Compile Data Set for Download or QSAR

Found 94 hits of ic50 for UniProtKB: P11344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Mus musculus (Mouse))	BDBM50044784 (CHEBI:79090 | SB-202190 | US10865384, Compound SB2...) Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50044784 (CHEBI:79090 | SB-202190 | US10865384, Compound SB2...) Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50045333 (CHEBI:90705 | SB-203580) Show SMILES C[S+]([O-])c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50045333 (CHEBI:90705 | SB-203580) Show SMILES C[S+]([O-])c1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50230001 (4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H13FN4O2/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(8-4-15)25(26)27/h1-12H,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50230001 (4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1 Show InChI InChI=1S/C20H13FN4O2/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(8-4-15)25(26)27/h1-12H,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50193667 (2,4,3',5'-tetrahydroxybibenzyl | CHEMBL221291) Show SMILES Oc1ccc(CCc2cc(O)cc(O)c2)c(O)c1 Show InChI InChI=1S/C14H14O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h3-8,15-18H,1-2H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50193667 (2,4,3',5'-tetrahydroxybibenzyl | CHEMBL221291) Show SMILES Oc1ccc(CCc2cc(O)cc(O)c2)c(O)c1 Show InChI InChI=1S/C14H14O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h3-8,15-18H,1-2H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237231 (CHEMBL4063130) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc2-[#8]-[#6](-[#6]-[#6](=O)-c2c1-[#8])-c1ccc(-[#8])c(-[#8])c1-[#6]\[#6]=[#6](\[#6])-[#6] Show InChI InChI=1S/C25H28O6/c1-13(2)5-7-16-15(9-10-18(26)24(16)29)21-12-20(28)23-22(31-21)11-19(27)17(25(23)30)8-6-14(3)4/h5-6,9-11,21,26-27,29-30H,7-8,12H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529600 (CHEMBL4445400) Show SMILES Oc1cccc(\C=C\c2ccc(O)cc2O)c1 Show InChI InChI=1S/C14H12O3/c15-12-3-1-2-10(8-12)4-5-11-6-7-13(16)9-14(11)17/h1-9,15-17H/b5-4+	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529600 (CHEMBL4445400) Show SMILES Oc1cccc(\C=C\c2ccc(O)cc2O)c1 Show InChI InChI=1S/C14H12O3/c15-12-3-1-2-10(8-12)4-5-11-6-7-13(16)9-14(11)17/h1-9,15-17H/b5-4+	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237232 (CHEMBL516671) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#8])c2-[#6](=O)-[#6]-[#6](-[#8]-c12)-c1cc(c(-[#8])cc1-[#8])C([#6])([#6])[#6]=[#6] Show InChI InChI=1S/C25H28O6/c1-6-25(4,5)16-9-15(18(27)10-19(16)28)22-12-21(30)23-20(29)11-17(26)14(24(23)31-22)8-7-13(2)3/h6-7,9-11,22,26-29H,1,8,12H2,2-5H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50108046 ((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...) Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)c(O)c1 Show InChI InChI=1S/C14H12O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h1-8,15-18H/b2-1+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50108046 ((oxyresveratrol)4-[(E)-2-(3,5-dihydroxyphenyl)viny...) Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)c(O)c1 Show InChI InChI=1S/C14H12O4/c15-11-4-3-10(14(18)8-11)2-1-9-5-12(16)7-13(17)6-9/h1-8,15-18H/b2-1+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50240041 (1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...) Show SMILES NC(=S)Nc1ccccc1 Show InChI InChI=1S/C7H8N2S/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of tyrosinase in alpha-MSH-induced mouse B16 cells				Bioorg Med Chem Lett 20: 4771-3 (2010) Article DOI: 10.1016/j.bmcl.2010.06.123 BindingDB Entry DOI: 10.7270/Q27M0BR0
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50251013 (2,4,2',4'-tetrahydroxy-3'-prenylchalcone | CHEMBL4...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])cc2-[#8])c1-[#8] Show InChI InChI=1S/C20H20O5/c1-12(2)3-7-15-18(23)10-8-16(20(15)25)17(22)9-5-13-4-6-14(21)11-19(13)24/h3-6,8-11,21,23-25H,7H2,1-2H3/b9-5+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50251013 (2,4,2',4'-tetrahydroxy-3'-prenylchalcone | CHEMBL4...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])cc2-[#8])c1-[#8] Show InChI InChI=1S/C20H20O5/c1-12(2)3-7-15-18(23)10-8-16(20(15)25)17(22)9-5-13-4-6-14(21)11-19(13)24/h3-6,8-11,21,23-25H,7H2,1-2H3/b9-5+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529589 (CHEMBL4239110) Show SMILES C\C(CO)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O Show InChI InChI=1S/C20H20O6/c1-12(11-21)2-6-15-18(24)9-7-16(20(15)26)17(23)8-4-13-3-5-14(22)10-19(13)25/h2-5,7-10,21-22,24-26H,6,11H2,1H3/b8-4+,12-2+	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529589 (CHEMBL4239110) Show SMILES C\C(CO)=C/Cc1c(O)ccc(C(=O)\C=C\c2ccc(O)cc2O)c1O Show InChI InChI=1S/C20H20O6/c1-12(11-21)2-6-15-18(24)9-7-16(20(15)26)17(23)8-4-13-3-5-14(22)10-19(13)25/h2-5,7-10,21-22,24-26H,6,11H2,1H3/b8-4+,12-2+	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50520909 (CHEMBL4461557) Show SMILES Oc1ccc(\C=C\C(=O)NCCCNC(=O)\C=C\c2ccc(O)cc2)cc1 Show InChI InChI=1S/C21H22N2O4/c24-18-8-2-16(3-9-18)6-12-20(26)22-14-1-15-23-21(27)13-7-17-4-10-19(25)11-5-17/h2-13,24-25H,1,14-15H2,(H,22,26)(H,23,27)/b12-6+,13-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16-F1 cells				Bioorg Med Chem 26: 6015-6022 (2018) Article DOI: 10.1016/j.bmc.2018.10.036 BindingDB Entry DOI: 10.7270/Q2SN0DC6
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237229 (CHEMBL4083227) Show SMILES [#6]-[#8]-c1cc(-[#8])c(cc1-[#6]-1-[#6]-[#6](=O)-c2c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc2-[#8]-1)C([#6])([#6])[#6]=[#6] Show InChI InChI=1S/C26H30O6/c1-7-26(4,5)17-10-16(21(31-6)12-19(17)28)22-13-20(29)24-23(32-22)11-18(27)15(25(24)30)9-8-14(2)3/h7-8,10-12,22,27-28,30H,1,9,13H2,2-6H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50203985 ((E)-1-(2,4-dihydroxyphenyl)-3-(2,4-dihydroxyphenyl...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C15H12O5/c16-10-3-1-9(14(19)7-10)2-6-13(18)12-5-4-11(17)8-15(12)20/h1-8,16-17,19-20H/b6-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50203985 ((E)-1-(2,4-dihydroxyphenyl)-3-(2,4-dihydroxyphenyl...) Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C15H12O5/c16-10-3-1-9(14(19)7-10)2-6-13(18)12-5-4-11(17)8-15(12)20/h1-8,16-17,19-20H/b6-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hr				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50237230 (CHEMBL4101226) Show SMILES [#6]-[#8]-c1cc(-[#8])c(cc1-[#6]-1-[#6]-[#6](=O)-c2c(-[#8])cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2-[#8]-1)C([#6])([#6])[#6]=[#6] Show InChI InChI=1S/C26H30O6/c1-7-26(4,5)17-10-16(22(31-6)12-19(17)28)23-13-21(30)24-20(29)11-18(27)15(25(24)32-23)9-8-14(2)3/h7-8,10-12,23,27-29H,1,9,13H2,2-6H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin production measured after 24 hrs				Bioorg Med Chem Lett 27: 1789-1794 (2017) Article DOI: 10.1016/j.bmcl.2017.02.058 BindingDB Entry DOI: 10.7270/Q2MW2KDB
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175278 ((E)-2,3-bis(4-Hydroxyphenyl)acrylonitrile (21)) Show SMILES Oc1ccc(\C=C(\C#N)c2ccc(O)cc2)cc1 Show InChI InChI=1S/C15H11NO2/c16-10-13(12-3-7-15(18)8-4-12)9-11-1-5-14(17)6-2-11/h1-9,17-18H/b13-9-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.06E+3	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50095997 (3',4',7-trihydroxyisoflavone | CHEMBL13486) Show SMILES Oc1ccc2c(c1)occ(-c1ccc(O)c(O)c1)c2=O Show InChI InChI=1S/C15H10O5/c16-9-2-3-10-14(6-9)20-7-11(15(10)19)8-1-4-12(17)13(18)5-8/h1-7,16-18H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific Corporation Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse Melan-a cells by ELISA				Bioorg Med Chem Lett 20: 1162-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.021 BindingDB Entry DOI: 10.7270/Q2M045JZ
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529588 (Bisabolangelone) Show SMILES [H][C@@]12[#6]-[#6](-[#6])=[#6]-[#6](=O)[C@]1([H])[C@]([#6])([#8])\[#6](-[#8]2)=[#6]\[#6]=[#6](\[#6])-[#6] |r,c:4| Show InChI InChI=1S/C15H20O3/c1-9(2)5-6-13-15(4,17)14-11(16)7-10(3)8-12(14)18-13/h5-7,12,14,17H,8H2,1-4H3/b13-6-/t12-,14+,15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in alpha-MSH induced melanin synthesis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50529588 (Bisabolangelone) Show SMILES [H][C@@]12[#6]-[#6](-[#6])=[#6]-[#6](=O)[C@]1([H])[C@]([#6])([#8])\[#6](-[#8]2)=[#6]\[#6]=[#6](\[#6])-[#6] |r,c:4| Show InChI InChI=1S/C15H20O3/c1-9(2)5-6-13-15(4,17)14-11(16)7-10(3)8-12(14)18-13/h5-7,12,14,17H,8H2,1-4H3/b13-6-/t12-,14+,15-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16 cells assessed as reduction in alpha-MSH induced melanin synthesis				J Med Chem 61: 7395-7418 (2018) Article DOI: 10.1021/acs.jmedchem.7b00967 BindingDB Entry DOI: 10.7270/Q2CN77C2
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM23926 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1 Show InChI InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50209568 (4',7,8-trihydroxyisoflavone | 7,8,4'-trihydroxyiso...) Show SMILES Oc1ccc(cc1)-c1coc2c(O)c(O)ccc2c1=O Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-15-10(13(11)18)5-6-12(17)14(15)19/h1-7,16-17,19H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific Corporation Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse Melan-a cells by ELISA				Bioorg Med Chem Lett 20: 1162-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.021 BindingDB Entry DOI: 10.7270/Q2M045JZ
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175269 (Trans-4-Styryl-phenol (8)) Show SMILES Oc1ccc(\C=C/c2ccccc2)cc1 Show InChI InChI=1S/C14H12O/c15-14-10-8-13(9-11-14)7-6-12-4-2-1-3-5-12/h1-11,15H/b7-6-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50521808 (CHEMBL4462424) Show SMILES COc1cc(O)c(C(=O)\C=C\c2ccccc2)c(O)c1C Show InChI InChI=1S/C17H16O4/c1-11-15(21-2)10-14(19)16(17(11)20)13(18)9-8-12-6-4-3-5-7-12/h3-10,19-20H,1-2H3/b9-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F0 cells assessed as reduction in melanin production incubated for 24 hrs by spectrophotometric analysis				Bioorg Med Chem 27: 3722-3728 (2019) Article DOI: 10.1016/j.bmc.2019.06.041 BindingDB Entry DOI: 10.7270/Q2D22212
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50296247 (3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxyindol-3-yl)...) Show SMILES Oc1ccc2[nH]cc(CCNC(=O)\C=C\c3ccc(O)c(O)c3)c2c1 Show InChI InChI=1S/C19H18N2O4/c22-14-3-4-16-15(10-14)13(11-21-16)7-8-20-19(25)6-2-12-1-5-17(23)18(24)9-12/h1-6,9-11,21-24H,7-8H2,(H,20,25)/b6-2+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL					Assay Description Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation				Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50521808 (CHEMBL4462424) Show SMILES COc1cc(O)c(C(=O)\C=C\c2ccccc2)c(O)c1C Show InChI InChI=1S/C17H16O4/c1-11-15(21-2)10-14(19)16(17(11)20)13(18)9-8-12-6-4-3-5-7-12/h3-10,19-20H,1-2H3/b9-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Nacional de C£rdoba Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16F0 cells using L-DOPA as substrate by UV-Visible spectrophotometric analysis				Bioorg Med Chem 27: 3722-3728 (2019) Article DOI: 10.1016/j.bmc.2019.06.041 BindingDB Entry DOI: 10.7270/Q2D22212
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside | Arbutin |...) Show SMILES OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific Corporation Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse Melan-a cells by ELISA				Bioorg Med Chem Lett 20: 1162-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.021 BindingDB Entry DOI: 10.7270/Q2M045JZ
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50520917 (CHEMBL4450699) Show SMILES Oc1cccc(\C=C\C(=O)NCCCNC(=O)\C=C\c2cccc(O)c2)c1 Show InChI InChI=1S/C21H22N2O4/c24-18-6-1-4-16(14-18)8-10-20(26)22-12-3-13-23-21(27)11-9-17-5-2-7-19(25)15-17/h1-2,4-11,14-15,24-25H,3,12-13H2,(H,22,26)(H,23,27)/b10-8+,11-9+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16-F1 cells				Bioorg Med Chem 26: 6015-6022 (2018) Article DOI: 10.1016/j.bmc.2018.10.036 BindingDB Entry DOI: 10.7270/Q2SN0DC6
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50296244 (2,4-dihydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)...) Show SMILES Oc1ccc(C(=O)NCCc2c[nH]c3ccc(O)cc23)c(O)c1 Show InChI InChI=1S/C17H16N2O4/c20-11-2-4-15-14(7-11)10(9-19-15)5-6-18-17(23)13-3-1-12(21)8-16(13)22/h1-4,7-9,19-22H,5-6H2,(H,18,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL					Assay Description Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation				Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50520915 (CHEMBL4544904) Show SMILES COc1ccc(\C=C\C(=O)NCCCNC(=O)\C=C\c2ccc(OC)c(O)c2)cc1O Show InChI InChI=1S/C23H26N2O6/c1-30-20-8-4-16(14-18(20)26)6-10-22(28)24-12-3-13-25-23(29)11-7-17-5-9-21(31-2)19(27)15-17/h4-11,14-15,26-27H,3,12-13H2,1-2H3,(H,24,28)(H,25,29)/b10-6+,11-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16-F1 cells				Bioorg Med Chem 26: 6015-6022 (2018) Article DOI: 10.1016/j.bmc.2018.10.036 BindingDB Entry DOI: 10.7270/Q2SN0DC6
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175267 (Trans-4-Styrylbenzonitrile (6)) Show SMILES N#Cc1ccc(\C=C/c2ccccc2)cc1 Show InChI InChI=1S/C15H11N/c16-12-15-10-8-14(9-11-15)7-6-13-4-2-1-3-5-13/h1-11H/b7-6-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175271 (Trans-1-fluoro-4-(4-methoxystyryl)benzene (10)) Show SMILES COc1ccc(\C=C/c2ccc(F)cc2)cc1 Show InChI InChI=1S/C15H13FO/c1-17-15-10-6-13(7-11-15)3-2-12-4-8-14(16)9-5-12/h2-11H,1H3/b3-2-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50342164 (5-(3-Chlorobenzyloxy)benzene-1,3-diol | CHEMBL1766...) Show SMILES Oc1cc(O)cc(OCc2cccc(Cl)c2)c1 Show InChI InChI=1S/C13H11ClO3/c14-10-3-1-2-9(4-10)8-17-13-6-11(15)5-12(16)7-13/h1-7,15-16H,8H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of Daegu Curated by ChEMBL					Assay Description Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrate				Bioorg Med Chem 19: 2168-75 (2011) Article DOI: 10.1016/j.bmc.2011.02.044 BindingDB Entry DOI: 10.7270/Q2K937TS
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175272 (Trans-2-Bromo-1-methoxy-4-styryl-benzene (11)) Show SMILES COc1ccc(\C=C/c2ccccc2)cc1Br Show InChI InChI=1S/C15H13BrO/c1-17-15-10-9-13(11-14(15)16)8-7-12-5-3-2-4-6-12/h2-11H,1H3/b8-7-	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.62E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL					Assay Description Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation				Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50520911 (CHEMBL4544938) Show SMILES COc1cc(\C=C\C(=O)NCCCNC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O Show InChI InChI=1S/C23H26N2O6/c1-30-20-14-16(4-8-18(20)26)6-10-22(28)24-12-3-13-25-23(29)11-7-17-5-9-19(27)21(15-17)31-2/h4-11,14-15,26-27H,3,12-13H2,1-2H3,(H,24,28)(H,25,29)/b10-6+,11-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16-F1 cells				Bioorg Med Chem 26: 6015-6022 (2018) Article DOI: 10.1016/j.bmc.2018.10.036 BindingDB Entry DOI: 10.7270/Q2SN0DC6
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50342165 (5-(3,4-Dichlorobenzyloxy)benzene-1,3-diol | CHEMBL...) Show SMILES Oc1cc(O)cc(OCc2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C13H10Cl2O3/c14-12-2-1-8(3-13(12)15)7-18-11-5-9(16)4-10(17)6-11/h1-6,16-17H,7H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Catholic University of Daegu Curated by ChEMBL					Assay Description Inhibition of tyrosinase activity in alpha-MSH-stimulated mouse B16 cells using L-tyrosine as substrate				Bioorg Med Chem 19: 2168-75 (2011) Article DOI: 10.1016/j.bmc.2011.02.044 BindingDB Entry DOI: 10.7270/Q2K937TS
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM32212 (1H-indol-5-ol | cid_16054) Show SMILES Oc1ccc2[nH]ccc2c1 Show InChI InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL					Assay Description Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation				Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50296245 (3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benz...) Show SMILES Oc1ccc2[nH]cc(CCNC(=O)c3ccc(O)c(O)c3)c2c1 Show InChI InChI=1S/C17H16N2O4/c20-12-2-3-14-13(8-12)11(9-19-14)5-6-18-17(23)10-1-4-15(21)16(22)7-10/h1-4,7-9,19-22H,5-6H2,(H,18,23)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Advanced Industrial Science and Technology Curated by ChEMBL					Assay Description Inhibition of catecholase activity of tyrosinase in mouse B16 cells assessed as dopachrome formation				Bioorg Med Chem Lett 19: 4178-82 (2009) Article DOI: 10.1016/j.bmcl.2009.05.115 BindingDB Entry DOI: 10.7270/Q2BR8S70
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM175263 (Trans-1-Fluoro-4-styryl-benzene (2)) Show SMILES Fc1ccc(\C=C/c2ccccc2)cc1 Show InChI InChI=1S/C14H11F/c15-14-10-8-13(9-11-14)7-6-12-4-2-1-3-5-12/h1-11H/b7-6-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.94E+4	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
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Tyrosinase (Mus musculus (Mouse))	BDBM50219502 (4-hydroxyphenyl beta-D-glucopyranoside | Arbutin |...) Show SMILES OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16-F1 cells				Bioorg Med Chem 26: 6015-6022 (2018) Article DOI: 10.1016/j.bmc.2018.10.036 BindingDB Entry DOI: 10.7270/Q2SN0DC6
					More data for this Ligand-Target Pair
Tyrosinase (Mus musculus (Mouse))	BDBM50520916 (TERRESTRIBISAMIDE) Show SMILES COc1cc(\C=C\C(=O)NCCCCNC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O Show InChI InChI=1S/C24H28N2O6/c1-31-21-15-17(5-9-19(21)27)7-11-23(29)25-13-3-4-14-26-24(30)12-8-18-6-10-20(28)22(16-18)32-2/h5-12,15-16,27-28H,3-4,13-14H2,1-2H3,(H,25,29)(H,26,30)/b11-7+,12-8+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of tyrosinase in mouse B16-F1 cells				Bioorg Med Chem 26: 6015-6022 (2018) Article DOI: 10.1016/j.bmc.2018.10.036 BindingDB Entry DOI: 10.7270/Q2SN0DC6
					More data for this Ligand-Target Pair

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