Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332053![]() (US10189854, Compound 1 | [1-[5-(2-Fluorophenyl)-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332054![]() (1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-N,N-dimethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332055![]() (US10189854, Compound 3 | [1-[5-(1-Fluorophenyl)-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332056![]() (4-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-spiro[1,2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332057![]() (US10189854, Compound 5 | [1-[5-(2-Fluorophenyl)-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332059![]() (Morpholin-4-yl-[1-(5-phenyl-pyrimidin-2-yl)-spiro[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332060![]() (US10189854, Compound 8 | [1-[5-(2,4-Difluoro-pheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332062![]() (Morpholin-4-yl-[1-(5-o-tolyl-pyrimidin-2-yl)-spiro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332063![]() (US10189854, Compound 15 | [1-[5-(2,3-Difluoro-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332064![]() (US10189854, Compound 16 | [1-[5-(2-Fluoro-5-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332065![]() (US10189854, Compound 17 | [1-[5-(2-Fluoro-4-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332070![]() (4-Fluoro-3-[2-[6-(morpholine-4-carbonyl)-spiro[1,2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332071![]() (US10189854, Compound 23 | [1-[5-[2-Fluoro-5-(trifl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332074![]() (3-Fluoro-4-[2-[6-(morpholine-4-carbonyl)-spiro[1,2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332075![]() (US10189854, Compound 27 | [1-[5-(2,6-Difluoro-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332077![]() (US10189854, Compound 29 | [1-[5-(2-Fluoro-4-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332079![]() (US10189854, Compound 31 | [1-[5-(2-Methoxyphenyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332081![]() (US10189854, Compound 34 | US10189854, Compound 94 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332082![]() (4-Fluoro-3-[2-[6-(morpholine-4-carbonyl)-spiro[1,2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332084![]() (4-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]spiro[1,2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332086![]() (US10189854, Compound 40 | [(3R)-3-Amino-pyrrolidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332087![]() (N-(2-Amino-ethyl)-1-[5-(2-fluorophenyl)-pyrimidin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332088![]() (US10189854, Compound 42 | [1-[5-(2-Fluoro-5-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332089![]() (US10189854, Compound 43 | [1-[5-(4-Fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332090![]() (US10189854, Compound 44 | [1-[5-(2-Fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332094![]() (US10189854, Compound 48 | [1-[5-(3-Methoxyphenyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332095![]() (US10189854, Compound 49 | [1-(5-Phenyl-pyrimidin-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332096![]() (US10189854, Compound 50 | [1-[5-(3,5-Difluoro-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332098![]() (US10189854, Compound 52 | [1-[5-(2-Fluoro-5-methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332100![]() (3-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332101![]() (4-[1-(5-Phenyl-pyrimidin-2-yl)-spiro[1,2-dihydro-i...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332102![]() (3-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332103![]() (US10189854, Compound 57 | [1-[5-(3-Fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332104![]() (US10189854, Compound 58 | [1-[5-(5-Chloro-2-fluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332105![]() (US10189854, Compound 59 | [1-(5-Phenyl-pyrimidin-2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332106![]() (US10189854, Compound 60 | [1-[5-(2-Fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332109![]() (4-[2-[6-(Morpholine-4-carbonyl)-spiro[1,2-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332111![]() (3-Fluoro-N,N-dimethyl-4-[2-[6-(morpholine-4-carbon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332118![]() (US10189854, Compound 72 | [1-[5-[2-Fluoro-5-(trifl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332119![]() (US10189854, Compound 73 | [1-[5-(2-Fluoro-5-methox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332128![]() (US10189854, Compound 84 | [1-[5-(2-Fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332129![]() (1-[5-[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-spiro[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332137![]() (US10189854, Compound 93 | [1-[5-(2-Fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332081![]() (US10189854, Compound 34 | US10189854, Compound 94 ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332139![]() (1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-N-(2-hydroxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332140![]() (US10189854, Compound 96 | [1-[5-(2-Fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332143![]() (N-[2-(Dimethylamino)ethyl]-1-[5-(2-fluorophenyl)-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332147![]() (US10189854, Compound 103 | [1-[5-(2-Fluorophenyl)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332148![]() (US10189854, Compound 104 | [(2R,6S)-2,6-dimethyl-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM332151![]() ((2,5-Diazabicyclo[2.2.1]heptan-2-yl)-[1-[5-(2-fluo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
GRUENENTHAL GMBH US Patent | Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ... | US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4 | |||||||||||
More data for this Ligand-Target Pair |
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