Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholinesterase (Homo sapiens (Human)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri St. Louis Curated by ChEMBL | Assay Description Inhibition of human BChE using butyrylthiocholine as substrate measured for 30 secs by Ellman's method | Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Missouri St. Louis Curated by ChEMBL | Assay Description Inhibition of human AChE using p-nitrophenyl acetate as substrate measured for 30 secs by spectrophotometric analysis | Bioorg Med Chem 25: 3053-3058 (2017) Article DOI: 10.1016/j.bmc.2017.03.058 BindingDB Entry DOI: 10.7270/Q2H70J09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Mus musculus (mouse)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Displacement of acetylcholine from AChE in Swiss Webster mouse brain after 5 mins | Nat Chem Biol 4: 373-8 (2008) Article DOI: 10.1038/nchembio.86 BindingDB Entry DOI: 10.7270/Q2SX6DF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration method | Bioorg Med Chem Lett 20: 6208-12 (2010) Article DOI: 10.1016/j.bmcl.2010.08.110 BindingDB Entry DOI: 10.7270/Q24X581T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 338 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration method | Bioorg Med Chem Lett 20: 6208-12 (2010) Article DOI: 10.1016/j.bmcl.2010.08.110 BindingDB Entry DOI: 10.7270/Q24X581T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Mus musculus (mouse)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of FAAH-mediated [3H]anadamide hydrolysis in mouse brain | Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 13 (Mus musculus (mouse)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of esterase activity of mouse carbonic anhydrase 13 by CO2 hydration method | Bioorg Med Chem Lett 20: 6208-12 (2010) Article DOI: 10.1016/j.bmcl.2010.08.110 BindingDB Entry DOI: 10.7270/Q24X581T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Mus musculus (mouse)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 mins | Nat Chem Biol 4: 373-8 (2008) Article DOI: 10.1038/nchembio.86 BindingDB Entry DOI: 10.7270/Q2SX6DF4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Mus musculus (Mouse)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Displacement of [3H]CP55940 from CB1 receptor in mouse brain | Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Mus musculus (mouse)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain | Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Mus musculus (mouse)) | BDBM50240416 (CHEMBL23838 | O,O-diethyl O-p-nitrophenyl phosphat...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Displacement of [3H]anandamide from FAAH in Swiss Webster mouse brain after 5 mins | Nat Chem Biol 4: 373-8 (2008) Article DOI: 10.1038/nchembio.86 BindingDB Entry DOI: 10.7270/Q2SX6DF4 | |||||||||||
More data for this Ligand-Target Pair |