Compile Data Set for Download or QSAR

Found 75 hits with Last Name = 'tsujimoto' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342169 (CHEMBL1766170 | rac-1-(4'-Fluoro[1,1'-biphenyl]-3-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H19FN2O/c1-13(2)19(23,18-11-21-12-22-18)16-5-3-4-15(10-16)14-6-8-17(20)9-7-14/h3-13,23H,1-2H3,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342168 (CHEMBL1765101 | rac-1-(1H-Imidazol-4-yl)-1-(4'-met...) Show SMILES COc1ccc(cc1)-c1cccc(c1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C20H22N2O2/c1-14(2)20(23,19-12-21-13-22-19)17-6-4-5-16(11-17)15-7-9-18(24-3)10-8-15/h4-14,23H,1-3H3,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342186 ((S)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)-2-methyl...) Show SMILES CC(C)[C@@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-9-7-16(8-10-18)17-5-4-6-19(11-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)/t21-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342167 (CHEMBL1766169 | rac-1-[1,1'-biphenyl]-3-yl-1-(1H-i...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C19H20N2O/c1-14(2)19(22,18-12-20-13-21-18)17-10-6-9-16(11-17)15-7-4-3-5-8-15/h3-14,22H,1-2H3,(H,20,21)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342175 (CHEMBL1766176 | rac-N-{4-[1-Hydroxy-1-(1H-imidazol...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-9-7-16(8-10-18)17-5-4-6-19(11-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342167 (CHEMBL1766169 | rac-1-[1,1'-biphenyl]-3-yl-1-(1H-i...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C19H20N2O/c1-14(2)19(22,18-12-20-13-21-18)17-10-6-9-16(11-17)15-7-4-3-5-8-15/h3-14,22H,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342170 (CHEMBL1766171 | rac-1-(4'-Chloro[1,1'-biphenyl]-3-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c1-13(2)19(23,18-11-21-12-22-18)16-5-3-4-15(10-16)14-6-8-17(20)9-7-14/h3-13,23H,1-2H3,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342190 ((S)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)bi...) Show SMILES CC[C@@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C20H21N3O2/c1-3-20(25,19-12-21-13-22-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)23-14(2)24/h4-13,25H,3H2,1-2H3,(H,21,22)(H,23,24)/t20-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342169 (CHEMBL1766170 | rac-1-(4'-Fluoro[1,1'-biphenyl]-3-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H19FN2O/c1-13(2)19(23,18-11-21-12-22-18)16-5-3-4-15(10-16)14-6-8-17(20)9-7-14/h3-13,23H,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342179 (CHEMBL1766180 | rac-N-{4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CNC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C21H24N4O2/c1-14(2)21(27,19-12-23-13-24-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)25-20(26)22-3/h4-14,27H,1-3H3,(H,23,24)(H2,22,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342190 ((S)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)bi...) Show SMILES CC[C@@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C20H21N3O2/c1-3-20(25,19-12-21-13-22-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)23-14(2)24/h4-13,25H,3H2,1-2H3,(H,21,22)(H,23,24)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342176 (CHEMBL1766177 | rac-N-{4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-8-4-16(5-9-18)17-6-10-19(11-7-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342175 (CHEMBL1766176 | rac-N-{4-[1-Hydroxy-1-(1H-imidazol...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-9-7-16(8-10-18)17-5-4-6-19(11-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342179 (CHEMBL1766180 | rac-N-{4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CNC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C21H24N4O2/c1-14(2)21(27,19-12-23-13-24-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)25-20(26)22-3/h4-14,27H,1-3H3,(H,23,24)(H2,22,25,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342183 (CHEMBL1766184 | rac-N-[4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CCC(O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C20H21N3O2/c1-3-20(25,19-12-21-13-22-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)23-14(2)24/h4-13,25H,3H2,1-2H3,(H,21,22)(H,23,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342188 ((S)-N-(6-(4-(1-hydroxy-1-(1H-imidazol-4-yl)-2-meth...) Show SMILES CC(C)[C@@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)n1 |r| Show InChI InChI=1S/C20H22N4O2/c1-13(2)20(26,18-11-21-12-22-18)16-9-7-15(8-10-16)17-5-4-6-19(24-17)23-14(3)25/h4-13,26H,1-3H3,(H,21,22)(H,23,24,25)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342186 ((S)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)-2-methyl...) Show SMILES CC(C)[C@@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-9-7-16(8-10-18)17-5-4-6-19(11-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342173 (CHEMBL1766174 | rac-1-(4'-Fluoro[1,1'-biphenyl]-4-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H19FN2O/c1-13(2)19(23,18-11-21-12-22-18)16-7-3-14(4-8-16)15-5-9-17(20)10-6-15/h3-13,23H,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342174 (CHEMBL1766175 | rac-1-(4'-Chloro[1,1'-biphenyl]-4-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c1-13(2)19(23,18-11-21-12-22-18)16-7-3-14(4-8-16)15-5-9-17(20)10-6-15/h3-13,23H,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342173 (CHEMBL1766174 | rac-1-(4'-Fluoro[1,1'-biphenyl]-4-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H19FN2O/c1-13(2)19(23,18-11-21-12-22-18)16-7-3-14(4-8-16)15-5-9-17(20)10-6-15/h3-13,23H,1-2H3,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342174 (CHEMBL1766175 | rac-1-(4'-Chloro[1,1'-biphenyl]-4-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c1-13(2)19(23,18-11-21-12-22-18)16-7-3-14(4-8-16)15-5-9-17(20)10-6-15/h3-13,23H,1-2H3,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342171 (CHEMBL1766172 | rac-1-[1,1'-Biphenyl]-4-yl-1-(1H-i...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H20N2O/c1-14(2)19(22,18-12-20-13-21-18)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-14,22H,1-2H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342188 ((S)-N-(6-(4-(1-hydroxy-1-(1H-imidazol-4-yl)-2-meth...) Show SMILES CC(C)[C@@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)n1 |r| Show InChI InChI=1S/C20H22N4O2/c1-13(2)20(26,18-11-21-12-22-18)16-9-7-15(8-10-16)17-5-4-6-19(24-17)23-14(3)25/h4-13,26H,1-3H3,(H,21,22)(H,23,24,25)/t20-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342171 (CHEMBL1766172 | rac-1-[1,1'-Biphenyl]-4-yl-1-(1H-i...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H20N2O/c1-14(2)19(22,18-12-20-13-21-18)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-14,22H,1-2H3,(H,20,21)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342181 (CHEMBL1766182 | rac-N-{6-(4-[1-Hydroxy-1-(1H-imida...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)n1 Show InChI InChI=1S/C20H22N4O2/c1-13(2)20(26,18-11-21-12-22-18)16-9-7-15(8-10-16)17-5-4-6-19(24-17)23-14(3)25/h4-13,26H,1-3H3,(H,21,22)(H,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342182 (CHEMBL1766183 | rac-N-[4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(C)(O)c1cnc[nH]1 Show InChI InChI=1S/C19H19N3O2/c1-13(23)22-17-5-3-4-15(10-17)14-6-8-16(9-7-14)19(2,24)18-11-20-12-21-18/h3-12,24H,1-2H3,(H,20,21)(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342183 (CHEMBL1766184 | rac-N-[4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CCC(O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 Show InChI InChI=1S/C20H21N3O2/c1-3-20(25,19-12-21-13-22-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)23-14(2)24/h4-13,25H,3H2,1-2H3,(H,21,22)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342177 (CHEMBL1766178 | rac-4'-[1-Hydroxy1-(1H-imidazol-4-...) Show SMILES CNC(=O)c1cccc(c1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,19-12-23-13-24-19)18-9-7-15(8-10-18)16-5-4-6-17(11-16)20(25)22-3/h4-14,26H,1-3H3,(H,22,25)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342184 (CHEMBL1766185 | rac-N-[4'-[Cyclopropyl(hydroxy)-1H...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)(C1CC1)c1cnc[nH]1 Show InChI InChI=1S/C21H21N3O2/c1-14(25)24-19-4-2-3-16(11-19)15-5-7-17(8-6-15)21(26,18-9-10-18)20-12-22-13-23-20/h2-8,11-13,18,26H,9-10H2,1H3,(H,22,23)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342177 (CHEMBL1766178 | rac-4'-[1-Hydroxy1-(1H-imidazol-4-...) Show SMILES CNC(=O)c1cccc(c1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,19-12-23-13-24-19)18-9-7-15(8-10-18)16-5-4-6-17(11-16)20(25)22-3/h4-14,26H,1-3H3,(H,22,25)(H,23,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342170 (CHEMBL1766171 | rac-1-(4'-Chloro[1,1'-biphenyl]-3-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H19ClN2O/c1-13(2)19(23,18-11-21-12-22-18)16-5-3-4-15(10-16)14-6-8-17(20)9-7-14/h3-13,23H,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342181 (CHEMBL1766182 | rac-N-{6-(4-[1-Hydroxy-1-(1H-imida...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)n1 Show InChI InChI=1S/C20H22N4O2/c1-13(2)20(26,18-11-21-12-22-18)16-9-7-15(8-10-16)17-5-4-6-19(24-17)23-14(3)25/h4-13,26H,1-3H3,(H,21,22)(H,23,24,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342172 (CHEMBL1766173 | rac-1-(1H-Imidazol-4-yl)-1-(4'-met...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C20H22N2O2/c1-14(2)20(23,19-12-21-13-22-19)17-8-4-15(5-9-17)16-6-10-18(24-3)11-7-16/h4-14,23H,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342182 (CHEMBL1766183 | rac-N-[4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(C)(O)c1cnc[nH]1 Show InChI InChI=1S/C19H19N3O2/c1-13(23)22-17-5-3-4-15(10-17)14-6-8-16(9-7-14)19(2,24)18-11-20-12-21-18/h3-12,24H,1-2H3,(H,20,21)(H,22,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342178 (CHEMBL1766179 | rac-4'-[1-Hydroxy-1-(1H-imidazol-4...) Show SMILES CNS(=O)(=O)c1cccc(c1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C20H23N3O3S/c1-14(2)20(24,19-12-22-13-23-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)27(25,26)21-3/h4-14,21,24H,1-3H3,(H,22,23)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342185 (CHEMBL1766186 | rac-N-[4'-[1-Hydroxy(1H-imidazol-4...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)c1cnc[nH]1 Show InChI InChI=1S/C18H17N3O2/c1-12(22)21-16-4-2-3-15(9-16)13-5-7-14(8-6-13)18(23)17-10-19-11-20-17/h2-11,18,23H,1H3,(H,19,20)(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342184 (CHEMBL1766185 | rac-N-[4'-[Cyclopropyl(hydroxy)-1H...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)(C1CC1)c1cnc[nH]1 Show InChI InChI=1S/C21H21N3O2/c1-14(25)24-19-4-2-3-16(11-19)15-5-7-17(8-6-15)21(26,18-9-10-18)20-12-22-13-23-20/h2-8,11-13,18,26H,9-10H2,1H3,(H,22,23)(H,24,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342189 ((R)-N-(6-(4-(1-hydroxy-1-(1H-imidazol-4-yl)-2-meth...) Show SMILES CC(C)[C@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)n1 |r| Show InChI InChI=1S/C20H22N4O2/c1-13(2)20(26,18-11-21-12-22-18)16-9-7-15(8-10-16)17-5-4-6-19(24-17)23-14(3)25/h4-13,26H,1-3H3,(H,21,22)(H,23,24,25)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342172 (CHEMBL1766173 | rac-1-(1H-Imidazol-4-yl)-1-(4'-met...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C20H22N2O2/c1-14(2)20(23,19-12-21-13-22-19)17-8-4-15(5-9-17)16-6-10-18(24-3)11-7-16/h4-14,23H,1-3H3,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342176 (CHEMBL1766177 | rac-N-{4'-[1-Hydroxy-1-(1H-imidazo...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-8-4-16(5-9-18)17-6-10-19(11-7-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342168 (CHEMBL1765101 | rac-1-(1H-Imidazol-4-yl)-1-(4'-met...) Show SMILES COc1ccc(cc1)-c1cccc(c1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C20H22N2O2/c1-14(2)20(23,19-12-21-13-22-19)17-6-4-5-16(11-17)15-7-9-18(24-3)10-8-15/h4-14,23H,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342180 (CHEMBL1766181 | rac-1-(1H-Imidazol-4-yl)-2-methyl-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C18H19N3O/c1-13(2)18(22,17-11-19-12-21-17)15-8-6-14(7-9-15)16-5-3-4-10-20-16/h3-13,22H,1-2H3,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342178 (CHEMBL1766179 | rac-4'-[1-Hydroxy-1-(1H-imidazol-4...) Show SMILES CNS(=O)(=O)c1cccc(c1)-c1ccc(cc1)C(O)(C(C)C)c1cnc[nH]1 Show InChI InChI=1S/C20H23N3O3S/c1-14(2)20(24,19-12-22-13-23-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)27(25,26)21-3/h4-14,21,24H,1-3H3,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342180 (CHEMBL1766181 | rac-1-(1H-Imidazol-4-yl)-2-methyl-...) Show SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C18H19N3O/c1-13(2)18(22,17-11-19-12-21-17)15-8-6-14(7-9-15)16-5-3-4-10-20-16/h3-13,22H,1-2H3,(H,19,21)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342191 ((R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)bi...) Show SMILES CC[C@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C20H21N3O2/c1-3-20(25,19-12-21-13-22-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)23-14(2)24/h4-13,25H,3H2,1-2H3,(H,21,22)(H,23,24)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342185 (CHEMBL1766186 | rac-N-[4'-[1-Hydroxy(1H-imidazol-4...) Show SMILES CC(=O)Nc1cccc(c1)-c1ccc(cc1)C(O)c1cnc[nH]1 Show InChI InChI=1S/C18H17N3O2/c1-12(22)21-16-4-2-3-15(9-16)13-5-7-14(8-6-13)18(23)17-10-19-11-20-17/h2-11,18,23H,1H3,(H,19,20)(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50342187 ((R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)-2-methyl...) Show SMILES CC(C)[C@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-9-7-16(8-10-18)17-5-4-6-19(11-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of human 17,20 lyase activity				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342191 ((R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)propyl)bi...) Show SMILES CC[C@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C20H21N3O2/c1-3-20(25,19-12-21-13-22-19)17-9-7-15(8-10-17)16-5-4-6-18(11-16)23-14(2)24/h4-13,25H,3H2,1-2H3,(H,21,22)(H,23,24)/t20-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342187 ((R)-N-(4'-(1-hydroxy-1-(1H-imidazol-4-yl)-2-methyl...) Show SMILES CC(C)[C@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)c1 |r| Show InChI InChI=1S/C21H23N3O2/c1-14(2)21(26,20-12-22-13-23-20)18-9-7-16(8-10-18)17-5-4-6-19(11-17)24-15(3)25/h4-14,26H,1-3H3,(H,22,23)(H,24,25)/t21-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Rattus norvegicus (Rat))	BDBM50342189 ((R)-N-(6-(4-(1-hydroxy-1-(1H-imidazol-4-yl)-2-meth...) Show SMILES CC(C)[C@](O)(c1cnc[nH]1)c1ccc(cc1)-c1cccc(NC(C)=O)n1 |r| Show InChI InChI=1S/C20H22N4O2/c1-13(2)20(26,18-11-21-12-22-18)16-9-7-15(8-10-16)17-5-4-6-19(24-17)23-14(3)25/h4-13,26H,1-3H3,(H,21,22)(H,23,24,25)/t20-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company, Ltd Curated by ChEMBL					Assay Description Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomes				Bioorg Med Chem 19: 2428-42 (2011) Article DOI: 10.1016/j.bmc.2011.02.009 BindingDB Entry DOI: 10.7270/Q2FJ2H3G
					More data for this Ligand-Target Pair

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