Found 330 hits with Last Name = 'wilson' and Initial = 'aw' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259548
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259611
(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati... |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50259611
(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | PDB
UniProtKB/SwissProt
antibodypedia
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CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of TP receptor |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259613
(CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl3NO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 25.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati... |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50183182
(2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-...)Show SMILES OC(=O)c1cccc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1 Show InChI InChI=1S/C26H19ClO3/c27-21-13-14-25(30-17-18-7-2-1-3-8-18)24(16-21)23-12-5-4-11-22(23)19-9-6-10-20(15-19)26(28)29/h1-16H,17H2,(H,28,29) | KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 31.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at EP1 receptor assessed as calcium mobilization by FLIPR assay |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461458
(CHEMBL4229200)Show SMILES CCOc1c2C(=O)N(C(=O)c2c(OCC)c2ncccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C23H20N2O6/c1-3-30-20-15-6-5-11-24-19(15)21(31-4-2)18-17(20)22(28)25(23(18)29)14-9-7-13(8-10-14)12-16(26)27/h5-11H,3-4,12H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461462
(CHEMBL4225786)Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C24H23NO5/c1-3-29-22-17-7-5-6-8-18(17)23(30-4-2)21-19(22)14-25(24(21)28)16-11-9-15(10-12-16)13-20(26)27/h5-12H,3-4,13-14H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259612
(CHEMBL513491 | sodium 6-(5-chloro-2-(2-chloro-4-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-5-7-19(27-11-12-4-6-15(23)10-17(12)22)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati... |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461457
(CHEMBL4225963)Show SMILES CCOc1c2C(=O)N(C(=O)c2c(OCC)c2cc(C)ccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C25H23NO6/c1-4-31-22-17-11-6-14(3)12-18(17)23(32-5-2)21-20(22)24(29)26(25(21)30)16-9-7-15(8-10-16)13-19(27)28/h6-12H,4-5,13H2,1-3H3,(H,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461454
(CHEMBL4224936)Show SMILES CCOc1c2C(=O)N(C(=O)c2c(OCC)c2ccccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C24H21NO6/c1-3-30-21-16-7-5-6-8-17(16)22(31-4-2)20-19(21)23(28)25(24(20)29)15-11-9-14(10-12-15)13-18(26)27/h5-12H,3-4,13H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461450
(CHEMBL4226720)Show SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(cc1)C(C)C(O)=O Show InChI InChI=1S/C25H25NO5/c1-4-30-22-18-8-6-7-9-19(18)23(31-5-2)21-20(22)14-26(24(21)27)17-12-10-16(11-13-17)15(3)25(28)29/h6-13,15H,4-5,14H2,1-3H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50259548
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to TP receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461451
(CHEMBL4226523)Show SMILES CC(C)Oc1c2CN(C(=O)c2c(OC(C)C)c2ccccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C26H27NO5/c1-15(2)31-24-19-7-5-6-8-20(19)25(32-16(3)4)23-21(24)14-27(26(23)30)18-11-9-17(10-12-18)13-22(28)29/h5-12,15-16H,13-14H2,1-4H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461453
(CHEMBL4226984)Show SMILES CCOc1c2CN(Cc2c(OCC)c2ccccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C24H25NO4/c1-3-28-23-18-7-5-6-8-19(18)24(29-4-2)21-15-25(14-20(21)23)17-11-9-16(10-12-17)13-22(26)27/h5-12H,3-4,13-15H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461463
(CHEMBL4225442)Show SMILES CCCOc1c2CN(C(=O)c2c(OCCC)c2ccccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C26H27NO5/c1-3-13-31-24-19-7-5-6-8-20(19)25(32-14-4-2)23-21(24)16-27(26(23)30)18-11-9-17(10-12-18)15-22(28)29/h5-12H,3-4,13-16H2,1-2H3,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461468
(CHEMBL4227243)Show SMILES CCCCOc1c2CN(C(=O)c2c(OCCCC)c2ccccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C28H31NO5/c1-3-5-15-33-26-21-9-7-8-10-22(21)27(34-16-6-4-2)25-23(26)18-29(28(25)32)20-13-11-19(12-14-20)17-24(30)31/h7-14H,3-6,15-18H2,1-2H3,(H,30,31) | PDB
Reactome pathway
KEGG
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| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human)) | BDBM50259548
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 | PDB
KEGG
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CHEMBL
PC cid
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UniChem
Similars
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Activity at EP3 receptor by FLIPR method |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50461456
(CHEMBL4228095)Show SMILES CCCCCCOc1c2CN(C(=O)c2c(OCCCCCC)c2ccccc12)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C32H39NO5/c1-3-5-7-11-19-37-30-25-13-9-10-14-26(25)31(38-20-12-8-6-4-2)29-27(30)22-33(32(29)36)24-17-15-23(16-18-24)21-28(34)35/h9-10,13-18H,3-8,11-12,19-22H2,1-2H3,(H,34,35) | PDB
Reactome pathway
KEGG
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AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| <6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK 293 (EBNA) cell membranes incubated for 60 mins by scintillation counting method |
Bioorg Med Chem Lett 28: 1892-1896 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.091
BindingDB Entry DOI: 10.7270/Q21Z472W |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50414022
(CHEMBL2110364 | GSK-180100B)Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccc(Cl)cc1Cl)C([O-])=O Show InChI InChI=1S/C19H15BrCl2N2O3/c1-11-6-17(19(25)26)23-24(11)9-13-7-14(20)3-5-18(13)27-10-12-2-4-15(21)8-16(12)22/h2-8H,9-10H2,1H3,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
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CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.129 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413672
(CHEMBL516324)Show SMILES CCCC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H26ClNO4/c1-2-8-29(33)32-24-16-21(15-22(17-24)30(34)35)25-11-6-7-12-26(25)27-18-23(31)13-14-28(27)36-19-20-9-4-3-5-10-20/h3-7,9-18H,2,8,19H2,1H3,(H,32,33)(H,34,35) | KEGG
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UniChem
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PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50197898
(6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...)Show SMILES OC(=O)c1cccc(n1)C1=C(CCC1)c1cc(Cl)ccc1OCc1ccc(F)cc1F |t:10| Show InChI InChI=1S/C24H18ClF2NO3/c25-15-8-10-23(31-13-14-7-9-16(26)12-20(14)27)19(11-15)17-3-1-4-18(17)21-5-2-6-22(28-21)24(29)30/h2,5-12H,1,3-4,13H2,(H,29,30) | KEGG
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PubMed
| n/a | n/a | 2.51 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413667
(CHEMBL514574)Show SMILES OC(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccc(F)cc1F Show InChI InChI=1S/C25H16ClF2NO3/c26-16-9-11-24(32-14-15-8-10-17(27)13-21(15)28)20(12-16)18-4-1-2-5-19(18)22-6-3-7-23(29-22)25(30)31/h1-13H,14H2,(H,30,31) | KEGG
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UniChem
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PubMed
| n/a | n/a | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413670
(CHEMBL458452)Show SMILES COCC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C29H24ClNO5/c1-35-18-28(32)31-23-14-20(13-21(15-23)29(33)34)24-9-5-6-10-25(24)26-16-22(30)11-12-27(26)36-17-19-7-3-2-4-8-19/h2-16H,17-18H2,1H3,(H,31,32)(H,33,34) | KEGG
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413668
(CHEMBL457142)Show SMILES OC(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccc(F)cc1 Show InChI InChI=1S/C25H17ClFNO3/c26-17-10-13-24(31-15-16-8-11-18(27)12-9-16)21(14-17)19-4-1-2-5-20(19)22-6-3-7-23(28-22)25(29)30/h1-14H,15H2,(H,29,30) | KEGG
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413673
(CHEMBL456496)Show SMILES CCC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C29H24ClNO4/c1-2-28(32)31-23-15-20(14-21(16-23)29(33)34)24-10-6-7-11-25(24)26-17-22(30)12-13-27(26)35-18-19-8-4-3-5-9-19/h3-17H,2,18H2,1H3,(H,31,32)(H,33,34) | KEGG
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UniChem
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PubMed
| n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413669
(CHEMBL515981)Show SMILES OC(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1 Show InChI InChI=1S/C25H18ClNO3/c26-18-13-14-24(30-16-17-7-2-1-3-8-17)21(15-18)19-9-4-5-10-20(19)22-11-6-12-23(27-22)25(28)29/h1-15H,16H2,(H,28,29) | KEGG
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UniChem
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| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413674
(CHEMBL456495)Show SMILES CC(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C28H22ClNO4/c1-18(31)30-23-14-20(13-21(15-23)28(32)33)24-9-5-6-10-25(24)26-16-22(29)11-12-27(26)34-17-19-7-3-2-4-8-19/h2-16H,17H2,1H3,(H,30,31)(H,32,33) | KEGG
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| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50197899
(5-(2-(2-(benzyloxy)-5-(trifluoromethyl)phenyl)cycl...)Show SMILES OC(=O)c1cncc(c1)C1=C(CCC1)c1cc(ccc1OCc1ccccc1)C(F)(F)F |t:10| Show InChI InChI=1S/C25H20F3NO3/c26-25(27,28)19-9-10-23(32-15-16-5-2-1-3-6-16)22(12-19)21-8-4-7-20(21)17-11-18(24(30)31)14-29-13-17/h1-3,5-6,9-14H,4,7-8,15H2,(H,30,31) | KEGG
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UniChem
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PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413671
(CHEMBL458448)Show SMILES CC(C)C(=O)Nc1cc(cc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1)C(O)=O Show InChI InChI=1S/C30H26ClNO4/c1-19(2)29(33)32-24-15-21(14-22(16-24)30(34)35)25-10-6-7-11-26(25)27-17-23(31)12-13-28(27)36-18-20-8-4-3-5-9-20/h3-17,19H,18H2,1-2H3,(H,32,33)(H,34,35) | KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259613
(CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl3NO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
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UniChem
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PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413663
(CHEMBL466549)Show SMILES [O-]C(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1c(F)cc(F)cc1F Show InChI InChI=1S/C25H15ClF3NO3/c26-14-8-9-24(33-13-19-20(28)11-15(27)12-21(19)29)18(10-14)16-4-1-2-5-17(16)22-6-3-7-23(30-22)25(31)32/h1-12H,13H2,(H,31,32)/p-1 | KEGG
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UniChem
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PubMed
| n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259612
(CHEMBL513491 | sodium 6-(5-chloro-2-(2-chloro-4-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-5-7-19(27-11-12-4-6-15(23)10-17(12)22)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259611
(CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
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PubMed
| n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Rattus norvegicus (Rat)) | BDBM50259548
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 | Reactome pathway
KEGG
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| n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to rat EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259548
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 | KEGG
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| n/a | n/a | 15.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259548
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 | KEGG
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| n/a | n/a | 15.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50259548
(6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...)Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1 | KEGG
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| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to human EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413679
(CHEMBL456707)Show SMILES OC(=O)c1ccccc1-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1 Show InChI InChI=1S/C26H19ClO3/c27-19-14-15-25(30-17-18-8-2-1-3-9-18)24(16-19)22-12-5-4-10-20(22)21-11-6-7-13-23(21)26(28)29/h1-16H,17H2,(H,28,29) | KEGG
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UniChem
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| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413685
(CHEMBL516787)Show SMILES OC(=O)c1cccc(c1)-c1ccccc1-c1ccccc1OCc1ccccc1 Show InChI InChI=1S/C26H20O3/c27-26(28)21-12-8-11-20(17-21)22-13-4-5-14-23(22)24-15-6-7-16-25(24)29-18-19-9-2-1-3-10-19/h1-17H,18H2,(H,27,28) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413664
(CHEMBL467579)Show SMILES [O-]C(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccc(Cl)cc1F Show InChI InChI=1S/C25H16Cl2FNO3/c26-16-10-11-24(32-14-15-8-9-17(27)13-21(15)28)20(12-16)18-4-1-2-5-19(18)22-6-3-7-23(29-22)25(30)31/h1-13H,14H2,(H,30,31)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19.9 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50414026
(CHEMBL466101)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2F)n1 Show InChI InChI=1S/C20H14ClF2NO3/c21-14-5-7-19(27-11-12-4-6-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50414032
(CHEMBL511252)Show InChI InChI=1S/C19H20ClNO3/c20-15-8-9-18(24-12-13-4-1-2-5-13)14(10-15)11-16-6-3-7-17(21-16)19(22)23/h3,6-10,13H,1-2,4-5,11-12H2,(H,22,23)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50414029
(CHEMBL467113)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2)n1 Show InChI InChI=1S/C20H15Cl2NO3/c21-15-6-4-13(5-7-15)12-26-19-9-8-16(22)10-14(19)11-17-2-1-3-18(23-17)20(24)25/h1-10H,11-12H2,(H,24,25)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50414028
(CHEMBL466103)Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2Cl)n1 Show InChI InChI=1S/C20H15Cl2NO3/c21-15-8-9-19(26-12-13-4-1-2-6-17(13)22)14(10-15)11-16-5-3-7-18(23-16)20(24)25/h1-10H,11-12H2,(H,24,25)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413662
(CHEMBL459537)Show SMILES [O-]C(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1F Show InChI InChI=1S/C25H17ClFNO3/c26-17-12-13-24(31-15-16-6-1-4-9-21(16)27)20(14-17)18-7-2-3-8-19(18)22-10-5-11-23(28-22)25(29)30/h1-14H,15H2,(H,29,30)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50414030
(CHEMBL257998)Show InChI InChI=1S/C17H18ClNO3/c1-11(2)10-22-16-7-6-13(18)8-12(16)9-14-4-3-5-15(19-14)17(20)21/h3-8,11H,9-10H2,1-2H3,(H,20,21)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells |
Bioorg Med Chem Lett 19: 2599-603 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.112
BindingDB Entry DOI: 10.7270/Q2HT2P68 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413665
(CHEMBL467578)Show SMILES [O-]C(=O)c1cccc(n1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccc(Br)cc1F Show InChI InChI=1S/C25H16BrClFNO3/c26-16-9-8-15(21(28)12-16)14-32-24-11-10-17(27)13-20(24)18-4-1-2-5-19(18)22-6-3-7-23(29-22)25(30)31/h1-13H,14H2,(H,30,31)/p-1 | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50183182
(2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-...)Show SMILES OC(=O)c1cccc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1 Show InChI InChI=1S/C26H19ClO3/c27-21-13-14-25(30-17-18-7-2-1-3-8-18)24(16-21)23-12-5-4-11-22(23)19-9-6-10-20(15-19)26(28)29/h1-16H,17H2,(H,28,29) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Displacement of [3H]PGE2 from EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50183182
(2''-benzyloxy-5''-chloro-[1,1';2',1'']terphenyl-3-...)Show SMILES OC(=O)c1cccc(c1)-c1ccccc1-c1cc(Cl)ccc1OCc1ccccc1 Show InChI InChI=1S/C26H19ClO3/c27-21-13-14-25(30-17-18-7-2-1-3-8-18)24(16-21)23-12-5-4-11-22(23)19-9-6-10-20(15-19)26(28)29/h1-16H,17H2,(H,28,29) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human)) | BDBM50413675
(CHEMBL514425)Show SMILES OC(=O)c1cc(F)cc(c1)-c1ccccc1-c1ccccc1OCc1ccccc1 Show InChI InChI=1S/C26H19FO3/c27-21-15-19(14-20(16-21)26(28)29)22-10-4-5-11-23(22)24-12-6-7-13-25(24)30-17-18-8-2-1-3-9-18/h1-16H,17H2,(H,28,29) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 63.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Binding affinity to EP1 receptor |
Bioorg Med Chem Lett 19: 497-501 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.032
BindingDB Entry DOI: 10.7270/Q2N879N5 |
More data for this
Ligand-Target Pair | |
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