Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM60588 (3-(3-fluoro-4-{[2-(pyridin-3-yl)-1H-pyrrolo[2,3-b]...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM60589 (6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM50306682 ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 7.67 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM60587 (3-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM60590 (6-(1-{6-phenyl-[1,2,4]triazolo[4,3-b][1,2,4]triazi...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM50306682 ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 13.7 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM179803 (3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 14.6 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50306682 ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 17.3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM179803 (3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 17.6 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM179801 (3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22.8 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM179802 (3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 47.4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM179804 (3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 51.2 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM179800 (3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM60586 (4-(4-{3-[1-(2,6-dichloro-3-fluorophenyl)ethyl]-1H-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM179803 (3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 133 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM179801 (3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 135 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM50306682 ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 188 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM179800 (3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 214 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM179798 (3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 286 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM179803 (3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(pi...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 337 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM179804 (3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 372 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM179798 (3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 504 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM179802 (3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 508 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM179801 (3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 578 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM179801 (3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 651 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM179800 (3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 725 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM179802 (3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 735 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Isoform 2 of Hepatocyte growth factor receptor (2) (Homo sapiens (Human)) | BDBM179799 (4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 982 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Tianjin University of Science and Technology | Assay Description The c-Met kinase activity of five target compounds and three positive compounds were evaluated using standard Z-LYTE Assays (fluorescence resonance e... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM179800 (3-((2,6-dichloro-3-fluorophenyl)sulfide)-5-(1-(pip...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM179798 (3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM179798 (3-(1-(2,6-dichloro-3-fluorophenyl)ethyl)-2-methyl-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM179804 (3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM179799 (4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.71E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM179804 (3-{[1-(2,6-dichloro-3-fluorophenyl)ethyl]sulfanyl}...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.81E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM179802 (3-(1-(2,6-dichloro-3-fluorophenyl)cyclopropyl)-5-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.99E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [L1196M] (Homo sapiens (Human)) | BDBM179799 (4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.31E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor [C1156Y] (Homo sapiens (Human)) | BDBM179799 (4-(4-{2-chloro-3-[1-(2,6-dichloro-3-fluorophenyl)e...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.08E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Tianjin University of Science and Technology | Assay Description The ALK kinase activity of five target compounds and three positive compounds were evaluated using standard homogeneous time-resolved fluorescence (H... | Bioorg Chem 65: 146-58 (2016) Article DOI: 10.1016/j.bioorg.2016.02.009 BindingDB Entry DOI: 10.7270/Q2VT1QVX | |||||||||||
More data for this Ligand-Target Pair |