Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with all data for entry = 8429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247467 (US9453023, 26) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2c(C)noc2C)cc1 |r| Show InChI InChI=1S/C22H29N3O2/c1-14-5-4-12-25(14)20-11-8-18(13-20)17-6-9-19(10-7-17)23-22(26)21-15(2)24-27-16(21)3/h6-7,9-10,14,18,20H,4-5,8,11-13H2,1-3H3,(H,23,26)/t14-,18-,20?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247449 (US9453023, 8) Show SMILES CC1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCCC2(CCNCC2)C1=O |r| Show InChI InChI=1S/C25H37N3O/c1-19-4-2-16-27(19)23-10-7-21(18-23)20-5-8-22(9-6-20)28-17-3-11-25(24(28)29)12-14-26-15-13-25/h5-6,8-9,19,21,23,26H,2-4,7,10-18H2,1H3/t19?,21-,23?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247453 (US9453023, 12) Show SMILES C[C@H]1CCCN1[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCC2(CCOCC2)C1=O |r,wU:9.13,wD:6.6,1.0,(6.5,-3.36,;7.27,-2.02,;8.74,-1.55,;8.74,-.01,;7.27,.47,;6.37,-.78,;4.83,-.78,;4.06,.56,;2.52,.56,;1.75,-.78,;2.52,-2.11,;4.06,-2.11,;.21,-.78,;-.56,-2.11,;-2.1,-2.11,;-2.87,-.78,;-2.1,.56,;-.56,.56,;-4.41,-.78,;-5.66,-1.68,;-6.9,-.78,;-6.43,.69,;-5.66,2.02,;-6.43,3.36,;-7.97,3.36,;-8.74,2.02,;-7.97,.69,;-4.89,.69,;-4.12,2.02,)| Show InChI InChI=1S/C25H36N2O2/c1-19-3-2-15-26(19)22-8-4-20(5-9-22)21-6-10-23(11-7-21)27-16-12-25(24(27)28)13-17-29-18-14-25/h6-7,10-11,19-20,22H,2-5,8-9,12-18H2,1H3/t19-,20-,22-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247455 (US9453023, 14) Show SMILES C[C@@H]1CCCN1[C@H]1CC[C@@H](CC1)c1ccc(N2CCC3(CCN(CC3)C(=O)OC(C)(C)C)C2=O)c(F)c1 |r,wU:9.13,1.0,wD:6.6,(9.66,-3.21,;10.43,-1.88,;11.9,-1.41,;11.9,.13,;10.43,.61,;9.53,-.64,;7.99,-.64,;7.22,.7,;5.68,.7,;4.91,-.64,;5.68,-1.97,;7.22,-1.97,;3.37,-.64,;2.6,-1.97,;1.06,-1.97,;.29,-.64,;-1.25,-.64,;-1.73,-2.1,;-3.27,-2.1,;-3.74,-.64,;-5.08,-1.41,;-6.41,-.64,;-6.41,.9,;-5.08,1.67,;-3.74,.9,;-7.74,1.67,;-7.74,3.21,;-9.08,.9,;-10.41,1.67,;-10.81,3.16,;-11.9,2.07,;-11.5,.59,;-2.5,.27,;-2.5,1.81,;1.06,.7,;.29,2.03,;2.6,.7,)| Show InChI InChI=1S/C30H44FN3O3/c1-21-6-5-16-33(21)24-10-7-22(8-11-24)23-9-12-26(25(31)20-23)34-19-15-30(27(34)35)13-17-32(18-14-30)28(36)37-29(2,3)4/h9,12,20-22,24H,5-8,10-11,13-19H2,1-4H3/t21-,22-,24-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247462 (US9453023, 21) Show SMILES C[C@H]1CCCN1C1CCC(=CC1)c1ccc(NC(=O)OCc2ccccc2)c(F)c1 |r,c:10| Show InChI InChI=1S/C25H29FN2O2/c1-18-6-5-15-28(18)22-12-9-20(10-13-22)21-11-14-24(23(26)16-21)27-25(29)30-17-19-7-3-2-4-8-19/h2-4,7-9,11,14,16,18,22H,5-6,10,12-13,15,17H2,1H3,(H,27,29)/t18-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247459 (US9453023, 18) Show SMILES C[C@@H]1CCCN1[C@H]1CC[C@@H](CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1 |r,wU:9.13,1.0,wD:6.6,(6.45,-2.62,;7.22,-1.29,;8.68,-.81,;8.68,.73,;7.22,1.2,;6.31,-.04,;4.77,-.04,;4,1.29,;2.46,1.29,;1.69,-.04,;2.46,-1.38,;4,-1.38,;.15,-.04,;-.62,-1.38,;-2.16,-1.38,;-2.93,-.04,;-4.47,-.04,;-4.94,-1.51,;-6.48,-1.51,;-6.96,-.04,;-8.29,-.81,;-9.63,-.04,;-9.63,1.5,;-8.29,2.27,;-6.96,1.5,;-5.71,.86,;-5.71,2.4,;-2.16,1.29,;-2.93,2.62,;-.62,1.29,)| Show InChI InChI=1S/C25H36FN3O/c1-18-3-2-15-28(18)21-7-4-19(5-8-21)20-6-9-23(22(26)17-20)29-16-12-25(24(29)30)10-13-27-14-11-25/h6,9,17-19,21,27H,2-5,7-8,10-16H2,1H3/t18-,19-,21-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247442 (US9453023, 1) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCC2(CCOCC2)C1=O |r| Show InChI InChI=1S/C24H34N2O2/c1-18-3-2-13-25(18)22-9-6-20(17-22)19-4-7-21(8-5-19)26-14-10-24(23(26)27)11-15-28-16-12-24/h4-5,7-8,18,20,22H,2-3,6,9-17H2,1H3/t18-,20-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247465 (US9453023, 24) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C22H27FN2O2S/c1-16-3-2-14-25(16)21-11-6-18(15-21)17-4-9-20(10-5-17)24-28(26,27)22-12-7-19(23)8-13-22/h4-5,7-10,12-13,16,18,21,24H,2-3,6,11,14-15H2,1H3/t16-,18-,21?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247443 (US9453023, 2) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCC2(CCCCC2)C1=O |r| Show InChI InChI=1S/C25H36N2O/c1-19-6-5-16-26(19)23-12-9-21(18-23)20-7-10-22(11-8-20)27-17-15-25(24(27)28)13-3-2-4-14-25/h7-8,10-11,19,21,23H,2-6,9,12-18H2,1H3/t19-,21-,23?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247444 (US9453023, 3) Show SMILES CC1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCCC2(CCN(CC2)C(=O)OC(C)(C)C)C1=O |r| Show InChI InChI=1S/C30H45N3O3/c1-22-7-5-17-32(22)26-13-10-24(21-26)23-8-11-25(12-9-23)33-18-6-14-30(27(33)34)15-19-31(20-16-30)28(35)36-29(2,3)4/h8-9,11-12,22,24,26H,5-7,10,13-21H2,1-4H3/t22?,24-,26?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	17.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247447 (US9453023, 6) Show SMILES CC1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCC2(CCN(CC2)C(=O)OC(C)(C)C)C1=O |r| Show InChI InChI=1S/C29H43N3O3/c1-21-6-5-16-31(21)25-12-9-23(20-25)22-7-10-24(11-8-22)32-19-15-29(26(32)33)13-17-30(18-14-29)27(34)35-28(2,3)4/h7-8,10-11,21,23,25H,5-6,9,12-20H2,1-4H3/t21?,23-,25?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	26.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247471 (US9453023, 30) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NS(=O)(=O)c2ccc(F)c(F)c2)cc1 |r| Show InChI InChI=1S/C22H26F2N2O2S/c1-15-3-2-12-26(15)19-9-6-17(13-19)16-4-7-18(8-5-16)25-29(27,28)20-10-11-21(23)22(24)14-20/h4-5,7-8,10-11,14-15,17,19,25H,2-3,6,9,12-13H2,1H3/t15-,17-,19?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	27.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247448 (US9453023, 7) Show SMILES CC1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCCC2(CCCC2)C1=O |r| Show InChI InChI=1S/C25H36N2O/c1-19-6-4-16-26(19)23-12-9-21(18-23)20-7-10-22(11-8-20)27-17-5-15-25(24(27)28)13-2-3-14-25/h7-8,10-11,19,21,23H,2-6,9,12-18H2,1H3/t19?,21-,23?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	27.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247474 (US9453023, 33) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccccc2C)cc1 |r| Show InChI InChI=1S/C24H30N2O/c1-17-6-3-4-8-23(17)24(27)25-21-12-9-19(10-13-21)20-11-14-22(16-20)26-15-5-7-18(26)2/h3-4,6,8-10,12-13,18,20,22H,5,7,11,14-16H2,1-2H3,(H,25,27)/t18-,20-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	32.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247469 (US9453023, 28) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)C2CCOCC2)cc1 |r| Show InChI InChI=1S/C22H32N2O2/c1-16-3-2-12-24(16)21-9-6-19(15-21)17-4-7-20(8-5-17)23-22(25)18-10-13-26-14-11-18/h4-5,7-8,16,18-19,21H,2-3,6,9-15H2,1H3,(H,23,25)/t16-,19-,21?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	33.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247468 (US9453023, 27) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NS(=O)(=O)C2CC2)cc1 |r| Show InChI InChI=1S/C19H28N2O2S/c1-14-3-2-12-21(14)18-9-6-16(13-18)15-4-7-17(8-5-15)20-24(22,23)19-10-11-19/h4-5,7-8,14,16,18-20H,2-3,6,9-13H2,1H3/t14-,16-,18?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247472 (US9453023, 31) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccc(F)cc2)cc1 |r| Show InChI InChI=1S/C23H27FN2O/c1-16-3-2-14-26(16)22-13-8-19(15-22)17-6-11-21(12-7-17)25-23(27)18-4-9-20(24)10-5-18/h4-7,9-12,16,19,22H,2-3,8,13-15H2,1H3,(H,25,27)/t16-,19-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	34.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247451 (US9453023, 10) Show SMILES C[C@@H]1CCCN1[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCC2(CCOCC2)C1=O |r,wU:9.13,1.0,wD:6.6,(6.5,-3.36,;7.27,-2.02,;8.74,-1.55,;8.74,-.01,;7.27,.47,;6.37,-.78,;4.83,-.78,;4.06,.56,;2.52,.56,;1.75,-.78,;2.52,-2.11,;4.06,-2.11,;.21,-.78,;-.56,-2.11,;-2.1,-2.11,;-2.87,-.78,;-2.1,.56,;-.56,.56,;-4.41,-.78,;-5.66,-1.68,;-6.9,-.78,;-6.43,.69,;-5.66,2.02,;-6.43,3.36,;-7.97,3.36,;-8.74,2.02,;-7.97,.69,;-4.89,.69,;-4.12,2.02,)| Show InChI InChI=1S/C25H36N2O2/c1-19-3-2-15-26(19)22-8-4-20(5-9-22)21-6-10-23(11-7-21)27-16-12-25(24(27)28)13-17-29-18-14-25/h6-7,10-11,19-20,22H,2-5,8-9,12-18H2,1H3/t19-,20-,22-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	35.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247441 (US9453023, Intermediate (13)) Show SMILES C[C@@H]1CCCN1C1CC[C@H](C1)c1ccc(NC(=O)OCc2ccccc2)cc1 Show InChI InChI=1S/C24H30N2O2/c1-18-6-5-15-26(18)23-14-11-21(16-23)20-9-12-22(13-10-20)25-24(27)28-17-19-7-3-2-4-8-19/h2-4,7-10,12-13,18,21,23H,5-6,11,14-17H2,1H3,(H,25,27)/t18-,21-,23?/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247452 (US9453023, 11) Show SMILES C[C@H]1CCCCN1[C@H]1CC[C@@H](CC1)c1ccc(cc1)N1CCC2(CCOCC2)C1=O |r,wU:10.14,wD:7.7,1.0,(6.01,-3.4,;6.78,-2.07,;8.32,-2.07,;9.09,-.73,;8.32,.6,;6.78,.6,;6.01,-.73,;4.47,-.73,;3.7,.6,;2.16,.6,;1.39,-.73,;2.16,-2.07,;3.7,-2.07,;-.15,-.73,;-.92,-2.07,;-2.46,-2.07,;-3.23,-.73,;-2.46,.6,;-.92,.6,;-4.77,-.73,;-6.01,-1.64,;-7.26,-.73,;-6.78,.73,;-6.01,2.07,;-6.78,3.4,;-8.32,3.4,;-9.09,2.07,;-8.32,.73,;-5.24,.73,;-4.47,2.07,)| Show InChI InChI=1S/C26H38N2O2/c1-20-4-2-3-16-27(20)23-9-5-21(6-10-23)22-7-11-24(12-8-22)28-17-13-26(25(28)29)14-18-30-19-15-26/h7-8,11-12,20-21,23H,2-6,9-10,13-19H2,1H3/t20-,21-,23-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	39.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247446 (US9453023, 5) Show SMILES COC(=O)C1CCC2(CCN(C2=O)c2ccc(cc2)[C@H]2CCC(C2)N2CCCC2C)CC1 |r| Show InChI InChI=1S/C27H38N2O3/c1-19-4-3-16-28(19)24-10-7-22(18-24)20-5-8-23(9-6-20)29-17-15-27(26(29)31)13-11-21(12-14-27)25(30)32-2/h5-6,8-9,19,21-22,24H,3-4,7,10-18H2,1-2H3/t19?,21?,22-,24?,27?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	44.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247457 (US9453023, 16) Show SMILES C[C@H]1CCCN1[C@H]1CC[C@@H](CC1)c1ccc(N2CCC3(CCN(CC3)C(=O)OC(C)(C)C)C2=O)c(F)c1 |r,wU:9.13,wD:6.6,1.0,(9.66,-3.21,;10.43,-1.88,;11.9,-1.41,;11.9,.13,;10.43,.61,;9.53,-.64,;7.99,-.64,;7.22,.7,;5.68,.7,;4.91,-.64,;5.68,-1.97,;7.22,-1.97,;3.37,-.64,;2.6,-1.97,;1.06,-1.97,;.29,-.64,;-1.25,-.64,;-1.73,-2.1,;-3.27,-2.1,;-3.74,-.64,;-5.08,-1.41,;-6.41,-.64,;-6.41,.9,;-5.08,1.67,;-3.74,.9,;-7.74,1.67,;-7.74,3.21,;-9.08,.9,;-10.41,1.67,;-10.81,3.16,;-11.9,2.07,;-11.5,.59,;-2.5,.27,;-2.5,1.81,;1.06,.7,;.29,2.03,;2.6,.7,)| Show InChI InChI=1S/C30H44FN3O3/c1-21-6-5-16-33(21)24-10-7-22(8-11-24)23-9-12-26(25(31)20-23)34-19-15-30(27(34)35)13-17-32(18-14-30)28(36)37-29(2,3)4/h9,12,20-22,24H,5-8,10-11,13-19H2,1-4H3/t21-,22-,24-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	44.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247466 (US9453023, 25) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NOc2cc(F)ccc2C)cc1 |r| Show InChI InChI=1S/C23H29FN2O/c1-16-5-9-20(24)15-23(16)27-25-21-10-6-18(7-11-21)19-8-12-22(14-19)26-13-3-4-17(26)2/h5-7,9-11,15,17,19,22,25H,3-4,8,12-14H2,1-2H3/t17-,19-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	45.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247464 (US9453023, 23) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2cccs2)cc1 |r| Show InChI InChI=1S/C21H26N2OS/c1-15-4-2-12-23(15)19-11-8-17(14-19)16-6-9-18(10-7-16)22-21(24)20-5-3-13-25-20/h3,5-7,9-10,13,15,17,19H,2,4,8,11-12,14H2,1H3,(H,22,24)/t15-,17-,19?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	46.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247477 (US9453023, 36) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccc(OC(F)(F)F)cc2)cc1 |r| Show InChI InChI=1S/C24H27F3N2O2/c1-16-3-2-14-29(16)21-11-6-19(15-21)17-4-9-20(10-5-17)28-23(30)18-7-12-22(13-8-18)31-24(25,26)27/h4-5,7-10,12-13,16,19,21H,2-3,6,11,14-15H2,1H3,(H,28,30)/t16-,19-,21?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	48.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247440 (US9453023, Intermediate (10)) Show SMILES CC1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)OCc2ccccc2)cc1 |r| Show InChI InChI=1S/C24H30N2O2/c1-18-6-5-15-26(18)23-14-11-21(16-23)20-9-12-22(13-10-20)25-24(27)28-17-19-7-3-2-4-8-19/h2-4,7-10,12-13,18,21,23H,5-6,11,14-17H2,1H3,(H,25,27)/t18?,21-,23?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	65.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247473 (US9453023, 32) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C23H27ClN2O/c1-16-3-2-14-26(16)22-13-8-19(15-22)17-6-11-21(12-7-17)25-23(27)18-4-9-20(24)10-5-18/h4-7,9-12,16,19,22H,2-3,8,13-15H2,1H3,(H,25,27)/t16-,19-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	65.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247478 (US9453023, 37) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C24H30N2O/c1-18-6-5-15-26(18)23-14-11-21(17-23)20-9-12-22(13-10-20)25-24(27)16-19-7-3-2-4-8-19/h2-4,7-10,12-13,18,21,23H,5-6,11,14-17H2,1H3,(H,25,27)/t18-,21-,23?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	71.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247445 (US9453023, 4) Show SMILES CC1CCCN1C1CC[C@@H](C1)c1ccc(cc1)N1CCC2(CCC(O)CC2)C1=O |r,wU:9.12,(5.29,-3.56,;6.63,-2.79,;8.09,-3.26,;9,-2.02,;8.09,-.77,;6.63,-1.25,;5.29,-.48,;5.29,1.06,;3.83,1.54,;2.92,.29,;3.83,-.95,;1.38,.29,;.61,-1.04,;-.93,-1.04,;-1.7,.29,;-.93,1.63,;.61,1.63,;-3.24,.29,;-3.71,-1.17,;-5.25,-1.17,;-5.73,.29,;-5.33,1.78,;-6.42,2.87,;-7.91,2.47,;-9,3.56,;-8.31,.98,;-7.22,-.11,;-4.48,1.2,;-4.48,2.74,)| Show InChI InChI=1S/C25H36N2O2/c1-18-3-2-15-26(18)22-9-6-20(17-22)19-4-7-21(8-5-19)27-16-14-25(24(27)29)12-10-23(28)11-13-25/h4-5,7-8,18,20,22-23,28H,2-3,6,9-17H2,1H3/t18?,20-,22?,23?,25?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	75.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247470 (US9453023, 29) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccccc2)cc1 |r| Show InChI InChI=1S/C23H28N2O/c1-17-6-5-15-25(17)22-14-11-20(16-22)18-9-12-21(13-10-18)24-23(26)19-7-3-2-4-8-19/h2-4,7-10,12-13,17,20,22H,5-6,11,14-16H2,1H3,(H,24,26)/t17-,20-,22?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	75.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247460 (US9453023, 19) Show SMILES Fc1cc(ccc1N1CCC2(CCNCC2)C1=O)[C@H]1CC[C@@H](CC1)N1CCC1 |r,wU:18.20,wD:21.27,(-2.83,2.07,;-2.06,.73,;-.52,.73,;.25,-.6,;-.52,-1.93,;-2.06,-1.93,;-2.83,-.6,;-4.37,-.6,;-4.85,-2.07,;-6.39,-2.07,;-6.86,-.6,;-8.2,-1.37,;-9.53,-.6,;-9.53,.94,;-8.2,1.71,;-6.86,.94,;-5.62,.3,;-5.62,1.84,;1.79,-.6,;2.56,.73,;4.1,.73,;4.87,-.6,;4.1,-1.93,;2.56,-1.93,;6.41,-.6,;7.5,-1.69,;8.59,-.6,;7.5,.49,)| Show InChI InChI=1S/C23H32FN3O/c24-20-16-18(17-2-5-19(6-3-17)26-13-1-14-26)4-7-21(20)27-15-10-23(22(27)28)8-11-25-12-9-23/h4,7,16-17,19,25H,1-3,5-6,8-15H2/t17-,19-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	82.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247458 (US9453023, 17) Show SMILES C[C@H]1CCCN1[C@H]1CC[C@@H](CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(F)c1 |r,wU:9.13,wD:6.6,1.0,(6.45,-2.62,;7.22,-1.29,;8.68,-.81,;8.68,.73,;7.22,1.2,;6.31,-.04,;4.77,-.04,;4,1.29,;2.46,1.29,;1.69,-.04,;2.46,-1.38,;4,-1.38,;.15,-.04,;-.62,-1.38,;-2.16,-1.38,;-2.93,-.04,;-4.47,-.04,;-4.94,-1.51,;-6.48,-1.51,;-6.96,-.04,;-8.29,-.81,;-9.63,-.04,;-9.63,1.5,;-8.29,2.27,;-6.96,1.5,;-5.71,.86,;-5.71,2.4,;-2.16,1.29,;-2.93,2.62,;-.62,1.29,)| Show InChI InChI=1S/C25H36FN3O/c1-18-3-2-15-28(18)21-7-4-19(5-8-21)20-6-9-23(22(26)17-20)29-16-12-25(24(29)30)10-13-27-14-11-25/h6,9,17-19,21,27H,2-5,7-8,10-16H2,1H3/t18-,19-,21-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	84.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247475 (US9453023, 34) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccc(C)cc2)cc1 |r| Show InChI InChI=1S/C24H30N2O/c1-17-5-7-20(8-6-17)24(27)25-22-12-9-19(10-13-22)21-11-14-23(16-21)26-15-3-4-18(26)2/h5-10,12-13,18,21,23H,3-4,11,14-16H2,1-2H3,(H,25,27)/t18-,21-,23?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	98.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247450 (US9453023, 9) Show SMILES O=C1N(CCC11CCOCC1)c1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCCC1 |r,wU:17.19,wD:20.26,(-4.12,1.4,;-4.89,.07,;-4.41,-1.4,;-5.66,-2.3,;-6.9,-1.4,;-6.43,.07,;-5.66,1.4,;-6.43,2.73,;-7.97,2.73,;-8.74,1.4,;-7.97,.07,;-2.87,-1.4,;-2.1,-2.73,;-.56,-2.73,;.21,-1.4,;-.56,-.07,;-2.1,-.07,;1.75,-1.4,;2.52,-.07,;4.06,-.07,;4.83,-1.4,;4.06,-2.73,;2.52,-2.73,;6.37,-1.4,;7.27,-2.65,;8.74,-2.17,;8.74,-.63,;7.27,-.15,)| Show InChI InChI=1S/C24H34N2O2/c27-23-24(12-17-28-18-13-24)11-16-26(23)22-9-5-20(6-10-22)19-3-7-21(8-4-19)25-14-1-2-15-25/h5-6,9-10,19,21H,1-4,7-8,11-18H2/t19-,21-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247463 (US9453023, 22) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)C2CCN(CC2)C(C)=O)cc1 |r| Show InChI InChI=1S/C24H35N3O2/c1-17-4-3-13-27(17)23-10-7-21(16-23)19-5-8-22(9-6-19)25-24(29)20-11-14-26(15-12-20)18(2)28/h5-6,8-9,17,20-21,23H,3-4,7,10-16H2,1-2H3,(H,25,29)/t17-,21-,23?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247476 (US9453023, 35) Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccccc2OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C24H27F3N2O2/c1-16-5-4-14-29(16)20-13-10-18(15-20)17-8-11-19(12-9-17)28-23(30)21-6-2-3-7-22(21)31-24(25,26)27/h2-3,6-9,11-12,16,18,20H,4-5,10,13-15H2,1H3,(H,28,30)/t16-,18-,20?/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247461 (US9453023, 20) Show SMILES Fc1cc(ccc1N1CCC2(CCNCC2)C1=O)[C@H]1CC[C@@H](CC1)N1CCCC1 |r,wU:18.20,wD:21.27,(-2.87,2.07,;-2.1,.73,;-.56,.73,;.21,-.6,;-.56,-1.93,;-2.1,-1.93,;-2.87,-.6,;-4.41,-.6,;-4.88,-2.07,;-6.42,-2.07,;-6.9,-.6,;-8.23,-1.37,;-9.57,-.6,;-9.57,.94,;-8.23,1.71,;-6.9,.94,;-5.65,.3,;-5.65,1.84,;1.75,-.6,;2.52,.73,;4.06,.73,;4.83,-.6,;4.06,-1.93,;2.52,-1.93,;6.37,-.6,;7.28,-1.85,;8.74,-1.37,;8.74,.17,;7.28,.64,)| Show InChI InChI=1S/C24H34FN3O/c25-21-17-19(18-3-6-20(7-4-18)27-14-1-2-15-27)5-8-22(21)28-16-11-24(23(28)29)9-12-26-13-10-24/h5,8,17-18,20,26H,1-4,6-7,9-16H2/t18-,20-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247456 (US9453023, 15) Show SMILES CC(C)(C)OC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2F)[C@H]2CC[C@@H](CC2)N2CCC2)CC1 |r,wU:23.24,wD:26.31,(-10.71,2.6,;-10.32,1.12,;-11.8,1.52,;-11.4,.03,;-8.98,.35,;-7.65,1.12,;-7.65,2.66,;-6.31,.35,;-6.31,-1.19,;-4.98,-1.96,;-3.65,-1.19,;-3.17,-2.66,;-1.63,-2.66,;-1.16,-1.19,;-2.4,-.29,;-2.4,1.25,;.38,-1.19,;1.15,-2.53,;2.69,-2.53,;3.46,-1.19,;2.69,.14,;1.15,.14,;.38,1.47,;5,-1.19,;5.77,.14,;7.31,.14,;8.08,-1.19,;7.31,-2.53,;5.77,-2.53,;9.62,-1.19,;10.71,-2.28,;11.8,-1.19,;10.71,-.1,;-3.65,.35,;-4.98,1.12,)| Show InChI InChI=1S/C28H40FN3O3/c1-27(2,3)35-26(34)31-16-11-28(12-17-31)13-18-32(25(28)33)24-10-7-21(19-23(24)29)20-5-8-22(9-6-20)30-14-4-15-30/h7,10,19-20,22H,4-6,8-9,11-18H2,1-3H3/t20-,22-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair
Histamine receptor H3 (Macaca mulatta (Rhesus macaque))	BDBM247454 (US9453023, 13) Show SMILES CC(C)(C)OC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2F)[C@H]2CC[C@@H](CC2)N2CCCC2)CC1 |r,wU:23.24,wD:26.31,(-10.81,2.6,;-10.41,1.12,;-11.9,1.52,;-11.5,.03,;-9.08,.35,;-7.74,1.12,;-7.74,2.66,;-6.41,.35,;-6.41,-1.19,;-5.08,-1.96,;-3.74,-1.19,;-3.27,-2.66,;-1.73,-2.66,;-1.25,-1.19,;-2.5,-.29,;-2.5,1.25,;.29,-1.19,;1.06,-2.53,;2.6,-2.53,;3.37,-1.19,;2.6,.14,;1.06,.14,;.29,1.47,;4.91,-1.19,;5.68,.14,;7.22,.14,;7.99,-1.19,;7.22,-2.53,;5.68,-2.53,;9.53,-1.19,;10.43,-2.44,;11.9,-1.96,;11.9,-.42,;10.43,.05,;-3.74,.35,;-5.08,1.12,)| Show InChI InChI=1S/C29H42FN3O3/c1-28(2,3)36-27(35)32-17-12-29(13-18-32)14-19-33(26(29)34)25-11-8-22(20-24(25)30)21-6-9-23(10-7-21)31-15-4-5-16-31/h8,11,20-21,23H,4-7,9-10,12-19H2,1-3H3/t21-,23-	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	379	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...				US Patent US9453023 (2016) BindingDB Entry DOI: 10.7270/Q2XD10MK
					More data for this Ligand-Target Pair