BindingDB PrimarySearch

Found 636 hits with Last Name = 'terefenko' and Initial = 'ea'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cells				J Med Chem 54: 6824-31 (2011) Article DOI: 10.1021/jm200733r BindingDB Entry DOI: 10.7270/Q2XD1227
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50066523 (2,2,4-Trimethyl-6-(3-nitro-phenyl)-1,2-dihydro-qui...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-WIN-35428 from human DAT expressed in CHO cells				J Med Chem 54: 6824-31 (2011) Article DOI: 10.1021/jm200733r BindingDB Entry DOI: 10.7270/Q2XD1227
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50005536 (42-548 \| 5-(4-Chloro-phenyl)-2,5-dihydro-3H-imidaz...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	22.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to human recombinant DAT expressed in CHO cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105572 (1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimida...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105564 (6-(3-Chloro-phenyl)-3H-benzothiazol-2-one \| CHEMBL...) Show SMILES Clc1cccc(c1)-c1ccc2[nH]c(=O)sc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell line				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105561 (1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105566 (6-(3-Nitro-phenyl)-3H-benzothiazol-2-one \| CHEMBL3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	332	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105563 (1-Benzyl-6-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	521	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105560 (1-Isopropyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoim...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	525	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105565 (6-(3-Chloro-phenyl)-1-isopropyl-1,3-dihydro-benzoi...) Show SMILES CC(C)n1c2cc(ccc2[nH]c1=O)-c1cccc(Cl)c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	525	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105562 (1-Benzyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimida...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	714	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105559 (1-Benzyl-5-(3-chloro-phenyl)-1,3-dihydro-benzoimid...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105567 (1-Benzyl-5-(3-nitro-phenyl)-1,3-dihydro-benzoimida...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell line				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50105568 (1-Methyl-6-(3-nitro-phenyl)-1,3-dihydro-benzoimida...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Binding affinity towards progesterone receptor was measured				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Women's Health Research Institute Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell line				J Med Chem 45: 4379-82 (2002) BindingDB Entry DOI: 10.7270/Q22F7P5W
Women's Health Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell line				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of progesterone receptor mediated progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonistic activity against Progesterone receptor (PR) in transcriptional activation assay in human T47D breast carcinoma cell line				Bioorg Med Chem Lett 12: 787-90 (2002) BindingDB Entry DOI: 10.7270/Q2WS8TSW
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration against progesterone induced PRE-luciferase activity in CV-cells				Bioorg Med Chem Lett 11: 2747-50 (2001) BindingDB Entry DOI: 10.7270/Q2222V92
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Women's Health Research Institute Curated by ChEMBL					Assay Description Antagonist activity against the Progesterone Receptor (PR)				J Med Chem 45: 4379-82 (2002) BindingDB Entry DOI: 10.7270/Q22F7P5W
Women's Health Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Women's Health Research Institute Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor (PR) using PRE-luciferase plasmid co-transfected CV-1 cells				J Med Chem 45: 4379-82 (2002) BindingDB Entry DOI: 10.7270/Q22F7P5W
Women's Health Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor by Gal4-DNA binding domain-hormone receptor LBD one-hybrid assay				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at cloned glucocorticoid receptor-ligand binding domain expressed in african green monkey COS7 cells by GAL4 luciferase reporter ...				Bioorg Med Chem 16: 6589-600 (2008) Article DOI: 10.1016/j.bmc.2008.05.018 BindingDB Entry DOI: 10.7270/Q2V125QZ
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Women's Health Research Institute Curated by ChEMBL					Assay Description Antagonist activity against the Glucocorticoid Receptor (GR)				J Med Chem 45: 4379-82 (2002) BindingDB Entry DOI: 10.7270/Q22F7P5W
Women's Health Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50319578 ((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cells				J Med Chem 54: 6824-31 (2011) Article DOI: 10.1021/jm200733r BindingDB Entry DOI: 10.7270/Q2XD1227
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264285 (1-methyl-5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from progesterone receptor in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50118693 (6-(3-Chloro-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Women's Health Research Institute Curated by ChEMBL					Assay Description Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cells				J Med Chem 45: 4379-82 (2002) BindingDB Entry DOI: 10.7270/Q22F7P5W
Women's Health Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50110505 (4-methyl-5-(2-methyl-1,2-dihydrospiro[3,1-benzoxaz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against progesterone receptor using human T47D breast carcinoma cell line				Bioorg Med Chem Lett 12: 787-90 (2002) BindingDB Entry DOI: 10.7270/Q2WS8TSW
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50319583 ((2R)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human NET expressed in MDCK-Net6 cells assessed as inhibition of norepinephrine uptake				J Med Chem 54: 6824-31 (2011) Article DOI: 10.1021/jm200733r BindingDB Entry DOI: 10.7270/Q2XD1227
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 18: 6067-70 (2008) Article DOI: 10.1016/j.bmcl.2008.10.026 BindingDB Entry DOI: 10.7270/Q2JD4XQT
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM84745 (CAS_136434-34-9 \| DULOXETINE \| LY-248686 \| LY24868...) Show SMILES CNCC[C@H](Oc1cccc2ccccc12)c1cccs1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50124566 ((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...) Show SMILES CCOc1ccccc1OC(C1CNCCO1)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50126111 (4-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-benzo[d][1...) Show SMILES CC1(C)OC(=S)Nc2ccc(cc12)-c1csc(c1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]P4 to progesterone receptor (PR) of human T47D breast carcinoma cells				Bioorg Med Chem Lett 13: 1313-6 (2003) BindingDB Entry DOI: 10.7270/Q2SN09HR
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50124566 ((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...) Show SMILES CCOc1ccccc1OC(C1CNCCO1)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 18: 6067-70 (2008) Article DOI: 10.1016/j.bmcl.2008.10.026 BindingDB Entry DOI: 10.7270/Q2JD4XQT
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50259277 ((R,S/S,R)-syn-1-((4-methoxyphenyl)(methyl)amino)-3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50370475 (S,S-REBOXETINE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50124566 ((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...) Show SMILES CCOc1ccccc1OC(C1CNCCO1)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50169361 (3-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Progesterone receptor agonist activity in human T47D breast carcinoma cell alkaline phosphatase assay				Bioorg Med Chem Lett 15: 3600-3 (2005) Article DOI: 10.1016/j.bmcl.2005.05.082 BindingDB Entry DOI: 10.7270/Q23J3CHG
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 19: 5807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.07.050 BindingDB Entry DOI: 10.7270/Q2H70FV8
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human NET expressed in MDCK-Net6 cells assessed as inhibition of norepinephrine uptake				J Med Chem 54: 6824-31 (2011) Article DOI: 10.1021/jm200733r BindingDB Entry DOI: 10.7270/Q2XD1227
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50264310 (1-methyl-5-(5-methyl-2-oxo-5-(thiophen-3-yl)-1,2,3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from progesterone receptor in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM35229 (3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...) Show SMILES CNCCCN1c2ccccc2CCc2ccccc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 18: 6067-70 (2008) Article DOI: 10.1016/j.bmcl.2008.10.026 BindingDB Entry DOI: 10.7270/Q2JD4XQT
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair

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