BindingDB PrimarySearch

Found 21 hits Enz. Inhib. hit(s) with all data for entry = 50010063
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090516 (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090517 (5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...) Show SMILES CC(C)c1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090519 (CHEMBL300519 \| [2-(5-Isopropyl-1H-indol-3-yl)-ethy...) Show SMILES CC(C)c1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090523 (2-(5-tert-Butyl-1-methyl-1H-indol-3-yl)-ethylamine...) Show SMILES Cn1cc(CCN)c2cc(ccc12)C(C)(C)C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090522 (5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-...) Show SMILES CCc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090521 (5-tert-Butyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole...) Show SMILES CC(C)(C)c1ccc2[nH]cc(CCN3CCCC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090515 (5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H...) Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(C)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090518 (5-Isopropyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole ...) Show SMILES CC(C)c1ccc2[nH]cc(CCN3CCCC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) Show SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090517 (5-Isopropyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)...) Show SMILES CC(C)c1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090519 (CHEMBL300519 \| [2-(5-Isopropyl-1H-indol-3-yl)-ethy...) Show SMILES CC(C)c1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090516 (5-tert-Butyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50049099 (CHEMBL50492 \| [2-(5-Ethyl-1H-indol-3-yl)-ethyl]-di...) Show SMILES CCc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50090520 (5-Ethyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole \| CH...) Show SMILES CCc1ccc2[nH]cc(CCN3CCCC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity for human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090522 (5-Ethyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-...) Show SMILES CCc1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) Show SMILES CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	DrugBank PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090515 (5-Methyl-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H...) Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(C)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50049099 (CHEMBL50492 \| [2-(5-Ethyl-1H-indol-3-yl)-ethyl]-di...) Show SMILES CCc1ccc2[nH]cc(CCN(C)C)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	286	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090521 (5-tert-Butyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole...) Show SMILES CC(C)(C)c1ccc2[nH]cc(CCN3CCCC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	312	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090518 (5-Isopropyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole ...) Show SMILES CC(C)c1ccc2[nH]cc(CCN3CCCC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	472	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50090520 (5-Ethyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole \| CH...) Show SMILES CCc1ccc2[nH]cc(CCN3CCCC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Allelix Corp. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 10: 1707-9 (2000) BindingDB Entry DOI: 10.7270/Q2GF0SRT
NPS Allelix Corp. Curated by ChEMBL					More data for this Ligand-Target Pair