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Compile Data Set for Download or QSAR

Found 43 hits of ec50 for UniProtKB: Q9UBY5   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430007
PNG
(CHEMBL2335051)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC(COC)COP(O)([O-])=S
Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)28-21(19-26-2)20-27-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/p-1
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n/an/an/an/a 0.210n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430006
PNG
(CHEMBL2335048)
Show SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC |r|
Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m1/s1
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n/an/an/an/a 0.230n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430012
PNG
(CHEMBL357053)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC
Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)27-19-21(26-2)20-28-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/t21-/m0/s1
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n/an/an/an/a 0.270n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50381022
PNG
(CHEMBL2017139)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(COP(O)(S)=O)OC
Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)27-19-21(26-2)20-28-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)
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n/an/an/an/a 0.280n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430009
PNG
(CHEMBL2335049)
Show SMILES CCCCCCCCCCCCCCCCOC(COC)COP(O)([O-])=S
Show InChI InChI=1S/C20H43O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24-20(18-23-2)19-25-26(21,22)27/h20H,3-19H2,1-2H3,(H2,21,22,27)/p-1
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n/an/an/an/a 0.360n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430010
PNG
(CHEMBL2335047)
Show SMILES CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC |r|
Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m0/s1
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n/an/an/an/a 0.370n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430008
PNG
(CHEMBL2335050)
Show SMILES CCCCCCCCCCCCCCCCCOC(COC)COP(O)([O-])=S
Show InChI InChI=1S/C21H45O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-25-21(19-24-2)20-26-27(22,23)28/h21H,3-20H2,1-2H3,(H2,22,23,28)/p-1
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n/an/an/an/a 0.390n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430011
PNG
(CHEMBL153043)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC
Show InChI InChI=1S/C22H45O6PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(23)27-19-21(26-2)20-28-29(24,25)30/h21H,3-20H2,1-2H3,(H2,24,25,30)/t21-/m1/s1
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n/an/an/an/a 0.440n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430006
PNG
(CHEMBL2335048)
Show SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP(O)(O)=S)OC |r|
Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m1/s1
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n/an/an/an/a 1.10n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50176390
PNG
((R)-O-2,3-bis(octyloxy)propyl O,O-dihydrogen phosp...)
Show SMILES CCCCCCCCOC[C@H](COP(O)(O)=S)OCCCCCCCC
Show InChI InChI=1S/C19H41O5PS/c1-3-5-7-9-11-13-15-22-17-19(18-24-25(20,21)26)23-16-14-12-10-8-6-4-2/h19H,3-18H2,1-2H3,(H2,20,21,26)/t19-/m1/s1
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n/an/an/an/a 3n/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50610650
PNG
(CHEMBL5285905)
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n/an/an/an/a<50n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50610652
PNG
(CHEMBL5281669)
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n/an/an/an/a<50n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50610651
PNG
(CHEMBL5277897)
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n/an/an/an/a<50n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148348
PNG
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O
Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1
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n/an/an/an/a 77n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50176399
PNG
(CHEMBL202242 | octanoic acid (S)-2-octanoyloxy-3-t...)
Show SMILES CCCCCCCC(=O)OC[C@@H](COP(O)(O)=S)OC(=O)CCCCCCC
Show InChI InChI=1S/C19H37O7PS/c1-3-5-7-9-11-13-18(20)24-15-17(16-25-27(22,23)28)26-19(21)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H2,22,23,28)/t17-/m0/s1
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n/an/an/an/a 115n/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148348
PNG
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O
Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1
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n/an/an/an/a 120n/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Agonist activity at LPA3 expressed in human chem1 cells assessed as intracellular calcium mobilization by FLIPR assay


Bioorg Med Chem 18: 477-95 (2010)


Article DOI: 10.1016/j.bmc.2009.12.020
BindingDB Entry DOI: 10.7270/Q2W66KWQ
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50176400
PNG
((R)-2,3-bis(octyloxy)propyl dihydrogen phosphate |...)
Show SMILES CCCCCCCCOC[C@H](COP(O)(O)=O)OCCCCCCCC
Show InChI InChI=1S/C19H41O6P/c1-3-5-7-9-11-13-15-23-17-19(18-25-26(20,21)22)24-16-14-12-10-8-6-4-2/h19H,3-18H2,1-2H3,(H2,20,21,22)/t19-/m1/s1
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n/an/an/an/a 164n/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148348
PNG
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O
Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1
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n/an/an/an/a 263n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50233165
PNG
(CHEMBL1222042)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OCC(O)COP(O)(O)=O
Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-
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n/an/an/an/a 290n/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Agonist activity at LPA3 receptor (unknown origin) expressed in rat RH7777 cells assessed as increase in intracellular calcium level measured every 3...


J Med Chem 60: 1309-1324 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01270
BindingDB Entry DOI: 10.7270/Q2K64MBD
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50170844
PNG
(CHEMBL187459 | Thiophosphoric acid (E)-octadec-9-e...)
Show SMILES CCCCCCCC\C=C\CCCCCCCCOP(O)(O)=S
Show InChI InChI=1S/C18H37O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-22(19,20)23/h9-10H,2-8,11-18H2,1H3,(H2,19,20,23)/b10-9+
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n/an/an/an/a 546n/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50430013
PNG
(CHEMBL364797)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O
Show InChI InChI=1S/C19H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18,20H,2-17H2,1H3,(H2,22,23,24)/t18-/m1/s1
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n/an/an/an/a 580n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay


Bioorg Med Chem Lett 23: 1865-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.002
BindingDB Entry DOI: 10.7270/Q2SN0B9G
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148348
PNG
((R)-Octadec-9-enoic acid 2-hydroxy-3-phosphonooxy-...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(O)=O
Show InChI InChI=1S/C21H41O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20,22H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9-/t20-/m1/s1
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n/an/an/an/a 830n/an/an/an/a



The University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Agonist activity at human LPA3 expressed in LPA1xLPA2 double knockout mouse MEF cells by Fura-2AM dye based Ca2+ mobilization assay


J Med Chem 57: 7136-40 (2014)


Article DOI: 10.1021/jm5007116
BindingDB Entry DOI: 10.7270/Q22V2HS4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50170848
PNG
(2-Hexadecanoylamino-3-phosphonooxy-propionic acid ...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(O)(O)=O)C(O)=O
Show InChI InChI=1S/C19H38NO7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)20-17(19(22)23)16-27-28(24,25)26/h17H,2-16H2,1H3,(H,20,21)(H,22,23)(H2,24,25,26)/t17-/m0/s1
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n/an/an/an/a 1.60E+3n/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Inhibition of LPA-induced calcium transients in RH7777 rat hepatoma cells expressing LPA3 receptor


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50074700
PNG
(CHEMBL117754 | Phosphoric acid mono-[2-((Z)-octade...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCOP(O)(O)=O
Show InChI InChI=1S/C20H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)21-18-19-26-27(23,24)25/h9-10H,2-8,11-19H2,1H3,(H,21,22)(H2,23,24,25)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148353
PNG
((1-Hydroxy-3-octadec-9-enoylamino-1-phosphono-prop...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C21H43NO8P2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21(24,31(25,26)27)32(28,29)30/h9-10,24H,2-8,11-19H2,1H3,(H,22,23)(H2,25,26,27)(H2,28,29,30)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148354
PNG
(CHEMBL117663 | [1-Fluoro-3-((Z)-octadec-9-enoylami...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(F)P(O)(O)=O
Show InChI InChI=1S/C21H41FNO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)23-19-18-20(22)28(25,26)27/h9-10,20H,2-8,11-19H2,1H3,(H,23,24)(H2,25,26,27)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148349
PNG
((3-Octadec-9-enoylamino-propionyl)-phosphonothioic...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(=O)P(O)(O)=S
Show InChI InChI=1S/C21H40NO4PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21(24)27(25,26)28/h9-10H,2-8,11-19H2,1H3,(H,22,23)(H2,25,26,28)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148350
PNG
(CHEMBL325970 | [3-((Z)-Octadec-9-enoylamino)-thiop...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(=S)P(O)(O)=O
Show InChI InChI=1S/C21H40NO4PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21(28)27(24,25)26/h9-10H,2-8,11-19H2,1H3,(H,22,23)(H2,24,25,26)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148352
PNG
(CHEMBL325288 | [1-Hydroxy-3-((Z)-octadec-9-enoylam...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(=O)P(O)(O)O
Show InChI InChI=1S/C21H42NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21(24)28(25,26)27/h9-10,25-28H,2-8,11-19H2,1H3,(H,22,23)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148351
PNG
(CHEMBL117529 | [3-((Z)-Octadec-9-enoylamino)-propi...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCC(=O)P(O)(O)=O
Show InChI InChI=1S/C21H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21(24)28(25,26)27/h9-10H,2-8,11-19H2,1H3,(H,22,23)(H2,25,26,27)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50148355
PNG
(CHEMBL331661 | [3-((Z)-Octadec-9-enoylamino)-propy...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCCP(O)(O)=O
Show InChI InChI=1S/C21H42NO4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(23)22-19-17-20-27(24,25)26/h9-10H,2-8,11-20H2,1H3,(H,22,23)(H2,24,25,26)/b10-9-
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n/an/an/an/a>5.00E+3n/an/an/an/a



Oxford University

Curated by ChEMBL


Assay Description
Agonistic activity against lysophosphatidic acid receptor 3 using [35S]-GTP-gammaS as radioligand tested in vitro


Bioorg Med Chem Lett 14: 3473-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.04.061
BindingDB Entry DOI: 10.7270/Q2D50MDW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50193516
PNG
(1,1-difluoro-3(S)-hydroxyl-4-oleoyloxylbutane 1,3-...)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)(F)P(O)(=O)O1
Show InChI InChI=1S/C22H41F2O5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(25)28-19-20-18-22(23,24)30(26,27)29-20/h20H,2-19H2,1H3,(H,26,27)/t20-/m0/s1
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n/an/an/an/a>7.03E+3n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assay


J Med Chem 49: 5309-15 (2006)


Article DOI: 10.1021/jm060351+
BindingDB Entry DOI: 10.7270/Q2VM4BWW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166111
PNG
((E)-Octadec-9-enoic acid (R)-2-fluoro-3-phosphonoo...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)OC[C@@H](F)COP(O)(O)=O
Show InChI InChI=1S/C21H40FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(23)27-18-20(22)19-28-29(24,25)26/h9-10,20H,2-8,11-19H2,1H3,(H2,24,25,26)/b10-9+/t20-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166113
PNG
(CHEMBL192210 | Hexadecanoic acid (R)-2-fluoro-3-ph...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@@H](F)COP(O)(O)=O
Show InChI InChI=1S/C19H38FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18H,2-17H2,1H3,(H2,22,23,24)/t18-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166112
PNG
((E)-Octadec-9-enoic acid (R)-2,2-difluoro-1-phosph...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)O[C@H](COP(O)(O)=O)C(F)F
Show InChI InChI=1S/C21H39F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(24)29-19(21(22)23)18-28-30(25,26)27/h9-10,19,21H,2-8,11-18H2,1H3,(H2,25,26,27)/b10-9+/t19-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166116
PNG
(CHEMBL191614 | Hexadecanoic acid (R)-4-fluoro-2-hy...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](O)CC(F)P(O)(O)=O
Show InChI InChI=1S/C20H40FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(23)27-17-18(22)16-19(21)28(24,25)26/h18-19,22H,2-17H2,1H3,(H2,24,25,26)/t18-,19?/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166117
PNG
(CHEMBL192452 | Hexadecanoic acid (S)-2-fluoro-3-ph...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](F)COP(O)(O)=O
Show InChI InChI=1S/C19H38FO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18H,2-17H2,1H3,(H2,22,23,24)/t18-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166114
PNG
((E)-Octadec-9-enoic acid (S)-3,3-difluoro-1-phosph...)
Show SMILES CCCCCCCC\C=C\CCCCCCCC(=O)O[C@H](COP(O)(O)=O)CC(F)F
Show InChI InChI=1S/C22H41F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(25)30-20(18-21(23)24)19-29-31(26,27)28/h9-10,20-21H,2-8,11-19H2,1H3,(H2,26,27,28)/b10-9+/t20-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166115
PNG
(CHEMBL190876 | PALMITOYL)
Show SMILES CCCCCCCCCCCCCCCC(=O)OCC(O)COP(O)([O-])=O
Show InChI InChI=1S/C19H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18,20H,2-17H2,1H3,(H2,22,23,24)/p-1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166120
PNG
(CHEMBL193196 | Hexadecanoic acid (S)-4-fluoro-2-me...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CC(F)P(O)(O)=O)OC
Show InChI InChI=1S/C21H42FO6P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21(23)28-18-19(27-2)17-20(22)29(24,25)26/h19-20H,3-18H2,1-2H3,(H2,24,25,26)/t19-,20?/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166119
PNG
(CHEMBL193406 | Hexadecanoic acid (S)-3,3-difluoro-...)
Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COP(O)(O)=O)CC(F)F
Show InChI InChI=1S/C20H39F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(23)28-18(16-19(21)22)17-27-29(24,25)26/h18-19H,2-17H2,1H3,(H2,24,25,26)/t18-/m0/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50166118
PNG
(CHEMBL195383 | Hexadecanoic acid (R)-2,2-difluoro-...)
Show SMILES CCCCCCCCCCCCCCCC(=O)O[C@H](COP(O)(O)=O)C(F)F
Show InChI InChI=1S/C19H37F2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(22)27-17(19(20)21)16-26-28(23,24)25/h17,19H,2-16H2,1H3,(H2,23,24,25)/t17-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells


J Med Chem 48: 3319-27 (2005)


Article DOI: 10.1021/jm049186t
BindingDB Entry DOI: 10.7270/Q2154GJ4
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3


(Homo sapiens (Human))
BDBM50271700
PNG
(4-(4-(ethoxycarbonyl)styryl)benzenesulfonic acid |...)
Show SMILES CCOC(=O)c1ccc(\C=C\c2ccc(cc2)S(O)(=O)=O)cc1
Show InChI InChI=1S/C17H16O5S/c1-2-22-17(18)15-9-5-13(6-10-15)3-4-14-7-11-16(12-8-14)23(19,20)21/h3-12H,2H2,1H3,(H,19,20,21)/b4-3+
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n/an/an/an/a>1.18E+4n/an/an/an/a



The University of Memphis

Curated by ChEMBL


Assay Description
Agonist activity at LPA3 receptor (unknown origin) expressed in rat RH7777 cells assessed as LPA-induced intracellular calcium response


Bioorg Med Chem 16: 6207-17 (2008)


Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C
More data for this
Ligand-Target Pair