Compile Data Set for Download or QSAR

Found 908 hits with Last Name = 'vyskocil' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50339608 (3-(1-Amino-1-methylethyl)-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CC(C)(N)c1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-28(2,33)19-11-18(12-20(15-19)29(30,31)32)27(38)35-21-5-3-16-4-6-22(14-17(16)13-21)39-24-9-10-34-26-23(24)7-8-25(37)36-26/h4,6,9-12,14-15,21H,3,5,7-8,13,33H2,1-2H3,(H,35,38)(H,34,36,37)/t21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of RET				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50339609 (3-[(Dimethylamino)methyl]-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CN(C)Cc1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-36(2)16-17-11-20(13-21(12-17)29(30,31)32)28(38)34-22-5-3-18-4-6-23(15-19(18)14-22)39-25-9-10-33-27-24(25)7-8-26(37)35-27/h4,6,9-13,15,22H,3,5,7-8,14,16H2,1-2H3,(H,34,38)(H,33,35,37)/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Abl1				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50339609 (3-[(Dimethylamino)methyl]-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CN(C)Cc1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-36(2)16-17-11-20(13-21(12-17)29(30,31)32)28(38)34-22-5-3-18-4-6-23(15-19(18)14-22)39-25-9-10-33-27-24(25)7-8-26(37)35-27/h4,6,9-13,15,22H,3,5,7-8,14,16H2,1-2H3,(H,34,38)(H,33,35,37)/t22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of RET				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339609 (3-[(Dimethylamino)methyl]-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CN(C)Cc1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-36(2)16-17-11-20(13-21(12-17)29(30,31)32)28(38)34-22-5-3-18-4-6-23(15-19(18)14-22)39-25-9-10-33-27-24(25)7-8-26(37)35-27/h4,6,9-13,15,22H,3,5,7-8,14,16H2,1-2H3,(H,34,38)(H,33,35,37)/t22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339608 (3-(1-Amino-1-methylethyl)-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CC(C)(N)c1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-28(2,33)19-11-18(12-20(15-19)29(30,31)32)27(38)35-21-5-3-16-4-6-22(14-17(16)13-21)39-24-9-10-34-26-23(24)7-8-25(37)36-26/h4,6,9-12,14-15,21H,3,5,7-8,13,33H2,1-2H3,(H,35,38)(H,34,36,37)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50339609 (3-[(Dimethylamino)methyl]-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CN(C)Cc1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-36(2)16-17-11-20(13-21(12-17)29(30,31)32)28(38)34-22-5-3-18-4-6-23(15-19(18)14-22)39-25-9-10-33-27-24(25)7-8-26(37)35-27/h4,6,9-13,15,22H,3,5,7-8,14,16H2,1-2H3,(H,34,38)(H,33,35,37)/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of DDR2				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339615 ((2S)-7-({2-[(Cyclopropylcarbonyl)amino]pyridin-4-y...) Show SMILES CN(C)Cc1cc(NC(=O)[C@H]2CCc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cc3C2)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C30H31F3N4O3/c1-37(2)17-18-11-23(30(31,32)33)15-24(12-18)35-29(39)21-6-3-19-7-8-25(14-22(19)13-21)40-26-9-10-34-27(16-26)36-28(38)20-4-5-20/h7-12,14-16,20-21H,3-6,13,17H2,1-2H3,(H,35,39)(H,34,36,38)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as reduction in [33P]ATP incorporation into biotinylated substrate peptide after 3 hrs by flash plate assay				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50339608 (3-(1-Amino-1-methylethyl)-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CC(C)(N)c1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-28(2,33)19-11-18(12-20(15-19)29(30,31)32)27(38)35-21-5-3-16-4-6-22(14-17(16)13-21)39-24-9-10-34-26-23(24)7-8-25(37)36-26/h4,6,9-12,14-15,21H,3,5,7-8,13,33H2,1-2H3,(H,35,38)(H,34,36,37)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of wild-type B-Raf				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339613 ((2S)-N-[3-(aminomethyl)-5-(trifluoromethyl)phenyl]...) Show SMILES NCc1cc(NC(=O)[C@H]2CCc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cc3C2)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C28H27F3N4O3/c29-28(30,31)21-9-16(15-32)10-22(13-21)34-27(37)19-4-1-17-5-6-23(12-20(17)11-19)38-24-7-8-33-25(14-24)35-26(36)18-2-3-18/h5-10,12-14,18-19H,1-4,11,15,32H2,(H,34,37)(H,33,35,36)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as reduction in [33P]ATP incorporation into biotinylated substrate peptide after 3 hrs by flash plate assay				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339616 (7-({2-[(Cyclopropylcarbonyl)amino]pyridin-4-yl}oxy...) Show SMILES CC(C)NCc1cc(NC(=O)C2CCc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cc3C2)cc(c1)C(F)(F)F Show InChI InChI=1S/C31H33F3N4O3/c1-18(2)36-17-19-11-24(31(32,33)34)15-25(12-19)37-30(40)22-6-3-20-7-8-26(14-23(20)13-22)41-27-9-10-35-28(16-27)38-29(39)21-4-5-21/h7-12,14-16,18,21-22,36H,3-6,13,17H2,1-2H3,(H,37,40)(H,35,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as reduction in [33P]ATP incorporation into biotinylated substrate peptide after 3 hrs by flash plate assay				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50339609 (3-[(Dimethylamino)methyl]-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CN(C)Cc1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-36(2)16-17-11-20(13-21(12-17)29(30,31)32)28(38)34-22-5-3-18-4-6-23(15-19(18)14-22)39-25-9-10-33-27-24(25)7-8-26(37)35-27/h4,6,9-13,15,22H,3,5,7-8,14,16H2,1-2H3,(H,34,38)(H,33,35,37)/t22-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of wild-type B-Raf				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM16673 (4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...) Show SMILES CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1 Show InChI InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339611 ((2S)-7-{[2-(acetylamino)pyridin-4-yl]oxy}-N-[3-(am...) Show SMILES CC(=O)Nc1cc(Oc2ccc3CC[C@@H](Cc3c2)C(=O)Nc2cc(CN)cc(c2)C(F)(F)F)ccn1 |r| Show InChI InChI=1S/C26H25F3N4O3/c1-15(34)32-24-13-23(6-7-31-24)36-22-5-4-17-2-3-18(10-19(17)11-22)25(35)33-21-9-16(14-30)8-20(12-21)26(27,28)29/h4-9,11-13,18H,2-3,10,14,30H2,1H3,(H,33,35)(H,31,32,34)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as reduction in [33P]ATP incorporation into biotinylated substrate peptide after 3 hrs by flash plate assay				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339614 ((2R)-N-[3-(aminomethyl)-5-(trifluoromethyl)phenyl]...) Show SMILES NCc1cc(NC(=O)[C@@H]2CCc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cc3C2)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C28H27F3N4O3/c29-28(30,31)21-9-16(15-32)10-22(13-21)34-27(37)19-4-1-17-5-6-23(12-20(17)11-19)38-24-7-8-33-25(14-24)35-26(36)18-2-3-18/h5-10,12-14,18-19H,1-4,11,15,32H2,(H,34,37)(H,33,35,36)/t19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as reduction in [33P]ATP incorporation into biotinylated substrate peptide after 3 hrs by flash plate assay				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50339608 (3-(1-Amino-1-methylethyl)-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CC(C)(N)c1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-28(2,33)19-11-18(12-20(15-19)29(30,31)32)27(38)35-21-5-3-16-4-6-22(14-17(16)13-21)39-24-9-10-34-26-23(24)7-8-25(37)36-26/h4,6,9-12,14-15,21H,3,5,7-8,13,33H2,1-2H3,(H,35,38)(H,34,36,37)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339612 (CHEMBL1688868 | N-[3-(Aminomethyl)-5-(trifluoromet...) Show SMILES NCc1cc(NC(=O)C2CCc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cc3C2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H27F3N4O3/c29-28(30,31)21-9-16(15-32)10-22(13-21)34-27(37)19-4-1-17-5-6-23(12-20(17)11-19)38-24-7-8-33-25(14-24)35-26(36)18-2-3-18/h5-10,12-14,18-19H,1-4,11,15,32H2,(H,34,37)(H,33,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as reduction in [33P]ATP incorporation into biotinylated substrate peptide after 3 hrs by flash plate assay				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50339608 (3-(1-Amino-1-methylethyl)-N-{(2R)-7-[(7-oxo-5,6,7,...) Show SMILES CC(C)(N)c1cc(cc(c1)C(F)(F)F)C(=O)N[C@@H]1CCc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 |r| Show InChI InChI=1S/C29H29F3N4O3/c1-28(2,33)19-11-18(12-20(15-19)29(30,31)32)27(38)35-21-5-3-16-4-6-22(14-17(16)13-21)39-24-9-10-34-26-23(24)7-8-25(37)36-26/h4,6,9-12,14-15,21H,3,5,7-8,13,33H2,1-2H3,(H,35,38)(H,34,36,37)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of DDR2				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50339623 (4-[3-(3-{[4-Chloro-3-(trifluoromethyl)phenyl]amino...) Show SMILES CNC(=O)c1cc(Oc2cccc(CCC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2)ccn1 Show InChI InChI=1S/C23H19ClF3N3O3/c1-28-22(32)20-13-17(9-10-29-20)33-16-4-2-3-14(11-16)5-8-21(31)30-15-6-7-19(24)18(12-15)23(25,26)27/h2-4,6-7,9-13H,5,8H2,1H3,(H,28,32)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as reduction in [33P]ATP incorporation into biotinylated substrate peptide after 3 hrs by flash plate assay				J Med Chem 54: 1836-46 (2011) Article DOI: 10.1021/jm101479y BindingDB Entry DOI: 10.7270/Q2DB824F
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398449 (US10323018, Compound I-178) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2n1C)-c1ccc(F)cc1 Show InChI InChI=1S/C26H22FN5O2/c1-3-34-24-13-20(16-4-7-18(27)8-5-16)30-21-12-17(6-9-19(21)24)26(33)29-15-25-31-22-14-28-11-10-23(22)32(25)2/h4-14H,3,15H2,1-2H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398458 (US10323018, Compound I-187) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1cc(F)ccc1OC Show InChI InChI=1S/C26H22FN5O3/c1-3-35-24-12-21(18-11-16(27)5-7-23(18)34-2)30-20-10-15(4-6-17(20)24)26(33)29-14-25-31-19-8-9-28-13-22(19)32-25/h4-13H,3,14H2,1-2H3,(H,29,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398459 (US10323018, Compound I-188) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1cc(OC)ncc1F Show InChI InChI=1S/C25H21FN6O3/c1-3-35-22-10-20(16-9-24(34-2)28-11-17(16)26)30-19-8-14(4-5-15(19)22)25(33)29-13-23-31-18-6-7-27-12-21(18)32-23/h4-12H,3,13H2,1-2H3,(H,29,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398463 (US10323018, Compound I-192) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2ccncc2[nH]1)-c1cccnc1OC Show InChI InChI=1S/C25H22N6O3/c1-3-34-22-12-20(17-5-4-9-27-25(17)33-2)29-19-11-15(6-7-16(19)22)24(32)28-14-23-30-18-8-10-26-13-21(18)31-23/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398464 (US10323018, Compound I-193) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(OC)nc1 Show InChI InChI=1S/C25H22N6O3/c1-3-34-22-11-19(16-5-7-24(33-2)27-12-16)29-20-10-15(4-6-17(20)22)25(32)28-14-23-30-18-8-9-26-13-21(18)31-23/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398465 (US10323018, Compound I-194) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccnc(OC)c1 Show InChI InChI=1S/C25H22N6O3/c1-3-34-22-12-19(15-6-9-27-24(11-15)33-2)29-20-10-16(4-5-17(20)22)25(32)28-14-23-30-18-7-8-26-13-21(18)31-23/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398467 (US10323018, Compound I-196) Show SMILES COc1cc(ccn1)-c1nc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H23FN6O2/c1-36-24-16-18(10-12-31-24)25-21-9-6-19(27(35)32-11-2-3-23-29-13-14-30-23)15-22(21)33-26(34-25)17-4-7-20(28)8-5-17/h4-10,12-16H,2-3,11H2,1H3,(H,29,30)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398469 (US10323018, Compound I-198) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H22ClN5O2/c1-2-31-21-13-19(15-5-8-17(24)9-6-15)28-20-12-16(7-10-18(20)21)23(30)25-11-3-4-22-26-14-27-29-22/h5-10,12-14H,2-4,11H2,1H3,(H,25,30)(H,26,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398472 (US10323018, Compound I-201) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1c[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O2/c1-3-32-24-14-22(17-6-9-20(26)10-7-17)29-23-13-18(8-11-21(23)24)25(31)27-12-4-5-19-15-28-30-16(19)2/h6-11,13-15H,3-5,12H2,1-2H3,(H,27,31)(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398474 (US10323018, Compound I-203) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1n[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN5O2/c1-3-31-22-13-20(15-4-7-17(24)8-5-15)26-21-12-16(6-9-18(21)22)23(30)25-11-10-19-14(2)27-29-28-19/h4-9,12-13H,3,10-11H2,1-2H3,(H,25,30)(H,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398475 (US10323018, Compound I-204) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cc[nH]n1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-2-31-23-15-21(16-5-8-18(25)9-6-16)28-22-14-17(7-10-20(22)23)24(30)26-12-3-4-19-11-13-27-29-19/h5-11,13-15H,2-4,12H2,1H3,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398495 (US10323018, Compound I-224) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cncn1C)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O2/c1-3-32-24-14-22(17-6-9-19(26)10-7-17)29-23-13-18(8-11-21(23)24)25(31)28-12-4-5-20-15-27-16-30(20)2/h6-11,13-16H,3-5,12H2,1-2H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398498 (US10323018, Compound I-227) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ccc(C)nc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H26FN3O2/c1-3-33-26-16-24(20-8-11-22(28)12-9-20)31-25-15-21(10-13-23(25)26)27(32)29-14-4-5-19-7-6-18(2)30-17-19/h6-13,15-17H,3-5,14H2,1-2H3,(H,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398499 (US10323018, Compound I-228) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cncnc1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H23FN4O2/c1-2-32-24-13-22(18-5-8-20(26)9-6-18)30-23-12-19(7-10-21(23)24)25(31)29-11-3-4-17-14-27-16-28-15-17/h5-10,12-16H,2-4,11H2,1H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398500 (US10323018, Compound I-229) Show SMILES OCCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O3/c25-18-6-3-16(4-7-18)20-15-22(32-13-12-30)19-8-5-17(14-21(19)29-20)24(31)28-9-1-2-23-26-10-11-27-23/h3-8,10-11,14-15,30H,1-2,9,12-13H2,(H,26,27)(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398378 (US10323018, Compound I-107) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1cnn[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H20FN5O2/c1-2-30-21-12-19(14-3-6-16(23)7-4-14)26-20-11-15(5-8-18(20)21)22(29)24-10-9-17-13-25-28-27-17/h3-8,11-13H,2,9-10H2,1H3,(H,24,29)(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398381 (US10323018, Compound I-110) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(C)nc1 Show InChI InChI=1S/C23H24N6O2/c1-3-31-22-12-20(17-7-6-15(2)25-13-17)27-21-11-16(8-9-19(21)22)23(30)24-10-4-5-18-14-26-29-28-18/h6-9,11-14H,3-5,10H2,1-2H3,(H,24,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398386 (US10323018, Compound I-115) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H22FN5O2/c1-2-31-22-13-20(15-5-8-17(24)9-6-15)27-21-12-16(7-10-19(21)22)23(30)25-11-3-4-18-14-26-29-28-18/h5-10,12-14H,2-4,11H2,1H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398387 (US10323018, Compound I-116) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccnc(OC)c1 Show InChI InChI=1S/C23H24N6O3/c1-3-32-21-13-19(15-8-10-24-22(12-15)31-2)27-20-11-16(6-7-18(20)21)23(30)25-9-4-5-17-14-26-29-28-17/h6-8,10-14H,3-5,9H2,1-2H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398388 (US10323018, Compound I-117) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccnc(C)c1 Show InChI InChI=1S/C23H24N6O2/c1-3-31-22-13-20(16-8-10-24-15(2)11-16)27-21-12-17(6-7-19(21)22)23(30)25-9-4-5-18-14-26-29-28-18/h6-8,10-14H,3-5,9H2,1-2H3,(H,25,30)(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398392 (US10323018, Compound I-121) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1cnn[nH]1)-c1ccc(F)cc1OC Show InChI InChI=1S/C24H24FN5O3/c1-3-33-23-13-21(18-9-7-16(25)12-22(18)32-2)28-20-11-15(6-8-19(20)23)24(31)26-10-4-5-17-14-27-30-29-17/h6-9,11-14H,3-5,10H2,1-2H3,(H,26,31)(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398396 (US10323018, Compound I-125) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1ccc(Cl)s1 Show InChI InChI=1S/C21H20ClN5O2S/c1-2-29-17-11-16(18-7-8-19(22)30-18)26-15-10-13(5-6-14(15)17)21(28)23-9-3-4-20-24-12-25-27-20/h5-8,10-12H,2-4,9H2,1H3,(H,23,28)(H,24,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398401 (US10323018, Compound I-130) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1ccn2ncnc2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H20FN5O2/c1-2-33-23-13-21(17-3-6-19(26)7-4-17)30-22-12-18(5-8-20(22)23)25(32)27-14-16-9-10-31-24(11-16)28-15-29-31/h3-13,15H,2,14H2,1H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398403 (US10323018, Compound I-132) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCc1c[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C24H23FN4O2/c1-3-31-23-13-21(16-4-7-19(25)8-5-16)28-22-12-17(6-9-20(22)23)24(30)26-11-10-18-14-27-29-15(18)2/h4-9,12-14H,3,10-11H2,1-2H3,(H,26,30)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398404 (US10323018, Compound I-133) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1n[nH]nc1C)-c1ccc(F)cc1 Show InChI InChI=1S/C24H24FN5O2/c1-3-32-23-14-21(16-6-9-18(25)10-7-16)27-22-13-17(8-11-19(22)23)24(31)26-12-4-5-20-15(2)28-30-29-20/h6-11,13-14H,3-5,12H2,1-2H3,(H,26,31)(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398407 (US10323018, Compound I-136) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1cc(C)nc(OC)c1 Show InChI InChI=1S/C24H26N6O3/c1-4-33-21-13-19(17-10-15(2)28-23(12-17)32-3)29-20-11-16(7-8-18(20)21)24(31)25-9-5-6-22-26-14-27-30-22/h7-8,10-14H,4-6,9H2,1-3H3,(H,25,31)(H,26,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398419 (US10323018, Compound I-148) Show SMILES Fc1ccc(cc1)-c1cc(-n2ccnc2)c2ccc(cc2n1)C(=O)NCCCc1nnc[nH]1 Show InChI InChI=1S/C24H20FN7O/c25-18-6-3-16(4-7-18)20-13-22(32-11-10-26-15-32)19-8-5-17(12-21(19)30-20)24(33)27-9-1-2-23-28-14-29-31-23/h3-8,10-15H,1-2,9H2,(H,27,33)(H,28,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398427 (US10323018, Compound I-156) Show SMILES COCCOc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O3/c1-32-13-14-33-23-16-21(17-4-7-19(26)8-5-17)30-22-15-18(6-9-20(22)23)25(31)29-10-2-3-24-27-11-12-28-24/h4-9,11-12,15-16H,2-3,10,13-14H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398434 (US10323018, Compound I-163) Show SMILES CCCc1cc(nc2cc(ccc12)C(=O)NCCCc1ncc[nH]1)-c1ccc(F)cc1 Show InChI InChI=1S/C25H25FN4O/c1-2-4-18-15-22(17-6-9-20(26)10-7-17)30-23-16-19(8-11-21(18)23)25(31)29-12-3-5-24-27-13-14-28-24/h6-11,13-16H,2-5,12H2,1H3,(H,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398435 (US10323018, Compound I-164) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCCCc1nnc[nH]1)-c1cc(OC)ncc1Cl Show InChI InChI=1S/C23H23ClN6O3/c1-3-33-20-11-19(16-10-22(32-2)26-12-17(16)24)29-18-9-14(6-7-15(18)20)23(31)25-8-4-5-21-27-13-28-30-21/h6-7,9-13H,3-5,8H2,1-2H3,(H,25,31)(H,27,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398438 (US10323018, Compound I-167) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(C)nc1 Show InChI InChI=1S/C25H22N6O2/c1-3-33-23-11-20(17-5-4-15(2)27-12-17)29-21-10-16(6-7-18(21)23)25(32)28-14-24-30-19-8-9-26-13-22(19)31-24/h4-13H,3,14H2,1-2H3,(H,28,32)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM398445 (US10323018, Compound I-174) Show SMILES CCOc1cc(nc2cc(ccc12)C(=O)NCc1nc2cnccc2[nH]1)-c1ccc(C)nc1OC Show InChI InChI=1S/C26H24N6O3/c1-4-35-23-12-21(18-7-5-15(2)29-26(18)34-3)30-20-11-16(6-8-17(20)23)25(33)28-14-24-31-19-9-10-27-13-22(19)32-24/h5-13H,4,14H2,1-3H3,(H,28,33)(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description To measure the inhibition of NAMPT activity hNAMPT protein stock and anti 6His-Tb (Cisbio; Cat. No. 61HISTLB) is diluted to 3× final concentration wi...				Bioorg Med Chem Lett 19: 5225-8 (2009) BindingDB Entry DOI: 10.7270/Q2Z60RF9
					More data for this Ligand-Target Pair

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