Compile Data Set for Download or QSAR

Found 115 hits Enz. Inhib. hit(s) with all data for entry = 50041211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2257 (2-Pyridinone derivative 37 | 3-{[(4,7-Dichlorobenz...) Show SMILES CCc1cc(SCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H14Cl2N2O2S/c1-3-9-6-12(16(21)19-8(9)2)23-7-13-20-14-10(17)4-5-11(18)15(14)22-13/h4-6H,3,7H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2257 (2-Pyridinone derivative 37 | 3-{[(4,7-Dichlorobenz...) Show SMILES CCc1cc(SCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H14Cl2N2O2S/c1-3-9-6-12(16(21)19-8(9)2)23-7-13-20-14-10(17)4-5-11(18)15(14)22-13/h4-6H,3,7H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2250 (2-Pyridinone derivative 30 | 3-[2-(4-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(F)cccc3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17FN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2250 (2-Pyridinone derivative 30 | 3-[2-(4-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(F)cccc3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17FN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2223 (2-Pyridinone derivative 21 | 3-[2-(4,7-dichloro-1,...) Show SMILES CCc1cc(CCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H16Cl2N2O2/c1-3-10-8-11(17(22)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)23-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2223 (2-Pyridinone derivative 21 | 3-[2-(4,7-dichloro-1,...) Show SMILES CCc1cc(CCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H16Cl2N2O2/c1-3-10-8-11(17(22)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)23-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2242 (2-Pyridinone derivative 22 | 3-[2-(4,7-Difluoroben...) Show SMILES CCc1cc(CCc2nc3c(F)ccc(F)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H16F2N2O2/c1-3-10-8-11(17(22)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)23-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2242 (2-Pyridinone derivative 22 | 3-[2-(4,7-Difluoroben...) Show SMILES CCc1cc(CCc2nc3c(F)ccc(F)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H16F2N2O2/c1-3-10-8-11(17(22)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)23-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2249 (2-Pyridinone derivative 29 | 3-[2-(4,7-Difluoroben...) Show SMILES CCc1cc(CCc2nc3c(F)ccc(F)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H16F2N2OS/c1-3-10-8-11(17(23)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)22-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2236 (2-Pyridinone derivative 16 | 3-[2-(4-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(F)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17FN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2236 (2-Pyridinone derivative 16 | 3-[2-(4-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(F)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17FN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2249 (2-Pyridinone derivative 29 | 3-[2-(4,7-Difluoroben...) Show SMILES CCc1cc(CCc2nc3c(F)ccc(F)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H16F2N2OS/c1-3-10-8-11(17(23)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)22-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM1317 (3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...) Show SMILES CCc1cc(NCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H15Cl2N3O2/c1-3-9-6-12(16(22)20-8(9)2)19-7-13-21-14-10(17)4-5-11(18)15(14)23-13/h4-6,19H,3,7H2,1-2H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM1317 (3-[[(4,7-Dichlorobenzoxazol-2-yl)-methyl]amino]-5-...) Show SMILES CCc1cc(NCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H15Cl2N3O2/c1-3-9-6-12(16(22)20-8(9)2)19-7-13-21-14-10(17)4-5-11(18)15(14)23-13/h4-6,19H,3,7H2,1-2H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2215 (3-[2-(1,3-benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-...) Show SMILES CCc1cc(CCc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H18N2O2/c1-3-12-10-13(17(20)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)21-16/h4-7,10H,3,8-9H2,1-2H3,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2215 (3-[2-(1,3-benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-...) Show SMILES CCc1cc(CCc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H18N2O2/c1-3-12-10-13(17(20)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)21-16/h4-7,10H,3,8-9H2,1-2H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2246 (2-Pyridinone derivative 26 | 3-[2-(1,3-benzoxazol-...) Show SMILES CCc1cc(CCc2nc3ccccc3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H18N2OS/c1-3-12-10-13(17(21)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)20-16/h4-7,10H,3,8-9H2,1-2H3,(H,18,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2246 (2-Pyridinone derivative 26 | 3-[2-(1,3-benzoxazol-...) Show SMILES CCc1cc(CCc2nc3ccccc3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H18N2OS/c1-3-12-10-13(17(21)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)20-16/h4-7,10H,3,8-9H2,1-2H3,(H,18,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2222 (2-Pyridinone derivative 20 | 3-[2-(4,7-dimethyl-1,...) Show SMILES CCc1cc(CCc2nc3c(C)ccc(C)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C19H22N2O2/c1-5-14-10-15(19(22)20-13(14)4)8-9-16-21-17-11(2)6-7-12(3)18(17)23-16/h6-7,10H,5,8-9H2,1-4H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2222 (2-Pyridinone derivative 20 | 3-[2-(4,7-dimethyl-1,...) Show SMILES CCc1cc(CCc2nc3c(C)ccc(C)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C19H22N2O2/c1-5-14-10-15(19(22)20-13(14)4)8-9-16-21-17-11(2)6-7-12(3)18(17)23-16/h6-7,10H,5,8-9H2,1-4H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2253 (2-Pyridinone derivative 33 | 3-[2-(7-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(Cl)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17ClN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2253 (2-Pyridinone derivative 33 | 3-[2-(7-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(Cl)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17ClN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2252 (2-Pyridinone derivative 32 | 3-[2-(4-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(Cl)cccc3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17ClN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2248 (2-Pyridinone derivative 28 | 3-[2-(4,7-Dichloroben...) Show SMILES CCc1cc(CCc2nc3c(Cl)ccc(Cl)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H16Cl2N2OS/c1-3-10-8-11(17(23)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)22-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2252 (2-Pyridinone derivative 32 | 3-[2-(4-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(Cl)cccc3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17ClN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2248 (2-Pyridinone derivative 28 | 3-[2-(4,7-Dichloroben...) Show SMILES CCc1cc(CCc2nc3c(Cl)ccc(Cl)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H16Cl2N2OS/c1-3-10-8-11(17(23)20-9(10)2)4-7-14-21-15-12(18)5-6-13(19)16(15)22-14/h5-6,8H,3-4,7H2,1-2H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2234 (2-Pyridinone derivative 14 | 3-[2-(4-Methylbenzoxa...) Show SMILES CCc1cc(CCc2nc3c(C)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-4-13-10-14(18(21)19-12(13)3)8-9-16-20-17-11(2)6-5-7-15(17)22-16/h5-7,10H,4,8-9H2,1-3H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2234 (2-Pyridinone derivative 14 | 3-[2-(4-Methylbenzoxa...) Show SMILES CCc1cc(CCc2nc3c(C)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-4-13-10-14(18(21)19-12(13)3)8-9-16-20-17-11(2)6-5-7-15(17)22-16/h5-7,10H,4,8-9H2,1-3H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2276 (2-Pyridinone derivative 57 | 3-[2-(4,7-dichloro-1,...) Show SMILES CCCc1cc(CCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H18Cl2N2O2/c1-3-4-11-9-12(18(23)21-10(11)2)5-8-15-22-16-13(19)6-7-14(20)17(16)24-15/h6-7,9H,3-5,8H2,1-2H3,(H,21,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2276 (2-Pyridinone derivative 57 | 3-[2-(4,7-dichloro-1,...) Show SMILES CCCc1cc(CCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H18Cl2N2O2/c1-3-4-11-9-12(18(23)21-10(11)2)5-8-15-22-16-13(19)6-7-14(20)17(16)24-15/h6-7,9H,3-5,8H2,1-2H3,(H,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2239 (2-Pyridinone derivative 19 | 3-[2-(7-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(F)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17FN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2239 (2-Pyridinone derivative 19 | 3-[2-(7-Fluorobenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(F)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17FN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2238 (2-Pyridinone derivative 18 | 3-[2-(7-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17ClN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2238 (2-Pyridinone derivative 18 | 3-[2-(7-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17ClN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2237 (2-Pyridinone derivative 17 | 3-[2-(7-Methylbenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(C)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-4-13-10-14(18(21)19-12(13)3)8-9-16-20-15-7-5-6-11(2)17(15)22-16/h5-7,10H,4,8-9H2,1-3H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2237 (2-Pyridinone derivative 17 | 3-[2-(7-Methylbenzoxa...) Show SMILES CCc1cc(CCc2nc3cccc(C)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-4-13-10-14(18(21)19-12(13)3)8-9-16-20-15-7-5-6-11(2)17(15)22-16/h5-7,10H,4,8-9H2,1-3H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2251 (2-Pyridinone derivative 31 | 3-[ 2-(7-Fluorobenzox...) Show SMILES CCc1cc(CCc2nc3cccc(F)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17FN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2251 (2-Pyridinone derivative 31 | 3-[ 2-(7-Fluorobenzox...) Show SMILES CCc1cc(CCc2nc3cccc(F)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C17H17FN2OS/c1-3-11-9-12(17(22)19-10(11)2)7-8-15-20-14-6-4-5-13(18)16(14)21-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2268 (2-Pyridinone derivative 48 | 3-[2-(1,3-benzoxazol-...) Show SMILES CC(C)c1cc(CCc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-11(2)14-10-13(18(21)19-12(14)3)8-9-17-20-15-6-4-5-7-16(15)22-17/h4-7,10-11H,8-9H2,1-3H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2268 (2-Pyridinone derivative 48 | 3-[2-(1,3-benzoxazol-...) Show SMILES CC(C)c1cc(CCc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-11(2)14-10-13(18(21)19-12(14)3)8-9-17-20-15-6-4-5-7-16(15)22-17/h4-7,10-11H,8-9H2,1-3H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2247 (2-Pyridinone derivative 27 | 3-[2-(4,7-Dimethylben...) Show SMILES CCc1cc(CCc2nc3c(C)ccc(C)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C19H22N2OS/c1-5-14-10-15(19(23)20-13(14)4)8-9-16-21-17-11(2)6-7-12(3)18(17)22-16/h6-7,10H,5,8-9H2,1-4H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2247 (2-Pyridinone derivative 27 | 3-[2-(4,7-Dimethylben...) Show SMILES CCc1cc(CCc2nc3c(C)ccc(C)c3o2)c(=S)[nH]c1C Show InChI InChI=1S/C19H22N2OS/c1-5-14-10-15(19(23)20-13(14)4)8-9-16-21-17-11(2)6-7-12(3)18(17)22-16/h6-7,10H,5,8-9H2,1-4H3,(H,20,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2230 (2-Pyridinone derivative 10 | 3-[2-(4,5,6,7-Tetrahy...) Show SMILES CCc1cc(CCc2nc3CCCCc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H22N2O2/c1-3-12-10-13(17(20)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)21-16/h10H,3-9H2,1-2H3,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50407136 (CHEMBL176463) Show SMILES CCc1cc(CCC2=NC3CCCCC3O2)c(=O)[nH]c1C |t:7| Show InChI InChI=1S/C17H24N2O2/c1-3-12-10-13(17(20)18-11(12)2)8-9-16-19-14-6-4-5-7-15(14)21-16/h10,14-15H,3-9H2,1-2H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2235 (2-Pyridinone derivative 15 | 3-[2-(4-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(Cl)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17ClN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2235 (2-Pyridinone derivative 15 | 3-[2-(4-Chlorobenzoxa...) Show SMILES CCc1cc(CCc2nc3c(Cl)cccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C17H17ClN2O2/c1-3-11-9-12(17(21)19-10(11)2)7-8-15-20-16-13(18)5-4-6-14(16)22-15/h4-6,9H,3,7-8H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2267 (2-Pyridinone derivative 47 | 3-[2-(1,3-benzoxazol-...) Show SMILES CCCc1cc(CCc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-3-6-13-11-14(18(21)19-12(13)2)9-10-17-20-15-7-4-5-8-16(15)22-17/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2267 (2-Pyridinone derivative 47 | 3-[2-(1,3-benzoxazol-...) Show SMILES CCCc1cc(CCc2nc3ccccc3o2)c(=O)[nH]c1C Show InChI InChI=1S/C18H20N2O2/c1-3-6-13-11-14(18(21)19-12(13)2)9-10-17-20-15-7-4-5-8-16(15)22-17/h4-5,7-8,11H,3,6,9-10H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2256 (2-Pyridinone derivative 36 | 3-[(4,7-Dichlorobenzo...) Show SMILES CCc1cc(OCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H14Cl2N2O3/c1-3-9-6-12(16(21)19-8(9)2)22-7-13-20-14-10(17)4-5-11(18)15(14)23-13/h4-6H,3,7H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2256 (2-Pyridinone derivative 36 | 3-[(4,7-Dichlorobenzo...) Show SMILES CCc1cc(OCc2nc3c(Cl)ccc(Cl)c3o2)c(=O)[nH]c1C Show InChI InChI=1S/C16H14Cl2N2O3/c1-3-9-6-12(16(21)19-8(9)2)22-7-13-20-14-10(17)4-5-11(18)15(14)23-13/h4-6H,3,7H2,1-2H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair

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