Found 60 hits of ic50 for UniProtKB: P38936 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50609127
(CHEMBL5277005) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| UniChem
| | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410001
(CHEMBL368233)Show SMILES O=C(Nc1cccc(c1)-c1ccnc2c(cnn12)C(=O)c1cccs1)C1CC1 Show InChI InChI=1S/C21H16N4O2S/c26-19(18-5-2-10-28-18)16-12-23-25-17(8-9-22-20(16)25)14-3-1-4-15(11-14)24-21(27)13-6-7-13/h1-5,8-13H,6-7H2,(H,24,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50609126
(CHEMBL5266126) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50459994
(CHEMBL4226806 | US11471446, Compound DBA-8)Show InChI InChI=1S/C17H14N4/c18-11-14-6-7-16-15(10-14)17(21-12-20-16)19-9-8-13-4-2-1-3-5-13/h1-7,10,12H,8-9H2,(H,19,20,21) | PDB
Reactome pathway
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MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description
Inhibition of p21 (unknown origin)-induced transcription in human HT1080 p21-9-CMV-GFP cells after 3 days by fluorescence assay |
J Med Chem 61: 5073-5092 (2018)
Article DOI: 10.1021/acs.jmedchem.7b00901
BindingDB Entry DOI: 10.7270/Q29W0J3B |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410017
(CHEMBL179694)Show InChI InChI=1S/C17H15FN2O2S/c1-22-9-6-7-10(12(18)8-9)15-19-16(21)14-11-4-2-3-5-13(11)23-17(14)20-15/h6-8H,2-5H2,1H3,(H,19,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410009
(CHEMBL178807)Show SMILES COc1cc(cc(OC)c1OC)-c1nc2sc3CCCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C20H22N2O4S/c1-24-13-9-11(10-14(25-2)17(13)26-3)18-21-19(23)16-12-7-5-4-6-8-15(12)27-20(16)22-18/h9-10H,4-8H2,1-3H3,(H,21,22,23) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50609125
(CHEMBL1434157) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410003
(CHEMBL179730)Show SMILES COc1cc(cc(OC)c1OC)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C19H20N2O4S/c1-23-12-8-10(9-13(24-2)16(12)25-3)17-20-18(22)15-11-6-4-5-7-14(11)26-19(15)21-17/h8-9H,4-7H2,1-3H3,(H,20,21,22) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410005
(CHEMBL179110)Show InChI InChI=1S/C16H14N2O2S/c1-20-10-7-5-9(6-8-10)14-17-15(19)13-11-3-2-4-12(11)21-16(13)18-14/h5-8H,2-4H2,1H3,(H,17,18,19) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410012
(CHEMBL178310)Show InChI InChI=1S/C17H16N2O2S/c1-21-11-8-6-10(7-9-11)15-18-16(20)14-12-4-2-3-5-13(12)22-17(14)19-15/h6-9H,2-5H2,1H3,(H,18,19,20) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410006
(CHEMBL425866)Show SMILES COc1cc(cc(OC)c1OC)-c1nc2sc3CCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C18H18N2O4S/c1-22-11-7-9(8-12(23-2)15(11)24-3)16-19-17(21)14-10-5-4-6-13(10)25-18(14)20-16/h7-8H,4-6H2,1-3H3,(H,19,20,21) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410010
(CHEMBL179916)Show InChI InChI=1S/C17H16N2OS2/c1-21-11-8-6-10(7-9-11)15-18-16(20)14-12-4-2-3-5-13(12)22-17(14)19-15/h6-9H,2-5H2,1H3,(H,18,19,20) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410009
(CHEMBL178807)Show SMILES COc1cc(cc(OC)c1OC)-c1nc2sc3CCCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C20H22N2O4S/c1-24-13-9-11(10-14(25-2)17(13)26-3)18-21-19(23)16-12-7-5-4-6-8-15(12)27-20(16)22-18/h9-10H,4-8H2,1-3H3,(H,21,22,23) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410016
(CHEMBL179178)Show InChI InChI=1S/C18H18N2O2S/c1-2-22-12-9-7-11(8-10-12)16-19-17(21)15-13-5-3-4-6-14(13)23-18(15)20-16/h7-10H,2-6H2,1H3,(H,19,20,21) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410001
(CHEMBL368233)Show SMILES O=C(Nc1cccc(c1)-c1ccnc2c(cnn12)C(=O)c1cccs1)C1CC1 Show InChI InChI=1S/C21H16N4O2S/c26-19(18-5-2-10-28-18)16-12-23-25-17(8-9-22-20(16)25)14-3-1-4-15(11-14)24-21(27)13-6-7-13/h1-5,8-13H,6-7H2,(H,24,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 deficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410017
(CHEMBL179694)Show InChI InChI=1S/C17H15FN2O2S/c1-22-9-6-7-10(12(18)8-9)15-19-16(21)14-11-4-2-3-5-13(11)23-17(14)20-15/h6-8H,2-5H2,1H3,(H,19,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410015
(CHEMBL179113)Show InChI InChI=1S/C20H22N2O2S/c1-2-3-12-24-14-10-8-13(9-11-14)18-21-19(23)17-15-6-4-5-7-16(15)25-20(17)22-18/h8-11H,2-7,12H2,1H3,(H,21,22,23) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410014
(CHEMBL178995)Show SMILES COc1cc(cc(OC)c1OC)-c1cc(Nc2ccccc2)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C26H26N2O3S/c1-29-21-13-16(14-22(30-2)25(21)31-3)19-15-20(27-17-9-5-4-6-10-17)24-18-11-7-8-12-23(18)32-26(24)28-19/h4-6,9-10,13-15H,7-8,11-12H2,1-3H3,(H,27,28) | PDB
Reactome pathway
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410018
(CHEMBL179187)Show InChI InChI=1S/C20H20ClNO3S/c1-23-15-8-11(9-16(24-2)19(15)25-3)14-10-13(21)18-12-6-4-5-7-17(12)26-20(18)22-14/h8-10H,4-7H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410019
(CHEMBL180572)Show InChI InChI=1S/C15H14N2O4S/c1-19-10-6-8(7-11(20-2)12(10)21-3)14-16-9-4-5-22-13(9)15(18)17-14/h4-7H,1-3H3,(H,16,17,18) | PDB
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CHEMBL
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PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410020
(CHEMBL538355)Show SMILES COc1cc(cc(OC)c1OC)-c1cc(-c2cccs2)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C24H23NO3S2/c1-26-18-11-14(12-19(27-2)23(18)28-3)17-13-16(20-9-6-10-29-20)22-15-7-4-5-8-21(15)30-24(22)25-17/h6,9-13H,4-5,7-8H2,1-3H3 | PDB
Reactome pathway
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410021
(CHEMBL179692)Show InChI InChI=1S/C17H16N2OS/c1-10-6-8-11(9-7-10)15-18-16(20)14-12-4-2-3-5-13(12)21-17(14)19-15/h6-9H,2-5H2,1H3,(H,18,19,20) | PDB
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CHEMBL
PC cid
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| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410021
(CHEMBL179692)Show InChI InChI=1S/C17H16N2OS/c1-10-6-8-11(9-7-10)15-18-16(20)14-12-4-2-3-5-13(12)21-17(14)19-15/h6-9H,2-5H2,1H3,(H,18,19,20) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410004
(CHEMBL179920)Show SMILES O=c1[nH]c(nc2sc3CCCCc3c12)-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C22H18N2O2S/c25-21-19-17-8-4-5-9-18(17)27-22(19)24-20(23-21)14-10-12-16(13-11-14)26-15-6-2-1-3-7-15/h1-3,6-7,10-13H,4-5,8-9H2,(H,23,24,25) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410018
(CHEMBL179187)Show InChI InChI=1S/C20H20ClNO3S/c1-23-15-8-11(9-16(24-2)19(15)25-3)14-10-13(21)18-12-6-4-5-7-17(12)26-20(18)22-14/h8-10H,4-7H2,1-3H3 | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410011
(CHEMBL179087)Show SMILES COc1cc(cc(OC)c1OC)-c1cc(N(C)C)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C22H26N2O3S/c1-24(2)16-12-15(13-10-17(25-3)21(27-5)18(11-13)26-4)23-22-20(16)14-8-6-7-9-19(14)28-22/h10-12H,6-9H2,1-5H3 | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410020
(CHEMBL538355)Show SMILES COc1cc(cc(OC)c1OC)-c1cc(-c2cccs2)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C24H23NO3S2/c1-26-18-11-14(12-19(27-2)23(18)28-3)17-13-16(20-9-6-10-29-20)22-15-7-4-5-8-21(15)30-24(22)25-17/h6,9-13H,4-5,7-8H2,1-3H3 | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410002
(CHEMBL360323)Show InChI InChI=1S/C15H14N2O4S/c1-19-10-6-8(7-11(20-2)12(10)21-3)13-16-14(18)9-4-5-22-15(9)17-13/h4-7H,1-3H3,(H,16,17,18) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410019
(CHEMBL180572)Show InChI InChI=1S/C15H14N2O4S/c1-19-10-6-8(7-11(20-2)12(10)21-3)14-16-9-4-5-22-13(9)15(18)17-14/h4-7H,1-3H3,(H,16,17,18) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410010
(CHEMBL179916)Show InChI InChI=1S/C17H16N2OS2/c1-21-11-8-6-10(7-9-11)15-18-16(20)14-12-4-2-3-5-13(12)22-17(14)19-15/h6-9H,2-5H2,1H3,(H,18,19,20) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410022
(CHEMBL179581)Show InChI InChI=1S/C18H18N2O3S/c1-22-12-8-7-10(9-13(12)23-2)16-19-17(21)15-11-5-3-4-6-14(11)24-18(15)20-16/h7-9H,3-6H2,1-2H3,(H,19,20,21) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410023
(CHEMBL359939)Show SMILES CC(C)Oc1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C19H20N2O2S/c1-11(2)23-13-9-7-12(8-10-13)17-20-18(22)16-14-5-3-4-6-15(14)24-19(16)21-17/h7-11H,3-6H2,1-2H3,(H,20,21,22) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410013
(CHEMBL179155)Show InChI InChI=1S/C21H23NO4S/c1-23-15-11-14(12-9-16(24-2)20(26-4)17(10-12)25-3)22-21-19(15)13-7-5-6-8-18(13)27-21/h9-11H,5-8H2,1-4H3 | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410024
(CHEMBL361956)Show SMILES COc1cc(OC)cc(c1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C18H18N2O3S/c1-22-11-7-10(8-12(9-11)23-2)16-19-17(21)15-13-5-3-4-6-14(13)24-18(15)20-16/h7-9H,3-6H2,1-2H3,(H,19,20,21) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410007
(CHEMBL359861)Show InChI InChI=1S/C13H10N2O2S/c1-17-9-4-2-8(3-5-9)12-14-10-6-7-18-11(10)13(16)15-12/h2-7H,1H3,(H,14,15,16) | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410023
(CHEMBL359939)Show SMILES CC(C)Oc1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C19H20N2O2S/c1-11(2)23-13-9-7-12(8-10-13)17-20-18(22)16-14-5-3-4-6-15(14)24-19(16)21-17/h7-11H,3-6H2,1-2H3,(H,20,21,22) | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410016
(CHEMBL179178)Show InChI InChI=1S/C18H18N2O2S/c1-2-22-12-9-7-11(8-10-12)16-19-17(21)15-13-5-3-4-6-14(13)23-18(15)20-16/h7-10H,2-6H2,1H3,(H,19,20,21) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410024
(CHEMBL361956)Show SMILES COc1cc(OC)cc(c1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C18H18N2O3S/c1-22-11-7-10(8-12(9-11)23-2)16-19-17(21)15-13-5-3-4-6-14(13)24-18(15)20-16/h7-9H,3-6H2,1-2H3,(H,19,20,21) | PDB
Reactome pathway
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410022
(CHEMBL179581)Show InChI InChI=1S/C18H18N2O3S/c1-22-12-8-7-10(9-13(12)23-2)16-19-17(21)15-11-5-3-4-6-14(11)24-18(15)20-16/h7-9H,3-6H2,1-2H3,(H,19,20,21) | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410025
(CHEMBL360687)Show InChI InChI=1S/C16H13ClN2OS/c17-10-7-5-9(6-8-10)14-18-15(20)13-11-3-1-2-4-12(11)21-16(13)19-14/h5-8H,1-4H2,(H,18,19,20) | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410026
(CHEMBL178907)Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C16H13N3O3S/c20-15-13-11-3-1-2-4-12(11)23-16(13)18-14(17-15)9-5-7-10(8-6-9)19(21)22/h5-8H,1-4H2,(H,17,18,20) | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410025
(CHEMBL360687)Show InChI InChI=1S/C16H13ClN2OS/c17-10-7-5-9(6-8-10)14-18-15(20)13-11-3-1-2-4-12(11)21-16(13)19-14/h5-8H,1-4H2,(H,18,19,20) | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410026
(CHEMBL178907)Show SMILES [O-][N+](=O)c1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C16H13N3O3S/c20-15-13-11-3-1-2-4-12(11)23-16(13)18-14(17-15)9-5-7-10(8-6-9)19(21)22/h5-8H,1-4H2,(H,17,18,20) | PDB
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| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410015
(CHEMBL179113)Show InChI InChI=1S/C20H22N2O2S/c1-2-3-12-24-14-10-8-13(9-11-14)18-21-19(23)17-15-6-4-5-7-16(15)25-20(17)22-18/h8-11H,2-7,12H2,1H3,(H,21,22,23) | PDB
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Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410014
(CHEMBL178995)Show SMILES COc1cc(cc(OC)c1OC)-c1cc(Nc2ccccc2)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C26H26N2O3S/c1-29-21-13-16(14-22(30-2)25(21)31-3)19-15-20(27-17-9-5-4-6-10-17)24-18-11-7-8-12-23(18)32-26(24)28-19/h4-6,9-10,13-15H,7-8,11-12H2,1-3H3,(H,27,28) | PDB
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410008
(CHEMBL368648)Show SMILES COC(=O)c1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C18H16N2O3S/c1-23-18(22)11-8-6-10(7-9-11)15-19-16(21)14-12-4-2-3-5-13(12)24-17(14)20-15/h6-9H,2-5H2,1H3,(H,19,20,21) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410013
(CHEMBL179155)Show InChI InChI=1S/C21H23NO4S/c1-23-15-11-14(12-9-16(24-2)20(26-4)17(10-12)25-3)22-21-19(15)13-7-5-6-8-18(13)27-21/h9-11H,5-8H2,1-4H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410012
(CHEMBL178310)Show InChI InChI=1S/C17H16N2O2S/c1-21-11-8-6-10(7-9-11)15-18-16(20)14-12-4-2-3-5-13(12)22-17(14)19-15/h6-9H,2-5H2,1H3,(H,18,19,20) | PDB
Reactome pathway
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against human p21 proficient cell (p21+/+) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410011
(CHEMBL179087)Show SMILES COc1cc(cc(OC)c1OC)-c1cc(N(C)C)c2c3CCCCc3sc2n1 Show InChI InChI=1S/C22H26N2O3S/c1-24(2)16-12-15(13-10-17(25-3)21(27-5)18(11-13)26-4)23-22-20(16)14-8-6-7-9-19(14)28-22/h10-12H,6-9H2,1-5H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase inhibitor 1
(Homo sapiens (Human)) | BDBM50410008
(CHEMBL368648)Show SMILES COC(=O)c1ccc(cc1)-c1nc2sc3CCCCc3c2c(=O)[nH]1 Show InChI InChI=1S/C18H16N2O3S/c1-23-18(22)11-8-6-10(7-9-11)15-19-16(21)14-12-4-2-3-5-13(12)24-17(14)20-15/h6-9H,2-5H2,1H3,(H,19,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibitory concentration against p21 deficient cell (p21-/-) proliferation |
Bioorg Med Chem Lett 15: 3763-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.127
BindingDB Entry DOI: 10.7270/Q2XG9SB7 |
More data for this
Ligand-Target Pair | |
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