Compile Data Set for Download or QSAR

Found 128 hits Enz. Inhib. hit(s) with all data for entry = 50031497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50314225 ((R)-4-acetamido-2-(biphenyl-4-ylsulfonamido)-N-hyd...) Show SMILES CC(=O)NCC[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C18H21N3O5S/c1-13(22)19-12-11-17(18(23)20-24)21-27(25,26)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10,17,21,24H,11-12H2,1H3,(H,19,22)(H,20,23)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50314221 ((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...) Show SMILES ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NS(=O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C18H16BrN3O6S/c19-11-5-7-12(8-6-11)29(27,28)21-15(16(23)20-26)9-10-22-17(24)13-3-1-2-4-14(13)18(22)25/h1-8,15,21,26H,9-10H2,(H,20,23)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50314221 ((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...) Show SMILES ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NS(=O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C18H16BrN3O6S/c19-11-5-7-12(8-6-11)29(27,28)21-15(16(23)20-26)9-10-22-17(24)13-3-1-2-4-14(13)18(22)25/h1-8,15,21,26H,9-10H2,(H,20,23)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50314221 ((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...) Show SMILES ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NS(=O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C18H16BrN3O6S/c19-11-5-7-12(8-6-11)29(27,28)21-15(16(23)20-26)9-10-22-17(24)13-3-1-2-4-14(13)18(22)25/h1-8,15,21,26H,9-10H2,(H,20,23)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50294120 (2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C14H14N2O4S/c17-14(16-18)10-15-21(19,20)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,15,18H,10H2,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human SKOV3 cells assessed as inhibition of EGF-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50314221 ((R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoin...) Show SMILES ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NS(=O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C18H16BrN3O6S/c19-11-5-7-12(8-6-11)29(27,28)21-15(16(23)20-26)9-10-22-17(24)13-3-1-2-4-14(13)18(22)25/h1-8,15,21,26H,9-10H2,(H,20,23)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP1 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human SKOV3 cells assessed as inhibition of EGF-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM13080 (CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO Show InChI InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50314228 ((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C16H26N2O5S/c1-11(2)10-18(15(12(3)4)16(19)17-20)24(21,22)14-8-6-13(23-5)7-9-14/h6-9,11-12,15,20H,10H2,1-5H3,(H,17,19)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50314225 ((R)-4-acetamido-2-(biphenyl-4-ylsulfonamido)-N-hyd...) Show SMILES CC(=O)NCC[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C18H21N3O5S/c1-13(22)19-12-11-17(18(23)20-24)21-27(25,26)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10,17,21,24H,11-12H2,1H3,(H,19,22)(H,20,23)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50294119 (CHEMBL561625 | N-hydroxy-2-(N-isobutylbiphenyl-4-y...) Show SMILES CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H22N2O4S/c1-14(2)12-20(13-18(21)19-22)25(23,24)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14,22H,12-13H2,1-2H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50161331 (2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...) Show SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50314224 ((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C26H29N3O7S/c1-4-5-16-36-19-10-12-20(13-11-19)37(34,35)29(17-18(2)3)23(24(30)27-33)14-15-28-25(31)21-8-6-7-9-22(21)26(28)32/h6-13,18,23,33H,14-17H2,1-3H3,(H,27,30)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM13080 (CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO Show InChI InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM13080 (CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO Show InChI InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human A2774 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50314228 ((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C16H26N2O5S/c1-11(2)10-18(15(12(3)4)16(19)17-20)24(21,22)14-8-6-13(23-5)7-9-14/h6-9,11-12,15,20H,10H2,1-5H3,(H,17,19)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50314224 ((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C26H29N3O7S/c1-4-5-16-36-19-10-12-20(13-11-19)37(34,35)29(17-18(2)3)23(24(30)27-33)14-15-28-25(31)21-8-6-7-9-22(21)26(28)32/h6-13,18,23,33H,14-17H2,1-3H3,(H,27,30)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50314228 ((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C16H26N2O5S/c1-11(2)10-18(15(12(3)4)16(19)17-20)24(21,22)14-8-6-13(23-5)7-9-14/h6-9,11-12,15,20H,10H2,1-5H3,(H,17,19)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50314224 ((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C26H29N3O7S/c1-4-5-16-36-19-10-12-20(13-11-19)37(34,35)29(17-18(2)3)23(24(30)27-33)14-15-28-25(31)21-8-6-7-9-22(21)26(28)32/h6-13,18,23,33H,14-17H2,1-3H3,(H,27,30)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM11328 (CHEMBL83508 | Hydroxamate 9 | N-hydroxy-2-[(4-meth...) Show SMILES COc1ccc(cc1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C9H12N2O5S/c1-16-7-2-4-8(5-3-7)17(14,15)10-6-9(12)11-13/h2-5,10,13H,6H2,1H3,(H,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50294120 (2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C14H14N2O4S/c17-14(16-18)10-15-21(19,20)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,15,18H,10H2,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50314225 ((R)-4-acetamido-2-(biphenyl-4-ylsulfonamido)-N-hyd...) Show SMILES CC(=O)NCC[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C18H21N3O5S/c1-13(22)19-12-11-17(18(23)20-24)21-27(25,26)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10,17,21,24H,11-12H2,1H3,(H,19,22)(H,20,23)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50294119 (CHEMBL561625 | N-hydroxy-2-(N-isobutylbiphenyl-4-y...) Show SMILES CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C18H22N2O4S/c1-14(2)12-20(13-18(21)19-22)25(23,24)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14,22H,12-13H2,1-2H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50314226 (2-(4-bromophenylsulfonamido)-N-hydroxyacetamide | ...) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C8H9BrN2O4S/c9-6-1-3-7(4-2-6)16(14,15)10-5-8(12)11-13/h1-4,10,13H,5H2,(H,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP2 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human MCF7 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human MCF7 cells assessed as inhibition of pervanadate-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50314228 ((R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfona...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C16H26N2O5S/c1-11(2)10-18(15(12(3)4)16(19)17-20)24(21,22)14-8-6-13(23-5)7-9-14/h6-9,11-12,15,20H,10H2,1-5H3,(H,17,19)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP1 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP1 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314224 ((R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonami...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C26H29N3O7S/c1-4-5-16-36-19-10-12-20(13-11-19)37(34,35)29(17-18(2)3)23(24(30)27-33)14-15-28-25(31)21-8-6-7-9-22(21)26(28)32/h6-13,18,23,33H,14-17H2,1-3H3,(H,27,30)/t23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50294120 (2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C14H14N2O4S/c17-14(16-18)10-15-21(19,20)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,15,18H,10H2,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP14 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human GI-CA-N cells assessed as inhibition of pervanadate-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human GI-CA-N cells assessed as inhibition of constitutive sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314223 ((R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO |r| Show InChI InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human GI-CA-N cells assessed as inhibition of constitutive sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM8465 ((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human SKOV3 cells assessed as inhibition of EGF-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314220 ((R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hyd...) Show SMILES CC(=O)NCC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C(=O)NO |r| Show InChI InChI=1S/C12H16BrN3O5S/c1-8(17)14-7-6-11(12(18)15-19)16-22(20,21)10-4-2-9(13)3-5-10/h2-5,11,16,19H,6-7H2,1H3,(H,14,17)(H,15,18)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant ADAM17 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50314222 ((R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-...) Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of ADAM17 in human MDA-MB-468 cells assessed as inhibition of EGF-induced sALCAM release by ELISA				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM11328 (CHEMBL83508 | Hydroxamate 9 | N-hydroxy-2-[(4-meth...) Show SMILES COc1ccc(cc1)S(=O)(=O)NCC(=O)NO Show InChI InChI=1S/C9H12N2O5S/c1-16-7-2-4-8(5-3-7)17(14,15)10-6-9(12)11-13/h2-5,10,13H,6H2,1H3,(H,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of MMP9 by fluorometric assay				J Med Chem 53: 2622-35 (2010) Article DOI: 10.1021/jm901868z BindingDB Entry DOI: 10.7270/Q26H4HK0
					More data for this Ligand-Target Pair

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