Compile Data Set for Download or QSAR

Found 101 hits of ic50 for UniProtKB: Q61606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Mus musculus)	BDBM50566470 (CHEMBL4857523) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](O)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O)C(O)=O)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at mouse GCGR expressed in CHO-K1 cells assessed as inhibition of glucogon-induced cAMP production				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02069 BindingDB Entry DOI: 10.7270/Q23J3HQT
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50566469 (CHEMBL4876736) Show SMILES CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](O)Cc1ccccc1)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at mouse GCGR expressed in CHO-K1 cells assessed as inhibition of glucogon-induced cAMP production				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02069 BindingDB Entry DOI: 10.7270/Q23J3HQT
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075766 (4-[5-(4-Chloro-phenyl)-3-(2-propoxy-phenyl)-1H-pyr...) Show SMILES CCCOc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN2O/c1-2-15-28-23-6-4-3-5-20(23)21-16-22(17-7-9-19(25)10-8-17)27-24(21)18-11-13-26-14-12-18/h3-14,16,27H,2,15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075775 (4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...) Show SMILES CCCOc1ccc(Br)cc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H20BrClN2O/c1-2-13-29-23-8-5-18(25)14-20(23)21-15-22(16-3-6-19(26)7-4-16)28-24(21)17-9-11-27-12-10-17/h3-12,14-15,28H,2,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075787 (4-[3-(4-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...) Show SMILES CCCOc1cc(Br)ccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H20BrClN2O/c1-2-13-29-23-14-18(25)5-8-20(23)21-15-22(16-3-6-19(26)7-4-16)28-24(21)17-9-11-27-12-10-17/h3-12,14-15,28H,2,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075783 (4-[5-(4-Chloro-phenyl)-3-(5-chloro-2-propoxy-pheny...) Show SMILES CCCOc1ccc(Cl)cc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H20Cl2N2O/c1-2-13-29-23-8-7-19(26)14-20(23)21-15-22(16-3-5-18(25)6-4-16)28-24(21)17-9-11-27-12-10-17/h3-12,14-15,28H,2,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075780 (4-[5-(4-Chloro-phenyl)-3-isopropyl-1H-pyrrol-2-yl]...) Show SMILES CC(C)c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H17ClN2/c1-12(2)16-11-17(13-3-5-15(19)6-4-13)21-18(16)14-7-9-20-10-8-14/h3-12,21H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075748 (4-[5-(4-Chloro-phenyl)-3-cyclohexyl-1H-pyrrol-2-yl...) Show SMILES Clc1ccc(cc1)-c1cc(C2CCCCC2)c([nH]1)-c1ccncc1 Show InChI InChI=1S/C21H21ClN2/c22-18-8-6-16(7-9-18)20-14-19(15-4-2-1-3-5-15)21(24-20)17-10-12-23-13-11-17/h6-15,24H,1-5H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075772 (4-[3-(2-Butoxy-phenyl)-5-(4-chloro-phenyl)-1H-pyrr...) Show SMILES CCCCOc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H23ClN2O/c1-2-3-16-29-24-7-5-4-6-21(24)22-17-23(18-8-10-20(26)11-9-18)28-25(22)19-12-14-27-15-13-19/h4-15,17,28H,2-3,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007239 (CHEMBL3238226) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cncc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(30.07,-58.93,;30.05,-57.39,;28.71,-56.63,;28.71,-58.14,;31.38,-56.6,;31.36,-55.06,;32.68,-54.28,;32.63,-52.74,;33.84,-51.79,;35.32,-52.2,;33.31,-50.34,;31.76,-50.4,;31.35,-51.88,;30.16,-50.89,;28.71,-51.43,;28.45,-52.94,;29.64,-53.93,;31.09,-53.4,;27.01,-53.48,;25.83,-52.49,;25.56,-54.01,;26.75,-54.99,;34.08,-49.01,;35.62,-49.02,;36.4,-47.69,;35.64,-46.35,;34.1,-46.35,;33.33,-45.01,;33.32,-47.68,;34.01,-55.06,;33.98,-56.61,;35.31,-57.39,;36.66,-56.64,;36.68,-55.1,;35.35,-54.32,;37.98,-57.43,;37.96,-58.97,;39.32,-56.68,;40.64,-57.46,;41.99,-56.71,;43.38,-57.34,;44.42,-56.21,;43.67,-54.87,;42.16,-55.17,)| Show InChI InChI=1S/C33H43ClN8O2/c1-31(2,3)14-13-26(21-7-9-22(10-8-21)29(43)36-20-27-38-40-41-39-27)42-30(44)28(23-17-25(34)19-35-18-23)37-33(42)15-11-24(12-16-33)32(4,5)6/h7-10,17-19,24,26H,11-16,20H2,1-6H3,(H,36,43)(H,38,39,40,41)/t24-,26-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007231 (CHEMBL3238221) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1ccc(F)cc1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(52.44,-30.45,;52.42,-28.91,;51.08,-28.16,;51.08,-29.67,;53.74,-28.13,;53.72,-26.59,;55.05,-25.8,;54.99,-24.27,;56.21,-23.32,;57.68,-23.73,;55.67,-21.87,;54.13,-21.93,;53.71,-23.41,;52.53,-22.42,;51.08,-22.95,;50.82,-24.47,;52,-25.46,;53.45,-24.92,;49.38,-25,;48.19,-24.02,;47.93,-25.54,;49.12,-26.52,;56.45,-20.54,;57.99,-20.55,;58.77,-19.22,;58.01,-17.88,;58.78,-16.55,;56.46,-17.87,;55.69,-19.2,;56.37,-26.59,;56.35,-28.13,;57.68,-28.92,;59.02,-28.17,;59.04,-26.63,;57.72,-25.84,;60.35,-28.96,;60.33,-30.5,;61.69,-28.2,;63.01,-28.99,;64.35,-28.23,;65.75,-28.87,;66.79,-27.74,;66.04,-26.4,;64.53,-26.7,)| Show InChI InChI=1S/C34H44FN7O2/c1-32(2,3)18-17-27(22-7-9-24(10-8-22)30(43)36-21-28-38-40-41-39-28)42-31(44)29(23-11-13-26(35)14-12-23)37-34(42)19-15-25(16-20-34)33(4,5)6/h7-14,25,27H,15-21H2,1-6H3,(H,36,43)(H,38,39,40,41)/t25-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007240 (CHEMBL3238228) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cnccc1C(F)(F)F)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(5.79,-14.06,;5.77,-12.52,;4.43,-11.77,;4.43,-13.28,;7.1,-11.73,;7.08,-10.19,;8.4,-9.41,;8.35,-7.87,;9.56,-6.92,;11.04,-7.34,;9.03,-5.47,;7.48,-5.53,;7.07,-7.01,;5.88,-6.03,;4.43,-6.56,;4.17,-8.08,;5.36,-9.06,;6.8,-8.53,;2.73,-8.61,;1.55,-7.62,;1.28,-9.14,;2.47,-10.13,;9.8,-4.14,;11.34,-4.16,;12.12,-2.83,;11.36,-1.48,;9.82,-1.48,;9.04,-2.81,;7.5,-2.8,;6.74,-1.47,;6.72,-4.13,;5.96,-2.79,;9.73,-10.19,;9.7,-11.74,;11.03,-12.52,;12.38,-11.77,;12.4,-10.23,;11.07,-9.45,;13.7,-12.56,;13.68,-14.1,;15.04,-11.81,;16.36,-12.59,;17.71,-11.84,;19.1,-12.48,;20.15,-11.34,;19.39,-10,;17.88,-10.31,)| Show InChI InChI=1S/C34H43F3N8O2/c1-31(2,3)15-13-26(21-7-9-22(10-8-21)29(46)39-20-27-41-43-44-42-27)45-30(47)28(24-19-38-18-14-25(24)34(35,36)37)40-33(45)16-11-23(12-17-33)32(4,5)6/h7-10,14,18-19,23,26H,11-13,15-17,20H2,1-6H3,(H,39,46)(H,41,42,43,44)/t23-,26-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007228 (CHEMBL3238219) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cccc(F)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(7.91,-30.88,;7.89,-29.34,;6.55,-28.59,;6.56,-30.1,;9.22,-28.56,;9.2,-27.02,;10.52,-26.23,;10.47,-24.7,;11.68,-23.74,;13.16,-24.16,;11.15,-22.3,;9.6,-22.36,;9.19,-23.83,;8,-22.85,;6.56,-23.38,;6.29,-24.9,;7.48,-25.88,;8.93,-25.35,;4.85,-25.43,;3.67,-24.45,;3.41,-25.96,;4.59,-26.95,;11.92,-20.97,;13.47,-20.98,;14.24,-19.65,;13.48,-18.31,;11.94,-18.3,;11.17,-16.96,;11.16,-19.63,;11.85,-27.02,;11.83,-28.56,;13.15,-29.35,;14.5,-28.59,;14.52,-27.06,;13.19,-26.27,;15.82,-29.39,;15.8,-30.92,;17.16,-28.63,;18.49,-29.42,;19.83,-28.66,;21.22,-29.3,;22.27,-28.17,;21.51,-26.82,;20,-27.13,)| Show InChI InChI=1S/C34H44FN7O2/c1-32(2,3)17-16-27(22-10-12-23(13-11-22)30(43)36-21-28-38-40-41-39-28)42-31(44)29(24-8-7-9-26(35)20-24)37-34(42)18-14-25(15-19-34)33(4,5)6/h7-13,20,25,27H,14-19,21H2,1-6H3,(H,36,43)(H,38,39,40,41)/t25-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007223 (CHEMBL3238215) Show SMILES CC(C)(C)[C@H]1CC[C@]2(CC1)N=C(C(=O)N2[C@H](CCC1(C)CC1)c1ccc(cc1)C(=O)NCc1nn[nH]n1)c1cc(Cl)cc(Cl)c1 |r,wU:4.3,15.17,wD:7.6,c:11,(1.56,-50.44,;2.75,-51.42,;1.3,-51.96,;2.49,-52.94,;4.19,-50.89,;4.45,-49.37,;5.9,-48.84,;7.08,-49.83,;6.82,-51.35,;5.37,-51.88,;7.5,-48.35,;9.04,-48.29,;9.57,-49.74,;11.05,-50.15,;8.36,-50.69,;8.42,-52.22,;7.09,-53.01,;7.11,-54.55,;5.79,-55.33,;4.44,-54.58,;6.55,-56.66,;5.02,-56.65,;9.74,-53.01,;9.72,-54.55,;11.04,-55.34,;12.39,-54.59,;12.41,-53.05,;11.09,-52.26,;13.72,-55.38,;13.69,-56.92,;15.05,-54.62,;16.38,-55.41,;17.72,-54.65,;19.12,-55.29,;20.16,-54.16,;19.41,-52.82,;17.9,-53.12,;9.82,-46.96,;9.06,-45.62,;9.83,-44.29,;9.07,-42.96,;11.37,-44.3,;12.14,-45.64,;13.68,-45.65,;11.36,-46.97,)| Show InChI InChI=1S/C34H41Cl2N7O2/c1-32(2,3)24-9-13-34(14-10-24)38-29(23-17-25(35)19-26(36)18-23)31(45)43(34)27(11-12-33(4)15-16-33)21-5-7-22(8-6-21)30(44)37-20-28-39-41-42-40-28/h5-8,17-19,24,27H,9-16,20H2,1-4H3,(H,37,44)(H,39,40,41,42)/t24-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007219 (CHEMBL3238214) Show SMILES CC(C)(C)[C@H]1CC[C@]2(CC1)N=C(C(=O)N2[C@H](CCC(F)(F)F)c1ccc(cc1)C(=O)NCc1nn[nH]n1)c1cc(Cl)cc(Cl)c1 |r,wU:4.3,15.17,wD:7.6,c:11,(50.24,-37.05,;51.42,-38.04,;49.98,-38.57,;51.16,-39.56,;52.86,-37.5,;53.12,-35.99,;54.57,-35.46,;55.76,-36.44,;55.5,-37.96,;54.05,-38.49,;56.17,-34.96,;57.72,-34.9,;58.25,-36.35,;59.73,-36.77,;57.04,-37.3,;57.09,-38.84,;55.77,-39.62,;55.79,-41.16,;54.46,-41.95,;54.48,-43.49,;53.12,-41.19,;53.12,-42.7,;58.42,-39.62,;58.4,-41.17,;59.72,-41.95,;61.07,-41.2,;61.09,-39.66,;59.76,-38.88,;62.39,-41.99,;62.37,-43.53,;63.73,-41.24,;65.05,-42.02,;66.4,-41.27,;67.79,-41.9,;68.84,-40.77,;68.08,-39.43,;66.57,-39.73,;58.49,-33.57,;57.73,-32.24,;58.51,-30.91,;57.74,-29.57,;60.05,-30.91,;60.81,-32.25,;62.35,-32.26,;60.04,-33.59,)| Show InChI InChI=1S/C31H34Cl2F3N7O2/c1-29(2,3)21-8-11-30(12-9-21)38-26(20-14-22(32)16-23(33)15-20)28(45)43(30)24(10-13-31(34,35)36)18-4-6-19(7-5-18)27(44)37-17-25-39-41-42-40-25/h4-7,14-16,21,24H,8-13,17H2,1-3H3,(H,37,44)(H,39,40,41,42)/t21-,24-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50360601 (CHEMBL1933349 | MK-0893) Show SMILES COc1ccc2cc(ccc2c1)-c1cc(nn1[C@@H](C)c1ccc(cc1)C(=O)NCCC(O)=O)-c1cc(Cl)cc(Cl)c1 |r| Show InChI InChI=1S/C32H27Cl2N3O4/c1-19(20-3-5-21(6-4-20)32(40)35-12-11-31(38)39)37-30(18-29(36-37)25-14-26(33)17-27(34)15-25)24-8-7-23-16-28(41-2)10-9-22(23)13-24/h3-10,13-19H,11-12H2,1-2H3,(H,35,40)(H,38,39)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at mouse GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...				J Med Chem 55: 6137-48 (2012) Article DOI: 10.1021/jm300579z BindingDB Entry DOI: 10.7270/Q2X63P2C
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007226 (CHEMBL3238218) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cccc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(54.79,-14.62,;54.77,-13.08,;53.43,-12.33,;53.44,-13.84,;56.1,-12.29,;56.08,-10.75,;57.4,-9.97,;57.35,-8.43,;58.56,-7.48,;60.04,-7.9,;58.03,-6.03,;56.49,-6.09,;56.07,-7.57,;54.88,-6.59,;53.44,-7.12,;53.17,-8.64,;54.36,-9.62,;55.81,-9.09,;51.74,-9.17,;50.55,-8.18,;50.29,-9.7,;51.47,-10.69,;58.81,-4.7,;60.35,-4.72,;61.12,-3.39,;60.36,-2.04,;58.82,-2.04,;58.05,-.7,;58.04,-3.37,;58.73,-10.75,;58.71,-12.3,;60.03,-13.08,;61.38,-12.33,;61.4,-10.79,;60.07,-10.01,;62.7,-13.12,;62.68,-14.66,;64.04,-12.37,;65.37,-13.15,;66.71,-12.4,;68.11,-13.04,;69.15,-11.9,;68.39,-10.56,;66.88,-10.87,)| Show InChI InChI=1S/C34H44ClN7O2/c1-32(2,3)17-16-27(22-10-12-23(13-11-22)30(43)36-21-28-38-40-41-39-28)42-31(44)29(24-8-7-9-26(35)20-24)37-34(42)18-14-25(15-19-34)33(4,5)6/h7-13,20,25,27H,14-19,21H2,1-6H3,(H,36,43)(H,38,39,40,41)/t25-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007296 (CHEMBL3238246) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:6.5,15.19,wD:12.13,c:10,(14.39,-29.64,;15.92,-29.51,;16.8,-30.77,;15.33,-30.92,;16.51,-28.08,;15.58,-26.85,;16.18,-25.43,;15.24,-24.21,;15.69,-22.73,;17.14,-22.22,;14.42,-21.86,;13.2,-22.79,;13.71,-24.25,;12.17,-24.12,;11.29,-25.39,;11.95,-26.78,;13.48,-26.9,;14.36,-25.64,;11.08,-28.04,;9.54,-28.18,;11.96,-29.31,;10.19,-29.31,;14.39,-20.32,;15.7,-19.52,;15.67,-17.98,;16.98,-17.18,;14.32,-17.24,;13,-18.03,;11.65,-17.3,;13.04,-19.57,;17.71,-25.32,;18.39,-23.94,;19.92,-23.82,;20.79,-25.1,;20.12,-26.48,;18.58,-26.59,;22.32,-24.98,;23.19,-26.25,;22.99,-23.59,;24.53,-23.47,;25.2,-22.08,;26.72,-21.81,;26.92,-20.29,;25.53,-19.61,;24.47,-20.73,)| Show InChI InChI=1S/C34H43Cl2N7O2/c1-32(2,3)14-13-27(21-7-9-22(10-8-21)30(44)37-20-28-39-41-42-40-28)43-31(45)29(23-17-25(35)19-26(36)18-23)38-34(43)15-11-24(12-16-34)33(4,5)6/h7-10,17-19,24,27H,11-16,20H2,1-6H3,(H,37,44)(H,39,40,41,42)/t24-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007225 (CHEMBL3238217) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(F)cc(F)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(30.08,-13.9,;30.07,-12.36,;28.72,-11.6,;28.73,-13.11,;31.39,-11.57,;31.37,-10.03,;32.7,-9.25,;32.64,-7.71,;33.85,-6.76,;35.33,-7.17,;33.32,-5.31,;31.78,-5.37,;31.36,-6.85,;30.18,-5.86,;28.73,-6.4,;28.47,-7.91,;29.65,-8.9,;31.1,-8.37,;27.03,-8.45,;25.84,-7.46,;25.58,-8.98,;26.77,-9.96,;34.1,-3.98,;33.34,-2.65,;34.11,-1.32,;33.35,.03,;35.65,-1.32,;36.41,-2.66,;37.95,-2.67,;35.64,-3.99,;34.02,-10.03,;34,-11.58,;35.32,-12.36,;36.67,-11.61,;36.69,-10.07,;35.37,-9.29,;37.99,-12.4,;37.97,-13.94,;39.33,-11.65,;40.66,-12.43,;42,-11.68,;43.4,-12.31,;44.44,-11.18,;43.68,-9.84,;42.18,-10.14,)| Show InChI InChI=1S/C34H43F2N7O2/c1-32(2,3)14-13-27(21-7-9-22(10-8-21)30(44)37-20-28-39-41-42-40-28)43-31(45)29(23-17-25(35)19-26(36)18-23)38-34(43)15-11-24(12-16-34)33(4,5)6/h7-10,17-19,24,27H,11-16,20H2,1-6H3,(H,37,44)(H,39,40,41,42)/t24-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007233 (CHEMBL3238223) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cccc(c1)C(F)(F)F)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(29.88,-44.48,;29.86,-42.94,;28.52,-42.19,;28.53,-43.7,;31.19,-42.16,;31.17,-40.62,;32.49,-39.83,;32.44,-38.3,;33.65,-37.35,;35.13,-37.76,;33.12,-35.9,;31.58,-35.96,;31.16,-37.44,;29.97,-36.45,;28.53,-36.98,;28.26,-38.5,;29.45,-39.49,;30.9,-38.95,;26.83,-39.03,;25.64,-38.05,;25.38,-39.57,;26.56,-40.55,;33.9,-34.57,;33.13,-33.23,;33.91,-31.9,;35.45,-31.91,;36.21,-33.25,;35.44,-34.58,;37.75,-33.26,;38.51,-34.6,;38.53,-31.93,;39.29,-33.26,;33.82,-40.62,;33.8,-42.16,;35.12,-42.95,;36.47,-42.2,;36.49,-40.66,;35.16,-39.87,;37.79,-42.99,;37.77,-44.53,;39.13,-42.23,;40.46,-43.02,;41.8,-42.26,;43.2,-42.9,;44.24,-41.77,;43.48,-40.43,;41.97,-40.73,)| Show InChI InChI=1S/C35H44F3N7O2/c1-32(2,3)17-16-27(22-10-12-23(13-11-22)30(46)39-21-28-41-43-44-42-28)45-31(47)29(24-8-7-9-26(20-24)35(36,37)38)40-34(45)18-14-25(15-19-34)33(4,5)6/h7-13,20,25,27H,14-19,21H2,1-6H3,(H,39,46)(H,41,42,43,44)/t25-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075752 (4-[5-(4-Chloro-phenyl)-3-(2-isobutoxy-phenyl)-1H-p...) Show SMILES CC(C)COc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C25H23ClN2O/c1-17(2)16-29-24-6-4-3-5-21(24)22-15-23(18-7-9-20(26)10-8-18)28-25(22)19-11-13-27-14-12-19/h3-15,17,28H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007224 (CHEMBL3238216) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(F)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(7.31,-14.38,;7.3,-12.84,;5.95,-12.09,;5.96,-13.59,;8.62,-12.05,;8.6,-10.51,;9.93,-9.73,;9.87,-8.19,;11.08,-7.24,;12.56,-7.66,;10.55,-5.79,;9.01,-5.85,;8.59,-7.33,;7.4,-6.35,;5.96,-6.88,;5.7,-8.4,;6.88,-9.38,;8.33,-8.85,;4.26,-8.93,;3.07,-7.94,;2.81,-9.46,;3.99,-10.45,;11.33,-4.46,;12.87,-4.48,;13.64,-3.15,;15.18,-3.15,;12.88,-1.8,;11.34,-1.8,;10.57,-.46,;10.56,-3.13,;11.25,-10.51,;11.23,-12.06,;12.55,-12.84,;13.9,-12.09,;13.92,-10.55,;12.6,-9.77,;15.22,-12.88,;15.2,-14.42,;16.56,-12.13,;17.89,-12.91,;19.23,-12.16,;20.63,-12.8,;21.67,-11.66,;20.91,-10.32,;19.4,-10.62,)| Show InChI InChI=1S/C34H43ClFN7O2/c1-32(2,3)14-13-27(21-7-9-22(10-8-21)30(44)37-20-28-39-41-42-40-28)43-31(45)29(23-17-25(35)19-26(36)18-23)38-34(43)15-11-24(12-16-34)33(4,5)6/h7-10,17-19,24,27H,11-16,20H2,1-6H3,(H,37,44)(H,39,40,41,42)/t24-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007232 (CHEMBL3238222) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1ccc(F)c(F)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(5.5,-43.18,;5.48,-41.64,;4.14,-40.89,;4.15,-42.4,;6.81,-40.86,;6.79,-39.32,;8.11,-38.53,;8.06,-37,;9.27,-36.05,;10.75,-36.46,;8.74,-34.6,;7.19,-34.66,;6.78,-36.14,;5.59,-35.15,;4.14,-35.68,;3.88,-37.2,;5.07,-38.19,;6.52,-37.65,;2.44,-37.73,;1.26,-36.75,;1,-38.27,;2.18,-39.25,;9.51,-33.27,;8.75,-31.93,;9.53,-30.6,;11.07,-30.61,;11.85,-29.28,;11.83,-31.95,;13.37,-31.96,;11.06,-33.28,;9.44,-39.32,;9.42,-40.86,;10.74,-41.65,;12.09,-40.9,;12.11,-39.36,;10.78,-38.57,;13.41,-41.69,;13.39,-43.23,;14.75,-40.93,;16.08,-41.72,;17.42,-40.96,;18.81,-41.6,;19.86,-40.47,;19.1,-39.13,;17.59,-39.43,)| Show InChI InChI=1S/C34H43F2N7O2/c1-32(2,3)16-15-27(21-7-9-22(10-8-21)30(44)37-20-28-39-41-42-40-28)43-31(45)29(23-11-12-25(35)26(36)19-23)38-34(43)17-13-24(14-18-34)33(4,5)6/h7-12,19,24,27H,13-18,20H2,1-6H3,(H,37,44)(H,39,40,41,42)/t24-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007230 (CHEMBL3238220) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:15.19,6.5,wD:12.13,c:10,(32.97,-30.73,;32.95,-29.19,;31.61,-28.44,;31.61,-29.95,;34.28,-28.41,;34.26,-26.87,;35.58,-26.08,;35.53,-24.55,;36.74,-23.6,;38.22,-24.01,;36.21,-22.15,;34.66,-22.21,;34.25,-23.69,;33.06,-22.7,;31.61,-23.23,;31.35,-24.75,;32.54,-25.74,;33.99,-25.2,;29.91,-25.28,;28.73,-24.3,;28.46,-25.82,;29.65,-26.8,;36.98,-20.82,;38.53,-20.83,;39.3,-19.5,;38.54,-18.16,;37,-18.15,;36.22,-19.48,;39.32,-16.83,;40.86,-16.84,;38.56,-15.49,;40.08,-15.48,;36.91,-26.87,;36.88,-28.41,;38.21,-29.2,;39.56,-28.45,;39.58,-26.91,;38.25,-26.12,;40.88,-29.24,;40.86,-30.78,;42.22,-28.48,;43.54,-29.27,;44.89,-28.51,;46.28,-29.15,;47.33,-28.02,;46.57,-26.68,;45.06,-26.98,)| Show InChI InChI=1S/C35H44F3N7O2/c1-32(2,3)18-17-27(22-7-9-24(10-8-22)30(46)39-21-28-41-43-44-42-28)45-31(47)29(23-11-13-26(14-12-23)35(36,37)38)40-34(45)19-15-25(16-20-34)33(4,5)6/h7-14,25,27H,15-21H2,1-6H3,(H,39,46)(H,41,42,43,44)/t25-,27-,34-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007241 (CHEMBL3238229) Show SMILES CC(C)[C@H]1CC[C@]2(CC1)N=C(C(=O)N2[C@H](CCC(C)(C)C)c1ccc(cc1)C(=O)NCc1nn[nH]n1)c1cc(Cl)cc(Cl)c1 |r,wU:14.16,3.2,wD:6.5,c:10,(22.68,-7.09,;24,-7.87,;23.99,-9.41,;25.34,-7.11,;25.6,-5.59,;27.05,-5.06,;28.24,-6.05,;27.98,-7.57,;26.53,-8.1,;28.65,-4.57,;30.2,-4.51,;30.73,-5.96,;32.21,-6.37,;29.52,-6.91,;29.57,-8.44,;28.25,-9.23,;28.27,-10.77,;26.94,-11.56,;26.96,-13.1,;25.6,-10.8,;25.6,-12.31,;30.9,-9.23,;30.87,-10.78,;32.2,-11.56,;33.55,-10.81,;33.57,-9.27,;32.24,-8.48,;34.87,-11.6,;34.85,-13.14,;36.21,-10.85,;37.53,-11.63,;38.88,-10.88,;40.27,-11.51,;41.32,-10.38,;40.56,-9.04,;39.05,-9.34,;30.97,-3.18,;30.21,-1.85,;30.99,-.51,;30.22,.83,;32.53,-.52,;33.29,-1.86,;34.83,-1.87,;32.52,-3.19,)| Show InChI InChI=1S/C33H41Cl2N7O2/c1-20(2)21-10-14-33(15-11-21)37-29(24-16-25(34)18-26(35)17-24)31(44)42(33)27(12-13-32(3,4)5)22-6-8-23(9-7-22)30(43)36-19-28-38-40-41-39-28/h6-9,16-18,20-21,27H,10-15,19H2,1-5H3,(H,36,43)(H,38,39,40,41)/t21-,27-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50071899 (4-[5-(4-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H14ClFN2/c22-17-5-1-15(2-6-17)20-13-19(14-3-7-18(23)8-4-14)21(25-20)16-9-11-24-12-10-16/h1-13,25H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075764 (4-[3,5-Bis-(4-chloro-phenyl)-1H-pyrrol-2-yl]-pyrid...) Show SMILES Clc1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H14Cl2N2/c22-17-5-1-14(2-6-17)19-13-20(15-3-7-18(23)8-4-15)25-21(19)16-9-11-24-12-10-16/h1-13,25H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075751 (4-[4-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrol-2-...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H14FN3/c23-19-7-5-16(6-8-19)20-13-21(17-3-1-15(14-24)2-4-17)26-22(20)18-9-11-25-12-10-18/h1-13,26H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075767 (4-[3-(3-Bromo-phenyl)-5-(4-chloro-phenyl)-1H-pyrro...) Show SMILES Clc1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1cccc(Br)c1 Show InChI InChI=1S/C21H14BrClN2/c22-17-3-1-2-16(12-17)19-13-20(14-4-6-18(23)7-5-14)25-21(19)15-8-10-24-11-9-15/h1-13,25H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of 125 I-glucagon to the murine glucagon receptor (mGLUR) expressed on ...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075758 (4-[5-(4-Chloro-phenyl)-3-(4-methoxy-phenyl)-1H-pyr...) Show SMILES COc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O/c1-26-19-8-4-15(5-9-19)20-14-21(16-2-6-18(23)7-3-16)25-22(20)17-10-12-24-13-11-17/h2-14,25H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075775 (4-[3-(5-Bromo-2-propoxy-phenyl)-5-(4-chloro-phenyl...) Show SMILES CCCOc1ccc(Br)cc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H20BrClN2O/c1-2-13-29-23-8-5-18(25)14-20(23)21-15-22(16-3-6-19(26)7-4-16)28-24(21)17-9-11-27-12-10-17/h3-12,14-15,28H,2,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of 125 I-glucagon to the murine glucagon receptor (mGLUR) expressed on ...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075749 (4-[3-(2-Allyloxy-phenyl)-5-(4-chloro-phenyl)-1H-py...) Show SMILES Clc1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccccc1OCC=C Show InChI InChI=1S/C24H19ClN2O/c1-2-15-28-23-6-4-3-5-20(23)21-16-22(17-7-9-19(25)10-8-17)27-24(21)18-11-13-26-14-12-18/h2-14,16,27H,1,15H2	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007218 (CHEMBL3237928) Show SMILES CC(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:14.18,5.4,wD:11.12,c:9,(30.64,-43.26,;30.62,-41.72,;29.28,-40.97,;31.95,-40.94,;31.93,-39.4,;33.25,-38.61,;33.2,-37.07,;34.41,-36.12,;35.89,-36.54,;33.88,-34.68,;32.34,-34.74,;31.92,-36.21,;30.73,-35.23,;29.29,-35.76,;29.02,-37.28,;30.21,-38.26,;31.66,-37.73,;27.59,-37.81,;26.4,-36.82,;26.14,-38.34,;27.32,-39.33,;34.66,-33.35,;33.89,-32.01,;34.67,-30.68,;33.9,-29.34,;36.21,-30.69,;36.97,-32.03,;38.51,-32.04,;36.2,-33.36,;34.58,-39.39,;34.56,-40.94,;35.88,-41.72,;37.23,-40.97,;37.25,-39.43,;35.92,-38.65,;38.55,-41.76,;38.53,-43.3,;39.89,-41.01,;41.22,-41.79,;42.56,-41.04,;43.95,-41.68,;45,-40.54,;44.24,-39.2,;42.73,-39.51,)| Show InChI InChI=1S/C33H41Cl2N7O2/c1-20(2)6-11-27(21-7-9-22(10-8-21)30(43)36-19-28-38-40-41-39-28)42-31(44)29(23-16-25(34)18-26(35)17-23)37-33(42)14-12-24(13-15-33)32(3,4)5/h7-10,16-18,20,24,27H,6,11-15,19H2,1-5H3,(H,36,43)(H,38,39,40,41)/t24-,27-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007214 (CHEMBL3237925) Show SMILES CCCCC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:14.18,5.4,wD:11.12,c:9,(26.77,-29.67,;28.09,-28.88,;28.07,-27.34,;29.4,-26.56,;29.38,-25.02,;30.7,-24.23,;30.65,-22.69,;31.86,-21.74,;33.34,-22.16,;31.33,-20.3,;29.78,-20.36,;29.37,-21.83,;28.18,-20.85,;26.74,-21.38,;26.47,-22.9,;27.66,-23.88,;29.11,-23.35,;25.03,-23.43,;23.85,-22.45,;23.59,-23.96,;24.77,-24.95,;32.1,-18.97,;31.34,-17.63,;32.12,-16.3,;31.35,-14.97,;33.66,-16.31,;34.42,-17.65,;35.96,-17.66,;33.65,-18.98,;32.03,-25.02,;32.01,-26.56,;33.33,-27.35,;34.68,-26.59,;34.7,-25.06,;33.37,-24.27,;36,-27.39,;35.98,-28.92,;37.34,-26.63,;38.67,-27.42,;40.01,-26.66,;41.4,-27.3,;42.45,-26.17,;41.69,-24.82,;40.18,-25.13,)| Show InChI InChI=1S/C33H41Cl2N7O2/c1-5-6-7-8-27(21-9-11-22(12-10-21)30(43)36-20-28-38-40-41-39-28)42-31(44)29(23-17-25(34)19-26(35)18-23)37-33(42)15-13-24(14-16-33)32(2,3)4/h9-12,17-19,24,27H,5-8,13-16,20H2,1-4H3,(H,36,43)(H,38,39,40,41)/t24-,27-,33-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075754 (4-[5-(4-Chloro-phenyl)-3-(2-ethoxy-phenyl)-1H-pyrr...) Show SMILES CCOc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H19ClN2O/c1-2-27-22-6-4-3-5-19(22)20-15-21(16-7-9-18(24)10-8-16)26-23(20)17-11-13-25-14-12-17/h3-15,26H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075757 (4-[5-(2,4-Dichloro-phenyl)-3-(4-fluoro-phenyl)-1H-...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C21H13Cl2FN2/c22-15-3-6-17(19(23)11-15)20-12-18(13-1-4-16(24)5-2-13)21(26-20)14-7-9-25-10-8-14/h1-12,26H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075784 (4-[5-(4-Chloro-phenyl)-3-(2-hexyloxy-phenyl)-1H-py...) Show SMILES CCCCCCOc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H27ClN2O/c1-2-3-4-7-18-31-26-9-6-5-8-23(26)24-19-25(20-10-12-22(28)13-11-20)30-27(24)21-14-16-29-17-15-21/h5-6,8-17,19,30H,2-4,7,18H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007210 (CHEMBL3237922) Show SMILES CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:11.15,2.1,wD:8.9,c:6,(32.2,-13.03,;32.18,-11.49,;33.51,-10.71,;33.45,-9.17,;34.67,-8.22,;36.14,-8.63,;34.13,-6.77,;32.59,-6.83,;32.17,-8.31,;30.99,-7.32,;29.54,-7.86,;29.28,-9.37,;30.46,-10.36,;31.91,-9.83,;27.84,-9.91,;26.65,-8.92,;26.39,-10.44,;27.58,-11.42,;34.91,-5.44,;34.15,-4.11,;34.92,-2.78,;34.16,-1.44,;36.47,-2.78,;37.23,-4.12,;38.77,-4.13,;36.45,-5.46,;34.83,-11.49,;34.81,-13.04,;36.14,-13.82,;37.48,-13.07,;37.5,-11.53,;36.18,-10.75,;38.81,-13.86,;38.79,-15.4,;40.14,-13.11,;41.47,-13.89,;42.81,-13.14,;44.21,-13.77,;45.25,-12.64,;44.5,-11.3,;42.99,-11.6,)| Show InChI InChI=1S/C30H35Cl2N7O2/c1-5-24(18-6-8-19(9-7-18)27(40)33-17-25-35-37-38-36-25)39-28(41)26(20-14-22(31)16-23(32)15-20)34-30(39)12-10-21(11-13-30)29(2,3)4/h6-9,14-16,21,24H,5,10-13,17H2,1-4H3,(H,33,40)(H,35,36,37,38)/t21-,24-,30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075786 (4-[5-(4-Chloro-phenyl)-3-(2-methoxy-phenyl)-1H-pyr...) Show SMILES COc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H17ClN2O/c1-26-21-5-3-2-4-18(21)19-14-20(15-6-8-17(23)9-7-15)25-22(19)16-10-12-24-13-11-16/h2-14,25H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007440 (CHEMBL3237917) Show SMILES C[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nnn[nH]1 |r,wU:10.14,1.0,wD:7.8,c:5,(28.51,-39.62,;29.84,-38.83,;29.78,-37.3,;31,-36.35,;32.47,-36.76,;30.46,-34.9,;28.92,-34.96,;28.5,-36.44,;27.32,-35.45,;25.87,-35.98,;25.61,-37.5,;26.79,-38.49,;28.24,-37.95,;24.17,-38.03,;22.98,-37.05,;22.72,-38.56,;23.91,-39.55,;31.24,-33.57,;30.48,-32.23,;31.25,-30.9,;30.49,-29.57,;32.8,-30.91,;33.56,-32.25,;35.1,-32.26,;32.78,-33.58,;31.16,-39.62,;31.14,-41.16,;32.47,-41.95,;33.81,-41.19,;33.83,-39.66,;32.51,-38.87,;35.14,-41.99,;35.11,-43.52,;36.47,-41.23,;37.8,-42.02,;39.14,-41.26,;40.54,-41.9,;41.58,-40.77,;40.82,-39.42,;39.32,-39.73,)| Show InChI InChI=1S/C29H33Cl2N7O2/c1-17(18-5-7-19(8-6-18)26(39)32-16-24-34-36-37-35-24)38-27(40)25(20-13-22(30)15-23(31)14-20)33-29(38)11-9-21(10-12-29)28(2,3)4/h5-8,13-15,17,21H,9-12,16H2,1-4H3,(H,32,39)(H,34,35,36,37)/t17-,21-,29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007212 (CHEMBL3237924) Show SMILES CCCC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:13.17,4.3,wD:10.11,c:8,(5.36,-28.28,;5.34,-26.74,;6.67,-25.96,;6.65,-24.42,;7.97,-23.63,;7.92,-22.1,;9.13,-21.15,;10.61,-21.56,;8.6,-19.7,;7.05,-19.76,;6.64,-21.24,;5.45,-20.25,;4,-20.78,;3.74,-22.3,;4.93,-23.29,;6.38,-22.75,;2.3,-22.83,;1.12,-21.85,;.86,-23.37,;2.04,-24.35,;9.37,-18.37,;8.61,-17.03,;9.39,-15.7,;8.62,-14.37,;10.93,-15.71,;11.69,-17.05,;13.23,-17.06,;10.92,-18.38,;9.3,-24.42,;9.28,-25.96,;10.6,-26.75,;11.95,-26,;11.97,-24.46,;10.64,-23.67,;13.27,-26.79,;13.25,-28.33,;14.61,-26.03,;15.94,-26.82,;17.28,-26.06,;18.67,-26.7,;19.72,-25.57,;18.96,-24.23,;17.45,-24.53,)| Show InChI InChI=1S/C32H39Cl2N7O2/c1-5-6-7-26(20-8-10-21(11-9-20)29(42)35-19-27-37-39-40-38-27)41-30(43)28(22-16-24(33)18-25(34)17-22)36-32(41)14-12-23(13-15-32)31(2,3)4/h8-11,16-18,23,26H,5-7,12-15,19H2,1-4H3,(H,35,42)(H,37,38,39,40)/t23-,26-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007215 (CHEMBL3237927) Show SMILES CC(C)C[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:13.17,4.3,wD:10.11,c:8,(6.83,-40.7,;8.15,-39.91,;9.5,-40.66,;8.13,-38.37,;9.46,-37.59,;9.4,-36.05,;10.62,-35.1,;12.09,-35.51,;10.08,-33.65,;8.54,-33.71,;8.12,-35.19,;6.94,-34.2,;5.49,-34.74,;5.23,-36.25,;6.41,-37.24,;7.86,-36.71,;3.79,-36.79,;2.6,-35.8,;2.34,-37.32,;3.53,-38.3,;10.86,-32.32,;10.1,-30.99,;10.87,-29.66,;10.11,-28.32,;12.42,-29.66,;13.18,-31,;14.72,-31.01,;12.4,-32.33,;10.78,-38.37,;10.76,-39.92,;12.09,-40.7,;13.43,-39.95,;13.45,-38.41,;12.13,-37.62,;14.76,-40.74,;14.74,-42.28,;16.1,-39.99,;17.42,-40.77,;18.76,-40.02,;20.16,-40.65,;21.2,-39.52,;20.45,-38.18,;18.94,-38.48,)| Show InChI InChI=1S/C32H39Cl2N7O2/c1-19(2)14-26(20-6-8-21(9-7-20)29(42)35-18-27-37-39-40-38-27)41-30(43)28(22-15-24(33)17-25(34)16-22)36-32(41)12-10-23(11-13-32)31(3,4)5/h6-9,15-17,19,23,26H,10-14,18H2,1-5H3,(H,35,42)(H,37,38,39,40)/t23-,26-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075753 (4-[3,5-Bis-(4-fluoro-phenyl)-1H-pyrrol-2-yl]-pyrid...) Show SMILES Fc1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H14F2N2/c22-17-5-1-14(2-6-17)19-13-20(15-3-7-18(23)8-4-15)25-21(19)16-9-11-24-12-10-16/h1-13,25H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075781 (CHEMBL348555 | {2-[5-(4-Chloro-phenyl)-2-pyridin-4...) Show SMILES CCCNc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H22ClN3/c1-2-13-27-22-6-4-3-5-20(22)21-16-23(17-7-9-19(25)10-8-17)28-24(21)18-11-14-26-15-12-18/h3-12,14-16,27-28H,2,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the human glucagon receptor (GGR) expressed on CH...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075788 (4-[5-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-1H-pyrr...) Show SMILES Fc1ccc(cc1)-c1cc([nH]c1-c1ccncc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C21H14ClFN2/c22-17-3-1-2-16(12-17)20-13-19(14-4-6-18(23)7-5-14)21(25-20)15-8-10-24-11-9-15/h1-13,25H	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007211 (CHEMBL3237923) Show SMILES CCC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCc1nn[nH]n1 |r,wU:12.16,3.2,wD:9.10,c:7,(54.02,-13.47,;55.35,-12.68,;55.33,-11.14,;56.65,-10.36,;56.6,-8.82,;57.81,-7.87,;59.29,-8.29,;57.28,-6.42,;55.73,-6.48,;55.32,-7.96,;54.13,-6.98,;52.69,-7.51,;52.42,-9.02,;53.61,-10.01,;55.06,-9.48,;50.98,-9.56,;49.8,-8.57,;49.54,-10.09,;50.72,-11.07,;58.05,-5.09,;57.29,-3.76,;58.07,-2.43,;57.3,-1.09,;59.61,-2.43,;60.37,-3.78,;61.91,-3.78,;59.6,-5.11,;57.98,-11.14,;57.96,-12.69,;59.28,-13.47,;60.63,-12.72,;60.65,-11.18,;59.32,-10.4,;61.95,-13.51,;61.93,-15.05,;63.29,-12.76,;64.62,-13.54,;65.96,-12.79,;67.35,-13.42,;68.4,-12.29,;67.64,-10.95,;66.13,-11.25,)| Show InChI InChI=1S/C31H37Cl2N7O2/c1-5-6-25(19-7-9-20(10-8-19)28(41)34-18-26-36-38-39-37-26)40-29(42)27(21-15-23(32)17-24(33)16-21)35-31(40)13-11-22(12-14-31)30(2,3)4/h7-10,15-17,22,25H,5-6,11-14,18H2,1-4H3,(H,34,41)(H,36,37,38,39)/t22-,25-,31-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075750 (5-(4-Chloro-phenyl)-2-pyridin-4-yl-1H-pyrrole-3-ca...) Show SMILES CCOC(=O)c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C18H15ClN2O2/c1-2-23-18(22)15-11-16(12-3-5-14(19)6-4-12)21-17(15)13-7-9-20-10-8-13/h3-11,21H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards glucagon receptor determined by reduction in binding of [125I]-glucagon to the murine glucagon receptor (GGR) expressed on C...				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50007245 (CHEMBL3238234) Show SMILES CC(C)(C)CC[C@@H](N1C(=O)C(=N[C@@]11CC[C@@H](CC1)C(C)(C)C)c1cc(Cl)cc(Cl)c1)c1ccc(cc1)C(=O)NCCC(O)=O |r,wU:6.5,15.19,wD:12.13,c:10,(3.27,-43.71,;3.25,-42.17,;1.91,-41.41,;1.91,-42.92,;4.58,-41.38,;4.56,-39.84,;5.88,-39.06,;5.83,-37.52,;7.04,-36.57,;8.52,-36.98,;6.51,-35.12,;4.96,-35.18,;4.55,-36.66,;3.36,-35.67,;1.91,-36.21,;1.65,-37.72,;2.84,-38.71,;4.28,-38.18,;.31,-38.48,;-1.02,-37.71,;.3,-40.02,;-1.03,-39.24,;7.28,-33.79,;6.52,-32.46,;7.3,-31.13,;6.53,-29.79,;8.84,-31.13,;9.6,-32.47,;11.14,-32.48,;8.83,-33.8,;7.21,-39.84,;7.18,-41.39,;8.51,-42.17,;9.86,-41.42,;9.88,-39.88,;8.55,-39.1,;11.18,-42.21,;11.16,-43.75,;12.52,-41.46,;13.84,-42.24,;13.83,-43.78,;15.15,-44.57,;15.14,-46.1,;16.5,-43.81,)| Show InChI InChI=1S/C35H45Cl2N3O4/c1-33(2,3)15-13-28(22-7-9-23(10-8-22)31(43)38-18-14-29(41)42)40-32(44)30(24-19-26(36)21-27(37)20-24)39-35(40)16-11-25(12-17-35)34(4,5)6/h7-10,19-21,25,28H,11-18H2,1-6H3,(H,38,43)(H,41,42)/t25-,28-,35-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from GCGR in mouse liver membranes after 60 mins by scintillation counting analysis				J Med Chem 57: 2601-10 (2014) Article DOI: 10.1021/jm401858f BindingDB Entry DOI: 10.7270/Q20V8F9P
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075763 (4-[5-(4-Chloro-phenyl)-3-(2,6-dipropoxy-phenyl)-1H...) Show SMILES CCCOc1cccc(OCCC)c1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 |(9.36,4.01,;8.87,2.56,;7.36,2.26,;6.87,.79,;5.46,.18,;4.21,1.09,;2.81,.46,;2.64,-1.08,;3.88,-1.98,;3.72,-3.51,;2.32,-4.14,;1.07,-3.23,;-.34,-3.85,;5.28,-1.36,;6.53,-2.27,;7.99,-1.8,;8.9,-3.04,;7.99,-4.29,;6.52,-3.81,;5.27,-4.7,;3.93,-3.93,;2.6,-4.7,;2.6,-6.24,;3.95,-7.01,;5.27,-6.24,;10.43,-3.06,;11.18,-4.39,;12.72,-4.39,;13.51,-3.06,;15.05,-3.06,;12.74,-1.73,;11.2,-1.73,)| Show InChI InChI=1S/C27H27ClN2O2/c1-3-16-31-24-6-5-7-25(32-17-4-2)26(24)22-18-23(19-8-10-21(28)11-9-19)30-27(22)20-12-14-29-15-13-20/h5-15,18,30H,3-4,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair
Glucagon receptor (Mus musculus)	BDBM50075766 (4-[5-(4-Chloro-phenyl)-3-(2-propoxy-phenyl)-1H-pyr...) Show SMILES CCCOc1ccccc1-c1cc([nH]c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN2O/c1-2-15-28-23-6-4-3-5-20(23)21-16-22(17-7-9-19(25)10-8-17)27-24(21)18-11-13-26-14-12-18/h3-14,16,27H,2,15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity determined by reduction in binding of 125 I-glucagon to the human glucagon receptor expressed on CHO cells in absence of Mg+2				Bioorg Med Chem Lett 9: 641-6 (1999) BindingDB Entry DOI: 10.7270/Q2VD6XM1
					More data for this Ligand-Target Pair

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