Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E-selectin (Mus musculus) | BDBM50060511 ((R)-4-Methylcarbamoyl-4-[(S)-2-(2-tetradecyl-hexad...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kanebo Curated by ChEMBL | Assay Description In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) binding | J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50060514 ((S)-4-Methylcarbamoyl-4-[(R)-2-(2-tetradecyl-hexad...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kanebo Curated by ChEMBL | Assay Description In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) binding | J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50087285 (4-Methylcarbamoyl-4-[2-(2-tetradecyl-hexadecanoyla...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Organon K.K. Curated by ChEMBL | Assay Description Evaluated for the inhibitory activity against Selectin E | J Med Chem 43: 1476-83 (2000) BindingDB Entry DOI: 10.7270/Q2K64JRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50087287 (4-(3-Carboxy-phenoxy)-3-(4-octadecanoylamino-benzo...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Organon K.K. Curated by ChEMBL | Assay Description Evaluated for the inhibitory activity against Selectin E | J Med Chem 43: 1476-83 (2000) BindingDB Entry DOI: 10.7270/Q2K64JRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50408284 (CHEMBL2029056) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Organon K.K. Curated by ChEMBL | Assay Description Evaluated for the inhibitory activity against Selectin E | J Med Chem 43: 1476-83 (2000) BindingDB Entry DOI: 10.7270/Q2K64JRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50408284 (CHEMBL2029056) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kanebo Curated by ChEMBL | Assay Description In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) binding | J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50087288 (5-[4-Carboxy-2-(4-octadecanoylamino-benzoylamino)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Organon K.K. Curated by ChEMBL | Assay Description Evaluated for the inhibitory activity against Selectin E | J Med Chem 43: 1476-83 (2000) BindingDB Entry DOI: 10.7270/Q2K64JRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50288934 (2-[3,5-dihydroxy-2-(6-hydroxy-2-hydroxymethyl-4-ox...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Organon K.K. Curated by ChEMBL | Assay Description Evaluated for the inhibitory activity against Selectin E | J Med Chem 43: 1476-83 (2000) BindingDB Entry DOI: 10.7270/Q2K64JRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50450369 (SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kanebo Curated by ChEMBL | Assay Description In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) binding | J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50060512 ((R)-4-Methylcarbamoyl-4-[(R)-2-(2-tetradecyl-hexad...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kanebo Curated by ChEMBL | Assay Description In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) binding | J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50060515 ((S)-4-Methylcarbamoyl-4-[(S)-2-(2-tetradecyl-hexad...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kanebo Curated by ChEMBL | Assay Description In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) binding | J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50087284 (5-{4-Carboxy-2-[3-(4-octadecanoylamino-phenyl)-3-o...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 1.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Organon K.K. Curated by ChEMBL | Assay Description Evaluated for the inhibitory activity against Selectin E | J Med Chem 43: 1476-83 (2000) BindingDB Entry DOI: 10.7270/Q2K64JRZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E-selectin (Mus musculus) | BDBM50450369 (SIALYL LEWIS X | Sialyl LeX | Sialyl lewis-x | sLe...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 3.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for its ability to inhibit sialyl Lewis X dependent binding of HL-60 cells to Selectin E fusion protein | Bioorg Med Chem Lett 6: 569-572 (1996) Article DOI: 10.1016/0960-894X(96)00071-6 BindingDB Entry DOI: 10.7270/Q2Q81D24 | |||||||||||
More data for this Ligand-Target Pair |