Compile Data Set for Download or QSAR

Found 112 hits with Last Name = 'shioya' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM50250631 (CHEMBL4093489) Show SMILES CCCc1ccc(COc2ccc3C(C)=C(CN4CC(C4)C(O)=O)CCc3c2)c(OC)c1 |t:14| Show InChI InChI=1S/C27H33NO4/c1-4-5-19-6-7-22(26(12-19)31-3)17-32-24-10-11-25-18(2)21(9-8-20(25)13-24)14-28-15-23(16-28)27(29)30/h6-7,10-13,23H,4-5,8-9,14-17H2,1-3H3,(H,29,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	0.574	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [33P]-S1P from human S1P5 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting method				J Med Chem 60: 9508-9530 (2017) Article DOI: 10.1021/acs.jmedchem.7b00785 BindingDB Entry DOI: 10.7270/Q2J968SK
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50250631 (CHEMBL4093489) Show SMILES CCCc1ccc(COc2ccc3C(C)=C(CN4CC(C4)C(O)=O)CCc3c2)c(OC)c1 |t:14| Show InChI InChI=1S/C27H33NO4/c1-4-5-19-6-7-22(26(12-19)31-3)17-32-24-10-11-25-18(2)21(9-8-20(25)13-24)14-28-15-23(16-28)27(29)30/h6-7,10-13,23H,4-5,8-9,14-17H2,1-3H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	0.626	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting method				J Med Chem 60: 9508-9530 (2017) Article DOI: 10.1021/acs.jmedchem.7b00785 BindingDB Entry DOI: 10.7270/Q2J968SK
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Rattus norvegicus)	BDBM50250631 (CHEMBL4093489) Show SMILES CCCc1ccc(COc2ccc3C(C)=C(CN4CC(C4)C(O)=O)CCc3c2)c(OC)c1 |t:14| Show InChI InChI=1S/C27H33NO4/c1-4-5-19-6-7-22(26(12-19)31-3)17-32-24-10-11-25-18(2)21(9-8-20(25)13-24)14-28-15-23(16-28)27(29)30/h6-7,10-13,23H,4-5,8-9,14-17H2,1-3H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	0.772	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [33P]-S1P from rat S1P1 receptor after 60 mins by scintillation counting method				J Med Chem 60: 9508-9530 (2017) Article DOI: 10.1021/acs.jmedchem.7b00785 BindingDB Entry DOI: 10.7270/Q2J968SK
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50250631 (CHEMBL4093489) Show SMILES CCCc1ccc(COc2ccc3C(C)=C(CN4CC(C4)C(O)=O)CCc3c2)c(OC)c1 |t:14| Show InChI InChI=1S/C27H33NO4/c1-4-5-19-6-7-22(26(12-19)31-3)17-32-24-10-11-25-18(2)21(9-8-20(25)13-24)14-28-15-23(16-28)27(29)30/h6-7,10-13,23H,4-5,8-9,14-17H2,1-3H3,(H,29,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [33P]-S1P from human S1P4 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting method				J Med Chem 60: 9508-9530 (2017) Article DOI: 10.1021/acs.jmedchem.7b00785 BindingDB Entry DOI: 10.7270/Q2J968SK
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human))	BDBM50250631 (CHEMBL4093489) Show SMILES CCCc1ccc(COc2ccc3C(C)=C(CN4CC(C4)C(O)=O)CCc3c2)c(OC)c1 |t:14| Show InChI InChI=1S/C27H33NO4/c1-4-5-19-6-7-22(26(12-19)31-3)17-32-24-10-11-25-18(2)21(9-8-20(25)13-24)14-28-15-23(16-28)27(29)30/h6-7,10-13,23H,4-5,8-9,14-17H2,1-3H3,(H,29,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	>5.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [33P]-S1P from human S1P2 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting method				J Med Chem 60: 9508-9530 (2017) Article DOI: 10.1021/acs.jmedchem.7b00785 BindingDB Entry DOI: 10.7270/Q2J968SK
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50250631 (CHEMBL4093489) Show SMILES CCCc1ccc(COc2ccc3C(C)=C(CN4CC(C4)C(O)=O)CCc3c2)c(OC)c1 |t:14| Show InChI InChI=1S/C27H33NO4/c1-4-5-19-6-7-22(26(12-19)31-3)17-32-24-10-11-25-18(2)21(9-8-20(25)13-24)14-28-15-23(16-28)27(29)30/h6-7,10-13,23H,4-5,8-9,14-17H2,1-3H3,(H,29,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	>5.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting method				J Med Chem 60: 9508-9530 (2017) Article DOI: 10.1021/acs.jmedchem.7b00785 BindingDB Entry DOI: 10.7270/Q2J968SK
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347145 (CHEMBL1797507) Show SMILES OC(=O)CCNCC1=Cc2ccc(OCCCCc3ccccc3)cc2CC1 |t:7| Show InChI InChI=1S/C24H29NO3/c26-24(27)13-14-25-18-20-9-10-22-17-23(12-11-21(22)16-20)28-15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,11-12,16-17,25H,4-5,8-10,13-15,18H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347146 (CHEMBL1797508) Show SMILES CC1=C(CNCCC(O)=O)CCc2cc(OCCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C25H31NO3/c1-19-22(18-26-15-14-25(27)28)11-10-21-17-23(12-13-24(19)21)29-16-6-5-9-20-7-3-2-4-8-20/h2-4,7-8,12-13,17,26H,5-6,9-11,14-16,18H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347147 (CHEMBL1797509) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C26H31NO3/c1-19-22(16-27-17-23(18-27)26(28)29)11-10-21-15-24(12-13-25(19)21)30-14-6-5-9-20-7-3-2-4-8-20/h2-4,7-8,12-13,15,23H,5-6,9-11,14,16-18H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347148 (CHEMBL1797510) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCCc2cc(OCCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C27H33NO3/c1-20-23(17-28-18-24(19-28)27(29)30)12-7-11-22-16-25(13-14-26(20)22)31-15-6-5-10-21-8-3-2-4-9-21/h2-4,8-9,13-14,16,24H,5-7,10-12,15,17-19H2,1H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50337599 ((E/Z)-3-(3-(4-(3-phenylpropoxy)phenyl)allylamino)p...) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCc2ccccc2)cc1 Show InChI InChI=1S/C21H25NO3/c23-21(24)14-16-22-15-4-8-19-10-12-20(13-11-19)25-17-5-9-18-6-2-1-3-7-18/h1-4,6-8,10-13,22H,5,9,14-17H2,(H,23,24)/b8-4+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347149 (CHEMBL1797414) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCCc2ccccc2)cc1 Show InChI InChI=1S/C22H27NO3/c24-22(25)15-17-23-16-6-10-20-11-13-21(14-12-20)26-18-5-4-9-19-7-2-1-3-8-19/h1-3,6-8,10-14,23H,4-5,9,15-18H2,(H,24,25)/b10-6+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347150 (CHEMBL1797499) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCCCc2ccccc2)cc1 Show InChI InChI=1S/C23H29NO3/c25-23(26)16-18-24-17-7-11-21-12-14-22(15-13-21)27-19-6-2-5-10-20-8-3-1-4-9-20/h1,3-4,7-9,11-15,24H,2,5-6,10,16-19H2,(H,25,26)/b11-7+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347151 (CHEMBL1797500) Show SMILES Cc1cc(\C=C\CNCCC(O)=O)ccc1OCCCCc1ccccc1 Show InChI InChI=1S/C23H29NO3/c1-19-18-21(11-7-15-24-16-14-23(25)26)12-13-22(19)27-17-6-5-10-20-8-3-2-4-9-20/h2-4,7-9,11-13,18,24H,5-6,10,14-17H2,1H3,(H,25,26)/b11-7+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347152 (CHEMBL1797501) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCCc2ccccc2)cc1Cl Show InChI InChI=1S/C22H26ClNO3/c23-21-17-20(27-16-5-4-9-18-7-2-1-3-8-18)12-11-19(21)10-6-14-24-15-13-22(25)26/h1-3,6-8,10-12,17,24H,4-5,9,13-16H2,(H,25,26)/b10-6+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347153 (CHEMBL1797502) Show SMILES COc1cc(OCCCCc2ccccc2)ccc1\C=C\CNCCC(O)=O Show InChI InChI=1S/C23H29NO4/c1-27-22-18-21(28-17-6-5-10-19-8-3-2-4-9-19)13-12-20(22)11-7-15-24-16-14-23(25)26/h2-4,7-9,11-13,18,24H,5-6,10,14-17H2,1H3,(H,25,26)/b11-7+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347154 (CHEMBL1797503) Show SMILES Cc1cc(OCCCCc2ccccc2)ccc1\C=C\CNCCC(O)=O Show InChI InChI=1S/C23H29NO3/c1-19-18-22(27-17-6-5-10-20-8-3-2-4-9-20)13-12-21(19)11-7-15-24-16-14-23(25)26/h2-4,7-9,11-13,18,24H,5-6,10,14-17H2,1H3,(H,25,26)/b11-7+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347155 (CHEMBL1797504) Show SMILES OC(=O)C1CN(C\C=C\c2ccc(OCCCc3ccccc3)cc2)C1 Show InChI InChI=1S/C22H25NO3/c24-22(25)20-16-23(17-20)14-4-8-19-10-12-21(13-11-19)26-15-5-9-18-6-2-1-3-7-18/h1-4,6-8,10-13,20H,5,9,14-17H2,(H,24,25)/b8-4+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347156 (CHEMBL1797505) Show SMILES OC(=O)C1CCN(C\C=C\c2ccc(OCCCc3ccccc3)cc2)CC1 Show InChI InChI=1S/C24H29NO3/c26-24(27)22-14-17-25(18-15-22)16-4-8-21-10-12-23(13-11-21)28-19-5-9-20-6-2-1-3-7-20/h1-4,6-8,10-13,22H,5,9,14-19H2,(H,26,27)/b8-4+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347157 (CHEMBL1797506) Show SMILES C\C(CNCCC(O)=O)=C/c1ccc(OCCCCc2ccccc2)cc1 Show InChI InChI=1S/C23H29NO3/c1-19(18-24-15-14-23(25)26)17-21-10-12-22(13-11-21)27-16-6-5-9-20-7-3-2-4-8-20/h2-4,7-8,10-13,17,24H,5-6,9,14-16,18H2,1H3,(H,25,26)/b19-17+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347145 (CHEMBL1797507) Show SMILES OC(=O)CCNCC1=Cc2ccc(OCCCCc3ccccc3)cc2CC1 |t:7| Show InChI InChI=1S/C24H29NO3/c26-24(27)13-14-25-18-20-9-10-22-17-23(12-11-21(22)16-20)28-15-5-4-8-19-6-2-1-3-7-19/h1-3,6-7,11-12,16-17,25H,4-5,8-10,13-15,18H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347146 (CHEMBL1797508) Show SMILES CC1=C(CNCCC(O)=O)CCc2cc(OCCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C25H31NO3/c1-19-22(18-26-15-14-25(27)28)11-10-21-17-23(12-13-24(19)21)29-16-6-5-9-20-7-3-2-4-8-20/h2-4,7-8,12-13,17,26H,5-6,9-11,14-16,18H2,1H3,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347147 (CHEMBL1797509) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C26H31NO3/c1-19-22(16-27-17-23(18-27)26(28)29)11-10-21-15-24(12-13-25(19)21)30-14-6-5-9-20-7-3-2-4-8-20/h2-4,7-8,12-13,15,23H,5-6,9-11,14,16-18H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50347148 (CHEMBL1797510) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCCc2cc(OCCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C27H33NO3/c1-20-23(17-28-18-24(19-28)27(29)30)12-7-11-22-16-25(13-14-26(20)22)31-15-6-5-10-21-8-3-2-4-9-21/h2-4,8-9,13-14,16,24H,5-7,10-12,15,17-19H2,1H3,(H,29,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50337599 ((E/Z)-3-(3-(4-(3-phenylpropoxy)phenyl)allylamino)p...) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCc2ccccc2)cc1 Show InChI InChI=1S/C21H25NO3/c23-21(24)14-16-22-15-4-8-19-10-12-20(13-11-19)25-17-5-9-18-6-2-1-3-7-18/h1-4,6-8,10-13,22H,5,9,14-17H2,(H,23,24)/b8-4+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347150 (CHEMBL1797499) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCCCc2ccccc2)cc1 Show InChI InChI=1S/C23H29NO3/c25-23(26)16-18-24-17-7-11-21-12-14-22(15-13-21)27-19-6-2-5-10-20-8-3-1-4-9-20/h1,3-4,7-9,11-15,24H,2,5-6,10,16-19H2,(H,25,26)/b11-7+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347151 (CHEMBL1797500) Show SMILES Cc1cc(\C=C\CNCCC(O)=O)ccc1OCCCCc1ccccc1 Show InChI InChI=1S/C23H29NO3/c1-19-18-21(11-7-15-24-16-14-23(25)26)12-13-22(19)27-17-6-5-10-20-8-3-2-4-9-20/h2-4,7-9,11-13,18,24H,5-6,10,14-17H2,1H3,(H,25,26)/b11-7+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347152 (CHEMBL1797501) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCCc2ccccc2)cc1Cl Show InChI InChI=1S/C22H26ClNO3/c23-21-17-20(27-16-5-4-9-18-7-2-1-3-8-18)12-11-19(21)10-6-14-24-15-13-22(25)26/h1-3,6-8,10-12,17,24H,4-5,9,13-16H2,(H,25,26)/b10-6+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347153 (CHEMBL1797502) Show SMILES COc1cc(OCCCCc2ccccc2)ccc1\C=C\CNCCC(O)=O Show InChI InChI=1S/C23H29NO4/c1-27-22-18-21(28-17-6-5-10-19-8-3-2-4-9-19)13-12-20(22)11-7-15-24-16-14-23(25)26/h2-4,7-9,11-13,18,24H,5-6,10,14-17H2,1H3,(H,25,26)/b11-7+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347154 (CHEMBL1797503) Show SMILES Cc1cc(OCCCCc2ccccc2)ccc1\C=C\CNCCC(O)=O Show InChI InChI=1S/C23H29NO3/c1-19-18-22(27-17-6-5-10-20-8-3-2-4-9-20)13-12-21(19)11-7-15-24-16-14-23(25)26/h2-4,7-9,11-13,18,24H,5-6,10,14-17H2,1H3,(H,25,26)/b11-7+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347155 (CHEMBL1797504) Show SMILES OC(=O)C1CN(C\C=C\c2ccc(OCCCc3ccccc3)cc2)C1 Show InChI InChI=1S/C22H25NO3/c24-22(25)20-16-23(17-20)14-4-8-19-10-12-21(13-11-19)26-15-5-9-18-6-2-1-3-7-18/h1-4,6-8,10-13,20H,5,9,14-17H2,(H,24,25)/b8-4+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347156 (CHEMBL1797505) Show SMILES OC(=O)C1CCN(C\C=C\c2ccc(OCCCc3ccccc3)cc2)CC1 Show InChI InChI=1S/C24H29NO3/c26-24(27)22-14-17-25(18-15-22)16-4-8-21-10-12-23(13-11-21)28-19-5-9-20-6-2-1-3-7-20/h1-4,6-8,10-13,22H,5,9,14-19H2,(H,26,27)/b8-4+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347157 (CHEMBL1797506) Show SMILES C\C(CNCCC(O)=O)=C/c1ccc(OCCCCc2ccccc2)cc1 Show InChI InChI=1S/C23H29NO3/c1-19(18-24-15-14-23(25)26)17-21-10-12-22(13-11-21)27-16-6-5-9-20-7-3-2-4-8-20/h2-4,7-8,10-13,17,24H,5-6,9,14-16,18H2,1H3,(H,25,26)/b19-17+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50347149 (CHEMBL1797414) Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCCc2ccccc2)cc1 Show InChI InChI=1S/C22H27NO3/c24-22(25)15-17-23-16-6-10-20-11-13-21(14-12-20)26-18-5-4-9-19-7-2-1-3-8-19/h1-3,6-8,10-14,23H,4-5,9,15-18H2,(H,24,25)/b10-6+	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels				Bioorg Med Chem Lett 21: 3885-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.029 BindingDB Entry DOI: 10.7270/Q2NS0V7X
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361036 (CHEMBL1935575) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C25H29NO3/c1-18-21(15-26-16-22(17-26)25(27)28)10-9-20-14-23(11-12-24(18)20)29-13-5-8-19-6-3-2-4-7-19/h2-4,6-7,11-12,14,22H,5,8-10,13,15-17H2,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361037 (CHEMBL1935576) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3ccc(F)cc3)ccc12 |c:1| Show InChI InChI=1S/C25H28FNO3/c1-17-20(14-27-15-21(16-27)25(28)29)7-6-19-13-23(10-11-24(17)19)30-12-2-3-18-4-8-22(26)9-5-18/h4-5,8-11,13,21H,2-3,6-7,12,14-16H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.840	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361038 (CHEMBL1935577) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3cccc(F)c3)ccc12 |c:1| Show InChI InChI=1S/C25H28FNO3/c1-17-20(14-27-15-21(16-27)25(28)29)8-7-19-13-23(9-10-24(17)19)30-11-3-5-18-4-2-6-22(26)12-18/h2,4,6,9-10,12-13,21H,3,5,7-8,11,14-16H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361039 (CHEMBL1935578) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3ccccc3F)ccc12 |c:1| Show InChI InChI=1S/C25H28FNO3/c1-17-20(14-27-15-21(16-27)25(28)29)9-8-19-13-22(10-11-23(17)19)30-12-4-6-18-5-2-3-7-24(18)26/h2-3,5,7,10-11,13,21H,4,6,8-9,12,14-16H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361040 (CHEMBL1935579) Show SMILES CC(CCOc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1)c1ccccc1 |t:10| Show InChI InChI=1S/C26H31NO3/c1-18(20-6-4-3-5-7-20)12-13-30-24-10-11-25-19(2)22(9-8-21(25)14-24)15-27-16-23(17-27)26(28)29/h3-7,10-11,14,18,23H,8-9,12-13,15-17H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361041 (CHEMBL1935580) Show SMILES CC(COc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1)Cc1ccccc1 |t:9| Show InChI InChI=1S/C26H31NO3/c1-18(12-20-6-4-3-5-7-20)17-30-24-10-11-25-19(2)22(9-8-21(25)13-24)14-27-15-23(16-27)26(28)29/h3-7,10-11,13,18,23H,8-9,12,14-17H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.660	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361042 (CHEMBL1935581) Show SMILES CC(CCc1ccccc1)Oc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1 |t:17| Show InChI InChI=1S/C26H31NO3/c1-18(8-9-20-6-4-3-5-7-20)30-24-12-13-25-19(2)22(11-10-21(25)14-24)15-27-16-23(17-27)26(28)29/h3-7,12-14,18,23H,8-11,15-17H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361043 (CHEMBL1935582) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCC(C)(C)Cc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C27H33NO3/c1-19-22(15-28-16-23(17-28)26(29)30)10-9-21-13-24(11-12-25(19)21)31-18-27(2,3)14-20-7-5-4-6-8-20/h4-8,11-13,23H,9-10,14-18H2,1-3H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361044 (CHEMBL1935583) Show SMILES C[C@@H](COc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1)Cc1ccc(F)cc1 |r,t:9| Show InChI InChI=1S/C26H30FNO3/c1-17(11-19-3-7-23(27)8-4-19)16-31-24-9-10-25-18(2)21(6-5-20(25)12-24)13-28-14-22(15-28)26(29)30/h3-4,7-10,12,17,22H,5-6,11,13-16H2,1-2H3,(H,29,30)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.850	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361045 (CHEMBL1935584) Show SMILES C[C@H](COc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1)Cc1ccc(F)cc1 |r,t:9| Show InChI InChI=1S/C26H30FNO3/c1-17(11-19-3-7-23(27)8-4-19)16-31-24-9-10-25-18(2)21(6-5-20(25)12-24)13-28-14-22(15-28)26(29)30/h3-4,7-10,12,17,22H,5-6,11,13-16H2,1-2H3,(H,29,30)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.370	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361046 (CHEMBL1935585) Show SMILES CC[C@H](COc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1)Cc1ccc(F)cc1 |r,t:10| Show InChI InChI=1S/C27H32FNO3/c1-3-19(12-20-4-8-24(28)9-5-20)17-32-25-10-11-26-18(2)22(7-6-21(26)13-25)14-29-15-23(16-29)27(30)31/h4-5,8-11,13,19,23H,3,6-7,12,14-17H2,1-2H3,(H,30,31)/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361047 (CHEMBL1935586) Show SMILES CC(C)[C@H](COc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1)Cc1ccc(F)cc1 |r,t:11| Show InChI InChI=1S/C28H34FNO3/c1-18(2)23(12-20-4-8-25(29)9-5-20)17-33-26-10-11-27-19(3)22(7-6-21(27)13-26)14-30-15-24(16-30)28(31)32/h4-5,8-11,13,18,23-24H,6-7,12,14-17H2,1-3H3,(H,31,32)/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50361048 (CHEMBL1935587) Show SMILES C[C@H](COc1ccc2C(C)=C(CN3CC(C3)C(O)=O)CCc2c1)Cc1ccc(Cl)cc1 |r,t:9| Show InChI InChI=1S/C26H30ClNO3/c1-17(11-19-3-7-23(27)8-4-19)16-31-24-9-10-25-18(2)21(6-5-20(25)12-24)13-28-14-22(15-28)26(29)30/h3-4,7-10,12,17,22H,5-6,11,13-16H2,1-2H3,(H,29,30)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.550	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50361036 (CHEMBL1935575) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3ccccc3)ccc12 |c:1| Show InChI InChI=1S/C25H29NO3/c1-18-21(15-26-16-22(17-26)25(27)28)10-9-20-14-23(11-12-24(18)20)29-13-5-8-19-6-3-2-4-7-19/h2-4,6-7,11-12,14,22H,5,8-10,13,15-17H2,1H3,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50361037 (CHEMBL1935576) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3ccc(F)cc3)ccc12 |c:1| Show InChI InChI=1S/C25H28FNO3/c1-17-20(14-27-15-21(16-27)25(28)29)7-6-19-13-23(10-11-24(17)19)30-12-2-3-18-4-8-22(26)9-5-18/h4-5,8-11,13,21H,2-3,6-7,12,14-16H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50361038 (CHEMBL1935577) Show SMILES CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3cccc(F)c3)ccc12 |c:1| Show InChI InChI=1S/C25H28FNO3/c1-17-20(14-27-15-21(16-27)25(28)29)8-7-19-13-23(9-10-24(17)19)30-11-3-5-18-4-2-6-22(26)12-18/h2,4,6,9-10,12-13,21H,3,5,7-8,11,14-16H2,1H3,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as induction of intracellular calcium level				Bioorg Med Chem Lett 22: 144-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.048 BindingDB Entry DOI: 10.7270/Q28G8M46
					More data for this Ligand-Target Pair

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