Compile Data Set for Download or QSAR

Found 34 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50011238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368543 (1-(piperidin-1-yl)-N-(1H- pyrazolo[4,3-b]pyridin-3...) Show SMILES C1CCN(CC1)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C20H20N6/c1-2-11-26(12-3-1)20-16-7-6-15(13-14(16)8-10-22-20)23-19-18-17(24-25-19)5-4-9-21-18/h4-10,13H,1-3,11-12H2,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	215	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50148386 (CHEMBL4745063) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2cnccc2n1 Show InChI InChI=1S/C21H23N3O4S2/c1-24-12-17(13-4-3-5-15(10-13)28-2)19-16(21(24)25)11-18(29-19)20(22)23-14-6-8-30(26,27)9-7-14/h3-5,10-12,14H,6-9H2,1-2H3,(H2,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078632 (CHEMBL4751992) Show SMILES C1CCN(C1)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C21H18N6/c1-16-14-27(25-24-16)12-11-26-15-23-20(18-5-3-2-4-6-18)21(26)19-9-7-17(13-22)8-10-19/h2-10,14-15H,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Evaluated for the percent binding affinity against H1 receptor by an H1 histamine-mediated bronchospasm				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078633 (CHEMBL4761011) Show SMILES C1CC(C1)Nc1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C19H17N7/c1-24-10-15(8-22-24)11-26-13-21-18(17-9-23-25(2)12-17)19(26)16-5-3-14(7-20)4-6-16/h3-6,8-10,12-13H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	869	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-Ro-15-4513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cells				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078634 (CHEMBL4743261) Show SMILES C(Nc1nccc2cc(Nc3n[nH]c4cccnc34)ccc12)c1ccccc1 Show InChI InChI=1S/C17H16N8O2/c1-12-8-24(21-20-12)11-23-10-18-16(14-7-19-22(2)9-14)17(23)13-3-5-15(6-4-13)25(26)27/h3-10H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-Ro-15-4513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cells				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368541 (N1,N1-diethyl-N6-(1H- pyrazolo[4,3-b]pyridin-3- yl...) Show SMILES CCN(CC)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C19H20N6/c1-3-25(4-2)19-15-8-7-14(12-13(15)9-11-21-19)22-18-17-16(23-24-18)6-5-10-20-17/h5-12H,3-4H2,1-2H3,(H2,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	164	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078635 (CHEMBL4797966 | US11242342, Compound 23) Show SMILES COCCNc1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C18H15FN8/c1-12-8-27(24-23-12)11-26-10-21-17(15-7-22-25(2)9-15)18(26)13-3-4-14(6-20)16(19)5-13/h3-5,7-10H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	121	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368531 (N-(1H-pyrazolo[4,3-b] pyridin-3-yl)-1-(2- (trifluo...) Show SMILES FC(F)(F)C1CCCCN1c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	306	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368537 (1-(3,3-difluoropyrrolidin- 1-yl)-N-(1H- pyrazolo[4...) Show SMILES FC1(F)CCN(C1)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C19H16F2N6/c20-19(21)6-9-27(11-19)18-14-4-3-13(10-12(14)5-8-23-18)24-17-16-15(25-26-17)2-1-7-22-16/h1-5,7-8,10H,6,9,11H2,(H2,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	249	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368542 (1-(1H-pyrazol-1-yl)-N- (1H- pyrazolo[4,3-b]pyridin...) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2c(nccc2c1)-n1cccn1 Show InChI InChI=1S/C18H13N7/c1-3-15-16(19-7-1)17(24-23-15)22-13-4-5-14-12(11-13)6-9-20-18(14)25-10-2-8-21-25/h1-11H,(H2,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078636 (CHEMBL4782314) Show SMILES Cc1ccn(n1)-c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C18H15FN8/c1-12-8-27(24-23-12)11-26-10-21-17(14-7-22-25(2)9-14)18(26)15-4-3-13(6-20)5-16(15)19/h3-5,7-10H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	237	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368521 (1-(3,5-dimethyl-1H- pyrazol-1-yl)-N- (1H-pyrazolo[...) Show SMILES Cc1cc(C)n(n1)-c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C20H17N7/c1-12-10-13(2)27(26-12)20-16-6-5-15(11-14(16)7-9-22-20)23-19-18-17(24-25-19)4-3-8-21-18/h3-11H,1-2H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	726	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368549 (1-ethyl-N-(1H-pyrazolo [4,3-b]pyridin- 3-yl)isoqui...) Show SMILES CCc1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C17H15N5/c1-2-14-13-6-5-12(10-11(13)7-9-18-14)20-17-16-15(21-22-17)4-3-8-19-16/h3-10H,2H2,1H3,(H2,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368548 (1-cyclopropyl-N-(1H- pyrazolo[4,3-b]pyridin-3- yl)...) Show SMILES C1CC1c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C18H15N5/c1-2-15-17(19-8-1)18(23-22-15)21-13-5-6-14-12(10-13)7-9-20-16(14)11-3-4-11/h1-2,5-11H,3-4H2,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368526 (1-(difluoromethyl)-N- (1H-pyrazolo [4,3-b]pyridin-...) Show SMILES FC(F)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C16H11F2N5/c17-15(18)13-11-4-3-10(8-9(11)5-7-20-13)21-16-14-12(22-23-16)2-1-6-19-14/h1-8,15H,(H2,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368518 (N-(1H-pyrazolo[4,3-b] pyridin-3-yl)-1-(1,1,1- trif...) Show SMILES CC(c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368512 (1-(1-methyl-1H-pyrazol- 5-yl)-N-(1H-pyrazolo [4,3-...) Show SMILES Cn1nccc1-c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C19H15N7/c1-26-16(7-10-22-26)17-14-5-4-13(11-12(14)6-9-21-17)23-19-18-15(24-25-19)3-2-8-20-18/h2-11H,1H3,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368511 (1-(1-methyl-3- (trifluoromethyl)-1H- pyrazol-5-yl)...) Show SMILES Cn1nc(cc1-c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12)C(F)(F)F Show InChI InChI=1S/C20H14F3N7/c1-30-15(10-16(29-30)20(21,22)23)17-13-5-4-12(9-11(13)6-8-25-17)26-19-18-14(27-28-19)3-2-7-24-18/h2-10H,1H3,(H2,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078637 (CHEMBL4784617) Show SMILES O=c1[nH]ccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C15H13N5/c1-19-10-17-14(13-8-18-20(2)9-13)15(19)12-5-3-11(7-16)4-6-12/h3-6,8-10H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	264	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078638 (CHEMBL4764520) Show SMILES Cn1ccc2cc(Nc3n[nH]c4cccnc34)ccc2c1=O Show InChI InChI=1S/C19H18N8/c1-14-11-27(24-23-14)8-7-26-13-21-18(17-10-22-25(2)12-17)19(26)16-5-3-15(9-20)4-6-16/h3-6,10-13H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078639 (CHEMBL4762098) Show SMILES CC(C)Cn1ccc2cc(Nc3n[nH]c4cccnc34)ccc2c1=O Show InChI InChI=1S/C15H14N6/c1-12-10-21(19-18-12)7-6-20-11-17-9-15(20)14-4-2-13(8-16)3-5-14/h2-5,9-11H,6-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	685	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078640 (CHEMBL4755785) Show SMILES O=c1n(CC2CCC2)ccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C19H17N7O/c1-13-9-17(27-23-13)18-19(16-5-3-15(10-20)4-6-16)25(12-21-18)7-8-26-11-14(2)22-24-26/h3-6,9,11-12H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	653	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50078641 (CHEMBL4750744) Show SMILES O=c1n(ccc2cc(Nc3n[nH]c4cccnc34)ccc12)C1CCCC1 Show InChI InChI=1S/C18H15N7S/c1-13-10-25(23-22-13)7-6-24-11-21-17(16-9-20-12-26-16)18(24)15-4-2-14(8-19)3-5-15/h2-5,9-12H,6-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368520 (N-(1H-pyrazolo[4,3-b] pyridin-3-yl)-1- (trifluorom...) Show SMILES FC(F)(F)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C16H10F3N5/c17-16(18,19)14-11-4-3-10(8-9(11)5-7-21-14)22-15-13-12(23-24-15)2-1-6-20-13/h1-8H,(H2,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368515 (N-(1H-pyrazolo[3,4- b]pyrazin-3-yl)-1- (trifluorom...) Show SMILES FC(F)(F)c1nccc2cc(Nc3n[nH]c4nccnc34)ccc12 Show InChI InChI=1S/C15H9F3N6/c16-15(17,18)12-10-2-1-9(7-8(10)3-4-20-12)22-14-11-13(23-24-14)21-6-5-19-11/h1-7H,(H2,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	51	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368514 (N-(1H-pyrazolo[3,4-b] pyridin-3-yl)-1- (trifluorom...) Show SMILES FC(F)(F)c1nccc2cc(Nc3n[nH]c4ncccc34)ccc12 Show InChI InChI=1S/C16H10F3N5/c17-16(18,19)13-11-4-3-10(8-9(11)5-7-20-13)22-15-12-2-1-6-21-14(12)23-24-15/h1-8H,(H2,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368553 (N-(naphthalen-2-yl)-1H- pyrazolo[4,3-b]pyridin-3- ...) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2ccccc2c1 Show InChI InChI=1S/C16H12N4/c1-2-5-12-10-13(8-7-11(12)4-1)18-16-15-14(19-20-16)6-3-9-17-15/h1-10H,(H2,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	403	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM368552 (N-(1H-pyrazolo[4,3-b] pyridin- 3-yl)isoquinolin-6-...) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2cnccc2c1 Show InChI InChI=1S/C15H11N5/c1-2-13-14(17-6-1)15(20-19-13)18-12-4-3-11-9-16-7-5-10(11)8-12/h1-9H,(H2,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50147621 (CHEMBL4788007) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2ncccc2c1 Show InChI InChI=1S/C22H25N3O6S2/c1-23-13-16(14-5-6-17(30-2)18(11-14)31-3)20-15(21(23)26)12-19(32-20)22(27)24-7-9-25(10-8-24)33(4,28)29/h5-6,11-13H,7-10H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	732	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50148372 (CHEMBL4795205) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2nccnc2c1 Show InChI InChI=1S/C19H20N2O4S/c1-20(2)19(23)16-9-12-17(26-16)13(10-21(3)18(12)22)11-6-7-14(24-4)15(8-11)25-5/h6-10H,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50148374 (CHEMBL4760038) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2ccncc2c1 Show InChI InChI=1S/C22H24N2O4S/c1-23-13-16(14-7-8-17(27-2)18(11-14)28-3)20-15(21(23)25)12-19(29-20)22(26)24-9-5-4-6-10-24/h7-8,11-13H,4-6,9-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50148375 (CHEMBL4800673) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2cccnc2c1 Show InChI InChI=1S/C21H20N4O3S2/c1-25-12-17(14-4-2-3-13(9-14)11-22)19-16(21(25)26)10-18(29-19)20(23)24-15-5-7-30(27,28)8-6-15/h2-4,9-10,12,15H,5-8H2,1H3,(H2,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50148385 (CHEMBL4753444) Show SMILES N(c1n[nH]c2cccnc12)c1ccc2ncncc2c1 Show InChI InChI=1S/C21H20F3N3O3S2/c1-27-11-16(12-3-2-4-13(9-12)21(22,23)24)18-15(20(27)28)10-17(31-18)19(25)26-14-5-7-32(29,30)8-6-14/h2-4,9-11,14H,5-8H2,1H3,(H2,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50017937 (CHEMBL4751941) Show SMILES CN1CCN(CC1)c1nccc2cc(Nc3n[nH]c4cccnc34)ccc12 Show InChI InChI=1S/C27H27N5O5/c28-24(29)16-1-5-20(6-2-16)36-22-13-19(26(33)32-11-9-18(10-12-32)27(34)35)14-23(15-22)37-21-7-3-17(4-8-21)25(30)31/h1-8,13-15,18H,9-12H2,(H3,28,29)(H3,30,31)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [3H]-Nalpha-methylhistamine binding to H3 receptor in guinea-pig brain membranes				Citation and Details Article DOI: 10.1016/j.bmcl.2018.10.050 BindingDB Entry DOI: 10.7270/Q2MG7T2H
					More data for this Ligand-Target Pair