35)22-13-9-20(10-14-22)28-33-26(19-7-11-21(30)12-8-19)27(34-28)23-15-16-31-29-24(23)17-25(32-29)18-5-3-2-4-6-18/h2-17H,1H3,(H,31,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392177 (CHEMBL2152946) Show SMILES OC[C@H](O)COc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C24H21F2NO4/c25-16-4-8-23(22(26)10-16)27-17-5-7-20-15(9-17)2-1-14-3-6-19(11-21(14)24(20)30)31-13-18(29)12-28/h3-11,18,27-29H,1-2,12-13H2/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392172 (CHEMBL2152941) Show SMILES OCCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C24H21F2NO3/c25-17-5-9-23(22(26)13-17)27-18-6-8-20-16(12-18)3-2-15-4-7-19(30-11-1-10-28)14-21(15)24(20)29/h4-9,12-14,27-28H,1-3,10-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392169 (CHEMBL2152938) Show SMILES Nc1ccccc1Nc1ccc2c(CCc3ccc(OC[C@@H](O)CO)cc3C2=O)c1 |r| Show InChI InChI=1S/C24H24N2O4/c25-22-3-1-2-4-23(22)26-17-8-10-20-16(11-17)6-5-15-7-9-19(12-21(15)24(20)29)30-14-18(28)13-27/h1-4,7-12,18,26-28H,5-6,13-14,25H2/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392181 (CHEMBL2152950) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(OCCCN5CCOCC5)cc4C3=O)c2)c(F)c1 Show InChI InChI=1S/C28H28F2N2O3/c29-21-5-9-27(26(30)17-21)31-22-6-8-24-20(16-22)3-2-19-4-7-23(18-25(19)28(24)33)35-13-1-10-32-11-14-34-15-12-32/h4-9,16-18,31H,1-3,10-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330167 (2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(=O)Cc2ccc(F)cc2)c1 Show InChI InChI=1S/C23H18F2N4OS/c1-31-23-28-21(15-4-8-18(25)9-5-15)22(29-23)16-10-11-26-19(13-16)27-20(30)12-14-2-6-17(24)7-3-14/h2-11,13H,12H2,1H3,(H,28,29)(H,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398166 (CHEMBL2182071) Show SMILES O=C(Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1)c1ccoc1 Show InChI InChI=1S/C26H20N2O3/c29-25-23-7-2-1-4-17(23)8-9-18-14-22(10-11-24(18)25)27-20-5-3-6-21(15-20)28-26(30)19-12-13-31-16-19/h1-7,10-16,27H,8-9H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392178 (CHEMBL2152947) Show SMILES CC1(C)OC[C@@H](CCOc2ccc3CCc4cc(Nc5ccc(F)cc5F)ccc4C(=O)c3c2)O1 |r| Show InChI InChI=1S/C28H27F2NO4/c1-28(2)34-16-22(35-28)11-12-33-21-8-5-17-3-4-18-13-20(7-9-23(18)27(32)24(17)15-21)31-26-10-6-19(29)14-25(26)30/h5-10,13-15,22,31H,3-4,11-12,16H2,1-2H3/t22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398154 (CHEMBL2177214) Show SMILES Cc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C29H24N2O2/c1-19-11-14-24(18-27(19)31-29(33)21-8-3-2-4-9-21)30-23-15-16-26-22(17-23)13-12-20-7-5-6-10-25(20)28(26)32/h2-11,14-18,30H,12-13H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398187 (CHEMBL2182089) Show SMILES Fc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C25H17FN2O3S/c26-21-8-6-17(11-22(21)28-25(30)16-9-10-32-14-16)27-18-5-7-20-23(12-18)31-13-15-3-1-2-4-19(15)24(20)29/h1-12,14,27H,13H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398163 (CHEMBL2182074) Show SMILES O=C(Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1)c1ccsc1 Show InChI InChI=1S/C26H20N2O2S/c29-25-23-7-2-1-4-17(23)8-9-18-14-22(10-11-24(18)25)27-20-5-3-6-21(15-20)28-26(30)19-12-13-31-16-19/h1-7,10-16,27H,8-9H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330164 (CHEMBL1272318 | N-(4-(4-(4-fluorophenyl)-2-(methyl...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)cc1 |w:7.7| Show InChI InChI=1S/C25H21FN4O2S/c1-32-20-10-3-16(4-11-20)5-12-22(31)28-21-15-18(13-14-27-21)24-23(29-25(30-24)33-2)17-6-8-19(26)9-7-17/h3-15H,1-2H3,(H,29,30)(H,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392171 (CHEMBL2152940) Show SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C23H19F2NO3/c24-16-4-8-22(21(25)12-16)26-17-5-7-19-15(11-17)2-1-14-3-6-18(29-10-9-27)13-20(14)23(19)28/h3-8,11-13,26-27H,1-2,9-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392179 (CHEMBL2152948) Show SMILES OC[C@H](O)CCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 |r| Show InChI InChI=1S/C25H23F2NO4/c26-17-4-8-24(23(27)12-17)28-18-5-7-21-16(11-18)2-1-15-3-6-20(13-22(15)25(21)31)32-10-9-19(30)14-29/h3-8,11-13,19,28-30H,1-2,9-10,14H2/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392180 (CHEMBL2152949) Show SMILES Fc1ccc(Nc2ccc3c(CCc4ccc(OCCN5CCOCC5)cc4C3=O)c2)c(F)c1 Show InChI InChI=1S/C27H26F2N2O3/c28-20-4-8-26(25(29)16-20)30-21-5-7-23-19(15-21)2-1-18-3-6-22(17-24(18)27(23)32)34-14-11-31-9-12-33-13-10-31/h3-8,15-17,30H,1-2,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398188 (CHEMBL2182088) Show SMILES Cc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C26H20N2O3S/c1-16-6-7-19(12-23(16)28-26(30)18-10-11-32-15-18)27-20-8-9-22-24(13-20)31-14-17-4-2-3-5-21(17)25(22)29/h2-13,15,27H,14H2,1H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Rattus norvegicus (rat))	BDBM50300893 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc([nH]c2-c2ccc(F)cc2)S(C)=O)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O4S/c1-34-20-10-6-16(21(15-20)35-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)36(3)33)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATP				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398457 (CHEMBL2179118) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1 Show InChI InChI=1S/C29H21FN4O2S/c1-37(35,36)22-13-9-20(10-14-22)28-33-26(19-7-11-21(30)12-8-19)27(34-28)23-15-16-31-29-24(23)17-25(32-29)18-5-3-2-4-6-18/h2-17H,1H3,(H,31,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398150 (CHEMBL2177106) Show SMILES Fc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(CCCCC2=O)c1 Show InChI InChI=1S/C24H21FN2O2/c25-21-13-11-19(27-24(29)16-6-2-1-3-7-16)15-22(21)26-18-10-12-20-17(14-18)8-4-5-9-23(20)28/h1-3,6-7,10-15,26H,4-5,8-9H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398186 (CHEMBL2182090) Show SMILES Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(OCc3ccccc3C2=O)c1 Show InChI InChI=1S/C26H19FN2O3S/c1-15-10-21(27)23(29-26(31)17-8-9-33-14-17)12-22(15)28-18-6-7-20-24(11-18)32-13-16-4-2-3-5-19(16)25(20)30/h2-12,14,28H,13H2,1H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398194 (CHEMBL2182082) Show SMILES O=C(Nc1cccc(Nc2ccc3c(CCCCC3=O)c2)c1)c1ccsc1 Show InChI InChI=1S/C22H20N2O2S/c25-21-7-2-1-4-15-12-19(8-9-20(15)21)23-17-5-3-6-18(13-17)24-22(26)16-10-11-27-14-16/h3,5-6,8-14,23H,1-2,4,7H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398132 (CHEMBL2182099) Show SMILES COc1cccc(c1)C(=O)Nc1cccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c1 Show InChI InChI=1S/C29H24N2O3/c1-34-25-10-4-7-21(17-25)29(33)31-23-9-5-8-22(18-23)30-24-14-15-27-20(16-24)13-12-19-6-2-3-11-26(19)28(27)32/h2-11,14-18,30H,12-13H2,1H3,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330176 (CHEMBL1271777 | N-(4-(4-(4-fluorophenyl)-2-(methyl...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(=O)c2ccco2)c1 Show InChI InChI=1S/C20H15FN4O2S/c1-28-20-24-17(12-4-6-14(21)7-5-12)18(25-20)13-8-9-22-16(11-13)23-19(26)15-3-2-10-27-15/h2-11H,1H3,(H,24,25)(H,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398151 (CHEMBL2177217) Show SMILES Cc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(CCCCC2=O)c1 Show InChI InChI=1S/C25H24N2O2/c1-17-11-12-21(27-25(29)18-7-3-2-4-8-18)16-23(17)26-20-13-14-22-19(15-20)9-5-6-10-24(22)28/h2-4,7-8,11-16,26H,5-6,9-10H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330168 (3-fluoro-N-(4-(4-(4-fluorophenyl)-2-(methylthio)-1...) Show SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(NC(=O)c2ccc(C)c(F)c2)c1 Show InChI InChI=1S/C23H18F2N4OS/c1-13-3-4-16(11-18(13)25)22(30)27-19-12-15(9-10-26-19)21-20(28-23(29-21)31-2)14-5-7-17(24)8-6-14/h3-12H,1-2H3,(H,28,29)(H,26,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398155 (CHEMBL2177213) Show SMILES Fc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(CCc3ccccc3C2=O)c1 Show InChI InChI=1S/C28H21FN2O2/c29-25-15-13-22(31-28(33)19-7-2-1-3-8-19)17-26(25)30-21-12-14-24-20(16-21)11-10-18-6-4-5-9-23(18)27(24)32/h1-9,12-17,30H,10-11H2,(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398173 (CHEMBL2177209) Show SMILES Cc1cccc(c1)C(=O)Nc1cccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)c1 Show InChI InChI=1S/C28H22N2O3/c1-18-6-4-8-19(14-18)28(32)30-22-10-5-9-21(15-22)29-23-12-13-25-26(16-23)33-17-20-7-2-3-11-24(20)27(25)31/h2-16,29H,17H2,1H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398464 (CHEMBL2179115) Show SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccnc2[nH]c(cc12)C1CCCCC1)-c1ccccc1 Show InChI InChI=1S/C28H25FN4/c29-21-13-11-19(12-14-21)25-26(33-27(32-25)20-9-5-2-6-10-20)22-15-16-30-28-23(22)17-24(31-28)18-7-3-1-4-8-18/h2,5-6,9-18H,1,3-4,7-8H2,(H,30,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398466 (CHEMBL2179128) Show SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccnc2[nH]c(cc12)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C28H19FN4/c29-21-13-11-19(12-14-21)25-26(33-27(32-25)20-9-5-2-6-10-20)22-15-16-30-28-23(22)17-24(31-28)18-7-3-1-4-8-18/h1-17H,(H,30,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
University of Tuebingen Curated by ChEMBL					Assay Description Inhibition of p38alpha MAPK				J Med Chem 55: 8429-39 (2012) Article DOI: 10.1021/jm300852w BindingDB Entry DOI: 10.7270/Q2765GGT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330143 (CHEMBL1271774 | N-(4-(1-(3-chloropropyl)-4-(4-fluo...) Show SMILES CSc1nc(c(-c2ccnc(NC(C)=O)c2)n1CCCCl)-c1ccc(F)cc1 Show InChI InChI=1S/C20H20ClFN4OS/c1-13(27)24-17-12-15(8-10-23-17)19-18(14-4-6-16(22)7-5-14)25-20(28-2)26(19)11-3-9-21/h4-8,10,12H,3,9,11H2,1-2H3,(H,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398146 (CHEMBL2177221) Show SMILES Cc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(OCc3ccccc3C2=O)c1 Show InChI InChI=1S/C28H22N2O3/c1-18-11-12-21(30-28(32)19-7-3-2-4-8-19)15-25(18)29-22-13-14-24-26(16-22)33-17-20-9-5-6-10-23(20)27(24)31/h2-16,29H,17H2,1H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398192 (CHEMBL2182084) Show SMILES Fc1ccc(Nc2ccc3c(CCCCC3=O)c2)cc1NC(=O)c1ccsc1 Show InChI InChI=1S/C22H19FN2O2S/c23-19-8-6-17(12-20(19)25-22(27)15-9-10-28-13-15)24-16-5-7-18-14(11-16)3-1-2-4-21(18)26/h5-13,24H,1-4H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330158 (CHEMBL1272162 | N-(4-(4-(4-fluorophenyl)-1-methyl-...) Show SMILES COc1ccc(\C=C\C(=O)Nc2cc(ccn2)-c2c(nc(SC)n2C)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C26H23FN4O2S/c1-31-25(24(30-26(31)34-3)18-7-9-20(27)10-8-18)19-14-15-28-22(16-19)29-23(32)13-6-17-4-11-21(33-2)12-5-17/h4-16H,1-3H3,(H,28,29,32)/b13-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50330147 (CHEMBL1271889 | N-(4-(4-(4-fluorophenyl)-1-(3-iodo...) Show SMILES CSc1nc(c(-c2ccnc(NC(C)=O)c2)n1CCCI)-c1ccc(F)cc1 Show InChI InChI=1S/C20H20FIN4OS/c1-13(27)24-17-12-15(8-10-23-17)19-18(14-4-6-16(21)7-5-14)25-20(28-2)26(19)11-3-9-22/h4-8,10,12H,3,9,11H2,1-2H3,(H,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls University of Tübingen Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based assay				Bioorg Med Chem Lett 20: 6671-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.012 BindingDB Entry DOI: 10.7270/Q2KP82D1
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50300884 ((E)-3-(2,4-Dimethoxy-phenyl)-N-(4-[5-(4-fluoro-phe...) Show SMILES COc1ccc(C=CC(=O)Nc2cc(ccn2)-c2nc(SC)[nH]c2-c2ccc(F)cc2)c(OC)c1 |w:6.5| Show InChI InChI=1S/C26H23FN4O3S/c1-33-20-10-6-16(21(15-20)34-2)7-11-23(32)29-22-14-18(12-13-28-22)25-24(30-26(31-25)35-3)17-4-8-19(27)9-5-17/h4-15H,1-3H3,(H,30,31)(H,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by Cherenkov counting				J Med Chem 52: 7618-30 (2009) Article DOI: 10.1021/jm9005127 BindingDB Entry DOI: 10.7270/Q28K7961
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50398189 (CHEMBL2182087) Show SMILES O=C(Nc1cccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)c1)c1ccsc1 Show InChI InChI=1S/C25H18N2O3S/c28-24-21-7-2-1-4-16(21)14-30-23-13-20(8-9-22(23)24)26-18-5-3-6-19(12-18)27-25(29)17-10-11-31-15-17/h1-13,15,26H,14H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2				J Med Chem 55: 7862-74 (2012) Article DOI: 10.1021/jm300951u BindingDB Entry DOI: 10.7270/Q22J6D1F
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392148 (CHEMBL2152778) Show SMILES COc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C22H17F2NO2/c1-27-17-7-4-13-2-3-14-10-16(6-8-18(14)22(26)19(13)12-17)25-21-9-5-15(23)11-20(21)24/h4-12,25H,2-3H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392161 (CHEMBL2152793) Show SMILES Oc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C21H15F2NO2/c22-14-4-8-20(19(23)10-14)24-15-5-7-17-13(9-15)2-1-12-3-6-16(25)11-18(12)21(17)26/h3-11,24-25H,1-2H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50392167 (CHEMBL2152936) Show SMILES Nc1ccccc1Nc1ccc2c(CCc3ccc(OC[C@H](O)CO)cc3C2=O)c1 |r| Show InChI InChI=1S/C24H24N2O4/c25-22-3-1-2-4-23(22)26-17-8-10-20-16(11-17)6-5-15-7-9-19(12-21(15)24(20)29)30-14-18(28)13-27/h1-4,7-12,18,26-28H,5-6,13-14,25H2/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University Curated by ChEMBL					Assay Description Inhibition of p38alpha by immunosorbent based kinase assay				J Med Chem 55: 5868-77 (2012) Article DOI: 10.1021/jm300327h BindingDB Entry DOI: 10.7270/Q2CV4JTJ
					More data for this Ligand-Target Pair

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