Compile Data Set for Download or QSAR

Found 42 hits with Last Name = 'tan' and Initial = 'pz'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113332 (3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1 Show InChI InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor in humans				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50095027 ((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...) Show SMILES COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC |r| Show InChI InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor in humans				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113325 ((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2cccc(I)c2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-6-4-16(5-7-18)20(24)17-9-12-23(13-10-17)11-8-15-2-1-3-19(22)14-15/h1-7,14,17H,8-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113330 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES OC(C1CCN(CCc2ccccc2I)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17,20,24H,9-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113333 ((4-Nitro-phenyl)-(1-phenethyl-piperidin-4-yl)-meth...) Show SMILES OC(C1CCN(CCc2ccccc2)CC1)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C20H24N2O3/c23-20(17-6-8-19(9-7-17)22(24)25)18-11-14-21(15-12-18)13-10-16-4-2-1-3-5-16/h1-9,18,20,23H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113329 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES OC(C1CCN(CCc2ccc(F)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17,20,24H,9-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113324 ((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccc(I)cc2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-5-3-16(4-6-18)20(24)17-10-13-23(14-11-17)12-9-15-1-7-19(22)8-2-15/h1-8,17H,9-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50113324 ((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccc(I)cc2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-5-3-16(4-6-18)20(24)17-10-13-23(14-11-17)12-9-15-1-7-19(22)8-2-15/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50113325 ((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2cccc(I)c2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-6-4-16(5-7-18)20(24)17-9-12-23(13-10-17)11-8-15-2-1-3-19(22)14-15/h1-7,14,17H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113339 ((4-Nitro-phenyl)-(1-phenethyl-piperidin-4-yl)-meth...) Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)C1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C20H22N2O3/c23-20(17-6-8-19(9-7-17)22(24)25)18-11-14-21(15-12-18)13-10-16-4-2-1-3-5-16/h1-9,18H,10-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113326 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES Fc1ccc(CCN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C20H21F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17H,9-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113328 ((4-Fluoro-phenyl)-[1-(3-iodo-benzyl)-piperidin-4-y...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(Cc2cccc(I)c2)CC1 Show InChI InChI=1S/C19H19FINO/c20-17-6-4-15(5-7-17)19(23)16-8-10-22(11-9-16)13-14-2-1-3-18(21)12-14/h1-7,12,16H,8-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113340 ((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...) Show SMILES OC(C1CCN(CCc2cccc(I)c2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23FINO/c21-18-6-4-16(5-7-18)20(24)17-9-12-23(13-10-17)11-8-15-2-1-3-19(22)14-15/h1-7,14,17,20,24H,8-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50113325 ((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2cccc(I)c2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-6-4-16(5-7-18)20(24)17-9-12-23(13-10-17)11-8-15-2-1-3-19(22)14-15/h1-7,14,17H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50113330 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES OC(C1CCN(CCc2ccccc2I)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113337 ((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...) Show SMILES OC(C1CCN(CCc2ccc(I)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23FINO/c21-18-5-3-16(4-6-18)20(24)17-10-13-23(14-11-17)12-9-15-1-7-19(22)8-2-15/h1-8,17,20,24H,9-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	35.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50113325 ((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2cccc(I)c2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-6-4-16(5-7-18)20(24)17-9-12-23(13-10-17)11-8-15-2-1-3-19(22)14-15/h1-7,14,17H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	48.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50113325 ((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2cccc(I)c2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-6-4-16(5-7-18)20(24)17-9-12-23(13-10-17)11-8-15-2-1-3-19(22)14-15/h1-7,14,17H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	51.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50113326 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES Fc1ccc(CCN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C20H21F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50113330 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES OC(C1CCN(CCc2ccccc2I)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50113331 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50113324 ((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccc(I)cc2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-5-3-16(4-6-18)20(24)17-10-13-23(14-11-17)12-9-15-1-7-19(22)8-2-15/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	144	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50113324 ((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccc(I)cc2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-5-3-16(4-6-18)20(24)17-10-13-23(14-11-17)12-9-15-1-7-19(22)8-2-15/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113338 ((4-Fluoro-phenyl)-[1-(2-iodo-benzyl)-piperidin-4-y...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(Cc2ccccc2I)CC1 Show InChI InChI=1S/C19H19FINO/c20-17-7-5-14(6-8-17)19(23)15-9-11-22(12-10-15)13-16-3-1-2-4-18(16)21/h1-8,15H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113336 ((4-Fluoro-phenyl)-[1-(4-iodo-benzyl)-piperidin-4-y...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(Cc2ccc(I)cc2)CC1 Show InChI InChI=1S/C19H19FINO/c20-17-5-3-15(4-6-17)19(23)16-9-11-22(12-10-16)13-14-1-7-18(21)8-2-14/h1-8,16H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	227	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50113324 ((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCc2ccc(I)cc2)CC1 Show InChI InChI=1S/C20H21FINO/c21-18-5-3-16(4-6-18)20(24)17-10-13-23(14-11-17)12-9-15-1-7-19(22)8-2-15/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50113330 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES OC(C1CCN(CCc2ccccc2I)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50113326 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES Fc1ccc(CCN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C20H21F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	453	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50113326 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES Fc1ccc(CCN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C20H21F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	493	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50113329 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES OC(C1CCN(CCc2ccc(F)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	503	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50113329 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES OC(C1CCN(CCc2ccc(F)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50113326 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES Fc1ccc(CCN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C20H21F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113334 ((4-Fluoro-phenyl)-[1-(3-iodo-benzyl)-piperidin-4-y...) Show SMILES OC(C1CCN(Cc2cccc(I)c2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C19H21FINO/c20-17-6-4-15(5-7-17)19(23)16-8-10-22(11-9-16)13-14-2-1-3-18(21)12-14/h1-7,12,16,19,23H,8-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50113329 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES OC(C1CCN(CCc2ccc(F)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113327 ((4-Fluoro-phenyl)-[1-(2-iodo-benzyl)-piperidin-4-y...) Show SMILES OC(C1CCN(Cc2ccccc2I)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C19H21FINO/c20-17-7-5-14(6-8-17)19(23)15-9-11-22(12-10-15)13-16-3-1-2-4-18(16)21/h1-8,15,19,23H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50113335 ((4-Fluoro-phenyl)-[1-(4-iodo-benzyl)-piperidin-4-y...) Show SMILES OC(C1CCN(Cc2ccc(I)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C19H21FINO/c20-17-5-3-15(4-6-17)19(23)16-9-11-22(12-10-16)13-14-1-7-18(21)8-2-14/h1-8,16,19,23H,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50113329 ((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...) Show SMILES OC(C1CCN(CCc2ccc(F)cc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSD				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50113330 ((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...) Show SMILES OC(C1CCN(CCc2ccccc2I)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H23FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17,20,24H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...				J Med Chem 45: 2319-24 (2002) BindingDB Entry DOI: 10.7270/Q2B27TM2
					More data for this Ligand-Target Pair