Found 608 hits of ki for UniProtKB: P35218 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341394
(CHEMBL4171921)Show SMILES [#6]-[#6]-[#6]-[#6]-[#6][Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C11H17NO2SSe/c1-2-3-4-9-16-11-7-5-10(6-8-11)15(12,13)14/h5-8H,2-4,9H2,1H3,(H2,12,13,14) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341391
(CHEMBL4163634)Show SMILES [#6]-[#8]-[#6]-[#6][Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO3SSe/c1-13-6-7-15-9-4-2-8(3-5-9)14(10,11)12/h2-5H,6-7H2,1H3,(H2,10,11,12) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341388
(CHEMBL4159208)Show SMILES [#7]S(=O)(=O)c1ccc([Se;v2][#6]-[#6]-c2ccccc2)cc1 Show InChI InChI=1S/C14H15NO2SSe/c15-18(16,17)13-6-8-14(9-7-13)19-11-10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H2,15,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341390
(CHEMBL4161665)Show SMILES [#7]S(=O)(=O)c1ccc(-[#6][Se;v2]c2ccccc2)cc1 Show InChI InChI=1S/C13H13NO2SSe/c14-17(15,16)12-8-6-11(7-9-12)10-18-13-4-2-1-3-5-13/h1-9H,10H2,(H2,14,15,16) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341396
(CHEMBL4176433)Show SMILES [#7]S(=O)(=O)c1ccc([Se;v2][#6]-[#6]-[#8])cc1 Show InChI InChI=1S/C8H11NO3SSe/c9-13(11,12)7-1-3-8(4-2-7)14-6-5-10/h1-4,10H,5-6H2,(H2,9,11,12) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341395
(CHEMBL4175369)Show InChI InChI=1S/C9H9NO2SSe/c1-2-7-14-9-5-3-8(4-6-9)13(10,11)12/h1,3-6H,7H2,(H2,10,11,12) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50337754
((Z)-5-(((1R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hepta...)Show SMILES Cn1nc(sc1=NS(=O)(=O)C[C@@]12CCC(CC1=O)C2(C)C)S(N)(=O)=O |r,w:6.7| Show InChI InChI=1S/C13H20N4O5S3/c1-12(2)8-4-5-13(12,9(18)6-8)7-24(19,20)16-10-17(3)15-11(23-10)25(14,21)22/h8H,4-7H2,1-3H3,(H2,14,21,22)/t8?,13-/m0/s1 | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A mitochondrial isoform by stopped-flow CO2 hydration assay |
Bioorg Med Chem Lett 21: 1334-7 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.050
BindingDB Entry DOI: 10.7270/Q2930TF6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35733
(sulfonamide deriv., 7a)Show InChI InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-12(7-9-13)16-14(17)10-11-4-2-1-3-5-11/h1-9H,10H2,(H,16,17)(H2,15,18,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 6.70 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35739
(sulfonamide deriv., 7g)Show InChI InChI=1S/C13H13N3O3S/c14-20(18,19)12-6-4-10(5-7-12)16-13(17)9-11-3-1-2-8-15-11/h1-8H,9H2,(H,16,17)(H2,14,18,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.80 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341389
(CHEMBL4164747)Show SMILES [#7]S(=O)(=O)c1ccc([Se;v2][#6]-[#6]=[#6])cc1 Show InChI InChI=1S/C9H11NO2SSe/c1-2-7-14-9-5-3-8(4-6-9)13(10,11)12/h2-6H,1,7H2,(H2,10,11,12) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35727
(sulfonamide deriv., 5b)Show InChI InChI=1S/C12H11FN2O3S2/c13-10-7-9(20(14,17)18)3-4-11(10)15-12(16)6-8-2-1-5-19-8/h1-5,7H,6H2,(H,15,16)(H2,14,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 6.90 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341393
(CHEMBL4165154)Show SMILES [#6]-[#6](-[#6])[Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO2SSe/c1-7(2)14-9-5-3-8(4-6-9)13(10,11)12/h3-7H,1-2H3,(H2,10,11,12) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341387
(CHEMBL4161324)Show InChI InChI=1S/C10H11NO2SSe/c1-2-3-8-15-10-6-4-9(5-7-10)14(11,12)13/h4-7H,8H2,1H3,(H2,11,12,13) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35738
(sulfonamide deriv., 7f)Show InChI InChI=1S/C14H13BrN2O3S/c15-12-9-11(21(16,19)20)6-7-13(12)17-14(18)8-10-4-2-1-3-5-10/h1-7,9H,8H2,(H,17,18)(H2,16,19,20) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.10 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35726
(sulfonamide deriv., 5a)Show InChI InChI=1S/C12H12N2O3S2/c13-19(16,17)11-5-3-9(4-6-11)14-12(15)8-10-2-1-7-18-10/h1-7H,8H2,(H,14,15)(H2,13,16,17) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| 7.20 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341386
(CHEMBL4173057)Show InChI InChI=1S/C7H9NO2SSe/c1-12-7-4-2-6(3-5-7)11(8,9)10/h2-5H,1H3,(H2,8,9,10) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50279705
(CHEMBL4161289)Show SMILES [#7]S(=O)(=O)c1ccc([Se;v2][Se;v2]c2ccc(cc2)S([#7])(=O)=O)cc1 Show InChI InChI=1S/C12H12N2O4S2Se2/c13-19(15,16)9-1-5-11(6-2-9)21-22-12-7-3-10(4-8-12)20(14,17)18/h1-8H,(H2,13,15,16)(H2,14,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35740
(sulfonamide deriv., 7h)Show InChI InChI=1S/C13H13N3O3S/c14-20(18,19)12-3-1-11(2-4-12)16-13(17)9-10-5-7-15-8-6-10/h1-8H,9H2,(H,16,17)(H2,14,18,19) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.30 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35729
(sulfonamide deriv., 5d)Show InChI InChI=1S/C12H11BrN2O3S2/c13-10-7-9(20(14,17)18)3-4-11(10)15-12(16)6-8-2-1-5-19-8/h1-5,7H,6H2,(H,15,16)(H2,14,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.5 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35741
(sulfonamide deriv., 7i)Show InChI InChI=1S/C15H17N3O3S/c16-22(20,21)14-3-1-12(2-4-14)7-10-18-15(19)11-13-5-8-17-9-6-13/h1-6,8-9H,7,10-11H2,(H,18,19)(H2,16,20,21) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.60 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35732
(sulfonamide deriv., 6)Show InChI InChI=1S/C8H8N4O3S3/c9-18(14,15)8-12-11-7(17-8)10-6(13)4-5-2-1-3-16-5/h1-3H,4H2,(H2,9,14,15)(H,10,11,13) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| MMDB
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| 7.60 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35728
(sulfonamide deriv., 5c)Show InChI InChI=1S/C12H11ClN2O3S2/c13-10-7-9(20(14,17)18)3-4-11(10)15-12(16)6-8-2-1-5-19-8/h1-5,7H,6H2,(H,15,16)(H2,14,17,18) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.70 | -11.1 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35735
(sulfonamide deriv., 7c)Show InChI InChI=1S/C16H18N2O3S/c17-22(20,21)15-8-6-13(7-9-15)10-11-18-16(19)12-14-4-2-1-3-5-14/h1-9H,10-12H2,(H,18,19)(H2,17,20,21) | Reactome pathway
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| 8.10 | -11.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50279713
(CHEMBL4159870)Show InChI InChI=1S/C7H6N2O2SSe/c8-5-13-7-3-1-6(2-4-7)12(9,10)11/h1-4H,(H2,9,10,11) | Reactome pathway
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| 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35737
(sulfonamide deriv., 7e)Show InChI InChI=1S/C14H13ClN2O3S/c15-12-9-11(21(16,19)20)6-7-13(12)17-14(18)8-10-4-2-1-3-5-10/h1-7,9H,8H2,(H,17,18)(H2,16,19,20) | Reactome pathway
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| 8.20 | -11.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35736
(sulfonamide deriv., 7d)Show InChI InChI=1S/C14H13FN2O3S/c15-12-9-11(21(16,19)20)6-7-13(12)17-14(18)8-10-4-2-1-3-5-10/h1-7,9H,8H2,(H,17,18)(H2,16,19,20) | Reactome pathway
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| 8.30 | -11.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35742
(sulfonamide deriv., 8)Show InChI InChI=1S/C10H10N4O3S2/c11-19(16,17)10-14-13-9(18-10)12-8(15)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,11,16,17)(H,12,13,15) | Reactome pathway
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| 8.40 | -11.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35734
(sulfonamide deriv., 7b)Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20) | Reactome pathway
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| 8.60 | -11.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35734
(sulfonamide deriv., 7b)Show InChI InChI=1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20) | Reactome pathway
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| 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Inhibition of human CA5A by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 21: 6674-80 (2013)
Article DOI: 10.1016/j.bmc.2013.08.011
BindingDB Entry DOI: 10.7270/Q2V40Z44 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50341392
(CHEMBL4171524)Show SMILES [#7]S(=O)(=O)c1ccc([Se;v2][#6]-2-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C12H17NO2SSe/c13-16(14,15)10-6-8-12(9-7-10)17-11-4-2-1-3-5-11/h6-9,11H,1-5H2,(H2,13,14,15) | Reactome pathway
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| 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076
BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35730
(cid_694792 | sulfonamide deriv., 5e)Show InChI InChI=1S/C13H14N2O3S2/c14-20(17,18)12-5-3-10(4-6-12)9-15-13(16)8-11-2-1-7-19-11/h1-7H,8-9H2,(H,15,16)(H2,14,17,18) | Reactome pathway
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| 9.10 | -11.0 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50262015
(4-(4-o-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)Show InChI InChI=1S/C15H14N4O2S/c1-11-4-2-3-5-14(11)15-10-19(18-17-15)12-6-8-13(9-7-12)22(16,20)21/h2-10H,1H3,(H2,16,20,21) | Reactome pathway
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| 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50469143
(CHEMBL4293677)Show SMILES [#7]S(=O)(=O)c1ccc(cc1)-c1ncc([se;v2]1)-c1ccccc1 Show InChI InChI=1S/C15H12N2O2SSe/c16-20(18,19)13-8-6-12(7-9-13)15-17-10-14(21-15)11-4-2-1-3-5-11/h1-10H,(H2,16,18,19) | Reactome pathway
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| 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of University of Florence
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human carbonic anhydrase 5a incubated for 15 mins prior to testing by stopped flow CO2 hydration assay |
Eur J Med Chem 157: 1214-1222 (2018)
Article DOI: 10.1016/j.ejmech.2018.08.096
BindingDB Entry DOI: 10.7270/Q2RR21ZR |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35731
(sulfonamide deriv., 5f)Show InChI InChI=1S/C14H16N2O3S2/c15-21(18,19)13-5-3-11(4-6-13)7-8-16-14(17)10-12-2-1-9-20-12/h1-6,9H,7-8,10H2,(H,16,17)(H2,15,18,19) | Reactome pathway
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| 10.2 | -10.9 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
Istanbul University
| Assay Description
An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol... |
Bioorg Med Chem 17: 4894-9 (2009)
Article DOI: 10.1016/j.bmc.2009.06.006
BindingDB Entry DOI: 10.7270/Q2RJ4GT1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50262065
(4-(4-(4-methoxyphenyl)-1H-1,2,3-triazol-1-yl)benze...)Show SMILES COc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H14N4O3S/c1-22-13-6-2-11(3-7-13)15-10-19(18-17-15)12-4-8-14(9-5-12)23(16,20)21/h2-10H,1H3,(H2,16,20,21) | Reactome pathway
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| 10.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50262063
(4-(4-p-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)Show InChI InChI=1S/C15H14N4O2S/c1-11-2-4-12(5-3-11)15-10-19(18-17-15)13-6-8-14(9-7-13)22(16,20)21/h2-10H,1H3,(H2,16,20,21) | Reactome pathway
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| 12.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM35733
(sulfonamide deriv., 7a)Show InChI InChI=1S/C14H14N2O3S/c15-20(18,19)13-8-6-12(7-9-13)16-14(17)10-11-4-2-1-3-5-11/h1-9H,10H2,(H,16,17)(H2,15,18,19) | Reactome pathway
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| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Inhibition of human CA5A by stopped-flow CO2 hydrase assay |
Bioorg Med Chem 21: 6674-80 (2013)
Article DOI: 10.1016/j.bmc.2013.08.011
BindingDB Entry DOI: 10.7270/Q2V40Z44 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50262067
(4-(4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl)benzen...)Show InChI InChI=1S/C14H11FN4O2S/c15-11-3-1-10(2-4-11)14-9-19(18-17-14)12-5-7-13(8-6-12)22(16,20)21/h1-9H,(H2,16,20,21) | Reactome pathway
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| 14.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50262066
(4-{1-[4-(aminosulfonyl)phenyl]-1H-1,2,3-triazol-4-...)Show SMILES NS(=O)(=O)c1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C14H13N5O4S2/c15-24(20,21)12-5-1-10(2-6-12)14-9-19(18-17-14)11-3-7-13(8-4-11)25(16,22)23/h1-9H,(H2,15,20,21)(H2,16,22,23) | Reactome pathway
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| 15.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50337748
(4-((((1R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1...)Show SMILES CC1(C)C2CC[C@]1(CS(=O)(=O)NCc1ccc(cc1)S(N)(=O)=O)C(=O)C2 |r| Show InChI InChI=1S/C17H24N2O5S2/c1-16(2)13-7-8-17(16,15(20)9-13)11-25(21,22)19-10-12-3-5-14(6-4-12)26(18,23)24/h3-6,13,19H,7-11H2,1-2H3,(H2,18,23,24)/t13?,17-/m0/s1 | Reactome pathway
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| 16.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A mitochondrial isoform by stopped-flow CO2 hydration assay |
Bioorg Med Chem Lett 21: 1334-7 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.050
BindingDB Entry DOI: 10.7270/Q2930TF6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50261759
(4-(4-(4-methoxy-2-methylphenyl)-1H-1,2,3-triazol-1...)Show SMILES COc1ccc(-c2cn(nn2)-c2ccc(cc2)S(N)(=O)=O)c(C)c1 Show InChI InChI=1S/C16H16N4O3S/c1-11-9-13(23-2)5-8-15(11)16-10-20(19-18-16)12-3-6-14(7-4-12)24(17,21)22/h3-10H,1-2H3,(H2,17,21,22) | Reactome pathway
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| 16.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50261760
(4-(4-(2-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-...)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(nn1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C15H11F3N4O2S/c16-15(17,18)13-4-2-1-3-12(13)14-9-22(21-20-14)10-5-7-11(8-6-10)25(19,23)24/h1-9H,(H2,19,23,24) | Reactome pathway
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| 17.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50337746
(4-(((1R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-...)Show SMILES CC1(C)C2CC[C@]1(CS(=O)(=O)Nc1ccc(cc1)S(N)(=O)=O)C(=O)C2 |r| Show InChI InChI=1S/C16H22N2O5S2/c1-15(2)11-7-8-16(15,14(19)9-11)10-24(20,21)18-12-3-5-13(6-4-12)25(17,22)23/h3-6,11,18H,7-10H2,1-2H3,(H2,17,22,23)/t11?,16-/m0/s1 | Reactome pathway
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| 17.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A mitochondrial isoform by stopped-flow CO2 hydration assay |
Bioorg Med Chem Lett 21: 1334-7 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.050
BindingDB Entry DOI: 10.7270/Q2930TF6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50262062
(4-(4-phenyl-1H-1,2,3-triazol-1-yl)benzenesulfonami...)Show InChI InChI=1S/C14H12N4O2S/c15-21(19,20)13-8-6-12(7-9-13)18-10-14(16-17-18)11-4-2-1-3-5-11/h1-10H,(H2,15,19,20) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 17.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50261758
(4-(4-(4-fluoro-3-methylphenyl)-1H-1,2,3-triazol-1-...)Show SMILES Cc1cc(ccc1F)-c1cn(nn1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C15H13FN4O2S/c1-10-8-11(2-7-14(10)16)15-9-20(19-18-15)12-3-5-13(6-4-12)23(17,21)22/h2-9H,1H3,(H2,17,21,22) | Reactome pathway
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| CHEMBL
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UniChem
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PubMed
| 19.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50262064
(4-(4-m-tolyl-1H-1,2,3-triazol-1-yl)benzenesulfonam...)Show InChI InChI=1S/C15H14N4O2S/c1-11-3-2-4-12(9-11)15-10-19(18-17-15)13-5-7-14(8-6-13)22(16,20)21/h2-10H,1H3,(H2,16,20,21) | Reactome pathway
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| CHEMBL
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UniChem
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| Article
PubMed
| 19.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | Reactome pathway
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CHEMBL
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| DrugBank
Article
PubMed
| 20 | -10.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR
| Assay Description
Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly... |
Chem Biol Drug Des 74: 317-21 (2009)
Article DOI: 10.1111/j.1747-0285.2009.00857.x
BindingDB Entry DOI: 10.7270/Q2833QHP |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | Reactome pathway
KEGG
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CHEMBL
DrugBank
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PC sid
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| DrugBank
Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A mitochondrial isoform by stopped-flow CO2 hydration assay |
Bioorg Med Chem Lett 21: 1334-7 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.050
BindingDB Entry DOI: 10.7270/Q2930TF6 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | Reactome pathway
KEGG
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CHEMBL
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| DrugBank
Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 18: 4624-7 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.010
BindingDB Entry DOI: 10.7270/Q2959JF0 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM10888
(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)Show InChI InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) | Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CA5A by stopped flow CO2 hydrase assay |
J Med Chem 53: 850-4 (2010)
Article DOI: 10.1021/jm901524f
BindingDB Entry DOI: 10.7270/Q2PV6M96 |
More data for this
Ligand-Target Pair | |
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