Compile Data Set for Download or QSAR

Found 33 hits of ic50 for UniProtKB: P35327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265812 ((S)-3-(3-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...) Show SMILES Ic1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C13H14INO3/c14-10-3-1-2-9(8-10)4-5-12(16)15-11-6-7-18-13(11)17/h1-3,8,11H,4-7H2,(H,15,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265861 ((S)-N-(2-oxotetrahydrofuran-3-yl)-3-(3-(trifluorom...) Show SMILES FC(F)(F)c1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C14H14F3NO3/c15-14(16,17)10-3-1-2-9(8-10)4-5-12(19)18-11-6-7-21-13(11)20/h1-3,8,11H,4-7H2,(H,18,19)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265810 ((S)-3-(3-bromophenyl)-N-(2-oxotetrahydrofuran-3-yl...) Show SMILES Brc1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C13H14BrNO3/c14-10-3-1-2-9(8-10)4-5-12(16)15-11-6-7-18-13(11)17/h1-3,8,11H,4-7H2,(H,15,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266163 ((S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...) Show SMILES Ic1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C12H12INO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50608092 (CHEMBL473573) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50373105 (CHEMBL259441) Show SMILES O=C(Cc1ccc(cc1)-c1ccccc1)N[C@H]1CCOC1=O Show InChI InChI=1S/C18H17NO3/c20-17(19-16-10-11-22-18(16)21)12-13-6-8-15(9-7-13)14-4-2-1-3-5-14/h1-9,16H,10-12H2,(H,19,20)/t16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266165 ((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...) Show SMILES FC(F)(F)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50527012 (CHEMBL4571277) Show SMILES Clc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C12H12ClNO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266165 ((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...) Show SMILES FC(F)(F)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265811 ((S)-3-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...) Show SMILES Ic1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H14INO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266163 ((S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)...) Show SMILES Ic1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C12H12INO3/c13-9-3-1-8(2-4-9)7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265901 ((S)-3-(3-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...) Show SMILES [O-][N+](=O)c1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C13H14N2O5/c16-12(14-11-6-7-20-13(11)17)5-4-9-2-1-3-10(8-9)15(18)19/h1-3,8,11H,4-7H2,(H,14,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266238 ((S)-2-(naphthalen-2-yl)-N-(2-oxotetrahydrofuran-3-...) Show SMILES O=C(Cc1ccc2ccccc2c1)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H15NO3/c18-15(17-14-7-8-20-16(14)19)10-11-5-6-12-3-1-2-4-13(12)9-11/h1-6,9,14H,7-8,10H2,(H,17,18)/t14-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266164 ((S)-2-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...) Show SMILES [O-][N+](=O)c1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C12H12N2O5/c15-11(13-10-5-6-19-12(10)16)7-8-1-3-9(4-2-8)14(17)18/h1-4,10H,5-7H2,(H,13,15)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265809 ((S)-3-(4-chlorophenyl)-N-(2-oxotetrahydrofuran-3-y...) Show SMILES Clc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H14ClNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265900 ((S)-3-(4-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl...) Show SMILES [O-][N+](=O)c1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H14N2O5/c16-12(14-11-7-8-20-13(11)17)6-3-9-1-4-10(5-2-9)15(18)19/h1-2,4-5,11H,3,6-8H2,(H,14,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266236 ((S)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(2-ox...) Show SMILES Fc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1C(F)(F)F |r| Show InChI InChI=1S/C13H11F4NO3/c14-9-2-1-7(5-8(9)13(15,16)17)6-11(19)18-10-3-4-21-12(10)20/h1-2,5,10H,3-4,6H2,(H,18,19)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266234 ((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(4-(trifluorom...) Show SMILES FC(F)(F)Sc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H12F3NO3S/c14-13(15,16)21-9-3-1-8(2-4-9)7-11(18)17-10-5-6-20-12(10)19/h1-4,10H,5-7H2,(H,17,18)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266266 ((S)-2-(naphthalen-1-yl)-N-(2-oxotetrahydrofuran-3-...) Show SMILES O=C(Cc1cccc2ccccc12)N[C@H]1CCOC1=O |r| Show InChI InChI=1S/C16H15NO3/c18-15(17-14-8-9-20-16(14)19)10-12-6-3-5-11-4-1-2-7-13(11)12/h1-7,14H,8-10H2,(H,17,18)/t14-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50241433 ((S)-3-(4-bromophenyl)-N-(2-oxo-tetrahydrofuran-3-y...) Show SMILES Brc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H14BrNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266201 ((S)-N-(2-oxotetrahydrofuran-3-yl)-2-(3-(trifluorom...) Show SMILES FC(F)(F)c1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C13H12F3NO3/c14-13(15,16)9-3-1-2-8(6-9)7-11(18)17-10-4-5-20-12(10)19/h1-3,6,10H,4-5,7H2,(H,17,18)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266233 ((S)-2-(3-(methylthio)phenyl)-N-(2-oxotetrahydrofur...) Show SMILES CSc1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C13H15NO3S/c1-18-10-4-2-3-9(7-10)8-12(15)14-11-5-6-17-13(11)16/h2-4,7,11H,5-6,8H2,1H3,(H,14,15)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265813 ((S)-3-(4-(methylthio)phenyl)-N-(2-oxotetrahydrofur...) Show SMILES CSc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C14H17NO3S/c1-19-11-5-2-10(3-6-11)4-7-13(16)15-12-8-9-18-14(12)17/h2-3,5-6,12H,4,7-9H2,1H3,(H,15,16)/t12-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266308 ((S)-2-(4-iodophenoxy)-N-(2-oxotetrahydrofuran-3-yl...) Show SMILES Ic1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C12H12INO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266199 ((S)-N-(2-oxotetrahydrofuran-3-yl)-2-m-tolylacetami...) Show SMILES Cc1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C13H15NO3/c1-9-3-2-4-10(7-9)8-12(15)14-11-5-6-17-13(11)16/h2-4,7,11H,5-6,8H2,1H3,(H,14,15)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266313 ((S)-N-(2-oxotetrahydrofuran-3-yl)-3-m-tolylpropana...) Show SMILES Cc1cccc(CCC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C14H17NO3/c1-10-3-2-4-11(9-10)5-6-13(16)15-12-7-8-18-14(12)17/h2-4,9,12H,5-8H2,1H3,(H,15,16)/t12-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266203 ((S)-2-(4-(methylthio)phenyl)-N-(2-oxotetrahydrofur...) Show SMILES CSc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H15NO3S/c1-18-10-4-2-9(3-5-10)8-12(15)14-11-6-7-17-13(11)16/h2-5,11H,6-8H2,1H3,(H,14,15)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265814 ((S)-N-(2-oxotetrahydrofuran-3-yl)-3-(4-(trifluorom...) Show SMILES FC(F)(F)c1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C14H14F3NO3/c15-14(16,17)10-4-1-9(2-5-10)3-6-12(19)18-11-7-8-21-13(11)20/h1-2,4-5,11H,3,6-8H2,(H,18,19)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266312 ((S)-N-(2-oxotetrahydrofuran-3-yl)-3-p-tolylpropana...) Show SMILES Cc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C14H17NO3/c1-10-2-4-11(5-3-10)6-7-13(16)15-12-8-9-18-14(12)17/h2-5,12H,6-9H2,1H3,(H,15,16)/t12-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266311 ((S)-2-(3-nitrophenoxy)-N-(2-oxotetrahydrofuran-3-y...) Show SMILES [O-][N+](=O)c1cccc(OCC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C12H12N2O6/c15-11(13-10-4-5-19-12(10)16)7-20-9-3-1-2-8(6-9)14(17)18/h1-3,6,10H,4-5,7H2,(H,13,15)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266200 ((S)-2-(3-methoxyphenyl)-N-(2-oxotetrahydrofuran-3-...) Show SMILES COc1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r| Show InChI InChI=1S/C13H15NO4/c1-17-10-4-2-3-9(7-10)8-12(15)14-11-5-6-18-13(11)16/h2-4,7,11H,5-6,8H2,1H3,(H,14,15)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50265808 ((S)-3-(4-fluorophenyl)-N-(2-oxotetrahydrofuran-3-y...) Show SMILES Fc1ccc(CCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C13H14FNO3/c14-10-4-1-9(2-5-10)3-6-12(16)15-11-7-8-18-13(11)17/h1-2,4-5,11H,3,6-8H2,(H,15,16)/t11-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair
Transcriptional activator protein LuxR (Vibrio fischeri (strain ATCC 700601 / ES114))	BDBM50266272 ((S)-2-(4-bromophenoxy)-N-(2-oxotetrahydrofuran-3-y...) Show SMILES Brc1ccc(OCC(=O)N[C@H]2CCOC2=O)cc1 |r| Show InChI InChI=1S/C12H12BrNO4/c13-8-1-3-9(4-2-8)18-7-11(15)14-10-5-6-17-12(10)16/h1-4,10H,5-7H2,(H,14,15)/t10-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Antagonist activity at Vibrio fischeri ES114 LuxR receptor assessed as inhibition of OHHL-induced response by luciferase reporter gene assay				Bioorg Med Chem Lett 18: 5978-81 (2008) Article DOI: 10.1016/j.bmcl.2008.07.089 BindingDB Entry DOI: 10.7270/Q2Q81CXX
					More data for this Ligand-Target Pair