Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50095341 (3,5,7-Trihydroxy-2-(4-octyl-phenyl)-chromen-4-one ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50084981 (8-((E)-3,7-Dimethyl-octa-2,6-dienyl)-3,5,7-trihydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50084975 (6-((E)-3,7-Dimethyl-octa-2,6-dienyl)-3,5,7-trihydr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50084977 (3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50084976 (3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50095339 (3,5,7-Trihydroxy-2-(4-iodo-phenyl)-chromen-4-one |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50095338 (2-(4-Benzhydryl-phenyl)-3,5,7-trihydroxy-chromen-4...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50084979 (3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxy-phenyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50095342 (2-(2,4-Dichloro-phenyl)-3,5,7-trihydroxy-chromen-4...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50084978 (3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50084978 (3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50049391 (3,5,7-Trihydroxyflavone | 3,5,7-triOH-flavone | 3,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM7462 (3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50218276 (Silibinin | Silymarin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50095340 (2-(4-Fluoro-phenyl)-3,5,7-trihydroxy-chromen-4-one...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a |
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL | Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein | Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM23419 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 2.85E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Mus musculus (Mouse)) | BDBM50049400 ((+/-) taxifolin | (+/-)-Dihydroquercetin | (+/-)-t...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.74E+4 | n/a | n/a | n/a | n/a | n/a |
Universit£ Claude Bernard-Lyon 1 Curated by ChEMBL | Assay Description Compound was tested for the binding affinity towards recombinant NBD2 C-terminal cytotoxic nucleotide-binding domain of mouse P-Glycoprotein | Bioorg Med Chem Lett 10: 157-60 (2000) BindingDB Entry DOI: 10.7270/Q2DR2W1W | |||||||||||
More data for this Ligand-Target Pair |