Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50025356 (4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM235657 (4-Bromo-17α-hydroxypregn-4-ene-3,20-dione (7b...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM235655 (17α-Hydroxypregn-4-ene-3,20-dione (5)) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM233039 (Finasteride (3)) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Universidad Nacional Autónoma de México | Assay Description The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ... | J Enzyme Inhib Med Chem 25: 306-11 (2010) Article DOI: 10.3109/14756360903179401 BindingDB Entry DOI: 10.7270/Q2G15ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM233040 (17α-Acetoxyprogesterone (6)) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Universidad Nacional Autónoma de México | Assay Description The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ... | J Enzyme Inhib Med Chem 25: 306-11 (2010) Article DOI: 10.3109/14756360903179401 BindingDB Entry DOI: 10.7270/Q2G15ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM233043 (6-Chloro-3,20-dioxopregna-4,6-diene-17α-yl ac...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Universidad Nacional Autónoma de México | Assay Description The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ... | J Enzyme Inhib Med Chem 25: 306-11 (2010) Article DOI: 10.3109/14756360903179401 BindingDB Entry DOI: 10.7270/Q2G15ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM233042 (3,20-Dioxo-6,7-epoxypregn-4-ene-7α-yl acetate...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Universidad Nacional Autónoma de México | Assay Description The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ... | J Enzyme Inhib Med Chem 25: 306-11 (2010) Article DOI: 10.3109/14756360903179401 BindingDB Entry DOI: 10.7270/Q2G15ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM235659 (4-Bromo-3,20-dioxopregn-4-ene-17-yl-4-ethylbenzoat...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM235656 (4-Chloro-17α-hydroxypregn-4-ene-3,20-dione (7...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM233041 (3,20-Dioxopregna-4,6-dien-17α-yl acetate (7)) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Universidad Nacional Autónoma de México | Assay Description The reaction mixture contained a final volume of 1 mL: 1 mM dithiothreitol, sodium phosphate buffer 40 mM, at pH 6.5 for human prostate, 2 mM NADPH, ... | J Enzyme Inhib Med Chem 25: 306-11 (2010) Article DOI: 10.3109/14756360903179401 BindingDB Entry DOI: 10.7270/Q2G15ZQ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM235658 (4-Chloro-3,20-dioxopregn-4-ene-17-yl-4-ethylbenzoa...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cDNA, FLJ78895, highly similar to 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM235654 (3,20-Dioxopregn-4-ene-17-yl acetate (4)) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | 6.5 | 37 |
Metropolitan University-Xochimilco | Assay Description The reaction mixtures contained a final volume of 1 mL, 1 mM DTT, sodium phosphate buffer 40 mM, at pH 6.5, 2 mM, NADPH, 2 nM [1,2,6,7-3H]T or [1,2,3... | J Enzyme Inhib Med Chem 26: 712-9 (2011) Article DOI: 10.3109/14756366.2010.548330 BindingDB Entry DOI: 10.7270/Q25719XS | |||||||||||
More data for this Ligand-Target Pair |